REACTOME_NICOTINAMIDE_SALVAGING Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 NNMT Nicotinamide N-methyltransferase [1] -9.30[2] -10.92[3] -3.94[4] -3.29[5] -2.15[6] -0.68[7]
2 NAMPT Nicotinamide phosphoribosyltransferase [8] 1.31[9] 1.62[10] 1.88[11] 1.59[12] 2.47[13] 0.62[14]
3 CYP8B1 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase [15] -4.20[16] -1.95[17] -6.18[18] -7.50[19] -10.82[20] 2.09[21]
4 PARP9 Poly [ADP-ribose] polymerase 9 [22] 1.59[23] 0.67[24] 1.49[25] 1.91[26] -0.25[27] 0.98[28]
5 PARP10 Poly [ADP-ribose] polymerase 10 [29] 3.69[30] 2.64[31] -3.00[32] 2.89[33] 0.13[34] -0.11[35]
6 PARP14 Poly [ADP-ribose] polymerase 14 [36] 3.91[37] 3.74[38] 3.31[39] 4.21[40] 1.81[41] 2.65[42]
7 PARP4 Poly [ADP-ribose] polymerase 4 [43] 5.36[44] 5.47[45] 3.70[46] 4.78[47] 2.93[48] 1.45[49]
8 NUDT12 Peroxisomal NADH pyrophosphatase NUDT12 [50] 1.42[51] 2.50[52] 3.98[53] 1.62[54] 0.85[55] 0.64[56]
9 PARP16 Mono [ADP-ribose] polymerase PARP16 [57] 3.80[58] 3.79[59] 3.95[60] 1.70[61] -0.28[62] -0.13[63]
10 PARP8 Poly [ADP-ribose] polymerase 8 [64] 0.26[65] -1.87[66] 4.99[67] -3.12[68] 2.45[69] 1.16[70]
11 RNLS Renalase [71] -6.63[72] -5.43[73] 1.03[74] -1.05[75] -8.17[76] 0.27[77]
12 PARP6 Poly [ADP-ribose] polymerase 6 [78] -1.85[79] 0.60[80] 5.18[81] 4.02[82] 3.06[83] 1.21[84]
13 PTGIS Prostacyclin synthase [85] 2.46[86] 3.29[87] 6.96[88] 3.60[89] 8.05[90] 4.48[91]
14 PTGS2 Prostaglandin G/H synthase 2 [92] [93] 1.11[94] 1.05[95] 5.34[96] 9.67[97] 2.48[98]
15 SLC22A13 Solute carrier family 22 member 13 [99] 2.14[100] 1.33[101] 3.63[102] 2.82[103] 0.31[104] 1.04[105]
16 SLC5A8 Sodium-coupled monocarboxylate transporter 1 [106] [107] [108] [109] [110] [111] [112]
17 NAPRT Nicotinate phosphoribosyltransferase [113] [114] [115] [116] [117] [118] [119]
18 NAXE NAD(P)H-hydrate epimerase [120] [121] [122] [123] [124] [125] [126]
19 NAXD ATP-dependent (S)-NAD(P)H-hydrate dehydratase [127] [128] [129] [130] [131] [132] [133]
[1]
ref_hepatocyte NNMT
Mean 598
Standard deviation 7.3e+02
Values 0 59 1.3e+02 1.5e+03 1.3e+03
[2]
HepG2 NNMT
Mean 0.129
Standard deviation 0.13
Values 0.22 0.034
[3]
HepG2.C3A NNMT
Mean 0.0458
Standard deviation 0.004
Values 0.049 0.043
[4]
HuH.7 NNMT
Mean 6.86
Standard deviation 2.3
Values 7.3 4.3 8.9
[5]
SNU475 NNMT
Mean 20.1
Standard deviation 7.5
Values 15 25
[6]
THLE NNMT
Mean 139
Standard deviation 16
Values 1.5e+02 1.3e+02
[7]
liver NNMT
Mean 680
Standard deviation 4.7e+02
Values 1.1e+03 2.7e+02 1.1e+03 2.7e+02
[8]
ref_hepatocyte NAMPT
Mean 74.5
Standard deviation 39
Values 16 1.2e+02 57 95 89
[9]
HepG2 NAMPT
Mean 25.1
Standard deviation 8.5
Values 19 31
[10]
HepG2.C3A NAMPT
Mean 33.9
Standard deviation 3.2
Values 32 36
[11]
HuH.7 NAMPT
Mean 48.4
Standard deviation 12
Values 44 62 38
[12]
SNU475 NAMPT
Mean 74.1
Standard deviation 15
Values 63 85
[13]
THLE NAMPT
Mean 427
Standard deviation 55
Values 4.7e+02 3.9e+02
[14]
liver NAMPT
Mean 209
Standard deviation 33
Values 1.8e+02 2.5e+02 2.2e+02 1.9e+02
[15]
ref_hepatocyte CYP8B1
Mean 34.6
Standard deviation 44
Values 1.2 0.33 6.4 79 86
[16]
HepG2 CYP8B1
Mean 0.257
Standard deviation 0.2
Values 0.11 0.4
[17]
HepG2.C3A CYP8B1
Mean 1.33
Standard deviation 0.5
Values 1.7 0.98
[18]
HuH.7 CYP8B1
Mean 0.084
Standard deviation 0.016
Values 0.09 0.096 0.066
[19]
SNU475 CYP8B1
Mean 0.0631
Standard deviation 0.004
Values 0.06 0.066
[20]
THLE CYP8B1
Mean 0.0198
Standard deviation 0.0054
Values 0.024 0.016
[21]
liver CYP8B1
Mean 269
Standard deviation 1.3e+02
Values 4.2e+02 1.3e+02 3e+02 2.2e+02
[22]
ref_hepatocyte PARP9
Mean 16.3
Standard deviation 9.6
Values 4.7 24 7 22 24
[23]
HepG2 PARP9
Mean 6.71
Standard deviation 2.2
Values 5.2 8.3
[24]
HepG2.C3A PARP9
Mean 3.84
Standard deviation 0.82
Values 3.3 4.4
[25]
HuH.7 PARP9
Mean 8.09
Standard deviation 2.4
Values 6.6 11 6.9
[26]
SNU475 PARP9
Mean 20.3
Standard deviation 7.8
Values 26 15
[27]
THLE PARP9
Mean 14.3
Standard deviation 0.5
Values 14 15
[28]
liver PARP9
Mean 58.9
Standard deviation 14
Values 79 52 58 47
[29]
ref_hepatocyte PARP10
Mean 8.2
Standard deviation 4.5
Values 2 5.9 9.5 9.6 14
[30]
HepG2 PARP10
Mean 14.4
Standard deviation 0.73
Values 14 15
[31]
HepG2.C3A PARP10
Mean 7.59
Standard deviation 2.7
Values 9.5 5.7
[32]
HuH.7 PARP10
Mean 0.181
Standard deviation 0.067
Values 0.16 0.26 0.13
[33]
SNU475 PARP10
Mean 20.1
Standard deviation 7.5
Values 25 15
[34]
THLE PARP10
Mean 9.34
Standard deviation 0.97
Values 10 8.7
[35]
liver PARP10
Mean 13.9
Standard deviation 3
Values 14 13 11 18
[36]
ref_hepatocyte PARP14
Mean 6.53
Standard deviation 2.4
Values 7.3 10 5.1 4.7 5
[37]
HepG2 PARP14
Mean 13.3
Standard deviation 4.6
Values 10 17
[38]
HepG2.C3A PARP14
Mean 13
Standard deviation 2.7
Values 11 15
[39]
HuH.7 PARP14
Mean 11.4
Standard deviation 3.3
Values 10 15 8.8
[40]
SNU475 PARP14
Mean 39.8
Standard deviation 13
Values 49 31
[41]
THLE PARP14
Mean 23.8
Standard deviation 4.2
Values 27 21
[42]
liver PARP14
Mean 75
Standard deviation 40
Values 41 1e+02 41 1.2e+02
[43]
ref_hepatocyte PARP4
Mean 6.45
Standard deviation 2.5
Values 10 7 5.2 4.4 5.1
[44]
HepG2 PARP4
Mean 36.1
Standard deviation 9.6
Values 29 43
[45]
HepG2.C3A PARP4
Mean 42.5
Standard deviation 3.2
Values 40 45
[46]
HuH.7 PARP4
Mean 14.8
Standard deviation 1.9
Values 15 17 13
[47]
SNU475 PARP4
Mean 58.5
Standard deviation 13
Values 67 50
[48]
THLE PARP4
Mean 51.2
Standard deviation 16
Values 40 63
[49]
liver PARP4
Mean 32.1
Standard deviation 7.6
Values 26 43 31 28
[50]
ref_hepatocyte NUDT12
Mean 4.91
Standard deviation 4.7
Values 0.54 6.8 1.7 3.3 12
[51]
HepG2 NUDT12
Mean 1.79
Standard deviation 0.41
Values 1.5 2.1
[52]
HepG2.C3A NUDT12
Mean 4.11
Standard deviation 0.49
Values 3.8 4.5
[53]
HuH.7 NUDT12
Mean 13.6
Standard deviation 0.93
Values 15 13 14
[54]
SNU475 NUDT12
Mean 4.99
Standard deviation 1.7
Values 6.2 3.8
[55]
THLE NUDT12
Mean 9.17
Standard deviation 0.94
Values 8.5 9.8
[56]
liver NUDT12
Mean 14
Standard deviation 2.9
Values 18 14 13 11
[57]
ref_hepatocyte PARP16
Mean 2.46
Standard deviation 1.6
Values 1.5 0.83 1.5 4.5 3.9
[58]
HepG2 PARP16
Mean 4.65
Standard deviation 0.89
Values 4 5.3
[59]
HepG2.C3A PARP16
Mean 5.03
Standard deviation 0.93
Values 5.7 4.4
[60]
HuH.7 PARP16
Mean 6.69
Standard deviation 0.44
Values 6.8 7.1 6.2
[61]
SNU475 PARP16
Mean 2.64
Standard deviation 0.59
Values 3.1 2.2
[62]
THLE PARP16
Mean 2.11
Standard deviation 0.4
Values 1.8 2.4
[63]
liver PARP16
Mean 4.09
Standard deviation 2.4
Values 5.5 2.1 6.7 2.1
[64]
ref_hepatocyte PARP8
Mean 1.65
Standard deviation 1.1
Values 0.13 2.6 2.8 1.5 1.1
[65]
HepG2 PARP8
Mean 0.268
Standard deviation 0.075
Values 0.32 0.21
[66]
HepG2.C3A PARP8
Mean 0.0667
Standard deviation 0.012
Values 0.058 0.075
[67]
HuH.7 PARP8
Mean 9.23
Standard deviation 0.71
Values 9.2 10 8.5
[68]
SNU475 PARP8
Mean 0.0625
Standard deviation 0.062
Values 0.019 0.11
[69]
THLE PARP8
Mean 9.36
Standard deviation 1
Values 10 8.6
[70]
liver PARP8
Mean 6.7
Standard deviation 1.6
Values 5.7 7.7 5 8.3
[71]
ref_hepatocyte RNLS
Mean 1.56
Standard deviation 1.4
Values 0 2 0.35 1.9 3.5
[72]
HepG2 RNLS
Mean 0.00214
Standard deviation 0.003
Values 0 0.0043
[73]
HepG2.C3A RNLS
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[74]
HuH.7 RNLS
Mean 0.561
Standard deviation 0.086
Values 0.66 0.54 0.49
[75]
SNU475 RNLS
Mean 0.248
Standard deviation 0.11
Values 0.33 0.17
[76]
THLE RNLS
Mean 0.00562
Standard deviation 0.00042
Values 0.0059 0.0053
[77]
liver RNLS
Mean 3.42
Standard deviation 1.3
Values 4.9 2.5 4.2 2.1
[78]
ref_hepatocyte PARP6
Mean 1.36
Standard deviation 1.3
Values 0 0.45 3.2 1.9 1.3
[79]
HepG2 PARP6
Mean 0.0515
Standard deviation 6.9e-05
Values 0.052 0.051
[80]
HepG2.C3A PARP6
Mean 0.307
Standard deviation 0.12
Values 0.39 0.23
[81]
HuH.7 PARP6
Mean 8.73
Standard deviation 2.2
Values 6.4 11 8.9
[82]
SNU475 PARP6
Mean 7.3
Standard deviation 0.19
Values 7.2 7.4
[83]
THLE PARP6
Mean 11.8
Standard deviation 3.5
Values 14 9.4
[84]
liver PARP6
Mean 5.74
Standard deviation 2.9
Values 8.5 4.1 7.9 2.5
[85]
ref_hepatocyte PTGIS
Mean 0.218
Standard deviation 0.14
Values 0.14 0.08 0.32 0.4 0.15
[86]
HepG2 PTGIS
Mean 0.163
Standard deviation 0.012
Values 0.17 0.15
[87]
HepG2.C3A PTGIS
Mean 0.316
Standard deviation 0.0069
Values 0.32 0.31
[88]
HuH.7 PTGIS
Mean 4.77
Standard deviation 0.64
Values 5.5 4.3 4.5
[89]
SNU475 PTGIS
Mean 0.868
Standard deviation 0.11
Values 0.79 0.94
[90]
THLE PTGIS
Mean 59.9
Standard deviation 32
Values 37 82
[91]
liver PTGIS
Mean 8.86
Standard deviation 2.8
Values 5.9 11 12 7.1
[92]
ref_hepatocyte PTGS2
Mean 0.032
Standard deviation 0.045
Values 0 0 0 0.095 0.065
[93]
HepG2 PTGS2
Mean 0
Standard deviation 0
Values 0 0
[94]
HepG2.C3A PTGS2
Mean 0.0102
Standard deviation 0.00071
Values 0.0097 0.011
[95]
HuH.7 PTGS2
Mean 0.0117
Standard deviation 0.013
Values 0 0.026 0.0094
[96]
SNU475 PTGS2
Mean 0.428
Standard deviation 0.51
Values 0.07 0.79
[97]
THLE PTGS2
Mean 27
Standard deviation 7.8
Values 33 22
[98]
liver PTGS2
Mean 0.325
Standard deviation 0.24
Values 0.24 0.67 0.13 0.26
[99]
ref_hepatocyte SLC22A13
Mean 0.0275
Standard deviation 0.061
Values 0 0.14 0 0 0
[100]
HepG2 SLC22A13
Mean 0.0165
Standard deviation 0.0071
Values 0.011 0.021
[101]
HepG2.C3A SLC22A13
Mean 0.0102
Standard deviation 0.00071
Values 0.0097 0.011
[102]
HuH.7 SLC22A13
Mean 0.0599
Standard deviation 0.005
Values 0.066 0.058 0.056
[103]
SNU475 SLC22A13
Mean 0.0637
Standard deviation 0.025
Values 0.046 0.081
[104]
THLE SLC22A13
Mean 0.0352
Standard deviation 0.042
Values 0.065 0.0053
[105]
liver SLC22A13
Mean 0.103
Standard deviation 0.086
Values 0.071 0.14 0 0.2
[106]
ref_hepatocyte SLC5A8
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[107]
HepG2 SLC5A8
Missing
[108]
HepG2.C3A SLC5A8
Missing
[109]
HuH.7 SLC5A8
Missing
[110]
SNU475 SLC5A8
Missing
[111]
THLE SLC5A8
Missing
[112]
liver SLC5A8
Missing
[113]
ref_hepatocyte NAPRT
Missing
[114]
HepG2 NAPRT
Missing
[115]
HepG2.C3A NAPRT
Missing
[116]
HuH.7 NAPRT
Missing
[117]
SNU475 NAPRT
Missing
[118]
THLE NAPRT
Missing
[119]
liver NAPRT
Missing
[120]
ref_hepatocyte NAXE
Missing
[121]
HepG2 NAXE
Missing
[122]
HepG2.C3A NAXE
Missing
[123]
HuH.7 NAXE
Missing
[124]
SNU475 NAXE
Missing
[125]
THLE NAXE
Missing
[126]
liver NAXE
Missing
[127]
ref_hepatocyte NAXD
Missing
[128]
HepG2 NAXD
Missing
[129]
HepG2.C3A NAXD
Missing
[130]
HuH.7 NAXD
Missing
[131]
SNU475 NAXD
Missing
[132]
THLE NAXD
Missing
[133]
liver NAXD
Missing