REACTOME_NONHOMOLOGOUS_END_JOINING_NHEJ Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 XRCC6 X-ray repair cross-complementing protein 6 [1] -0.28[2] -0.86[3] -0.93[4] -1.25[5] -1.04[6] -1.51[7]
2 SUMO1 Small ubiquitin-related modifier 1 [8] -1.88[9] -1.94[10] -2.57[11] -1.86[12] -1.96[13] -1.59[14]
3 XRCC5 X-ray repair cross-complementing protein 5 [15] 0.78[16] 0.67[17] 0.28[18] 0.43[19] 0.61[20] 0.10[21]
4 BABAM1 BRISC and BRCA1-A complex member 1 [22] -1.10[23] -1.11[24] -0.48[25] -1.42[26] -0.80[27] -1.52[28]
5 TDP2 Tyrosyl-DNA phosphodiesterase 2 [29] -1.32[30] -0.31[31] -0.15[32] -0.79[33] -1.86[34] -1.64[35]
6 UBE2N Ubiquitin-conjugating enzyme E2 N [36] 0.40[37] 0.66[38] -0.78[39] -0.07[40] -0.23[41] -0.77[42]
7 UBE2V2 Ubiquitin-conjugating enzyme E2 variant 2 [43] -1.73[44] -0.94[45] -0.72[46] -0.31[47] -0.56[48] -0.65[49]
8 KAT5 Histone acetyltransferase KAT5 [50] -1.06[51] -0.87[52] -2.16[53] -1.22[54] -1.35[55] -1.12[56]
9 NBN Nibrin [57] -0.70[58] 0.26[59] -0.25[60] 1.12[61] 0.19[62] 1.22[63]
10 UIMC1 BRCA1-A complex subunit RAP80 [64] 0.09[65] 0.11[66] 0.28[67] -0.31[68] -0.21[69] -0.34[70]
11 BRCC3 Lys-63-specific deubiquitinase BRCC36 [71] -0.75[72] -0.03[73] -1.00[74] -0.61[75] -0.49[76] 0.39[77]
12 RAD50 DNA repair protein RAD50 [78] -0.13[79] 1.78[80] 0.67[81] 0.88[82] 1.32[83] 2.16[84]
13 PIAS4 E3 SUMO-protein ligase PIAS4 [85] -0.04[86] -0.74[87] -0.26[88] -0.91[89] -0.85[90] -0.46[91]
14 NHEJ1 Non-homologous end-joining factor 1 [92] 0.25[93] 0.30[94] 0.11[95] -0.46[96] -0.67[97] -0.19[98]
15 PRKDC DNA-dependent protein kinase catalytic subunit [99] 3.93[100] 3.18[101] 4.81[102] 4.50[103] 4.54[104] 4.19[105]
16 RNF8 E3 ubiquitin-protein ligase RNF8 [106] 1.06[107] 0.91[108] -0.69[109] 0.89[110] 0.33[111] -0.14[112]
17 RNF168 E3 ubiquitin-protein ligase RNF168 [113] 0.11[114] 0.54[115] 1.27[116] -0.31[117] 0.80[118] 2.04[119]
18 POLL DNA polymerase lambda [120] 0.71[121] 1.44[122] 1.74[123] -0.34[124] 0.20[125] 0.19[126]
19 LIG4 DNA ligase 4 [127] -1.49[128] 0.21[129] -1.17[130] 0.39[131] 0.15[132] 1.44[133]
20 PAXIP1 PAX-interacting protein 1 [134] 0.67[135] 0.51[136] 0.73[137] 0.16[138] 0.28[139] 0.24[140]
21 MDC1 Mediator of DNA damage checkpoint protein 1 [141] 2.20[142] 2.39[143] 2.47[144] 2.51[145] 2.38[146] 1.40[147]
22 XRCC4 DNA repair protein XRCC4 [148] -0.87[149] 0.51[150] 0.03[151] -0.19[152] -0.26[153] -0.80[154]
23 BRCA1 Breast cancer type 1 susceptibility protein [155] 1.39[156] 2.42[157] 2.55[158] 1.76[159] 2.23[160] 1.63[161]
24 POLM DNA-directed DNA/RNA polymerase mu [162] -0.59[163] -0.42[164] 0.11[165] -0.21[166] -0.51[167] 1.15[168]
25 HERC2 E3 ubiquitin-protein ligase HERC2 [169] 2.17[170] 1.65[171] 1.95[172] 2.70[173] 2.72[174] 4.12[175]
26 RIF1 Telomere-associated protein RIF1 [176] 1.23[177] 3.15[178] 2.04[179] 2.52[180] 2.91[181] 3.50[182]
27 TDP1 Tyrosyl-DNA phosphodiesterase 1 [183] 1.29[184] 1.19[185] 0.68[186] 1.51[187] 1.01[188] 0.37[189]
28 TP53BP1 TP53-binding protein 1 [190] 2.30[191] 1.59[192] 2.29[193] 3.55[194] 2.96[195] 2.23[196]
29 ATM Serine-protein kinase ATM [197] 2.75[198] 4.13[199] 3.60[200] 3.77[201] 3.20[202] 4.94[203]
30 DCLRE1C Protein artemis [204] -0.01[205] 1.28[206] 0.17[207] 2.26[208] 1.01[209] 1.41[210]
31 BARD1 BRCA1-associated RING domain protein 1 [211] 1.03[212] 1.80[213] 1.56[214] 2.31[215] 2.35[216] 1.82[217]
32 H2BC11 [218] [219] [220] [221] [222] [223] [224]
33 H2BC12 [225] [226] [227] [228] [229] [230] [231]
34 H2BC13 [232] [233] [234] [235] [236] [237] [238]
35 H4C2 [239] [240] [241] [242] [243] [244] [245]
36 H4C1 [246] [247] [248] [249] [250] [251] [252]
37 H4C15 [253] [254] [255] [256] [257] [258] [259]
38 H2BC14 [260] [261] [262] [263] [264] [265] [266]
39 H2BC8 [267] [268] [269] [270] [271] [272] [273]
40 H2BC5 [274] [275] [276] [277] [278] [279] [280]
41 H4C6 [281] [282] [283] [284] [285] [286] [287]
42 H4C14 [288] [289] [290] [291] [292] [293] [294]
43 H2BC17 [295] [296] [297] [298] [299] [300] [301]
44 H2BC21 [302] [303] [304] [305] [306] [307] [308]
45 ABRAXAS1 BRCA1-A complex subunit Abraxas 1 [309] [310] [311] [312] [313] [314] [315]
46 NSD2 Histone-lysine N-methyltransferase NSD2 [316] [317] [318] [319] [320] [321] [322]
47 MRE11 Double-strand break repair protein MRE11 [323] [324] [325] [326] [327] [328] [329]
48 H2BC4 [330] [331] [332] [333] [334] [335] [336]
49 H2AX [337] [338] [339] [340] [341] [342] [343]
50 H2BU1 [344] [345] [346] [347] [348] [349] [350]
51 H2BC6 [351] [352] [353] [354] [355] [356] [357]
52 H2BC10 [358] [359] [360] [361] [362] [363] [364]
53 H2BC1 [365] [366] [367] [368] [369] [370] [371]
54 H4C8 [372] [373] [374] [375] [376] [377] [378]
55 H4C5 [379] [380] [381] [382] [383] [384] [385]
56 H3-4 [386] [387] [388] [389] [390] [391] [392]
57 H2BC15 [393] [394] [395] [396] [397] [398] [399]
58 H4C4 [400] [401] [402] [403] [404] [405] [406]
59 H4C11 [407] [408] [409] [410] [411] [412] [413]
60 H4C13 [414] [415] [416] [417] [418] [419] [420]
61 H2BC9 [421] [422] [423] [424] [425] [426] [427]
62 H2BC7 [428] [429] [430] [431] [432] [433] [434]
63 H4-16 [435] [436] [437] [438] [439] [440] [441]
64 H2BC3 [442] [443] [444] [445] [446] [447] [448]
65 BABAM2 BRISC and BRCA1-A complex member 2 [449] [450] [451] [452] [453] [454] [455]
66 H4C3 [456] [457] [458] [459] [460] [461] [462]
67 H4C9 [463] [464] [465] [466] [467] [468] [469]
68 H2BS1 [470] [471] [472] [473] [474] [475] [476]
69 H4C12 [477] [478] [479] [480] [481] [482] [483]
[1]
ref_hepatocyte XRCC6
Mean 131
Standard deviation 74
Values 1.7e+02 2.4e+02 1.2e+02 73 58
[2]
HepG2 XRCC6
Mean 289
Standard deviation 39
Values 2.6e+02 3.2e+02
[3]
HepG2.C3A XRCC6
Mean 200
Standard deviation 42
Values 1.7e+02 2.3e+02
[4]
HuH.7 XRCC6
Mean 220
Standard deviation 54
Values 2.6e+02 1.6e+02 2.4e+02
[5]
SNU475 XRCC6
Mean 132
Standard deviation 1.1
Values 1.3e+02 1.3e+02
[6]
THLE XRCC6
Mean 176
Standard deviation 61
Values 1.3e+02 2.2e+02
[7]
liver XRCC6
Mean 67.3
Standard deviation 21
Values 80 58 89 42
[8]
ref_hepatocyte SUMO1
Mean 76.3
Standard deviation 10
Values 80 74 89 61 77
[9]
HepG2 SUMO1
Mean 55.7
Standard deviation 4.2
Values 53 59
[10]
HepG2.C3A SUMO1
Mean 55.2
Standard deviation 14
Values 45 65
[11]
HuH.7 SUMO1
Mean 41.2
Standard deviation 13
Values 44 27 53
[12]
SNU475 SUMO1
Mean 50.5
Standard deviation 16
Values 62 40
[13]
THLE SUMO1
Mean 54.6
Standard deviation 7.9
Values 49 60
[14]
liver SUMO1
Mean 37.2
Standard deviation 30
Values 71 13 54 10
[15]
ref_hepatocyte XRCC5
Mean 49.2
Standard deviation 25
Values 80 72 28 35 31
[16]
HepG2 XRCC5
Mean 227
Standard deviation 47
Values 1.9e+02 2.6e+02
[17]
HepG2.C3A XRCC5
Mean 218
Standard deviation 87
Values 1.6e+02 2.8e+02
[18]
HuH.7 XRCC5
Mean 192
Standard deviation 57
Values 2.4e+02 1.3e+02 2.1e+02
[19]
SNU475 XRCC5
Mean 160
Standard deviation 1.4
Values 1.6e+02 1.6e+02
[20]
THLE XRCC5
Mean 209
Standard deviation 38
Values 1.8e+02 2.4e+02
[21]
liver XRCC5
Mean 77.5
Standard deviation 10
Values 78 81 87 63
[22]
ref_hepatocyte BABAM1
Mean 25.1
Standard deviation 11
Values 9.1 20 38 31 27
[23]
HepG2 BABAM1
Mean 31.4
Standard deviation 1.1
Values 32 31
[24]
HepG2.C3A BABAM1
Mean 32.3
Standard deviation 3.5
Values 30 35
[25]
HuH.7 BABAM1
Mean 57.5
Standard deviation 17
Values 60 39 73
[26]
SNU475 BABAM1
Mean 22.6
Standard deviation 4.4
Values 26 19
[27]
THLE BABAM1
Mean 40.2
Standard deviation 2.6
Values 38 42
[28]
liver BABAM1
Mean 12.9
Standard deviation 5.9
Values 17 8.3 19 7.2
[29]
ref_hepatocyte TDP2
Mean 22.2
Standard deviation 7.2
Values 28 30 13 18 21
[30]
HepG2 TDP2
Mean 23.9
Standard deviation 7.3
Values 19 29
[31]
HepG2.C3A TDP2
Mean 49.8
Standard deviation 17
Values 37 62
[32]
HuH.7 TDP2
Mean 64.3
Standard deviation 16
Values 49 82 62
[33]
SNU475 TDP2
Mean 30.7
Standard deviation 2.2
Values 32 29
[34]
THLE TDP2
Mean 17
Standard deviation 0.95
Values 16 18
[35]
liver TDP2
Mean 10.4
Standard deviation 3.8
Values 15 8.4 12 6.2
[36]
ref_hepatocyte UBE2N
Mean 19.2
Standard deviation 7.8
Values 19 28 25 11 12
[37]
HepG2 UBE2N
Mean 68.4
Standard deviation 19
Values 55 82
[38]
HepG2.C3A UBE2N
Mean 84.8
Standard deviation 36
Values 60 1.1e+02
[39]
HuH.7 UBE2N
Mean 36
Standard deviation 8.3
Values 38 27 43
[40]
SNU475 UBE2N
Mean 44
Standard deviation 3.7
Values 47 41
[41]
THLE UBE2N
Mean 45.7
Standard deviation 8
Values 40 51
[42]
liver UBE2N
Mean 16.6
Standard deviation 11
Values 25 8.3 27 5.9
[43]
ref_hepatocyte UBE2V2
Mean 17.6
Standard deviation 6.9
Values 20 28 11 13 15
[44]
HepG2 UBE2V2
Mean 14.2
Standard deviation 2.4
Values 12 16
[45]
HepG2.C3A UBE2V2
Mean 25.5
Standard deviation 7.5
Values 20 31
[46]
HuH.7 UBE2V2
Mean 34
Standard deviation 6
Values 36 27 39
[47]
SNU475 UBE2V2
Mean 34
Standard deviation 0.83
Values 35 33
[48]
THLE UBE2V2
Mean 33
Standard deviation 0.8
Values 34 32
[49]
liver UBE2V2
Mean 16.4
Standard deviation 14
Values 25 5.8 31 3.8
[50]
ref_hepatocyte KAT5
Mean 6.92
Standard deviation 2.7
Values 6 6.4 12 6.3 4.4
[51]
HepG2 KAT5
Mean 8.9
Standard deviation 0.12
Values 9 8.8
[52]
HepG2.C3A KAT5
Mean 10.6
Standard deviation 0.63
Values 11 10
[53]
HuH.7 KAT5
Mean 4.96
Standard deviation 0.22
Values 4.9 4.8 5.2
[54]
SNU475 KAT5
Mean 7.11
Standard deviation 0.33
Values 6.9 7.3
[55]
THLE KAT5
Mean 7.53
Standard deviation 0.42
Values 7.2 7.8
[56]
liver KAT5
Mean 4.69
Standard deviation 1
Values 5.5 4.1 5.7 3.5
[57]
ref_hepatocyte NBN
Mean 5.99
Standard deviation 3.6
Values 7.6 11 3.9 2.7 4.3
[58]
HepG2 NBN
Mean 9.9
Standard deviation 6.3
Values 5.4 14
[59]
HepG2.C3A NBN
Mean 20
Standard deviation 9.1
Values 14 26
[60]
HuH.7 NBN
Mean 16.2
Standard deviation 4.2
Values 20 12 17
[61]
SNU475 NBN
Mean 31.2
Standard deviation 0.96
Values 30 32
[62]
THLE NBN
Mean 19
Standard deviation 0.88
Values 20 18
[63]
liver NBN
Mean 20.5
Standard deviation 4.2
Values 19 24 24 16
[64]
ref_hepatocyte UIMC1
Mean 5.15
Standard deviation 4.3
Values 3.4 4.5 13 3.3 2
[65]
HepG2 UIMC1
Mean 14.7
Standard deviation 0.61
Values 14 15
[66]
HepG2.C3A UIMC1
Mean 15.4
Standard deviation 0.39
Values 16 15
[67]
HuH.7 UIMC1
Mean 20.1
Standard deviation 1.6
Values 19 19 22
[68]
SNU475 UIMC1
Mean 9.94
Standard deviation 0.92
Values 9.3 11
[69]
THLE UIMC1
Mean 12.4
Standard deviation 0.38
Values 12 13
[70]
liver UIMC1
Mean 5.96
Standard deviation 1.3
Values 4.6 7.7 5.5 6
[71]
ref_hepatocyte BRCC3
Mean 5.02
Standard deviation 2.2
Values 7.3 7.5 3.1 3.2 4
[72]
HepG2 BRCC3
Mean 8.01
Standard deviation 4.4
Values 4.9 11
[73]
HepG2.C3A BRCC3
Mean 13.7
Standard deviation 6.4
Values 9.1 18
[74]
HuH.7 BRCC3
Mean 8.03
Standard deviation 1.6
Values 9.4 6.3 8.3
[75]
SNU475 BRCC3
Mean 7.86
Standard deviation 0.18
Values 7.7 8
[76]
THLE BRCC3
Mean 9.91
Standard deviation 0.42
Values 10 9.6
[77]
liver BRCC3
Mean 9.64
Standard deviation 3.8
Values 12 7.8 13 5.2
[78]
ref_hepatocyte RAD50
Mean 3.85
Standard deviation 2.1
Values 3.9 7.4 2.3 2.9 2.8
[79]
HepG2 RAD50
Mean 9.45
Standard deviation 2.3
Values 7.9 11
[80]
HepG2.C3A RAD50
Mean 36.9
Standard deviation 0.99
Values 38 36
[81]
HuH.7 RAD50
Mean 19.7
Standard deviation 4.1
Values 22 22 15
[82]
SNU475 RAD50
Mean 17
Standard deviation 2.2
Values 15 19
[83]
THLE RAD50
Mean 26.8
Standard deviation 8.4
Values 33 21
[84]
liver RAD50
Mean 25.2
Standard deviation 5.7
Values 32 26 25 18
[85]
ref_hepatocyte PIAS4
Mean 3.53
Standard deviation 1
Values 4.5 2.7 3.6 4.6 2.3
[86]
HepG2 PIAS4
Mean 9.22
Standard deviation 1.8
Values 10 8
[87]
HepG2.C3A PIAS4
Mean 5.88
Standard deviation 0.98
Values 6.6 5.2
[88]
HuH.7 PIAS4
Mean 9.46
Standard deviation 0.82
Values 10 8.9 9.1
[89]
SNU475 PIAS4
Mean 4.49
Standard deviation 0.4
Values 4.2 4.8
[90]
THLE PIAS4
Mean 5.43
Standard deviation 0.61
Values 5 5.9
[91]
liver PIAS4
Mean 3.76
Standard deviation 0.52
Values 4.1 3.9 3 4.1
[92]
ref_hepatocyte NHEJ1
Mean 3.52
Standard deviation 0.96
Values 4.3 2.3 2.7 3.9 4.5
[93]
HepG2 NHEJ1
Mean 11.2
Standard deviation 1.4
Values 10 12
[94]
HepG2.C3A NHEJ1
Mean 12
Standard deviation 2.5
Values 14 10
[95]
HuH.7 NHEJ1
Mean 12.2
Standard deviation 0.32
Values 12 12 13
[96]
SNU475 NHEJ1
Mean 6.12
Standard deviation 0.7
Values 5.6 6.6
[97]
THLE NHEJ1
Mean 6.15
Standard deviation 0.94
Values 5.5 6.8
[98]
liver NHEJ1
Mean 4.53
Standard deviation 1.1
Values 5.8 3.4 5.1 3.8
[99]
ref_hepatocyte PRKDC
Mean 3.34
Standard deviation 1.6
Values 5.3 5 1.9 2.2 2.4
[100]
HepG2 PRKDC
Mean 137
Standard deviation 25
Values 1.2e+02 1.5e+02
[101]
HepG2.C3A PRKDC
Mean 84.1
Standard deviation 23
Values 68 1e+02
[102]
HuH.7 PRKDC
Mean 299
Standard deviation 1.8e+02
Values 5e+02 1.6e+02 2.4e+02
[103]
SNU475 PRKDC
Mean 182
Standard deviation 16
Values 1.7e+02 1.9e+02
[104]
THLE PRKDC
Mean 216
Standard deviation 37
Values 1.9e+02 2.4e+02
[105]
liver PRKDC
Mean 89.5
Standard deviation 54
Values 43 1.5e+02 47 1.1e+02
[106]
ref_hepatocyte RNF8
Mean 3.22
Standard deviation 2.5
Values 6.9 4.6 2.2 1.5 1
[107]
HepG2 RNF8
Mean 18
Standard deviation 2.4
Values 16 20
[108]
HepG2.C3A RNF8
Mean 16.9
Standard deviation 0.047
Values 17 17
[109]
HuH.7 RNF8
Mean 6.38
Standard deviation 0.46
Values 5.8 6.7 6.6
[110]
SNU475 RNF8
Mean 14.3
Standard deviation 0.79
Values 14 15
[111]
THLE RNF8
Mean 11.2
Standard deviation 0.72
Values 11 12
[112]
liver RNF8
Mean 4.3
Standard deviation 0.98
Values 5.5 3.9 4.6 3.2
[113]
ref_hepatocyte RNF168
Mean 2.39
Standard deviation 0.84
Values 3.1 3.1 2.7 1.2 1.8
[114]
HepG2 RNF168
Mean 6.93
Standard deviation 1.4
Values 5.9 7.9
[115]
HepG2.C3A RNF168
Mean 9.67
Standard deviation 0.69
Values 10 9.2
[116]
HuH.7 RNF168
Mean 18.4
Standard deviation 3.1
Values 22 18 16
[117]
SNU475 RNF168
Mean 4.63
Standard deviation 0.52
Values 4.3 5
[118]
THLE RNF168
Mean 11.6
Standard deviation 0.93
Values 11 12
[119]
liver RNF168
Mean 14.5
Standard deviation 2.9
Values 15 13 18 11
[120]
ref_hepatocyte POLL
Mean 2.39
Standard deviation 1.5
Values 0.67 1.4 2.3 3 4.5
[121]
HepG2 POLL
Mean 10.5
Standard deviation 3
Values 13 8.4
[122]
HepG2.C3A POLL
Mean 18.1
Standard deviation 6.6
Values 23 13
[123]
HuH.7 POLL
Mean 25.5
Standard deviation 0.64
Values 25 26 26
[124]
SNU475 POLL
Mean 4.53
Standard deviation 0.3
Values 4.7 4.3
[125]
THLE POLL
Mean 7.64
Standard deviation 0.2
Values 7.5 7.8
[126]
liver POLL
Mean 4
Standard deviation 1.5
Values 6 2.5 4.4 3.1
[127]
ref_hepatocyte LIG4
Mean 2.34
Standard deviation 2.7
Values 1.1 7.2 0.77 1.2 1.4
[128]
HepG2 LIG4
Mean 2.23
Standard deviation 0.57
Values 1.8 2.6
[129]
HepG2.C3A LIG4
Mean 7.5
Standard deviation 2.4
Values 9.2 5.8
[130]
HuH.7 LIG4
Mean 3.33
Standard deviation 0.78
Values 2.8 4.2 2.9
[131]
SNU475 LIG4
Mean 7.33
Standard deviation 1.1
Values 6.6 8.1
[132]
THLE LIG4
Mean 7.2
Standard deviation 1
Values 7.9 6.5
[133]
liver LIG4
Mean 9.32
Standard deviation 2.7
Values 8.1 13 8.1 7.7
[134]
ref_hepatocyte PAXIP1
Mean 2.13
Standard deviation 1.1
Values 2.5 1.3 3.8 1.7 1.3
[135]
HepG2 PAXIP1
Mean 9.07
Standard deviation 1.8
Values 7.8 10
[136]
HepG2.C3A PAXIP1
Mean 8.44
Standard deviation 2
Values 7 9.9
[137]
HuH.7 PAXIP1
Mean 11.3
Standard deviation 1.7
Values 13 9.6 11
[138]
SNU475 PAXIP1
Mean 5.69
Standard deviation 0.49
Values 6 5.3
[139]
THLE PAXIP1
Mean 7.18
Standard deviation 0.93
Values 6.5 7.8
[140]
liver PAXIP1
Mean 3.68
Standard deviation 1.2
Values 2.9 4.8 2.5 4.5
[141]
ref_hepatocyte MDC1
Mean 2.03
Standard deviation 1.1
Values 3.5 1.6 2.9 1.1 1.1
[142]
HepG2 MDC1
Mean 25.1
Standard deviation 0.18
Values 25 25
[143]
HepG2.C3A MDC1
Mean 29.6
Standard deviation 2.6
Values 28 31
[144]
HuH.7 MDC1
Mean 35.9
Standard deviation 14
Values 51 23 34
[145]
SNU475 MDC1
Mean 27.7
Standard deviation 2.6
Values 26 30
[146]
THLE MDC1
Mean 29.5
Standard deviation 7.6
Values 24 35
[147]
liver MDC1
Mean 7.87
Standard deviation 1.2
Values 7.8 6.3 8.2 9.1
[148]
ref_hepatocyte XRCC4
Mean 1.95
Standard deviation 0.62
Values 2.8 1.4 1.3 2 2.3
[149]
HepG2 XRCC4
Mean 2.86
Standard deviation 0.8
Values 2.3 3.4
[150]
HepG2.C3A XRCC4
Mean 7.71
Standard deviation 4.4
Values 4.6 11
[151]
HuH.7 XRCC4
Mean 6.38
Standard deviation 0.78
Values 6.3 5.6 7.2
[152]
SNU475 XRCC4
Mean 4.1
Standard deviation 0.37
Values 3.8 4.4
[153]
THLE XRCC4
Mean 4.53
Standard deviation 0.45
Values 4.2 4.9
[154]
liver XRCC4
Mean 1.65
Standard deviation 0.81
Values 1.8 1.4 2.7 0.77
[155]
ref_hepatocyte BRCA1
Mean 1.87
Standard deviation 0.88
Values 2.7 1.4 0.59 2.6 2
[156]
HepG2 BRCA1
Mean 13.1
Standard deviation 3
Values 11 15
[157]
HepG2.C3A BRCA1
Mean 27.8
Standard deviation 18
Values 15 40
[158]
HuH.7 BRCA1
Mean 35
Standard deviation 16
Values 49 17 39
[159]
SNU475 BRCA1
Mean 15.2
Standard deviation 6.4
Values 11 20
[160]
THLE BRCA1
Mean 24.5
Standard deviation 0.48
Values 25 24
[161]
liver BRCA1
Mean 8.47
Standard deviation 9.4
Values 22 4.3 2.5 4.5
[162]
ref_hepatocyte POLM
Mean 1.79
Standard deviation 0.97
Values 0.45 1.1 2.6 2.5 2.4
[163]
HepG2 POLM
Mean 3.22
Standard deviation 0.4
Values 3.5 2.9
[164]
HepG2.C3A POLM
Mean 3.73
Standard deviation 1.6
Values 4.8 2.6
[165]
HuH.7 POLM
Mean 6.19
Standard deviation 0.43
Values 6.5 5.7 6.3
[166]
SNU475 POLM
Mean 3.72
Standard deviation 0.23
Values 3.6 3.9
[167]
THLE POLM
Mean 3.5
Standard deviation 0.15
Values 3.4 3.6
[168]
liver POLM
Mean 5.84
Standard deviation 1.2
Values 7.1 5.1 6.5 4.6
[169]
ref_hepatocyte HERC2
Mean 1.73
Standard deviation 0.74
Values 2.1 2.7 0.75 1.6 1.5
[170]
HepG2 HERC2
Mean 20.9
Standard deviation 3.4
Values 19 23
[171]
HepG2.C3A HERC2
Mean 15.1
Standard deviation 0.69
Values 15 16
[172]
HuH.7 HERC2
Mean 21.3
Standard deviation 6.2
Values 28 19 17
[173]
SNU475 HERC2
Mean 26.9
Standard deviation 2.6
Values 29 25
[174]
THLE HERC2
Mean 31.7
Standard deviation 7.8
Values 26 37
[175]
liver HERC2
Mean 44
Standard deviation 30
Values 20 72 17 68
[176]
ref_hepatocyte RIF1
Mean 1.73
Standard deviation 1
Values 3.2 1.8 2 0.51 1.1
[177]
HepG2 RIF1
Mean 10.9
Standard deviation 4.6
Values 7.6 14
[178]
HepG2.C3A RIF1
Mean 42.7
Standard deviation 22
Values 27 58
[179]
HuH.7 RIF1
Mean 22.7
Standard deviation 6.9
Values 30 21 17
[180]
SNU475 RIF1
Mean 23.8
Standard deviation 5.1
Values 20 27
[181]
THLE RIF1
Mean 36.2
Standard deviation 12
Values 45 28
[182]
liver RIF1
Mean 28.7
Standard deviation 9.9
Values 23 42 20 31
[183]
ref_hepatocyte TDP1
Mean 1.53
Standard deviation 0.64
Values 1.7 1.7 2.5 0.95 0.89
[184]
HepG2 TDP1
Mean 10.1
Standard deviation 2.4
Values 8.4 12
[185]
HepG2.C3A TDP1
Mean 9.75
Standard deviation 2.6
Values 7.9 12
[186]
HuH.7 TDP1
Mean 7.85
Standard deviation 2.7
Values 9.5 4.7 9.3
[187]
SNU475 TDP1
Mean 10.5
Standard deviation 1
Values 11 9.8
[188]
THLE TDP1
Mean 8.61
Standard deviation 0.7
Values 8.1 9.1
[189]
liver TDP1
Mean 2.9
Standard deviation 0.65
Values 3.1 2.8 3.6 2.1
[190]
ref_hepatocyte TP53BP1
Mean 1.45
Standard deviation 0.79
Values 2.6 1.9 0.55 1.2 1.1
[191]
HepG2 TP53BP1
Mean 19.2
Standard deviation 4.3
Values 16 22
[192]
HepG2.C3A TP53BP1
Mean 12.2
Standard deviation 0.33
Values 12 12
[193]
HuH.7 TP53BP1
Mean 22.8
Standard deviation 5.7
Values 29 19 20
[194]
SNU475 TP53BP1
Mean 40.8
Standard deviation 4
Values 44 38
[195]
THLE TP53BP1
Mean 31.4
Standard deviation 1.4
Values 30 32
[196]
liver TP53BP1
Mean 10
Standard deviation 6
Values 4.5 19 8 9.1
[197]
ref_hepatocyte ATM
Mean 0.969
Standard deviation 0.7
Values 2.1 0.69 0.27 0.7 1.1
[198]
HepG2 ATM
Mean 17.5
Standard deviation 8.3
Values 12 23
[199]
HepG2.C3A ATM
Mean 47.4
Standard deviation 4.5
Values 44 51
[200]
HuH.7 ATM
Mean 37.5
Standard deviation 9.1
Values 41 44 27
[201]
SNU475 ATM
Mean 31.7
Standard deviation 8.2
Values 38 26
[202]
THLE ATM
Mean 24.9
Standard deviation 4.4
Values 28 22
[203]
liver ATM
Mean 43.7
Standard deviation 31
Values 17 76 17 64
[204]
ref_hepatocyte DCLRE1C
Mean 0.915
Standard deviation 0.82
Values 1.3 0.43 2.2 0.35 0.29
[205]
HepG2 DCLRE1C
Mean 2.44
Standard deviation 0.83
Values 1.9 3
[206]
HepG2.C3A DCLRE1C
Mean 6.16
Standard deviation 2.6
Values 4.3 8
[207]
HuH.7 DCLRE1C
Mean 3.29
Standard deviation 0.62
Values 4 3.1 2.8
[208]
SNU475 DCLRE1C
Mean 10.5
Standard deviation 1
Values 9.7 11
[209]
THLE DCLRE1C
Mean 5.11
Standard deviation 0.00028
Values 5.1 5.1
[210]
liver DCLRE1C
Mean 3.57
Standard deviation 0.72
Values 4 3.3 4.3 2.7
[211]
ref_hepatocyte BARD1
Mean 0.427
Standard deviation 0.62
Values 0.59 1.4 0 0.1 0
[212]
HepG2 BARD1
Mean 2.35
Standard deviation 1.5
Values 1.3 3.4
[213]
HepG2.C3A BARD1
Mean 4.15
Standard deviation 3.3
Values 1.8 6.4
[214]
HuH.7 BARD1
Mean 4.04
Standard deviation 1.6
Values 5.9 3 3.3
[215]
SNU475 BARD1
Mean 5.09
Standard deviation 0.31
Values 4.9 5.3
[216]
THLE BARD1
Mean 6.04
Standard deviation 1.7
Values 4.8 7.3
[217]
liver BARD1
Mean 2.22
Standard deviation 0.7
Values 1.4 3 1.9 2.5
[218]
ref_hepatocyte H2BC11
Missing
[219]
HepG2 H2BC11
Missing
[220]
HepG2.C3A H2BC11
Missing
[221]
HuH.7 H2BC11
Missing
[222]
SNU475 H2BC11
Missing
[223]
THLE H2BC11
Missing
[224]
liver H2BC11
Missing
[225]
ref_hepatocyte H2BC12
Missing
[226]
HepG2 H2BC12
Missing
[227]
HepG2.C3A H2BC12
Missing
[228]
HuH.7 H2BC12
Missing
[229]
SNU475 H2BC12
Missing
[230]
THLE H2BC12
Missing
[231]
liver H2BC12
Missing
[232]
ref_hepatocyte H2BC13
Missing
[233]
HepG2 H2BC13
Missing
[234]
HepG2.C3A H2BC13
Missing
[235]
HuH.7 H2BC13
Missing
[236]
SNU475 H2BC13
Missing
[237]
THLE H2BC13
Missing
[238]
liver H2BC13
Missing
[239]
ref_hepatocyte H4C2
Missing
[240]
HepG2 H4C2
Missing
[241]
HepG2.C3A H4C2
Missing
[242]
HuH.7 H4C2
Missing
[243]
SNU475 H4C2
Missing
[244]
THLE H4C2
Missing
[245]
liver H4C2
Missing
[246]
ref_hepatocyte H4C1
Missing
[247]
HepG2 H4C1
Missing
[248]
HepG2.C3A H4C1
Missing
[249]
HuH.7 H4C1
Missing
[250]
SNU475 H4C1
Missing
[251]
THLE H4C1
Missing
[252]
liver H4C1
Missing
[253]
ref_hepatocyte H4C15
Missing
[254]
HepG2 H4C15
Missing
[255]
HepG2.C3A H4C15
Missing
[256]
HuH.7 H4C15
Missing
[257]
SNU475 H4C15
Missing
[258]
THLE H4C15
Missing
[259]
liver H4C15
Missing
[260]
ref_hepatocyte H2BC14
Missing
[261]
HepG2 H2BC14
Missing
[262]
HepG2.C3A H2BC14
Missing
[263]
HuH.7 H2BC14
Missing
[264]
SNU475 H2BC14
Missing
[265]
THLE H2BC14
Missing
[266]
liver H2BC14
Missing
[267]
ref_hepatocyte H2BC8
Missing
[268]
HepG2 H2BC8
Missing
[269]
HepG2.C3A H2BC8
Missing
[270]
HuH.7 H2BC8
Missing
[271]
SNU475 H2BC8
Missing
[272]
THLE H2BC8
Missing
[273]
liver H2BC8
Missing
[274]
ref_hepatocyte H2BC5
Missing
[275]
HepG2 H2BC5
Missing
[276]
HepG2.C3A H2BC5
Missing
[277]
HuH.7 H2BC5
Missing
[278]
SNU475 H2BC5
Missing
[279]
THLE H2BC5
Missing
[280]
liver H2BC5
Missing
[281]
ref_hepatocyte H4C6
Missing
[282]
HepG2 H4C6
Missing
[283]
HepG2.C3A H4C6
Missing
[284]
HuH.7 H4C6
Missing
[285]
SNU475 H4C6
Missing
[286]
THLE H4C6
Missing
[287]
liver H4C6
Missing
[288]
ref_hepatocyte H4C14
Missing
[289]
HepG2 H4C14
Missing
[290]
HepG2.C3A H4C14
Missing
[291]
HuH.7 H4C14
Missing
[292]
SNU475 H4C14
Missing
[293]
THLE H4C14
Missing
[294]
liver H4C14
Missing
[295]
ref_hepatocyte H2BC17
Missing
[296]
HepG2 H2BC17
Missing
[297]
HepG2.C3A H2BC17
Missing
[298]
HuH.7 H2BC17
Missing
[299]
SNU475 H2BC17
Missing
[300]
THLE H2BC17
Missing
[301]
liver H2BC17
Missing
[302]
ref_hepatocyte H2BC21
Missing
[303]
HepG2 H2BC21
Missing
[304]
HepG2.C3A H2BC21
Missing
[305]
HuH.7 H2BC21
Missing
[306]
SNU475 H2BC21
Missing
[307]
THLE H2BC21
Missing
[308]
liver H2BC21
Missing
[309]
ref_hepatocyte ABRAXAS1
Missing
[310]
HepG2 ABRAXAS1
Missing
[311]
HepG2.C3A ABRAXAS1
Missing
[312]
HuH.7 ABRAXAS1
Missing
[313]
SNU475 ABRAXAS1
Missing
[314]
THLE ABRAXAS1
Missing
[315]
liver ABRAXAS1
Missing
[316]
ref_hepatocyte NSD2
Missing
[317]
HepG2 NSD2
Missing
[318]
HepG2.C3A NSD2
Missing
[319]
HuH.7 NSD2
Missing
[320]
SNU475 NSD2
Missing
[321]
THLE NSD2
Missing
[322]
liver NSD2
Missing
[323]
ref_hepatocyte MRE11
Missing
[324]
HepG2 MRE11
Missing
[325]
HepG2.C3A MRE11
Missing
[326]
HuH.7 MRE11
Missing
[327]
SNU475 MRE11
Missing
[328]
THLE MRE11
Missing
[329]
liver MRE11
Missing
[330]
ref_hepatocyte H2BC4
Missing
[331]
HepG2 H2BC4
Missing
[332]
HepG2.C3A H2BC4
Missing
[333]
HuH.7 H2BC4
Missing
[334]
SNU475 H2BC4
Missing
[335]
THLE H2BC4
Missing
[336]
liver H2BC4
Missing
[337]
ref_hepatocyte H2AX
Missing
[338]
HepG2 H2AX
Missing
[339]
HepG2.C3A H2AX
Missing
[340]
HuH.7 H2AX
Missing
[341]
SNU475 H2AX
Missing
[342]
THLE H2AX
Missing
[343]
liver H2AX
Missing
[344]
ref_hepatocyte H2BU1
Missing
[345]
HepG2 H2BU1
Missing
[346]
HepG2.C3A H2BU1
Missing
[347]
HuH.7 H2BU1
Missing
[348]
SNU475 H2BU1
Missing
[349]
THLE H2BU1
Missing
[350]
liver H2BU1
Missing
[351]
ref_hepatocyte H2BC6
Missing
[352]
HepG2 H2BC6
Missing
[353]
HepG2.C3A H2BC6
Missing
[354]
HuH.7 H2BC6
Missing
[355]
SNU475 H2BC6
Missing
[356]
THLE H2BC6
Missing
[357]
liver H2BC6
Missing
[358]
ref_hepatocyte H2BC10
Missing
[359]
HepG2 H2BC10
Missing
[360]
HepG2.C3A H2BC10
Missing
[361]
HuH.7 H2BC10
Missing
[362]
SNU475 H2BC10
Missing
[363]
THLE H2BC10
Missing
[364]
liver H2BC10
Missing
[365]
ref_hepatocyte H2BC1
Missing
[366]
HepG2 H2BC1
Missing
[367]
HepG2.C3A H2BC1
Missing
[368]
HuH.7 H2BC1
Missing
[369]
SNU475 H2BC1
Missing
[370]
THLE H2BC1
Missing
[371]
liver H2BC1
Missing
[372]
ref_hepatocyte H4C8
Missing
[373]
HepG2 H4C8
Missing
[374]
HepG2.C3A H4C8
Missing
[375]
HuH.7 H4C8
Missing
[376]
SNU475 H4C8
Missing
[377]
THLE H4C8
Missing
[378]
liver H4C8
Missing
[379]
ref_hepatocyte H4C5
Missing
[380]
HepG2 H4C5
Missing
[381]
HepG2.C3A H4C5
Missing
[382]
HuH.7 H4C5
Missing
[383]
SNU475 H4C5
Missing
[384]
THLE H4C5
Missing
[385]
liver H4C5
Missing
[386]
ref_hepatocyte H3-4
Missing
[387]
HepG2 H3-4
Missing
[388]
HepG2.C3A H3-4
Missing
[389]
HuH.7 H3-4
Missing
[390]
SNU475 H3-4
Missing
[391]
THLE H3-4
Missing
[392]
liver H3-4
Missing
[393]
ref_hepatocyte H2BC15
Missing
[394]
HepG2 H2BC15
Missing
[395]
HepG2.C3A H2BC15
Missing
[396]
HuH.7 H2BC15
Missing
[397]
SNU475 H2BC15
Missing
[398]
THLE H2BC15
Missing
[399]
liver H2BC15
Missing
[400]
ref_hepatocyte H4C4
Missing
[401]
HepG2 H4C4
Missing
[402]
HepG2.C3A H4C4
Missing
[403]
HuH.7 H4C4
Missing
[404]
SNU475 H4C4
Missing
[405]
THLE H4C4
Missing
[406]
liver H4C4
Missing
[407]
ref_hepatocyte H4C11
Missing
[408]
HepG2 H4C11
Missing
[409]
HepG2.C3A H4C11
Missing
[410]
HuH.7 H4C11
Missing
[411]
SNU475 H4C11
Missing
[412]
THLE H4C11
Missing
[413]
liver H4C11
Missing
[414]
ref_hepatocyte H4C13
Missing
[415]
HepG2 H4C13
Missing
[416]
HepG2.C3A H4C13
Missing
[417]
HuH.7 H4C13
Missing
[418]
SNU475 H4C13
Missing
[419]
THLE H4C13
Missing
[420]
liver H4C13
Missing
[421]
ref_hepatocyte H2BC9
Missing
[422]
HepG2 H2BC9
Missing
[423]
HepG2.C3A H2BC9
Missing
[424]
HuH.7 H2BC9
Missing
[425]
SNU475 H2BC9
Missing
[426]
THLE H2BC9
Missing
[427]
liver H2BC9
Missing
[428]
ref_hepatocyte H2BC7
Missing
[429]
HepG2 H2BC7
Missing
[430]
HepG2.C3A H2BC7
Missing
[431]
HuH.7 H2BC7
Missing
[432]
SNU475 H2BC7
Missing
[433]
THLE H2BC7
Missing
[434]
liver H2BC7
Missing
[435]
ref_hepatocyte H4-16
Missing
[436]
HepG2 H4-16
Missing
[437]
HepG2.C3A H4-16
Missing
[438]
HuH.7 H4-16
Missing
[439]
SNU475 H4-16
Missing
[440]
THLE H4-16
Missing
[441]
liver H4-16
Missing
[442]
ref_hepatocyte H2BC3
Missing
[443]
HepG2 H2BC3
Missing
[444]
HepG2.C3A H2BC3
Missing
[445]
HuH.7 H2BC3
Missing
[446]
SNU475 H2BC3
Missing
[447]
THLE H2BC3
Missing
[448]
liver H2BC3
Missing
[449]
ref_hepatocyte BABAM2
Missing
[450]
HepG2 BABAM2
Missing
[451]
HepG2.C3A BABAM2
Missing
[452]
HuH.7 BABAM2
Missing
[453]
SNU475 BABAM2
Missing
[454]
THLE BABAM2
Missing
[455]
liver BABAM2
Missing
[456]
ref_hepatocyte H4C3
Missing
[457]
HepG2 H4C3
Missing
[458]
HepG2.C3A H4C3
Missing
[459]
HuH.7 H4C3
Missing
[460]
SNU475 H4C3
Missing
[461]
THLE H4C3
Missing
[462]
liver H4C3
Missing
[463]
ref_hepatocyte H4C9
Missing
[464]
HepG2 H4C9
Missing
[465]
HepG2.C3A H4C9
Missing
[466]
HuH.7 H4C9
Missing
[467]
SNU475 H4C9
Missing
[468]
THLE H4C9
Missing
[469]
liver H4C9
Missing
[470]
ref_hepatocyte H2BS1
Missing
[471]
HepG2 H2BS1
Missing
[472]
HepG2.C3A H2BS1
Missing
[473]
HuH.7 H2BS1
Missing
[474]
SNU475 H2BS1
Missing
[475]
THLE H2BS1
Missing
[476]
liver H2BS1
Missing
[477]
ref_hepatocyte H4C12
Missing
[478]
HepG2 H4C12
Missing
[479]
HepG2.C3A H4C12
Missing
[480]
HuH.7 H4C12
Missing
[481]
SNU475 H4C12
Missing
[482]
THLE H4C12
Missing
[483]
liver H4C12
Missing