REACTOME_NR1H2_NR1H3_REGULATE_GENE_EXPRESSION_TO_CONTROL_BILE_ACID_HOMEOSTASIS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 NR1H3 Oxysterols receptor LXR-alpha [1] -2.04[2] -0.91[3] -0.42[4] -3.62[5] -4.62[6] -1.79[7]
2 RXRA Retinoic acid receptor RXR-alpha [8] -0.42[9] -0.52[10] -0.11[11] -0.88[12] -0.86[13] 0.67[14]
3 NR1H2 Oxysterols receptor LXR-beta [15] -1.05[16] -1.06[17] -1.14[18] -1.14[19] -0.44[20] -1.46[21]
4 NCOR1 Nuclear receptor corepressor 1 [22] 0.71[23] 1.32[24] 1.53[25] 0.68[26] 1.07[27] 1.32[28]
5 RXRB Retinoic acid receptor RXR-beta [29] 0.65[30] 1.08[31] -0.43[32] 0.69[33] -0.08[34] -1.37[35]
6 UGT1A3 UDP-glucuronosyltransferase 1-3 [36] -3.33[37] [38] -10.32[39] -7.30[40] -12.07[41] -0.24[42]
7 NCOR2 Nuclear receptor corepressor 2 [43] 2.98[44] 1.48[45] 1.14[46] 3.26[47] 3.10[48] 0.41[49]
8 NCOA1 Nuclear receptor coactivator 1 [50] 0.10[51] 0.77[52] 0.53[53] 0.91[54] 0.70[55] 1.17[56]
9 FABP6 Gastrotropin [57] [58] [59] [60] [61] [62] [63]
[1]
ref_hepatocyte NR1H3
Mean 14.8
Standard deviation 10
Values 6.4 9.6 6.4 22 29
[2]
HepG2 NR1H3
Mean 10.3
Standard deviation 0.1
Values 10 10
[3]
HepG2.C3A NR1H3
Mean 18.6
Standard deviation 4.7
Values 22 15
[4]
HuH.7 NR1H3
Mean 33.8
Standard deviation 2.7
Values 31 36 35
[5]
SNU475 NR1H3
Mean 4.08
Standard deviation 1.1
Values 3.3 4.8
[6]
THLE NR1H3
Mean 1.8
Standard deviation 0.21
Values 1.7 1.9
[7]
liver NR1H3
Mean 16.9
Standard deviation 7.5
Values 25 12 21 9.7
[8]
ref_hepatocyte RXRA
Mean 14.5
Standard deviation 6.1
Values 15 7.5 9.4 22 18
[9]
HepG2 RXRA
Mean 30.9
Standard deviation 2.8
Values 33 29
[10]
HepG2.C3A RXRA
Mean 23.9
Standard deviation 6.1
Values 28 20
[11]
HuH.7 RXRA
Mean 41.2
Standard deviation 10
Values 42 51 30
[12]
SNU475 RXRA
Mean 26.9
Standard deviation 8.3
Values 33 21
[13]
THLE RXRA
Mean 23.9
Standard deviation 7.5
Values 19 29
[14]
liver RXRA
Mean 91.4
Standard deviation 37
Values 1.3e+02 72 49 1.2e+02
[15]
ref_hepatocyte NR1H2
Mean 12.9
Standard deviation 7.5
Values 2.8 8 19 20 14
[16]
HepG2 NR1H2
Mean 17.7
Standard deviation 3.5
Values 20 15
[17]
HepG2.C3A NR1H2
Mean 14.5
Standard deviation 1.7
Values 16 13
[18]
HuH.7 NR1H2
Mean 17.9
Standard deviation 2.7
Values 19 15 20
[19]
SNU475 NR1H2
Mean 19.9
Standard deviation 0.35
Values 20 20
[20]
THLE NR1H2
Mean 28.5
Standard deviation 1.7
Values 27 30
[21]
liver NR1H2
Mean 18.5
Standard deviation 8.5
Values 27 11 25 11
[22]
ref_hepatocyte NCOR1
Mean 7.02
Standard deviation 2.9
Values 10 10 5.5 4.3 5.1
[23]
HepG2 NCOR1
Mean 32.8
Standard deviation 11
Values 25 41
[24]
HepG2.C3A NCOR1
Mean 41.3
Standard deviation 1.3
Values 40 42
[25]
HuH.7 NCOR1
Mean 62.2
Standard deviation 16
Values 78 63 46
[26]
SNU475 NCOR1
Mean 38.2
Standard deviation 4.6
Values 42 35
[27]
THLE NCOR1
Mean 44.2
Standard deviation 1.4
Values 43 45
[28]
liver NCOR1
Mean 69.4
Standard deviation 14
Values 87 68 52 70
[29]
ref_hepatocyte RXRB
Mean 5.01
Standard deviation 2.9
Values 1.6 2.1 7.3 7.1 7
[30]
HepG2 RXRB
Mean 22.3
Standard deviation 2
Values 21 24
[31]
HepG2.C3A RXRB
Mean 24.9
Standard deviation 2.8
Values 27 23
[32]
HuH.7 RXRB
Mean 11.3
Standard deviation 2.4
Values 9.8 10 14
[33]
SNU475 RXRB
Mean 27.5
Standard deviation 6.1
Values 32 23
[34]
THLE RXRB
Mean 14.2
Standard deviation 0.3
Values 14 14
[35]
liver RXRB
Mean 7.69
Standard deviation 0.73
Values 8 6.6 7.9 8.2
[36]
ref_hepatocyte UGT1A3
Mean 4.24
Standard deviation 4.8
Values 0 2.3 0.37 7.9 11
[37]
HepG2 UGT1A3
Mean 1.2
Standard deviation 0.2
Values 1.3 1.1
[38]
HepG2.C3A UGT1A3
Mean 0
Standard deviation 0
Values 0 0
[39]
HuH.7 UGT1A3
Mean 0.0101
Standard deviation 0.0024
Values 0.0082 0.013 0.0094
[40]
SNU475 UGT1A3
Mean 0.0911
Standard deviation 0.029
Values 0.11 0.071
[41]
THLE UGT1A3
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[42]
liver UGT1A3
Mean 14.2
Standard deviation 12
Values 2.5 21 28 5.8
[43]
ref_hepatocyte NCOR2
Mean 2.59
Standard deviation 0.92
Values 2.5 2.2 4.1 2.4 1.7
[44]
HepG2 NCOR2
Mean 58.1
Standard deviation 18
Values 71 46
[45]
HepG2.C3A NCOR2
Mean 17
Standard deviation 4.1
Values 20 14
[46]
HuH.7 NCOR2
Mean 17.5
Standard deviation 6.7
Values 25 14 13
[47]
SNU475 NCOR2
Mean 84.3
Standard deviation 15
Values 95 73
[48]
THLE NCOR2
Mean 66.6
Standard deviation 7.4
Values 61 72
[49]
liver NCOR2
Mean 13.6
Standard deviation 4.9
Values 11 14 8.8 20
[50]
ref_hepatocyte NCOA1
Mean 2.09
Standard deviation 0.73
Values 1.8 2 1.1 2.8 2.8
[51]
HepG2 NCOA1
Mean 6.38
Standard deviation 1.4
Values 5.4 7.4
[52]
HepG2.C3A NCOA1
Mean 8.42
Standard deviation 0.79
Values 7.9 9
[53]
HuH.7 NCOA1
Mean 9.25
Standard deviation 2.7
Values 9.2 12 6.6
[54]
SNU475 NCOA1
Mean 13.3
Standard deviation 1
Values 14 13
[55]
THLE NCOA1
Mean 10.2
Standard deviation 0.47
Values 9.9 11
[56]
liver NCOA1
Mean 18.7
Standard deviation 4.8
Values 17 23 13 22
[57]
ref_hepatocyte FABP6
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[58]
HepG2 FABP6
Mean 0.127
Standard deviation 0.095
Values 0.19 0.06
[59]
HepG2.C3A FABP6
Mean 0.0409
Standard deviation 0.0028
Values 0.039 0.043
[60]
HuH.7 FABP6
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[61]
SNU475 FABP6
Mean 0.146
Standard deviation 0.0091
Values 0.14 0.15
[62]
THLE FABP6
Mean 0.00562
Standard deviation 0.00042
Values 0.0059 0.0053
[63]
liver FABP6
Mean 0
Standard deviation 0
Values 0 0 0 0