REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 SLC22A1 Solute carrier family 22 member 1 [1] -9.02[2] -7.63[3] -11.14[4] -10.05[5] -10.36[6] -0.10[7]
2 MAOA Amine oxidase [flavin-containing] A [8] -1.35[9] -0.75[10] 0.55[11] -4.39[12] 1.35[13] 0.23[14]
3 VAMP2 Vesicle-associated membrane protein 2 [15] 0.50[16] 0.68[17] 0.07[18] -0.22[19] 0.15[20] -1.47[21]
4 PPFIA1 Liprin-alpha-1 [22] 3.44[23] 3.02[24] 2.91[25] 4.44[26] 2.72[27] 0.55[28]
5 UNC13B Protein unc-13 homolog B [29] 3.61[30] 3.54[31] 3.25[32] 0.62[33] 1.78[34] 1.30[35]
6 RAB3A Ras-related protein Rab-3A [36] 1.77[37] 0.52[38] 1.70[39] -0.56[40] 0.19[41] -2.49[42]
7 SLC18A2 Synaptic vesicular amine transporter [43] 0.82[44] 2.98[45] 2.38[46] 0.02[47] 1.30[48] 2.02[49]
8 STX1A Syntaxin-1A [50] 2.79[51] 2.57[52] 0.12[53] 2.84[54] 2.41[55] -2.44[56]
9 STXBP1 Syntaxin-binding protein 1 [57] 3.58[58] 3.80[59] 3.27[60] 4.45[61] 4.86[62] -0.44[63]
10 CPLX1 Complexin-1 [64] 0.93[65] -0.31[66] 3.56[67] -2.64[68] -2.12[69] -1.08[70]
11 PPFIA3 Liprin-alpha-3 [71] 4.56[72] 4.80[73] 3.83[74] 1.14[75] 1.28[76] -1.19[77]
12 SNAP25 Synaptosomal-associated protein 25 [78] -1.65[79] -1.64[80] 3.08[81] 2.71[82] 5.31[83] -0.24[84]
13 SYT1 Synaptotagmin-1 [85] -0.25[86] -1.19[87] 6.49[88] 7.44[89] 4.17[90] 2.94[91]
14 SLC22A2 Solute carrier family 22 member 2 [92] [93] -1.06[94] -2.14[95] 0.19[96] 0.05[97] [98]
15 PPFIA2 Liprin-alpha-2 [99] 6.03[100] 8.77[101] 7.14[102] 0.97[103] 1.95[104] 5.62[105]
16 TSPOAP1 Peripheral-type benzodiazepine receptor-associated protein 1 [106] [107] [108] [109] [110] [111] [112]
17 RIMS1 Regulating synaptic membrane exocytosis protein 1 [113] [114] [115] [116] [117] [118] [119]
18 PPFIA4 Liprin-alpha-4 [120] [121] [122] [123] [124] [125] [126]
[1]
ref_hepatocyte SLC22A1
Mean 98.8
Standard deviation 1.2e+02
Values 0 2.5 42 1.9e+02 2.6e+02
[2]
HepG2 SLC22A1
Mean 0.117
Standard deviation 0.052
Values 0.08 0.15
[3]
HepG2.C3A SLC22A1
Mean 0.311
Standard deviation 0.14
Values 0.41 0.21
[4]
HuH.7 SLC22A1
Mean 0.0506
Standard deviation 0.035
Values 0.025 0.09 0.037
[5]
SNU475 SLC22A1
Mean 0.144
Standard deviation 0.039
Values 0.17 0.12
[6]
THLE SLC22A1
Mean 0.0887
Standard deviation 0.05
Values 0.12 0.053
[7]
liver SLC22A1
Mean 317
Standard deviation 1.8e+02
Values 5.4e+02 2.2e+02 3.7e+02 1.4e+02
[8]
ref_hepatocyte MAOA
Mean 22.1
Standard deviation 16
Values 3.4 23 8.6 34 41
[9]
HepG2 MAOA
Mean 5.32
Standard deviation 0.22
Values 5.5 5.2
[10]
HepG2.C3A MAOA
Mean 8.16
Standard deviation 2.3
Values 9.8 6.5
[11]
HuH.7 MAOA
Mean 37.5
Standard deviation 10
Values 36 49 28
[12]
SNU475 MAOA
Mean 1.62
Standard deviation 0.75
Values 1.1 2.1
[13]
THLE MAOA
Mean 66.1
Standard deviation 1.4
Values 67 65
[14]
liver MAOA
Mean 88.9
Standard deviation 19
Values 1.1e+02 90 88 65
[15]
ref_hepatocyte VAMP2
Mean 7.38
Standard deviation 2
Values 9.9 5.1 8 8.2 5.7
[16]
HepG2 VAMP2
Mean 6.41
Standard deviation 1.5
Values 7.4 5.4
[17]
HepG2.C3A VAMP2
Mean 7.34
Standard deviation 3
Values 9.5 5.2
[18]
HuH.7 VAMP2
Mean 8.97
Standard deviation 0.78
Values 8.3 8.8 9.8
[19]
SNU475 VAMP2
Mean 9.81
Standard deviation 1.6
Values 11 8.7
[20]
THLE VAMP2
Mean 9.61
Standard deviation 0.14
Values 9.5 9.7
[21]
liver VAMP2
Mean 9.18
Standard deviation 10
Values 22 1 11 1.9
[22]
ref_hepatocyte PPFIA1
Mean 4.38
Standard deviation 1.7
Values 4 5.6 6.7 2.7 2.9
[23]
HepG2 PPFIA1
Mean 29.4
Standard deviation 3.9
Values 27 32
[24]
HepG2.C3A PPFIA1
Mean 22.1
Standard deviation 1.5
Values 23 21
[25]
HuH.7 PPFIA1
Mean 38.2
Standard deviation 5.1
Values 38 43 33
[26]
SNU475 PPFIA1
Mean 146
Standard deviation 15
Values 1.6e+02 1.4e+02
[27]
THLE PPFIA1
Mean 33.9
Standard deviation 4
Values 31 37
[28]
liver PPFIA1
Mean 22.1
Standard deviation 4.2
Values 21 25 16 25
[29]
ref_hepatocyte UNC13B
Mean 3.23
Standard deviation 1.4
Values 2.5 5.5 2.6 3.4 2.1
[30]
HepG2 UNC13B
Mean 24.3
Standard deviation 2.4
Values 23 26
[31]
HepG2.C3A UNC13B
Mean 23.4
Standard deviation 3.3
Values 26 21
[32]
HuH.7 UNC13B
Mean 35.5
Standard deviation 5.6
Values 40 37 29
[33]
SNU475 UNC13B
Mean 7.69
Standard deviation 1.6
Values 8.8 6.5
[34]
THLE UNC13B
Mean 13
Standard deviation 0.26
Values 13 13
[35]
liver UNC13B
Mean 27.3
Standard deviation 11
Values 17 41 19 33
[36]
ref_hepatocyte RAB3A
Mean 0.786
Standard deviation 0.29
Values 0.95 0.55 0.49 0.76 1.2
[37]
HepG2 RAB3A
Mean 1.64
Standard deviation 0.46
Values 2 1.3
[38]
HepG2.C3A RAB3A
Mean 0.703
Standard deviation 0.33
Values 0.93 0.47
[39]
HuH.7 RAB3A
Mean 2.95
Standard deviation 0.48
Values 3.5 2.5 2.8
[40]
SNU475 RAB3A
Mean 0.823
Standard deviation 0.069
Values 0.77 0.87
[41]
THLE RAB3A
Mean 1.06
Standard deviation 0.15
Values 1.2 0.95
[42]
liver RAB3A
Mean 0.48
Standard deviation 0.46
Values 0.47 0.19 1.1 0.13
[43]
ref_hepatocyte SLC18A2
Mean 0.784
Standard deviation 0.93
Values 0 0 0.35 1.9 1.7
[44]
HepG2 SLC18A2
Mean 0.848
Standard deviation 0.11
Values 0.93 0.77
[45]
HepG2.C3A SLC18A2
Mean 3.83
Standard deviation 2.4
Values 5.5 2.2
[46]
HuH.7 SLC18A2
Mean 4.73
Standard deviation 0.58
Values 4.1 5.2 5
[47]
SNU475 SLC18A2
Mean 1.23
Standard deviation 0.21
Values 1.1 1.4
[48]
THLE SLC18A2
Mean 2.27
Standard deviation 1.1
Values 3 1.5
[49]
liver SLC18A2
Mean 10.9
Standard deviation 2.2
Values 14 9.4 9.1 11
[50]
ref_hepatocyte STX1A
Mean 0.672
Standard deviation 0.98
Values 0.23 0.39 2.4 0.095 0.24
[51]
HepG2 STX1A
Mean 2.85
Standard deviation 0.85
Values 3.4 2.2
[52]
HepG2.C3A STX1A
Mean 2.48
Standard deviation 0.71
Values 3 2
[53]
HuH.7 STX1A
Mean 0.845
Standard deviation 0.25
Values 0.57 0.91 1.1
[54]
SNU475 STX1A
Mean 7.45
Standard deviation 3.6
Values 4.9 10
[55]
THLE STX1A
Mean 4.19
Standard deviation 1.3
Values 5.1 3.3
[56]
liver STX1A
Mean 0.426
Standard deviation 0.18
Values 0.35 0.31 0.69 0.34
[57]
ref_hepatocyte STXBP1
Mean 0.658
Standard deviation 0.63
Values 1.7 0.64 0.69 0.22 0.065
[58]
HepG2 STXBP1
Mean 4.83
Standard deviation 0.73
Values 5.4 4.3
[59]
HepG2.C3A STXBP1
Mean 5.71
Standard deviation 0.79
Values 6.3 5.1
[60]
HuH.7 STXBP1
Mean 7.36
Standard deviation 1.4
Values 8.9 6.5 6.7
[61]
SNU475 STXBP1
Mean 22.1
Standard deviation 0.72
Values 23 22
[62]
THLE STXBP1
Mean 22.4
Standard deviation 6
Values 18 27
[63]
liver STXBP1
Mean 1.67
Standard deviation 0.8
Values 2 1.1 2.6 0.91
[64]
ref_hepatocyte CPLX1
Mean 0.58
Standard deviation 0.61
Values 0.11 0 0.34 1.1 1.4
[65]
HepG2 CPLX1
Mean 0.678
Standard deviation 0.18
Values 0.8 0.55
[66]
HepG2.C3A CPLX1
Mean 0.29
Standard deviation 0.016
Values 0.3 0.28
[67]
HuH.7 CPLX1
Mean 7.91
Standard deviation 0.96
Values 9 7.3 7.4
[68]
SNU475 CPLX1
Mean 0.143
Standard deviation 0.012
Values 0.13 0.15
[69]
THLE CPLX1
Mean 0.156
Standard deviation 0.063
Values 0.2 0.11
[70]
liver CPLX1
Mean 0.943
Standard deviation 0.4
Values 0.73 1.3 0.49 1.3
[71]
ref_hepatocyte PPFIA3
Mean 0.55
Standard deviation 0.41
Values 1.1 0 0.71 0.53 0.39
[72]
HepG2 PPFIA3
Mean 8
Standard deviation 2.9
Values 10 6
[73]
HepG2.C3A PPFIA3
Mean 9.56
Standard deviation 2.5
Values 11 7.8
[74]
HuH.7 PPFIA3
Mean 9.06
Standard deviation 0.25
Values 9.3 9 8.8
[75]
SNU475 PPFIA3
Mean 1.88
Standard deviation 0.44
Values 1.6 2.2
[76]
THLE PPFIA3
Mean 1.58
Standard deviation 0.29
Values 1.8 1.4
[77]
liver PPFIA3
Mean 0.826
Standard deviation 0.32
Values 1 0.4 1.1 0.77
[78]
ref_hepatocyte SNAP25
Mean 0.146
Standard deviation 0.17
Values 0 0 0.3 0.069 0.36
[79]
HepG2 SNAP25
Mean 0.0286
Standard deviation 0.032
Values 0.0057 0.051
[80]
HepG2.C3A SNAP25
Mean 0.0292
Standard deviation 0.041
Values 0.058 0
[81]
HuH.7 SNAP25
Mean 1.43
Standard deviation 0.14
Values 1.4 1.3 1.6
[82]
SNU475 SNAP25
Mean 1.47
Standard deviation 0.63
Values 1 1.9
[83]
THLE SNAP25
Mean 6.82
Standard deviation 0.47
Values 7.1 6.5
[84]
liver SNAP25
Mean 0.427
Standard deviation 0.11
Values 0.42 0.34 0.36 0.58
[85]
ref_hepatocyte SYT1
Mean 0.0375
Standard deviation 0.071
Values 0 0 0.16 0 0.024
[86]
HepG2 SYT1
Mean 0.0193
Standard deviation 0.021
Values 0.034 0.0043
[87]
HepG2.C3A SYT1
Mean 0.0102
Standard deviation 0.00071
Values 0.0097 0.011
[88]
HuH.7 SYT1
Mean 3.9
Standard deviation 1.6
Values 3.6 5.6 2.5
[89]
SNU475 SYT1
Mean 10
Standard deviation 0.7
Values 9.5 11
[90]
THLE SYT1
Mean 0.793
Standard deviation 0.075
Values 0.85 0.74
[91]
liver SYT1
Mean 0.992
Standard deviation 0.082
Values 0.94 1.1 0.98 0.94
[92]
ref_hepatocyte SLC22A2
Mean 0.0163
Standard deviation 0.036
Values 0 0 0.082 0 0
[93]
HepG2 SLC22A2
Mean 0
Standard deviation 0
Values 0 0
[94]
HepG2.C3A SLC22A2
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[95]
HuH.7 SLC22A2
Mean 0.00428
Standard deviation 0.0074
Values 0 0.013 0
[96]
SNU475 SLC22A2
Mean 0.0287
Standard deviation 0.012
Values 0.037 0.02
[97]
THLE SLC22A2
Mean 0.0198
Standard deviation 0.0054
Values 0.024 0.016
[98]
liver SLC22A2
Mean 0
Standard deviation 0
Values 0 0 0 0
[99]
ref_hepatocyte PPFIA2
Mean 0.00488
Standard deviation 0.011
Values 0 0 0 0 0.024
[100]
HepG2 PPFIA2
Mean 0.196
Standard deviation 0.026
Values 0.18 0.21
[101]
HepG2.C3A PPFIA2
Mean 1.33
Standard deviation 0.86
Values 1.9 0.72
[102]
HuH.7 PPFIA2
Mean 0.797
Standard deviation 0.16
Values 0.71 0.98 0.7
[103]
SNU475 PPFIA2
Mean 0.0148
Standard deviation 0.0078
Values 0.0093 0.02
[104]
THLE PPFIA2
Mean 0.0222
Standard deviation 0.0063
Values 0.018 0.027
[105]
liver PPFIA2
Mean 0.827
Standard deviation 0.62
Values 0.54 0.87 0.23 1.7
[106]
ref_hepatocyte TSPOAP1
Missing
[107]
HepG2 TSPOAP1
Missing
[108]
HepG2.C3A TSPOAP1
Missing
[109]
HuH.7 TSPOAP1
Missing
[110]
SNU475 TSPOAP1
Missing
[111]
THLE TSPOAP1
Missing
[112]
liver TSPOAP1
Missing
[113]
ref_hepatocyte RIMS1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[114]
HepG2 RIMS1
Mean 0
Standard deviation 0
Values 0 0
[115]
HepG2.C3A RIMS1
Mean 0
Standard deviation 0
Values 0 0
[116]
HuH.7 RIMS1
Mean 0
Standard deviation 0
Values 0 0 0
[117]
SNU475 RIMS1
Mean 0.0774
Standard deviation 0.002
Values 0.079 0.076
[118]
THLE RIMS1
Mean 0.0387
Standard deviation 0.013
Values 0.03 0.048
[119]
liver RIMS1
Mean 0.0607
Standard deviation 0.064
Values 0 0.071 0.026 0.15
[120]
ref_hepatocyte PPFIA4
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[121]
HepG2 PPFIA4
Mean 1.54
Standard deviation 0.4
Values 1.3 1.8
[122]
HepG2.C3A PPFIA4
Mean 1.94
Standard deviation 0.4
Values 1.7 2.2
[123]
HuH.7 PPFIA4
Mean 3.04
Standard deviation 1.1
Values 2.1 4.2 2.9
[124]
SNU475 PPFIA4
Mean 5.33
Standard deviation 1.6
Values 6.5 4.2
[125]
THLE PPFIA4
Mean 2.71
Standard deviation 1.5
Values 3.8 1.6
[126]
liver PPFIA4
Mean 0.136
Standard deviation 0.079
Values 0.19 0.2 0.13 0.026