REACTOME_NOTCH2_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 HES1 Transcription factor HES-1 [1] -1.61[2] -4.08[3] -2.86[4] -3.39[5] -4.54[6] -3.52[7]
2 NOTCH2 Neurogenic locus notch homolog protein 2 [8] -1.05[9] -6.74[10] -0.30[11] 0.92[12] 1.39[13] 1.21[14]
3 RBPJ Recombining binding protein suppressor of hairless [15] 0.16[16] 0.77[17] 0.74[18] -0.10[19] -0.48[20] -0.26[21]
4 EP300 Histone acetyltransferase p300 [22] 1.54[23] 1.17[24] 1.03[25] 0.46[26] 0.19[27] 0.64[28]
5 MAML1 Mastermind-like protein 1 [29] 0.93[30] 0.93[31] 0.44[32] 0.13[33] -0.06[34] -1.04[35]
6 CREB1 Cyclic AMP-responsive element-binding protein 1 [36] 0.54[37] 1.74[38] 1.19[39] 0.43[40] 0.05[41] 0.22[42]
7 MAMLD1 Mastermind-like domain-containing protein 1 [43] -3.08[44] -9.54[45] -4.32[46] -1.06[47] -1.56[48] -2.45[49]
8 MAML3 Mastermind-like protein 3 [50] -1.56[51] -0.78[52] 1.21[53] -0.71[54] -2.42[55] 1.38[56]
9 GZMB Granzyme B [57] -5.80[58] [59] [60] [61] [62] -2.83[63]
10 MAML2 Mastermind-like protein 2 [64] 2.31[65] 2.97[66] -4.64[67] 2.66[68] 1.21[69] 0.24[70]
11 FCER2 Low affinity immunoglobulin epsilon Fc receptor [71] [72] [73] [74] [75] [76] -2.55[77]
12 HES5 Transcription factor HES-5 [78] 2.05[79] -2.14[80] [81] [82] -4.80[83] -1.74[84]
[1]
ref_hepatocyte HES1
Mean 7.15
Standard deviation 5.3
Values 9.1 1 3.7 15 7
[2]
HepG2 HES1
Mean 11.7
Standard deviation 5.7
Values 16 7.7
[3]
HepG2.C3A HES1
Mean 1.84
Standard deviation 0.56
Values 2.2 1.4
[4]
HuH.7 HES1
Mean 8.41
Standard deviation 1.4
Values 6.9 8.7 9.7
[5]
SNU475 HES1
Mean 5.42
Standard deviation 0.41
Values 5.7 5.1
[6]
THLE HES1
Mean 3.42
Standard deviation 0.023
Values 3.4 3.4
[7]
liver HES1
Mean 3.86
Standard deviation 1.7
Values 6.2 3 4.1 2.2
[8]
ref_hepatocyte NOTCH2
Mean 5.26
Standard deviation 4
Values 1.6 11 7.1 2.4 3.7
[9]
HepG2 NOTCH2
Mean 12.7
Standard deviation 3.4
Values 15 10
[10]
HepG2.C3A NOTCH2
Mean 0.213
Standard deviation 0.12
Values 0.13 0.3
[11]
HuH.7 NOTCH2
Mean 36.5
Standard deviation 12
Values 44 43 23
[12]
SNU475 NOTCH2
Mean 79.3
Standard deviation 13
Values 88 70
[13]
THLE NOTCH2
Mean 154
Standard deviation 35
Values 1.3e+02 1.8e+02
[14]
liver NOTCH2
Mean 74.9
Standard deviation 42
Values 39 1.2e+02 39 99
[15]
ref_hepatocyte RBPJ
Mean 3.53
Standard deviation 1.3
Values 5.4 3.5 3.8 2.1 2.8
[16]
HepG2 RBPJ
Mean 19.7
Standard deviation 8.2
Values 14 26
[17]
HepG2.C3A RBPJ
Mean 26.2
Standard deviation 1.4
Values 25 27
[18]
HuH.7 RBPJ
Mean 50.4
Standard deviation 6.7
Values 58 49 45
[19]
SNU475 RBPJ
Mean 26.3
Standard deviation 0.26
Values 26 26
[20]
THLE RBPJ
Mean 28.1
Standard deviation 3.7
Values 26 31
[21]
liver RBPJ
Mean 18.1
Standard deviation 2.4
Values 21 19 17 16
[22]
ref_hepatocyte EP300
Mean 2.46
Standard deviation 1.2
Values 3 1.8 4.4 1.4 1.8
[23]
HepG2 EP300
Mean 35.9
Standard deviation 5.7
Values 32 40
[24]
HepG2.C3A EP300
Mean 24.1
Standard deviation 1.4
Values 23 25
[25]
HuH.7 EP300
Mean 43
Standard deviation 15
Values 55 48 26
[26]
SNU475 EP300
Mean 26.9
Standard deviation 1.3
Values 28 26
[27]
THLE EP300
Mean 31.2
Standard deviation 11
Values 23 39
[28]
liver EP300
Mean 23.6
Standard deviation 8
Values 20 27 15 33
[29]
ref_hepatocyte MAML1
Mean 2.18
Standard deviation 1.5
Values 4.8 1.9 2.1 1.1 1
[30]
HepG2 MAML1
Mean 20.9
Standard deviation 0.74
Values 20 21
[31]
HepG2.C3A MAML1
Mean 18.1
Standard deviation 1.4
Values 19 17
[32]
HuH.7 MAML1
Mean 25.3
Standard deviation 3.3
Values 29 23 24
[33]
SNU475 MAML1
Mean 19
Standard deviation 0.56
Values 19 19
[34]
THLE MAML1
Mean 23.3
Standard deviation 2.6
Values 21 25
[35]
liver MAML1
Mean 6.56
Standard deviation 1.8
Values 6 5.9 5.1 9.3
[36]
ref_hepatocyte CREB1
Mean 1.8
Standard deviation 1.2
Values 3.7 2.1 1.5 0.96 0.81
[37]
HepG2 CREB1
Mean 13.1
Standard deviation 2.8
Values 11 15
[38]
HepG2.C3A CREB1
Mean 26.1
Standard deviation 3.2
Values 24 28
[39]
HuH.7 CREB1
Mean 35.1
Standard deviation 4
Values 38 36 31
[40]
SNU475 CREB1
Mean 19.3
Standard deviation 0.081
Values 19 19
[41]
THLE CREB1
Mean 20.8
Standard deviation 2.1
Values 22 19
[42]
liver CREB1
Mean 13
Standard deviation 3.1
Values 12 16 9.3 15
[43]
ref_hepatocyte MAMLD1
Mean 0.833
Standard deviation 1.1
Values 0 0.39 2.7 0.16 0.94
[44]
HepG2 MAMLD1
Mean 0.493
Standard deviation 0.22
Values 0.34 0.65
[45]
HepG2.C3A MAMLD1
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[46]
HuH.7 MAMLD1
Mean 0.356
Standard deviation 0.046
Values 0.31 0.35 0.4
[47]
SNU475 MAMLD1
Mean 3.17
Standard deviation 0.79
Values 2.6 3.7
[48]
THLE MAMLD1
Mean 3.14
Standard deviation 0.38
Values 3.4 2.9
[49]
liver MAMLD1
Mean 0.94
Standard deviation 0.39
Values 1.1 0.64 1.4 0.62
[50]
ref_hepatocyte MAML3
Mean 0.411
Standard deviation 0.24
Values 0 0.58 0.59 0.46 0.43
[51]
HepG2 MAML3
Mean 0.699
Standard deviation 0.024
Values 0.72 0.68
[52]
HepG2.C3A MAML3
Mean 1.04
Standard deviation 0.079
Values 0.98 1.1
[53]
HuH.7 MAML3
Mean 8.13
Standard deviation 2.1
Values 9.1 9.5 5.8
[54]
SNU475 MAML3
Mean 1.99
Standard deviation 0.56
Values 2.4 1.6
[55]
THLE MAML3
Mean 0.858
Standard deviation 0.2
Values 0.72 1
[56]
liver MAML3
Mean 6.6
Standard deviation 2.8
Values 4.4 9.7 4 8.3
[57]
ref_hepatocyte GZMB
Mean 0.318
Standard deviation 0.4
Values 0 0.39 0.23 0 0.98
[58]
HepG2 GZMB
Mean 0.0286
Standard deviation 0.0081
Values 0.023 0.034
[59]
HepG2.C3A GZMB
Mean 0
Standard deviation 0
Values 0 0
[60]
HuH.7 GZMB
Mean 0
Standard deviation 0
Values 0 0 0
[61]
SNU475 GZMB
Mean 0
Standard deviation 0
Values 0 0
[62]
THLE GZMB
Mean 0
Standard deviation 0
Values 0 0
[63]
liver GZMB
Mean 0.276
Standard deviation 0.29
Values 0.59 0.029 0.46 0.026
[64]
ref_hepatocyte MAML2
Mean 0.226
Standard deviation 0.3
Values 0.69 0 0.36 0 0.089
[65]
HepG2 MAML2
Mean 5.61
Standard deviation 0.32
Values 5.8 5.4
[66]
HepG2.C3A MAML2
Mean 7.69
Standard deviation 1.2
Values 8.6 6.8
[67]
HuH.7 MAML2
Mean 0.0778
Standard deviation 0.056
Values 0.13 0.083 0.019
[68]
SNU475 MAML2
Mean 11.4
Standard deviation 0.01
Values 11 11
[69]
THLE MAML2
Mean 5.83
Standard deviation 0.93
Values 5.2 6.5
[70]
liver MAML2
Mean 1.66
Standard deviation 0.64
Values 1.1 1.9 1.2 2.4
[71]
ref_hepatocyte FCER2
Mean 0.051
Standard deviation 0.086
Values 0 0 0 0.2 0.057
[72]
HepG2 FCER2
Mean 0
Standard deviation 0
Values 0 0
[73]
HepG2.C3A FCER2
Mean 0
Standard deviation 0
Values 0 0
[74]
HuH.7 FCER2
Mean 0
Standard deviation 0
Values 0 0 0
[75]
SNU475 FCER2
Mean 0
Standard deviation 0
Values 0 0
[76]
THLE FCER2
Mean 0
Standard deviation 0
Values 0 0
[77]
liver FCER2
Mean 0.0536
Standard deviation 0.07
Values 0.047 0 0.15 0.013
[78]
ref_hepatocyte HES5
Mean 0.0207
Standard deviation 0.046
Values 0 0 0 0.1 0
[79]
HepG2 HES5
Mean 0.43
Standard deviation 0.39
Values 0.7 0.15
[80]
HepG2.C3A HES5
Mean 0.0204
Standard deviation 0.0014
Values 0.019 0.021
[81]
HuH.7 HES5
Mean 0
Standard deviation 0
Values 0 0 0
[82]
SNU475 HES5
Mean 0
Standard deviation 0
Values 0 0
[83]
THLE HES5
Mean 0.00828
Standard deviation 0.0033
Values 0.0059 0.011
[84]
liver HES5
Mean 0.0382
Standard deviation 0.05
Values 0.047 0 0 0.11