REACTOME_NR1H2_NR1H3_REGULATE_GENE_EXPRESSION_LINKED_TO_LIPOGENESIS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 SCD Acyl-CoA desaturase [1] -0.18[2] 0.39[3] 0.48[4] -1.45[5] -2.00[6] -0.23[7]
2 ANGPTL3 Angiopoietin-related protein 3 [8] -10.23[9] -7.62[10] -3.84[11] -10.62[12] -9.93[13] -0.55[14]
3 SREBF1 Sterol regulatory element-binding protein 1 [15] -0.33[16] -1.30[17] -1.44[18] -0.01[19] 0.54[20] -0.23[21]
4 FASN Fatty acid synthase [22] 2.85[23] 2.23[24] 2.11[25] 2.26[26] 2.66[27] 1.78[28]
5 NR1H3 Oxysterols receptor LXR-alpha [29] -1.22[30] -1.46[31] -1.22[32] -1.21[33] -2.18[34] -1.04[35]
6 RXRA Retinoic acid receptor RXR-alpha [36] 0.39[37] -1.07[38] -0.91[39] 1.54[40] 1.58[41] 1.42[42]
7 NR1H2 Oxysterols receptor LXR-beta [43] -0.24[44] -1.61[45] -1.93[46] 1.28[47] 2.00[48] -0.71[49]
8 RXRB Retinoic acid receptor RXR-beta [50] 1.46[51] 0.53[52] -1.23[53] 3.11[54] 2.36[55] -0.61[56]
9 NRIP1 Nuclear receptor-interacting protein 1 [57] 2.06[58] 2.09[59] 0.16[60] 4.46[61] 4.02[62] 1.88[63]
[1]
ref_hepatocyte SCD
Mean 184
Standard deviation 1.7e+02
Values 4.1e+02 33 35 1.3e+02 3.1e+02
[2]
HepG2 SCD
Mean 263
Standard deviation 44
Values 2.3e+02 2.9e+02
[3]
HepG2.C3A SCD
Mean 832
Standard deviation 2.9e+02
Values 1e+03 6.3e+02
[4]
HuH.7 SCD
Mean 1.37e+03
Standard deviation 3.6e+02
Values 1.4e+03 1.7e+03 1e+03
[5]
SNU475 SCD
Mean 42.8
Standard deviation 2.4
Values 45 41
[6]
THLE SCD
Mean 25.4
Standard deviation 2.3
Values 24 27
[7]
liver SCD
Mean 369
Standard deviation 2.8e+02
Values 1.1e+02 5.6e+02 6.7e+02 1.4e+02
[8]
ref_hepatocyte ANGPTL3
Mean 90.5
Standard deviation 1.2e+02
Values 0.88 33 5.8 1.5e+02 2.7e+02
[9]
HepG2 ANGPTL3
Mean 0.122
Standard deviation 0.076
Values 0.069 0.18
[10]
HepG2.C3A ANGPTL3
Mean 1.59
Standard deviation 0.21
Values 1.7 1.4
[11]
HuH.7 ANGPTL3
Mean 33.7
Standard deviation 10
Values 29 45 27
[12]
SNU475 ANGPTL3
Mean 0.0367
Standard deviation 0.013
Values 0.028 0.046
[13]
THLE ANGPTL3
Mean 0.0512
Standard deviation 0.02
Values 0.065 0.037
[14]
liver ANGPTL3
Mean 145
Standard deviation 86
Values 2.4e+02 1e+02 2e+02 48
[15]
ref_hepatocyte SREBF1
Mean 27.4
Standard deviation 36
Values 1.8 1.2 6.5 42 85
[16]
HepG2 SREBF1
Mean 35.4
Standard deviation 8.8
Values 42 29
[17]
HepG2.C3A SREBF1
Mean 38.3
Standard deviation 21
Values 53 24
[18]
HuH.7 SREBF1
Mean 53.8
Standard deviation 3.4
Values 50 55 56
[19]
SNU475 SREBF1
Mean 17.3
Standard deviation 4.1
Values 20 14
[20]
THLE SREBF1
Mean 21.9
Standard deviation 0.74
Values 21 22
[21]
liver SREBF1
Mean 54.7
Standard deviation 14
Values 58 59 67 35
[22]
ref_hepatocyte FASN
Mean 16.9
Standard deviation 11
Values 31 3.5 11 17 22
[23]
HepG2 FASN
Mean 197
Standard deviation 11
Values 1.9e+02 2e+02
[24]
HepG2.C3A FASN
Mean 273
Standard deviation 1.4e+02
Values 3.7e+02 1.7e+02
[25]
HuH.7 FASN
Mean 387
Standard deviation 1.1e+02
Values 5e+02 3.8e+02 2.9e+02
[26]
SNU475 FASN
Mean 51.5
Standard deviation 12
Values 60 43
[27]
THLE FASN
Mean 59
Standard deviation 19
Values 46 72
[28]
liver FASN
Mean 136
Standard deviation 1e+02
Values 92 1.2e+02 54 2.8e+02
[29]
ref_hepatocyte NR1H3
Mean 14.8
Standard deviation 10
Values 6.4 9.6 6.4 22 29
[30]
HepG2 NR1H3
Mean 10.3
Standard deviation 0.1
Values 10 10
[31]
HepG2.C3A NR1H3
Mean 18.6
Standard deviation 4.7
Values 22 15
[32]
HuH.7 NR1H3
Mean 33.8
Standard deviation 2.7
Values 31 36 35
[33]
SNU475 NR1H3
Mean 4.08
Standard deviation 1.1
Values 3.3 4.8
[34]
THLE NR1H3
Mean 1.8
Standard deviation 0.21
Values 1.7 1.9
[35]
liver NR1H3
Mean 16.9
Standard deviation 7.5
Values 25 12 21 9.7
[36]
ref_hepatocyte RXRA
Mean 14.5
Standard deviation 6.1
Values 15 7.5 9.4 22 18
[37]
HepG2 RXRA
Mean 30.9
Standard deviation 2.8
Values 33 29
[38]
HepG2.C3A RXRA
Mean 23.9
Standard deviation 6.1
Values 28 20
[39]
HuH.7 RXRA
Mean 41.2
Standard deviation 10
Values 42 51 30
[40]
SNU475 RXRA
Mean 26.9
Standard deviation 8.3
Values 33 21
[41]
THLE RXRA
Mean 23.9
Standard deviation 7.5
Values 19 29
[42]
liver RXRA
Mean 91.4
Standard deviation 37
Values 1.3e+02 72 49 1.2e+02
[43]
ref_hepatocyte NR1H2
Mean 12.9
Standard deviation 7.5
Values 2.8 8 19 20 14
[44]
HepG2 NR1H2
Mean 17.7
Standard deviation 3.5
Values 20 15
[45]
HepG2.C3A NR1H2
Mean 14.5
Standard deviation 1.7
Values 16 13
[46]
HuH.7 NR1H2
Mean 17.9
Standard deviation 2.7
Values 19 15 20
[47]
SNU475 NR1H2
Mean 19.9
Standard deviation 0.35
Values 20 20
[48]
THLE NR1H2
Mean 28.5
Standard deviation 1.7
Values 27 30
[49]
liver NR1H2
Mean 18.5
Standard deviation 8.5
Values 27 11 25 11
[50]
ref_hepatocyte RXRB
Mean 5.01
Standard deviation 2.9
Values 1.6 2.1 7.3 7.1 7
[51]
HepG2 RXRB
Mean 22.3
Standard deviation 2
Values 21 24
[52]
HepG2.C3A RXRB
Mean 24.9
Standard deviation 2.8
Values 27 23
[53]
HuH.7 RXRB
Mean 11.3
Standard deviation 2.4
Values 9.8 10 14
[54]
SNU475 RXRB
Mean 27.5
Standard deviation 6.1
Values 32 23
[55]
THLE RXRB
Mean 14.2
Standard deviation 0.3
Values 14 14
[56]
liver RXRB
Mean 7.69
Standard deviation 0.73
Values 8 6.6 7.9 8.2
[57]
ref_hepatocyte NRIP1
Mean 3.23
Standard deviation 1.9
Values 6.5 2.9 3 1.5 2.2
[58]
HepG2 NRIP1
Mean 21.8
Standard deviation 7
Values 17 27
[59]
HepG2.C3A NRIP1
Mean 47.3
Standard deviation 8.4
Values 41 53
[60]
HuH.7 NRIP1
Mean 19.2
Standard deviation 8.7
Values 17 29 12
[61]
SNU475 NRIP1
Mean 45.2
Standard deviation 4.6
Values 42 48
[62]
THLE NRIP1
Mean 29
Standard deviation 7.8
Values 35 23
[63]
liver NRIP1
Mean 28
Standard deviation 18
Values 15 43 11 44