REACTOME_NONCANONICAL_ACTIVATION_OF_NOTCH3 Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 YBX1 Nuclease-sensitive element-binding protein 1 [1] -0.35[2] -0.33[3] -0.29[4] -0.54[5] -0.26[6] -0.95[7]
2 APH1A Gamma-secretase subunit APH-1A [8] 0.57[9] 1.01[10] 0.84[11] 0.52[12] 0.34[13] 0.83[14]
3 PSENEN Gamma-secretase subunit PEN-2 [15] -1.43[16] -1.25[17] -1.18[18] -1.10[19] -1.60[20] -0.22[21]
4 NCSTN Nicastrin [22] 1.99[23] 1.31[24] 1.07[25] 1.88[26] 1.67[27] 2.23[28]
5 PSEN1 Presenilin-1 [29] 1.70[30] 2.08[31] 1.25[32] 2.04[33] 1.84[34] 2.84[35]
6 PSEN2 Presenilin-2 [36] -0.05[37] -0.74[38] -4.95[39] 0.87[40] -0.58[41] 1.75[42]
7 APH1B Gamma-secretase subunit APH-1B [43] 0.40[44] 1.38[45] 4.11[46] 3.88[47] 2.84[48] 3.07[49]
8 NOTCH3 Neurogenic locus notch homolog protein 3 [50] 4.71[51] 0.51[52] 6.08[53] 7.04[54] 4.80[55] 5.92[56]
[1]
ref_hepatocyte YBX1
Mean 305
Standard deviation 1.8e+02
Values 3.5e+02 5.8e+02 2.6e+02 2e+02 1.3e+02
[2]
HepG2 YBX1
Mean 339
Standard deviation 4.5
Values 3.4e+02 3.4e+02
[3]
HepG2.C3A YBX1
Mean 272
Standard deviation 55
Values 2.3e+02 3.1e+02
[4]
HuH.7 YBX1
Mean 355
Standard deviation 1.1e+02
Values 4.4e+02 2.3e+02 4e+02
[5]
SNU475 YBX1
Mean 223
Standard deviation 22
Values 2.4e+02 2.1e+02
[6]
THLE YBX1
Mean 322
Standard deviation 79
Values 2.7e+02 3.8e+02
[7]
liver YBX1
Mean 62.7
Standard deviation 12
Values 74 64 68 45
[8]
ref_hepatocyte APH1A
Mean 33
Standard deviation 14
Values 23 24 22 47 49
[9]
HepG2 APH1A
Mean 69.5
Standard deviation 1.3
Values 69 70
[10]
HepG2.C3A APH1A
Mean 75
Standard deviation 1.3
Values 76 74
[11]
HuH.7 APH1A
Mean 83.8
Standard deviation 7.5
Values 79 80 92
[12]
SNU475 APH1A
Mean 50.3
Standard deviation 16
Values 61 39
[13]
THLE APH1A
Mean 52.6
Standard deviation 11
Values 45 60
[14]
liver APH1A
Mean 23.2
Standard deviation 0.44
Values 23 24 23 24
[15]
ref_hepatocyte PSENEN
Mean 26.8
Standard deviation 21
Values 8.7 7.6 23 58 37
[16]
HepG2 PSENEN
Mean 14.1
Standard deviation 1.6
Values 13 15
[17]
HepG2.C3A PSENEN
Mean 12.7
Standard deviation 0.49
Values 12 13
[18]
HuH.7 PSENEN
Mean 16.9
Standard deviation 4
Values 17 13 21
[19]
SNU475 PSENEN
Mean 13.3
Standard deviation 0.61
Values 13 14
[20]
THLE PSENEN
Mean 11.1
Standard deviation 0.49
Values 11 11
[21]
liver PSENEN
Mean 9.09
Standard deviation 9.1
Values 17 1.1 17 1.3
[22]
ref_hepatocyte NCSTN
Mean 16.1
Standard deviation 1.3
Values 18 15 16 16 15
[23]
HepG2 NCSTN
Mean 90.9
Standard deviation 5.4
Values 95 87
[24]
HepG2.C3A NCSTN
Mean 45.1
Standard deviation 8.2
Values 51 39
[25]
HuH.7 NCSTN
Mean 48.2
Standard deviation 2.5
Values 47 46 51
[26]
SNU475 NCSTN
Mean 63.1
Standard deviation 12
Values 72 55
[27]
THLE NCSTN
Mean 65
Standard deviation 14
Values 55 75
[28]
liver NCSTN
Mean 30.1
Standard deviation 12
Values 32 22 46 20
[29]
ref_hepatocyte PSEN1
Mean 6.64
Standard deviation 2.1
Values 8.7 7.5 8.3 4.7 4.1
[30]
HepG2 PSEN1
Mean 30.5
Standard deviation 2.4
Values 29 32
[31]
HepG2.C3A PSEN1
Mean 31.6
Standard deviation 3.9
Values 34 29
[32]
HuH.7 PSEN1
Mean 22.5
Standard deviation 3.1
Values 23 25 19
[33]
SNU475 PSEN1
Mean 29.1
Standard deviation 1.1
Values 30 28
[34]
THLE PSEN1
Mean 30
Standard deviation 4
Values 27 33
[35]
liver PSEN1
Mean 18.8
Standard deviation 3
Values 15 22 19 19
[36]
ref_hepatocyte PSEN2
Mean 4.44
Standard deviation 2.5
Values 2.3 4.3 8.7 3.4 3.5
[37]
HepG2 PSEN2
Mean 6.08
Standard deviation 0.97
Values 6.8 5.4
[38]
HepG2.C3A PSEN2
Mean 2.99
Standard deviation 0.53
Values 3.4 2.6
[39]
HuH.7 PSEN2
Mean 0.204
Standard deviation 0.067
Values 0.13 0.22 0.26
[40]
SNU475 PSEN2
Mean 8.62
Standard deviation 2.2
Values 10 7.1
[41]
THLE PSEN2
Mean 3.74
Standard deviation 0.46
Values 3.4 4.1
[42]
liver PSEN2
Mean 5.9
Standard deviation 0.87
Values 7.1 5.8 5.8 5
[43]
ref_hepatocyte APH1B
Mean 0.759
Standard deviation 0.26
Values 0.86 1.2 0.64 0.63 0.5
[44]
HepG2 APH1B
Mean 1.42
Standard deviation 0.39
Values 1.7 1.1
[45]
HepG2.C3A APH1B
Mean 2.22
Standard deviation 0.15
Values 2.3 2.1
[46]
HuH.7 APH1B
Mean 18.6
Standard deviation 5.3
Values 23 13 20
[47]
SNU475 APH1B
Mean 11.9
Standard deviation 2.9
Values 14 9.9
[48]
THLE APH1B
Mean 6.86
Standard deviation 0.17
Values 7 6.7
[49]
liver APH1B
Mean 2.52
Standard deviation 0.52
Values 3 2.6 2.7 1.8
[50]
ref_hepatocyte NOTCH3
Mean 0.138
Standard deviation 0.22
Values 0.028 0.028 0.54 0.043 0.057
[51]
HepG2 NOTCH3
Mean 5.12
Standard deviation 6.5
Values 9.7 0.55
[52]
HepG2.C3A NOTCH3
Mean 0.222
Standard deviation 0.057
Values 0.26 0.18
[53]
HuH.7 NOTCH3
Mean 13.3
Standard deviation 4.1
Values 18 9.9 12
[54]
SNU475 NOTCH3
Mean 19.3
Standard deviation 5.2
Values 23 16
[55]
THLE NOTCH3
Mean 4.85
Standard deviation 2.7
Values 6.7 3
[56]
liver NOTCH3
Mean 3.33
Standard deviation 2.3
Values 2 4.1 1.1 6.2