REACTOME_NUCLEAR_ENVELOPE_BREAKDOWN | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | BANF1 | Barrier-to-autointegration factor | [1] | -2.49[2] | -2.63[3] | -3.15[4] | -2.63[5] | -2.70[6] | -3.02[7] |
2 | LMNA | Prelamin-A/C | [8] | -0.61[9] | -1.41[10] | -2.87[11] | -0.21[12] | -0.92[13] | -1.17[14] |
3 | SEC13 | Protein SEC13 homolog | [15] | -1.42[16] | -1.29[17] | -1.20[18] | -2.46[19] | -2.24[20] | -1.76[21] |
4 | NEK6 | Serine/threonine-protein kinase Nek6 | [22] | -0.55[23] | -0.41[24] | -1.03[25] | -1.24[26] | -1.60[27] | 0.12[28] |
5 | EMD | Emerin | [29] | -1.56[30] | -1.86[31] | -2.22[32] | -1.16[33] | -1.09[34] | -2.26[35] |
6 | CTDNEP1 | CTD nuclear envelope phosphatase 1 | [36] | 0.27[37] | -0.23[38] | -0.55[39] | -0.44[40] | -0.35[41] | -2.14[42] |
7 | RAE1 | mRNA export factor | [43] | 0.10[44] | -0.42[45] | -1.64[46] | -0.16[47] | -0.78[48] | -1.22[49] |
8 | VRK1 | Serine/threonine-protein kinase VRK1 | [50] | -2.00[51] | -1.44[52] | -1.60[53] | -1.37[54] | -1.31[55] | -3.32[56] |
9 | NUP88 | Nuclear pore complex protein Nup88 | [57] | -0.53[58] | -0.25[59] | -0.23[60] | -1.07[61] | -0.49[62] | 0.91[63] |
10 | TMPO | Lamina-associated polypeptide 2, isoform alpha | [64] | 0.48[65] | 1.01[66] | 1.19[67] | 1.42[68] | 1.38[69] | 0.60[70] |
11 | SEH1L | Nucleoporin SEH1 | [71] | -0.25[72] | 0.00[73] | 0.36[74] | -0.16[75] | -0.87[76] | -0.02[77] |
12 | LPIN2 | Phosphatidate phosphatase LPIN2 | [78] | 0.65[79] | 1.04[80] | 1.59[81] | 0.03[82] | -0.38[83] | 2.43[84] |
13 | NUP35 | Nucleoporin NUP53 | [85] | -1.56[86] | -1.22[87] | -1.33[88] | -1.83[89] | -1.97[90] | -1.42[91] |
14 | CCNB1 | G2/mitotic-specific cyclin-B1 | [92] | 1.37[93] | 1.37[94] | 1.46[95] | 0.87[96] | 1.92[97] | -2.55[98] |
15 | LMNB1 | Lamin-B1 | [99] | 0.51[100] | 0.30[101] | 0.26[102] | 0.57[103] | 0.29[104] | -2.40[105] |
16 | LEMD2 | LEM domain-containing protein 2 | [106] | 0.31[107] | 0.05[108] | -0.92[109] | 0.32[110] | -0.19[111] | -0.89[112] |
17 | NUP62 | Nuclear pore glycoprotein p62 | [113] | 0.70[114] | 0.07[115] | 1.03[116] | 0.47[117] | 0.63[118] | 0.22[119] |
18 | NEK9 | Serine/threonine-protein kinase Nek9 | [120] | 1.08[121] | 0.28[122] | 0.62[123] | 0.59[124] | 1.10[125] | 1.21[126] |
19 | NUP85 | Nuclear pore complex protein Nup85 | [127] | 0.27[128] | 0.38[129] | 0.54[130] | -0.16[131] | 0.11[132] | 0.02[133] |
20 | LPIN1 | Phosphatidate phosphatase LPIN1 | [134] | -2.06[135] | -0.48[136] | -1.64[137] | -0.21[138] | -1.08[139] | 1.25[140] |
21 | AAAS | Aladin | [141] | -0.21[142] | -0.13[143] | -0.63[144] | -0.52[145] | -0.41[146] | -0.39[147] |
22 | NUP50 | Nuclear pore complex protein Nup50 | [148] | 0.30[149] | 0.74[150] | 1.05[151] | 0.25[152] | 0.81[153] | 1.36[154] |
23 | RANBP2 | E3 SUMO-protein ligase RanBP2 | [155] | 0.00[156] | 1.45[157] | 1.10[158] | 0.80[159] | 1.02[160] | 2.75[161] |
24 | NUP93 | Nuclear pore complex protein Nup93 | [162] | 1.20[163] | 0.48[164] | 0.37[165] | 0.20[166] | 0.58[167] | -0.71[168] |
25 | NUP98 | Nuclear pore complex protein Nup98-Nup96 | [169] | 1.70[170] | 1.14[171] | 1.32[172] | 1.49[173] | 1.12[174] | 1.66[175] |
26 | NUP54 | Nucleoporin p54 | [176] | -0.37[177] | 0.03[178] | -0.06[179] | -0.41[180] | 0.14[181] | -0.19[182] |
27 | NUP107 | Nuclear pore complex protein Nup107 | [183] | 0.03[184] | 0.90[185] | 0.80[186] | 0.56[187] | 0.55[188] | -0.20[189] |
28 | CDK1 | Cyclin-dependent kinase 1 | [190] | 0.78[191] | 2.60[192] | 1.24[193] | 1.53[194] | 2.42[195] | -2.67[196] |
29 | NUP37 | Nucleoporin Nup37 | [197] | 0.19[198] | 0.23[199] | 0.23[200] | -0.29[201] | -0.22[202] | -1.63[203] |
30 | TPR | Nucleoprotein TPR | [204] | 0.16[205] | 1.78[206] | 2.00[207] | 1.81[208] | 2.11[209] | 2.39[210] |
31 | PLK1 | Serine/threonine-protein kinase PLK1 | [211] | 2.02[212] | 1.52[213] | 1.29[214] | 0.51[215] | 1.62[216] | -2.83[217] |
32 | VRK2 | Serine/threonine-protein kinase VRK2 | [218] | -1.54[219] | -0.64[220] | -1.91[221] | -0.94[222] | -1.23[223] | -0.80[224] |
33 | NUP160 | Nuclear pore complex protein Nup160 | [225] | 1.38[226] | 1.29[227] | 1.80[228] | 0.44[229] | 0.81[230] | 1.27[231] |
34 | NEK7 | Serine/threonine-protein kinase Nek7 | [232] | -1.16[233] | 0.53[234] | 0.40[235] | 3.10[236] | 1.54[237] | 1.70[238] |
35 | POM121 | Nuclear envelope pore membrane protein POM 121 | [239] | 0.97[240] | 1.08[241] | 0.83[242] | 0.81[243] | 0.33[244] | 1.09[245] |
36 | NUP133 | Nuclear pore complex protein Nup133 | [246] | 0.71[247] | 0.82[248] | 1.69[249] | 1.47[250] | 0.89[251] | 0.85[252] |
37 | NUP153 | Nuclear pore complex protein Nup153 | [253] | 1.92[254] | 1.88[255] | 1.43[256] | 2.52[257] | 1.75[258] | 1.74[259] |
38 | NUP43 | Nucleoporin Nup43 | [260] | 1.44[261] | 1.37[262] | 1.04[263] | 1.35[264] | 1.15[265] | 0.11[266] |
39 | NUP205 | Nuclear pore complex protein Nup205 | [267] | 1.71[268] | 1.38[269] | 2.47[270] | 2.04[271] | 2.29[272] | 1.31[273] |
40 | POM121C | Nuclear envelope pore membrane protein POM 121C | [274] | 0.81[275] | -0.17[276] | -0.59[277] | 0.66[278] | 0.16[279] | 0.23[280] |
41 | CNEP1R1 | Nuclear envelope phosphatase-regulatory subunit 1 | [281] | -0.05[282] | -0.16[283] | -0.84[284] | -0.31[285] | -0.40[286] | -0.31[287] |
42 | NUP214 | Nuclear pore complex protein Nup214 | [288] | 1.55[289] | 0.62[290] | 1.66[291] | 1.45[292] | 1.45[293] | 1.55[294] |
43 | NUP188 | Nucleoporin NUP188 homolog | [295] | 2.79[296] | 1.93[297] | 2.48[298] | 1.78[299] | 3.02[300] | 1.62[301] |
44 | NUP210 | Nuclear pore membrane glycoprotein 210 | [302] | 3.23[303] | 2.80[304] | 3.81[305] | 1.37[306] | -0.17[307] | 2.79[308] |
45 | PRKCA | Protein kinase C alpha type | [309] | 2.36[310] | 2.16[311] | 2.43[312] | 1.41[313] | 1.84[314] | 1.72[315] |
46 | LEMD3 | Inner nuclear membrane protein Man1 | [316] | 0.42[317] | 1.16[318] | 1.02[319] | 0.48[320] | 1.03[321] | 1.26[322] |
47 | NUP155 | Nuclear pore complex protein Nup155 | [323] | 1.64[324] | 1.01[325] | 1.90[326] | 1.74[327] | 2.68[328] | 1.54[329] |
48 | CCNB2 | G2/mitotic-specific cyclin-B2 | [330] | 1.62[331] | 2.14[332] | 2.43[333] | 1.79[334] | 2.84[335] | -1.80[336] |
49 | LPIN3 | Phosphatidate phosphatase LPIN3 | [337] | 1.10[338] | 1.88[339] | -0.10[340] | 0.67[341] | 0.34[342] | 3.47[343] |
50 | PRKCB | Protein kinase C beta type | [344] | -7.29[345] | -6.33[346] | [347] | 1.75[348] | -3.49[349] | 3.33[350] |
51 | NUP42 | [351] | [352] | [353] | [354] | [355] | [356] | [357] | |
52 | NDC1 | Nucleoporin NDC1 | [358] | [359] | [360] | [361] | [362] | [363] | [364] |
53 | NUP58 | Nucleoporin p58/p45 | [365] | [366] | [367] | [368] | [369] | [370] | [371] |