REACTOME_NEUROTRANSMITTER_RELEASE_CYCLE | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | HSPA8 | Heat shock cognate 71 kDa protein | [1] | -0.01[2] | -0.43[3] | -0.30[4] | 0.05[5] | 0.09[6] | -1.51[7] |
2 | SLC22A1 | Solute carrier family 22 member 1 | [8] | -10.55[9] | -9.40[10] | -11.14[11] | -10.21[12] | -10.73[13] | 0.73[14] |
3 | ABAT | 4-aminobutyrate aminotransferase, mitochondrial | [15] | -0.24[16] | -0.94[17] | -1.84[18] | -9.28[19] | -7.11[20] | 0.73[21] |
4 | SLC38A2 | Sodium-coupled neutral amino acid transporter 2 | [22] | 1.24[23] | 2.45[24] | 0.74[25] | 0.20[26] | 1.10[27] | 1.02[28] |
5 | MAOA | Amine oxidase [flavin-containing] A | [29] | -2.89[30] | -2.53[31] | 0.56[32] | -4.56[33] | 0.97[34] | 1.06[35] |
6 | ARL6IP5 | PRA1 family protein 3 | [36] | -0.37[37] | -1.14[38] | -1.31[39] | 0.05[40] | 0.52[41] | -0.68[42] |
7 | GLS2 | Glutaminase liver isoform, mitochondrial | [43] | -2.18[44] | -2.02[45] | -5.52[46] | -7.01[47] | -6.14[48] | 0.04[49] |
8 | ALDH5A1 | Succinate-semialdehyde dehydrogenase, mitochondrial | [50] | 0.07[51] | -0.20[52] | -1.22[53] | -1.68[54] | -3.49[55] | 0.11[56] |
9 | NAAA | N-acylethanolamine-hydrolyzing acid amidase | [57] | -1.68[58] | -1.98[59] | -0.98[60] | -1.70[61] | -1.89[62] | -0.01[63] |
10 | SLC1A1 | Excitatory amino acid transporter 3 | [64] | -8.27[65] | -8.75[66] | -1.14[67] | -2.65[68] | -3.25[69] | 1.66[70] |
11 | GLS | Glutaminase kidney isoform, mitochondrial | [71] | 1.59[72] | 2.01[73] | 1.75[74] | 3.06[75] | 1.80[76] | -0.99[77] |
12 | VAMP2 | Vesicle-associated membrane protein 2 | [78] | -1.04[79] | -1.10[80] | 0.08[81] | -0.38[82] | -0.23[83] | -0.63[84] |
13 | DNAJC5 | DnaJ homolog subfamily C member 5 | [85] | 3.08[86] | 2.26[87] | 2.42[88] | 2.30[89] | 2.16[90] | 0.79[91] |
14 | LIN7A | Protein lin-7 homolog A | [92] | -1.22[93] | -1.38[94] | 0.22[95] | -4.67[96] | -4.63[97] | -1.24[98] |
15 | SLC6A12 | Sodium- and chloride-dependent betaine transporter | [99] | -1.62[100] | -3.72[101] | -1.62[102] | -5.28[103] | -8.31[104] | 0.10[105] |
16 | LIN7C | Protein lin-7 homolog C | [106] | -0.07[107] | 0.66[108] | 2.82[109] | -0.08[110] | 0.36[111] | 2.12[112] |
17 | PPFIA1 | Liprin-alpha-1 | [113] | 1.91[114] | 1.24[115] | 2.92[116] | 4.27[117] | 2.34[118] | 1.39[119] |
18 | SLC6A11 | Sodium- and chloride-dependent GABA transporter 3 | [120] | 0.77[121] | 0.38[122] | 1.56[123] | -8.82[124] | -7.28[125] | -8.93[126] |
19 | SLC6A1 | Sodium- and chloride-dependent GABA transporter 1 | [127] | -11.19[128] | [129] | -10.63[130] | -11.32[131] | -10.91[132] | 2.41[133] |
20 | UNC13B | Protein unc-13 homolog B | [134] | 2.08[135] | 1.76[136] | 3.25[137] | 0.46[138] | 1.40[139] | 2.13[140] |
21 | CASK | Peripheral plasma membrane protein CASK | [141] | 2.11[142] | 1.59[143] | 3.96[144] | 3.00[145] | 2.65[146] | 0.82[147] |
22 | SLC6A13 | Sodium- and chloride-dependent GABA transporter 2 | [148] | -7.08[149] | -6.04[150] | -2.32[151] | -5.17[152] | -5.64[153] | -0.16[154] |
23 | SLC1A2 | Excitatory amino acid transporter 2 | [155] | 1.92[156] | 2.29[157] | -3.36[158] | -3.39[159] | -5.40[160] | 4.12[161] |
24 | APBA1 | Amyloid-beta A4 precursor protein-binding family A member 1 | [162] | -7.11[163] | -7.77[164] | 2.10[165] | -2.01[166] | -2.26[167] | 1.90[168] |
25 | LIN7B | Protein lin-7 homolog B | [169] | -0.29[170] | -0.12[171] | 0.10[172] | -0.67[173] | -0.72[174] | -2.12[175] |
26 | RAB3A | Ras-related protein Rab-3A | [176] | 0.23[177] | -1.25[178] | 1.70[179] | -0.72[180] | -0.18[181] | -1.66[182] |
27 | SLC18A2 | Synaptic vesicular amine transporter | [183] | -0.72[184] | 1.20[185] | 2.39[186] | -0.14[187] | 0.93[188] | 2.85[189] |
28 | SYN1 | Synapsin-1 | [190] | -1.93[191] | 0.00[192] | [193] | -3.48[194] | 0.81[195] | -1.22[196] |
29 | STX1A | Syntaxin-1A | [197] | 1.25[198] | 0.79[199] | 0.13[200] | 2.68[201] | 2.03[202] | -1.60[203] |
30 | STXBP1 | Syntaxin-binding protein 1 | [204] | 2.04[205] | 2.02[206] | 3.28[207] | 4.28[208] | 4.48[209] | 0.40[210] |
31 | CPLX1 | Complexin-1 | [211] | -0.61[212] | -2.09[213] | 3.56[214] | -2.81[215] | -2.50[216] | -0.24[217] |
32 | PPFIA3 | Liprin-alpha-3 | [218] | 3.03[219] | 3.03[220] | 3.83[221] | 0.98[222] | 0.91[223] | -0.36[224] |
33 | SLC1A3 | Excitatory amino acid transporter 1 | [225] | -3.18[226] | -1.97[227] | 5.34[228] | 4.47[229] | 4.57[230] | 2.28[231] |
34 | SNAP25 | Synaptosomal-associated protein 25 | [232] | -3.19[233] | -3.42[234] | 3.08[235] | 2.54[236] | 4.93[237] | 0.60[238] |
35 | GAD1 | Glutamate decarboxylase 1 | [239] | 1.12[240] | 1.01[241] | 5.20[242] | -1.18[243] | 0.34[244] | -4.23[245] |
36 | SLC1A7 | Excitatory amino acid transporter 5 | [246] | 1.98[247] | 2.05[248] | 6.29[249] | -0.01[250] | -1.18[251] | 1.66[252] |
37 | SLC1A6 | Excitatory amino acid transporter 4 | [253] | -2.85[254] | [255] | [256] | -3.64[257] | [258] | -1.18[259] |
38 | SYN3 | Synapsin-3 | [260] | 3.51[261] | 4.89[262] | 2.22[263] | [264] | -3.88[265] | -0.83[266] |
39 | SYT1 | Synaptotagmin-1 | [267] | -1.79[268] | -2.97[269] | 6.49[270] | 7.27[271] | 3.79[272] | 3.78[273] |
40 | SLC22A2 | Solute carrier family 22 member 2 | [274] | [275] | -2.84[276] | -2.14[277] | 0.02[278] | -0.33[279] | [280] |
41 | SLC17A7 | Vesicular glutamate transporter 1 | [281] | 3.35[282] | 3.25[283] | 3.70[284] | 4.18[285] | 2.85[286] | 0.57[287] |
42 | SYN2 | Synapsin-2 | [288] | -0.13[289] | -0.63[290] | -0.34[291] | 3.44[292] | 4.45[293] | 1.36[294] |
43 | GAD2 | Glutamate decarboxylase 2 | [295] | [296] | [297] | [298] | [299] | [300] | [301] |
44 | CHAT | Choline O-acetyltransferase | [302] | [303] | [304] | [305] | 2.04[306] | [307] | [308] |
45 | PPFIA2 | Liprin-alpha-2 | [309] | 4.50[310] | 7.00[311] | 7.15[312] | 0.81[313] | 1.58[314] | 6.46[315] |
46 | PPFIA4 | Liprin-alpha-4 | [316] | [317] | [318] | [319] | [320] | [321] | [322] |
47 | SLC18A3 | Vesicular acetylcholine transporter | [323] | [324] | [325] | [326] | [327] | [328] | [329] |
48 | SLC32A1 | Vesicular inhibitory amino acid transporter | [330] | [331] | [332] | [333] | [334] | [335] | [336] |
49 | TSPOAP1 | Peripheral-type benzodiazepine receptor-associated protein 1 | [337] | [338] | [339] | [340] | [341] | [342] | [343] |
50 | RIMS1 | Regulating synaptic membrane exocytosis protein 1 | [344] | [345] | [346] | [347] | [348] | [349] | [350] |
51 | SLC5A7 | High affinity choline transporter 1 | [351] | [352] | [353] | [354] | [355] | [356] | [357] |