REACTOME_NEGATIVE_REGULATION_OF_NOTCH4_SIGNALING Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 UBB Polyubiquitin-B [1] -1.09[2] -1.12[3] -0.98[4] -1.53[5] -1.02[6] -0.41[7]
2 RPS27A Ubiquitin-40S ribosomal protein S27a [8] [9] [10] [11] [12] [13] [14]
3 UBC Polyubiquitin-C [15] -0.64[16] -0.37[17] -0.61[18] -0.68[19] -0.64[20] 0.04[21]
4 PSME1 Proteasome activator complex subunit 1 [22] -0.41[23] -1.96[24] -1.59[25] -1.39[26] -1.86[27] -0.91[28]
5 YWHAZ 14-3-3 protein zeta/delta [29] 0.54[30] 0.55[31] 0.86[32] 2.15[33] 0.79[34] -0.18[35]
6 PSME2 Proteasome activator complex subunit 2 [36] -0.23[37] -1.58[38] -1.67[39] -1.18[40] -1.40[41] -0.53[42]
7 PSMA7 Proteasome subunit alpha type-7 [43] 0.73[44] 0.89[45] -0.43[46] 0.45[47] 0.08[48] 0.49[49]
8 PSMB1 Proteasome subunit beta type-1 [50] 0.27[51] 0.44[52] -0.62[53] -0.80[54] 0.04[55] 0.33[56]
9 PSMB3 Proteasome subunit beta type-3 [57] -0.21[58] -0.95[59] 0.10[60] -0.82[61] -0.87[62] 0.03[63]
10 PSMB4 Proteasome subunit beta type-4 [64] 0.03[65] 0.25[66] 0.40[67] 0.61[68] 0.67[69] -0.30[70]
11 PSMB7 Proteasome subunit beta type-7 [71] -0.91[72] -0.85[73] -0.70[74] -1.17[75] -0.65[76] -0.74[77]
12 PSMB5 Proteasome subunit beta type-5 [78] 1.49[79] 0.11[80] 0.06[81] -0.44[82] -0.09[83] -0.26[84]
13 PSMA6 Proteasome subunit alpha type-6 [85] 1.62[86] 0.39[87] 0.34[88] 0.09[89] 0.18[90] -0.18[91]
14 PSMA4 Proteasome subunit alpha type-4 [92] -0.31[93] 0.41[94] 0.22[95] 0.39[96] 0.29[97] -0.26[98]
15 SKP1 S-phase kinase-associated protein 1 [99] 0.13[100] 0.69[101] -0.19[102] 0.75[103] 1.02[104] 0.77[105]
16 PSMC3 26S proteasome regulatory subunit 6A [106] -0.35[107] -0.35[108] 0.28[109] -0.81[110] -0.54[111] 0.21[112]
17 PSMA3 Proteasome subunit alpha type-3 [113] -0.93[114] 0.13[115] -0.53[116] -0.06[117] -0.44[118] -0.01[119]
18 PSMB6 Proteasome subunit beta type-6 [120] -0.38[121] -0.18[122] -0.02[123] -0.61[124] -0.80[125] 0.15[126]
19 PSMA2 Proteasome subunit alpha type-2 [127] -0.47[128] 0.55[129] 0.90[130] -0.12[131] 0.34[132] 0.37[133]
20 PSMD4 26S proteasome non-ATPase regulatory subunit 4 [134] 0.05[135] 0.12[136] 0.34[137] 0.59[138] 0.13[139] 0.05[140]
21 PSMD7 26S proteasome non-ATPase regulatory subunit 7 [141] -0.03[142] 0.40[143] 0.27[144] -0.50[145] 0.05[146] -0.13[147]
22 PSMD8 26S proteasome non-ATPase regulatory subunit 8 [148] 0.13[149] 0.44[150] 0.59[151] -0.22[152] 0.62[153] -0.10[154]
23 PSMD2 26S proteasome non-ATPase regulatory subunit 2 [155] 1.66[156] 0.91[157] 0.99[158] 0.89[159] 2.26[160] 0.93[161]
24 PSMC1 26S proteasome regulatory subunit 4 [162] -0.01[163] 0.11[164] -0.52[165] 1.07[166] 0.67[167] 0.09[168]
25 PSMA1 Proteasome subunit alpha type-1 [169] 0.17[170] 0.62[171] 0.70[172] 0.65[173] 0.23[174] 0.58[175]
26 UBA52 Ubiquitin-60S ribosomal protein L40 [176] 1.79[177] 1.86[178] 2.90[179] 0.72[180] 1.59[181] 0.81[182]
27 PSMC5 26S proteasome regulatory subunit 8 [183] 0.49[184] 0.44[185] 0.54[186] 0.06[187] 0.55[188] 0.35[189]
28 RBX1 E3 ubiquitin-protein ligase RBX1 [190] -0.94[191] -0.35[192] -0.47[193] -1.45[194] -0.98[195] -0.63[196]
29 PSMD3 26S proteasome non-ATPase regulatory subunit 3 [197] 0.89[198] 0.44[199] 1.05[200] 0.59[201] 0.89[202] 0.06[203]
30 PSMB8 Proteasome subunit beta type-8 [204] -1.51[205] -2.04[206] -9.24[207] 0.56[208] -0.67[209] -0.62[210]
31 PSMD14 26S proteasome non-ATPase regulatory subunit 14 [211] 0.06[212] 0.73[213] 1.00[214] 0.45[215] 0.56[216] -0.08[217]
32 PSMC4 26S proteasome regulatory subunit 6B [218] 0.49[219] 0.58[220] 0.53[221] 0.08[222] 0.27[223] 0.40[224]
33 PSMD6 26S proteasome non-ATPase regulatory subunit 6 [225] -0.66[226] -0.12[227] -1.19[228] -0.55[229] 0.34[230] -0.19[231]
34 PSMD13 26S proteasome non-ATPase regulatory subunit 13 [232] 0.53[233] 0.71[234] 1.22[235] 0.51[236] 0.10[237] -0.01[238]
35 PSMD12 26S proteasome non-ATPase regulatory subunit 12 [239] -0.29[240] -0.15[241] -0.44[242] 0.13[243] 0.28[244] -0.08[245]
36 AKT1 RAC-alpha serine/threonine-protein kinase [246] 1.19[247] 1.12[248] 0.04[249] 1.20[250] 1.27[251] 1.22[252]
37 PSMC6 26S proteasome regulatory subunit 10B [253] 0.01[254] 1.65[255] 0.48[256] 0.49[257] 0.50[258] 0.57[259]
38 PSMD11 26S proteasome non-ATPase regulatory subunit 11 [260] 0.89[261] 0.57[262] 1.17[263] 0.90[264] 1.13[265] 1.40[266]
39 PSMC2 26S proteasome regulatory subunit 7 [267] 0.65[268] 1.11[269] 0.90[270] 1.29[271] 1.20[272] 1.45[273]
40 PSME3 Proteasome activator complex subunit 3 [274] 1.87[275] 1.65[276] 1.35[277] 1.32[278] 1.66[279] 1.01[280]
41 PSMD1 26S proteasome non-ATPase regulatory subunit 1 [281] 1.63[282] 2.01[283] 1.91[284] 2.12[285] 2.21[286] 2.20[287]
42 PSMB10 Proteasome subunit beta type-10 [288] -1.09[289] -0.43[290] -2.31[291] -0.09[292] -1.17[293] 0.05[294]
43 PSMA5 Proteasome subunit alpha type-5 [295] 1.96[296] 2.45[297] 2.03[298] 2.18[299] 1.82[300] 2.04[301]
44 PSMF1 Proteasome inhibitor PI31 subunit [302] 2.34[303] 2.45[304] 1.27[305] 1.18[306] 1.02[307] 1.98[308]
45 PSMB2 Proteasome subunit beta type-2 [309] 2.12[310] 1.92[311] 2.32[312] 2.48[313] 2.54[314] 2.53[315]
46 PSMB9 Proteasome subunit beta type-9 [316] -1.88[317] -4.44[318] -6.74[319] 1.73[320] -0.46[321] -0.37[322]
47 PSMD9 26S proteasome non-ATPase regulatory subunit 9 [323] 0.50[324] 1.05[325] 0.08[326] 0.35[327] 0.87[328] 0.86[329]
48 CUL1 Cullin-1 [330] 0.73[331] 1.57[332] 1.11[333] 1.83[334] 1.54[335] 2.21[336]
49 PSMD10 26S proteasome non-ATPase regulatory subunit 10 [337] 1.05[338] 1.44[339] 1.47[340] 2.03[341] 1.42[342] 0.84[343]
50 PSMD5 26S proteasome non-ATPase regulatory subunit 5 [344] 1.47[345] 1.09[346] 2.66[347] 2.41[348] 2.57[349] 2.29[350]
51 TACC3 Transforming acidic coiled-coil-containing protein 3 [351] 2.69[352] 2.76[353] 3.92[354] 3.67[355] 3.64[356] -0.28[357]
52 FBXW7 F-box/WD repeat-containing protein 7 [358] 0.38[359] 1.21[360] 1.19[361] 0.35[362] 1.42[363] 2.62[364]
53 NOTCH4 Neurogenic locus notch homolog protein 4 [365] 1.68[366] 2.41[367] -0.24[368] -0.76[369] 1.90[370] 7.68[371]
54 SEM1 Putative protein SEM1, isoform 2 [372] [373] [374] [375] [376] [377] [378]
[1]
ref_hepatocyte UBB
Mean 764
Standard deviation 4.8e+02
Values 3.8e+02 3.5e+02 5.3e+02 1.2e+03 1.3e+03
[2]
HepG2 UBB
Mean 368
Standard deviation 39
Values 4e+02 3.4e+02
[3]
HepG2.C3A UBB
Mean 285
Standard deviation 14
Values 2.8e+02 3e+02
[4]
HuH.7 UBB
Mean 304
Standard deviation 40
Values 2.9e+02 2.7e+02 3.5e+02
[5]
SNU475 UBB
Mean 204
Standard deviation 3.3
Values 2.1e+02 2e+02
[6]
THLE UBB
Mean 315
Standard deviation 34
Values 2.9e+02 3.4e+02
[7]
liver UBB
Mean 296
Standard deviation 1.3e+02
Values 4.3e+02 2.1e+02 3.9e+02 1.5e+02
[8]
ref_hepatocyte RPS27A
Mean 499
Standard deviation 2.2e+02
Values 6.6e+02 6.1e+02 1.7e+02 6.8e+02 3.8e+02
[9]
HepG2 RPS27A
Missing
[10]
HepG2.C3A RPS27A
Missing
[11]
HuH.7 RPS27A
Missing
[12]
SNU475 RPS27A
Missing
[13]
THLE RPS27A
Missing
[14]
liver RPS27A
Missing
[15]
ref_hepatocyte UBC
Mean 480
Standard deviation 2.8e+02
Values 1.8e+02 3.5e+02 9.1e+02 5.8e+02 3.8e+02
[16]
HepG2 UBC
Mean 314
Standard deviation 38
Values 3.4e+02 2.9e+02
[17]
HepG2.C3A UBC
Mean 302
Standard deviation 41
Values 3.3e+02 2.7e+02
[18]
HuH.7 UBC
Mean 246
Standard deviation 64
Values 2.4e+02 3.1e+02 1.9e+02
[19]
SNU475 UBC
Mean 232
Standard deviation 63
Values 2.8e+02 1.9e+02
[20]
THLE UBC
Mean 257
Standard deviation 41
Values 2.3e+02 2.9e+02
[21]
liver UBC
Mean 254
Standard deviation 78
Values 2.2e+02 3.1e+02 3.3e+02 1.6e+02
[22]
ref_hepatocyte PSME1
Mean 170
Standard deviation 1e+02
Values 3.3e+02 2.1e+02 62 1.3e+02 1.2e+02
[23]
HepG2 PSME1
Mean 130
Standard deviation 5.3
Values 1.3e+02 1.3e+02
[24]
HepG2.C3A PSME1
Mean 35.5
Standard deviation 2.7
Values 37 34
[25]
HuH.7 PSME1
Mean 44.4
Standard deviation 6.3
Values 42 40 52
[26]
SNU475 PSME1
Mean 49.9
Standard deviation 11
Values 58 42
[27]
THLE PSME1
Mean 39
Standard deviation 3.9
Values 36 42
[28]
liver PSME1
Mean 46.5
Standard deviation 42
Values 90 10 76 10
[29]
ref_hepatocyte YWHAZ
Mean 161
Standard deviation 1.6e+02
Values 1.3e+02 4.3e+02 1.6e+02 40 41
[30]
HepG2 YWHAZ
Mean 239
Standard deviation 21
Values 2.2e+02 2.5e+02
[31]
HepG2.C3A YWHAZ
Mean 191
Standard deviation 28
Values 1.7e+02 2.1e+02
[32]
HuH.7 YWHAZ
Mean 229
Standard deviation 23
Values 2.5e+02 2.1e+02 2.3e+02
[33]
SNU475 YWHAZ
Mean 552
Standard deviation 94
Values 6.2e+02 4.9e+02
[34]
THLE YWHAZ
Mean 232
Standard deviation 39
Values 2e+02 2.6e+02
[35]
liver YWHAZ
Mean 73.1
Standard deviation 31
Values 81 60 1.1e+02 39
[36]
ref_hepatocyte PSME2
Mean 121
Standard deviation 29
Values 1.5e+02 95 87 1.4e+02 1.3e+02
[37]
HepG2 PSME2
Mean 105
Standard deviation 28
Values 86 1.2e+02
[38]
HepG2.C3A PSME2
Mean 32.8
Standard deviation 7.9
Values 27 38
[39]
HuH.7 PSME2
Mean 29.7
Standard deviation 12
Values 29 18 42
[40]
SNU475 PSME2
Mean 41.2
Standard deviation 7.7
Values 47 36
[41]
THLE PSME2
Mean 38.2
Standard deviation 3.2
Values 36 40
[42]
liver PSME2
Mean 42.9
Standard deviation 41
Values 82 9.1 74 6.7
[43]
ref_hepatocyte PSMA7
Mean 113
Standard deviation 13
Values 1.1e+02 1.1e+02 1e+02 1.3e+02 1.1e+02
[44]
HepG2 PSMA7
Mean 190
Standard deviation 1.8
Values 1.9e+02 1.9e+02
[45]
HepG2.C3A PSMA7
Mean 169
Standard deviation 38
Values 1.4e+02 2e+02
[46]
HuH.7 PSMA7
Mean 65.7
Standard deviation 23
Values 64 44 90
[47]
SNU475 PSMA7
Mean 119
Standard deviation 5.9
Values 1.2e+02 1.1e+02
[48]
THLE PSMA7
Mean 99.1
Standard deviation 16
Values 88 1.1e+02
[49]
liver PSMA7
Mean 81.3
Standard deviation 59
Values 1.4e+02 35 1.2e+02 27
[50]
ref_hepatocyte PSMB1
Mean 111
Standard deviation 42
Values 67 72 1.1e+02 1.6e+02 1.4e+02
[51]
HepG2 PSMB1
Mean 137
Standard deviation 2.1
Values 1.4e+02 1.4e+02
[52]
HepG2.C3A PSMB1
Mean 123
Standard deviation 25
Values 1e+02 1.4e+02
[53]
HuH.7 PSMB1
Mean 56.6
Standard deviation 17
Values 60 38 72
[54]
SNU475 PSMB1
Mean 49.4
Standard deviation 6.1
Values 54 45
[55]
THLE PSMB1
Mean 95.3
Standard deviation 15
Values 85 1.1e+02
[56]
liver PSMB1
Mean 71.7
Standard deviation 53
Values 1.3e+02 30 1.1e+02 24
[57]
ref_hepatocyte PSMB3
Mean 100
Standard deviation 50
Values 72 47 83 1.7e+02 1.3e+02
[58]
HepG2 PSMB3
Mean 88.3
Standard deviation 10
Values 81 95
[59]
HepG2.C3A PSMB3
Mean 42.2
Standard deviation 13
Values 33 52
[60]
HuH.7 PSMB3
Mean 84.1
Standard deviation 39
Values 96 41 1.2e+02
[61]
SNU475 PSMB3
Mean 43.8
Standard deviation 0.67
Values 44 43
[62]
THLE PSMB3
Mean 45.8
Standard deviation 5.3
Values 42 50
[63]
liver PSMB3
Mean 52.5
Standard deviation 43
Values 89 19 90 12
[64]
ref_hepatocyte PSMB4
Mean 98.7
Standard deviation 58
Values 36 54 87 1.7e+02 1.5e+02
[65]
HepG2 PSMB4
Mean 103
Standard deviation 0.16
Values 1e+02 1e+02
[66]
HepG2.C3A PSMB4
Mean 95.7
Standard deviation 14
Values 86 1.1e+02
[67]
HuH.7 PSMB4
Mean 102
Standard deviation 32
Values 99 72 1.3e+02
[68]
SNU475 PSMB4
Mean 116
Standard deviation 4
Values 1.2e+02 1.1e+02
[69]
THLE PSMB4
Mean 131
Standard deviation 8.9
Values 1.3e+02 1.4e+02
[70]
liver PSMB4
Mean 41.3
Standard deviation 26
Values 73 24 51 17
[71]
ref_hepatocyte PSMB7
Mean 98
Standard deviation 53
Values 36 63 1.7e+02 1.3e+02 92
[72]
HepG2 PSMB7
Mean 53.3
Standard deviation 0.53
Values 53 54
[73]
HepG2.C3A PSMB7
Mean 44.3
Standard deviation 6.7
Values 40 49
[74]
HuH.7 PSMB7
Mean 47.3
Standard deviation 12
Values 54 34 54
[75]
SNU475 PSMB7
Mean 33.7
Standard deviation 1.3
Values 35 33
[76]
THLE PSMB7
Mean 52
Standard deviation 18
Values 39 64
[77]
liver PSMB7
Mean 30.2
Standard deviation 25
Values 48 9.7 55 8.3
[78]
ref_hepatocyte PSMB5
Mean 95.4
Standard deviation 62
Values 2e+02 91 52 85 47
[79]
HepG2 PSMB5
Mean 274
Standard deviation 15
Values 2.6e+02 2.8e+02
[80]
HepG2.C3A PSMB5
Mean 84
Standard deviation 5.9
Values 80 88
[81]
HuH.7 PSMB5
Mean 77.7
Standard deviation 17
Values 75 62 96
[82]
SNU475 PSMB5
Mean 54.2
Standard deviation 7
Values 59 49
[83]
THLE PSMB5
Mean 74.7
Standard deviation 9.4
Values 68 81
[84]
liver PSMB5
Mean 40.9
Standard deviation 31
Values 72 16 63 12
[85]
ref_hepatocyte PSMA6
Mean 87.7
Standard deviation 20
Values 1.2e+02 71 96 87 68
[86]
HepG2 PSMA6
Mean 275
Standard deviation 37
Values 2.5e+02 3e+02
[87]
HepG2.C3A PSMA6
Mean 93.6
Standard deviation 36
Values 68 1.2e+02
[88]
HuH.7 PSMA6
Mean 87.1
Standard deviation 29
Values 86 59 1.2e+02
[89]
SNU475 PSMA6
Mean 71.9
Standard deviation 5.2
Values 76 68
[90]
THLE PSMA6
Mean 82.6
Standard deviation 5.6
Values 79 87
[91]
liver PSMA6
Mean 39.8
Standard deviation 29
Values 68 17 61 13
[92]
ref_hepatocyte PSMA4
Mean 81.7
Standard deviation 21
Values 86 1.1e+02 59 92 62
[93]
HepG2 PSMA4
Mean 67.2
Standard deviation 13
Values 58 77
[94]
HepG2.C3A PSMA4
Mean 88.1
Standard deviation 39
Values 61 1.2e+02
[95]
HuH.7 PSMA4
Mean 74.5
Standard deviation 25
Values 75 49 99
[96]
SNU475 PSMA4
Mean 82.5
Standard deviation 10
Values 90 75
[97]
THLE PSMA4
Mean 83.2
Standard deviation 9.8
Values 76 90
[98]
liver PSMA4
Mean 35.1
Standard deviation 23
Values 58 19 51 13
[99]
ref_hepatocyte SKP1
Mean 80.8
Standard deviation 44
Values 1.5e+02 92 24 71 71
[100]
HepG2 SKP1
Mean 90.4
Standard deviation 11
Values 83 98
[101]
HepG2.C3A SKP1
Mean 106
Standard deviation 20
Values 91 1.2e+02
[102]
HuH.7 SKP1
Mean 55.5
Standard deviation 13
Values 57 42 67
[103]
SNU475 SKP1
Mean 105
Standard deviation 22
Values 1.2e+02 89
[104]
THLE SKP1
Mean 137
Standard deviation 18
Values 1.2e+02 1.5e+02
[105]
liver SKP1
Mean 71
Standard deviation 55
Values 1.1e+02 27 1.3e+02 20
[106]
ref_hepatocyte PSMC3
Mean 79.4
Standard deviation 45
Values 57 1.6e+02 69 60 53
[107]
HepG2 PSMC3
Mean 63.8
Standard deviation 1.8
Values 65 63
[108]
HepG2.C3A PSMC3
Mean 50.5
Standard deviation 8.3
Values 45 56
[109]
HuH.7 PSMC3
Mean 75.6
Standard deviation 29
Values 90 42 95
[110]
SNU475 PSMC3
Mean 35
Standard deviation 3.9
Values 32 38
[111]
THLE PSMC3
Mean 45.7
Standard deviation 12
Values 37 54
[112]
liver PSMC3
Mean 47.3
Standard deviation 27
Values 68 29 73 20
[113]
ref_hepatocyte PSMA3
Mean 79.2
Standard deviation 13
Values 58 85 77 91 84
[114]
HepG2 PSMA3
Mean 42.3
Standard deviation 10
Values 35 50
[115]
HepG2.C3A PSMA3
Mean 70.3
Standard deviation 30
Values 49 92
[116]
HuH.7 PSMA3
Mean 42.9
Standard deviation 11
Values 45 31 53
[117]
SNU475 PSMA3
Mean 58.4
Standard deviation 7
Values 63 53
[118]
THLE PSMA3
Mean 48.8
Standard deviation 2.9
Values 47 51
[119]
liver PSMA3
Mean 40.3
Standard deviation 29
Values 71 18 58 14
[120]
ref_hepatocyte PSMB6
Mean 78.3
Standard deviation 38
Values 30 47 1.1e+02 1.2e+02 89
[121]
HepG2 PSMB6
Mean 61.3
Standard deviation 0.66
Values 61 62
[122]
HepG2.C3A PSMB6
Mean 56.3
Standard deviation 5.6
Values 52 60
[123]
HuH.7 PSMB6
Mean 60.7
Standard deviation 30
Values 62 30 89
[124]
SNU475 PSMB6
Mean 39.5
Standard deviation 1.5
Values 38 41
[125]
THLE PSMB6
Mean 37.4
Standard deviation 3.3
Values 35 40
[126]
liver PSMB6
Mean 44.5
Standard deviation 42
Values 80 8.9 81 7.3
[127]
ref_hepatocyte PSMA2
Mean 77.3
Standard deviation 38
Values 93 1.1e+02 13 75 94
[128]
HepG2 PSMA2
Mean 57
Standard deviation 13
Values 48 66
[129]
HepG2.C3A PSMA2
Mean 92
Standard deviation 34
Values 68 1.2e+02
[130]
HuH.7 PSMA2
Mean 113
Standard deviation 39
Values 1.1e+02 75 1.5e+02
[131]
SNU475 PSMA2
Mean 55.1
Standard deviation 4.7
Values 58 52
[132]
THLE PSMA2
Mean 81.3
Standard deviation 6.2
Values 77 86
[133]
liver PSMA2
Mean 51.3
Standard deviation 39
Values 92 19 77 17
[134]
ref_hepatocyte PSMD4
Mean 73.6
Standard deviation 14
Values 57 96 68 76 71
[135]
HepG2 PSMD4
Mean 77.8
Standard deviation 2.3
Values 79 76
[136]
HepG2.C3A PSMD4
Mean 65.2
Standard deviation 2.3
Values 64 67
[137]
HuH.7 PSMD4
Mean 72.9
Standard deviation 17
Values 76 55 88
[138]
SNU475 PSMD4
Mean 85.4
Standard deviation 3.7
Values 88 83
[139]
THLE PSMD4
Mean 67.2
Standard deviation 12
Values 59 76
[140]
liver PSMD4
Mean 39.1
Standard deviation 21
Values 60 24 55 18
[141]
ref_hepatocyte PSMD7
Mean 71.5
Standard deviation 43
Values 1.3e+02 1e+02 52 46 26
[142]
HepG2 PSMD7
Mean 71.3
Standard deviation 3.2
Values 74 69
[143]
HepG2.C3A PSMD7
Mean 76.6
Standard deviation 9.9
Values 70 84
[144]
HuH.7 PSMD7
Mean 67.7
Standard deviation 16
Values 71 51 81
[145]
SNU475 PSMD7
Mean 39.1
Standard deviation 8.7
Values 45 33
[146]
THLE PSMD7
Mean 61.8
Standard deviation 0.47
Values 62 62
[147]
liver PSMD7
Mean 33.6
Standard deviation 21
Values 50 18 53 14
[148]
ref_hepatocyte PSMD8
Mean 70.5
Standard deviation 49
Values 31 51 1.5e+02 81 38
[149]
HepG2 PSMD8
Mean 78.9
Standard deviation 4.6
Values 82 76
[150]
HepG2.C3A PSMD8
Mean 77.4
Standard deviation 9.8
Values 70 84
[151]
HuH.7 PSMD8
Mean 82.9
Standard deviation 22
Values 92 58 98
[152]
SNU475 PSMD8
Mean 46.6
Standard deviation 2.1
Values 45 48
[153]
THLE PSMD8
Mean 90
Standard deviation 0.46
Values 90 90
[154]
liver PSMD8
Mean 33.7
Standard deviation 17
Values 44 20 53 18
[155]
ref_hepatocyte PSMD2
Mean 63.5
Standard deviation 53
Values 31 1.4e+02 95 32 17
[156]
HepG2 PSMD2
Mean 205
Standard deviation 4.2
Values 2e+02 2.1e+02
[157]
HepG2.C3A PSMD2
Mean 96.7
Standard deviation 27
Values 78 1.2e+02
[158]
HuH.7 PSMD2
Mean 99
Standard deviation 33
Values 1.2e+02 62 1.1e+02
[159]
SNU475 PSMD2
Mean 90.6
Standard deviation 14
Values 80 1e+02
[160]
THLE PSMD2
Mean 253
Standard deviation 48
Values 2.2e+02 2.9e+02
[161]
liver PSMD2
Mean 62.3
Standard deviation 15
Values 67 47 81 55
[162]
ref_hepatocyte PSMC1
Mean 58.7
Standard deviation 19
Values 33 81 72 52 55
[163]
HepG2 PSMC1
Mean 59.4
Standard deviation 10
Values 52 67
[164]
HepG2.C3A PSMC1
Mean 51.6
Standard deviation 19
Values 38 65
[165]
HuH.7 PSMC1
Mean 32
Standard deviation 8.7
Values 35 22 39
[166]
SNU475 PSMC1
Mean 95.1
Standard deviation 4.3
Values 92 98
[167]
THLE PSMC1
Mean 78
Standard deviation 10
Values 71 85
[168]
liver PSMC1
Mean 32.1
Standard deviation 18
Values 48 20 47 14
[169]
ref_hepatocyte PSMA1
Mean 57.5
Standard deviation 12
Values 54 71 42 68 53
[170]
HepG2 PSMA1
Mean 66.1
Standard deviation 7.3
Values 61 71
[171]
HepG2.C3A PSMA1
Mean 71.9
Standard deviation 20
Values 58 86
[172]
HuH.7 PSMA1
Mean 73.1
Standard deviation 15
Values 77 56 86
[173]
SNU475 PSMA1
Mean 69.4
Standard deviation 7.2
Values 74 64
[174]
THLE PSMA1
Mean 56.1
Standard deviation 9.5
Values 49 63
[175]
liver PSMA1
Mean 44.2
Standard deviation 30
Values 71 22 69 14
[176]
ref_hepatocyte UBA52
Mean 57.3
Standard deviation 43
Values 14 23 49 1.2e+02 81
[177]
HepG2 UBA52
Mean 203
Standard deviation 20
Values 2.2e+02 1.9e+02
[178]
HepG2.C3A UBA52
Mean 169
Standard deviation 3.3
Values 1.7e+02 1.7e+02
[179]
HuH.7 UBA52
Mean 334
Standard deviation 46
Values 3.4e+02 2.8e+02 3.7e+02
[180]
SNU475 UBA52
Mean 72.9
Standard deviation 11
Values 65 81
[181]
THLE UBA52
Mean 144
Standard deviation 15
Values 1.3e+02 1.5e+02
[182]
liver UBA52
Mean 51.7
Standard deviation 26
Values 79 32 68 28
[183]
ref_hepatocyte PSMC5
Mean 54.8
Standard deviation 9.1
Values 41 60 54 65 55
[184]
HepG2 PSMC5
Mean 78.5
Standard deviation 1.9
Values 80 77
[185]
HepG2.C3A PSMC5
Mean 60.6
Standard deviation 6.4
Values 56 65
[186]
HuH.7 PSMC5
Mean 62.2
Standard deviation 21
Values 70 38 78
[187]
SNU475 PSMC5
Mean 43.9
Standard deviation 8.5
Values 38 50
[188]
THLE PSMC5
Mean 66.7
Standard deviation 5.2
Values 63 70
[189]
liver PSMC5
Mean 35.8
Standard deviation 27
Values 56 14 62 11
[190]
ref_hepatocyte RBX1
Mean 54.3
Standard deviation 41
Values 88 1.1e+02 7.4 33 36
[191]
HepG2 RBX1
Mean 28.8
Standard deviation 5.7
Values 25 33
[192]
HepG2.C3A RBX1
Mean 34.6
Standard deviation 13
Values 26 44
[193]
HuH.7 RBX1
Mean 30.6
Standard deviation 15
Values 29 17 46
[194]
SNU475 RBX1
Mean 15.3
Standard deviation 1.3
Values 16 14
[195]
THLE RBX1
Mean 23
Standard deviation 3.5
Values 21 25
[196]
liver RBX1
Mean 18
Standard deviation 18
Values 36 2.5 32 1.8
[197]
ref_hepatocyte PSMD3
Mean 50.7
Standard deviation 20
Values 36 68 75 46 29
[198]
HepG2 PSMD3
Mean 95.7
Standard deviation 2
Values 97 94
[199]
HepG2.C3A PSMD3
Mean 55.9
Standard deviation 1.4
Values 55 57
[200]
HuH.7 PSMD3
Mean 82.2
Standard deviation 11
Values 92 71 84
[201]
SNU475 PSMD3
Mean 58.8
Standard deviation 0.24
Values 59 59
[202]
THLE PSMD3
Mean 78.2
Standard deviation 15
Values 68 89
[203]
liver PSMD3
Mean 27.2
Standard deviation 3.5
Values 27 22 29 30
[204]
ref_hepatocyte PSMB8
Mean 50
Standard deviation 23
Values 41 85 23 53 49
[205]
HepG2 PSMB8
Mean 17.9
Standard deviation 0.68
Values 18 17
[206]
HepG2.C3A PSMB8
Mean 9.87
Standard deviation 0.25
Values 9.7 10
[207]
HuH.7 PSMB8
Mean 0.0647
Standard deviation 0.041
Values 0.098 0.077 0.019
[208]
SNU475 PSMB8
Mean 56.9
Standard deviation 13
Values 66 48
[209]
THLE PSMB8
Mean 26.2
Standard deviation 0.55
Values 26 27
[210]
liver PSMB8
Mean 16.7
Standard deviation 11
Values 24 7.1 29 6.7
[211]
ref_hepatocyte PSMD14
Mean 48.2
Standard deviation 36
Values 68 1e+02 24 28 19
[212]
HepG2 PSMD14
Mean 51.4
Standard deviation 7.4
Values 46 57
[213]
HepG2.C3A PSMD14
Mean 65
Standard deviation 18
Values 52 78
[214]
HuH.7 PSMD14
Mean 75.6
Standard deviation 22
Values 81 52 94
[215]
SNU475 PSMD14
Mean 50.8
Standard deviation 6.2
Values 46 55
[216]
THLE PSMD14
Mean 59.3
Standard deviation 6.5
Values 55 64
[217]
liver PSMD14
Mean 23.4
Standard deviation 12
Values 33 16 33 11
[218]
ref_hepatocyte PSMC4
Mean 47.3
Standard deviation 18
Values 37 37 76 54 32
[219]
HepG2 PSMC4
Mean 67.8
Standard deviation 3.3
Values 70 66
[220]
HepG2.C3A PSMC4
Mean 57.5
Standard deviation 10
Values 50 65
[221]
HuH.7 PSMC4
Mean 53.6
Standard deviation 17
Values 61 34 65
[222]
SNU475 PSMC4
Mean 38.6
Standard deviation 6.3
Values 34 43
[223]
THLE PSMC4
Mean 47.6
Standard deviation 4.4
Values 45 51
[224]
liver PSMC4
Mean 32
Standard deviation 15
Values 32 24 53 19
[225]
ref_hepatocyte PSMD6
Mean 44.4
Standard deviation 13
Values 40 61 53 34 33
[226]
HepG2 PSMD6
Mean 28.6
Standard deviation 3.9
Values 26 31
[227]
HepG2.C3A PSMD6
Mean 33.2
Standard deviation 8.3
Values 27 39
[228]
HuH.7 PSMD6
Mean 15.2
Standard deviation 3.6
Values 16 11 18
[229]
SNU475 PSMD6
Mean 23.5
Standard deviation 0.55
Values 23 24
[230]
THLE PSMD6
Mean 46.9
Standard deviation 11
Values 39 55
[231]
liver PSMD6
Mean 20
Standard deviation 9.8
Values 29 12 28 11
[232]
ref_hepatocyte PSMD13
Mean 41.8
Standard deviation 13
Values 24 47 55 49 34
[233]
HepG2 PSMD13
Mean 61.7
Standard deviation 0.89
Values 62 61
[234]
HepG2.C3A PSMD13
Mean 55.4
Standard deviation 8.9
Values 49 62
[235]
HuH.7 PSMD13
Mean 76.2
Standard deviation 19
Values 78 56 94
[236]
SNU475 PSMD13
Mean 45.9
Standard deviation 0.32
Values 46 46
[237]
THLE PSMD13
Mean 37.3
Standard deviation 9.1
Values 31 44
[238]
liver PSMD13
Mean 21.4
Standard deviation 12
Values 29 13 33 9.8
[239]
ref_hepatocyte PSMD12
Mean 39.8
Standard deviation 23
Values 42 66 59 17 16
[240]
HepG2 PSMD12
Mean 33.3
Standard deviation 4.9
Values 30 37
[241]
HepG2.C3A PSMD12
Mean 29.2
Standard deviation 8.8
Values 23 35
[242]
HuH.7 PSMD12
Mean 23
Standard deviation 4.3
Values 26 18 25
[243]
SNU475 PSMD12
Mean 33.7
Standard deviation 4.7
Values 30 37
[244]
THLE PSMD12
Mean 40.2
Standard deviation 2.6
Values 38 42
[245]
liver PSMD12
Mean 19.3
Standard deviation 7.1
Values 23 14 27 12
[246]
ref_hepatocyte AKT1
Mean 37.6
Standard deviation 15
Values 55 50 19 31 32
[247]
HepG2 AKT1
Mean 87.8
Standard deviation 2.3
Values 89 86
[248]
HepG2.C3A AKT1
Mean 66.6
Standard deviation 2.4
Values 65 68
[249]
HuH.7 AKT1
Mean 30.2
Standard deviation 6.6
Values 33 23 35
[250]
SNU475 AKT1
Mean 66.6
Standard deviation 14
Values 76 57
[251]
THLE AKT1
Mean 75.8
Standard deviation 6.1
Values 72 80
[252]
liver AKT1
Mean 45.1
Standard deviation 25
Values 34 48 20 79
[253]
ref_hepatocyte PSMC6
Mean 34.5
Standard deviation 8
Values 26 36 47 30 35
[254]
HepG2 PSMC6
Mean 35.5
Standard deviation 13
Values 26 45
[255]
HepG2.C3A PSMC6
Mean 87.8
Standard deviation 29
Values 68 1.1e+02
[256]
HuH.7 PSMC6
Mean 37.8
Standard deviation 6.7
Values 40 30 43
[257]
SNU475 PSMC6
Mean 37.4
Standard deviation 2.8
Values 39 35
[258]
THLE PSMC6
Mean 40.7
Standard deviation 2.1
Values 39 42
[259]
liver PSMC6
Mean 26.3
Standard deviation 13
Values 39 17 36 13
[260]
ref_hepatocyte PSMD11
Mean 34
Standard deviation 17
Values 35 40 59 22 13
[261]
HepG2 PSMD11
Mean 64.4
Standard deviation 5
Values 61 68
[262]
HepG2.C3A PSMD11
Mean 40.9
Standard deviation 7.3
Values 36 46
[263]
HuH.7 PSMD11
Mean 60
Standard deviation 16
Values 66 42 72
[264]
SNU475 PSMD11
Mean 48.8
Standard deviation 2.8
Values 51 47
[265]
THLE PSMD11
Mean 62.1
Standard deviation 6.7
Values 57 67
[266]
liver PSMD11
Mean 45.9
Standard deviation 23
Values 61 26 70 26
[267]
ref_hepatocyte PSMC2
Mean 30.3
Standard deviation 7.9
Values 18 38 37 30 28
[268]
HepG2 PSMC2
Mean 48.4
Standard deviation 12
Values 40 57
[269]
HepG2.C3A PSMC2
Mean 53.1
Standard deviation 20
Values 39 67
[270]
HuH.7 PSMC2
Mean 44.3
Standard deviation 6.6
Values 42 39 52
[271]
SNU475 PSMC2
Mean 57.3
Standard deviation 3.6
Values 60 55
[272]
THLE PSMC2
Mean 57.9
Standard deviation 7.7
Values 52 63
[273]
liver PSMC2
Mean 42.5
Standard deviation 14
Values 53 37 55 25
[274]
ref_hepatocyte PSME3
Mean 27.5
Standard deviation 17
Values 33 53 28 15 9.1
[275]
HepG2 PSME3
Mean 103
Standard deviation 6.3
Values 99 1.1e+02
[276]
HepG2.C3A PSME3
Mean 70.4
Standard deviation 23
Values 54 87
[277]
HuH.7 PSME3
Mean 55
Standard deviation 20
Values 71 33 62
[278]
SNU475 PSME3
Mean 52.9
Standard deviation 3.6
Values 50 56
[279]
THLE PSME3
Mean 72.7
Standard deviation 12
Values 64 81
[280]
liver PSME3
Mean 28.6
Standard deviation 20
Values 38 12 52 12
[281]
ref_hepatocyte PSMD1
Mean 23.1
Standard deviation 8.9
Values 27 37 19 18 15
[282]
HepG2 PSMD1
Mean 73.3
Standard deviation 23
Values 57 89
[283]
HepG2.C3A PSMD1
Mean 76
Standard deviation 25
Values 58 94
[284]
HuH.7 PSMD1
Mean 68
Standard deviation 16
Values 82 50 71
[285]
SNU475 PSMD1
Mean 77.8
Standard deviation 2.8
Values 76 80
[286]
THLE PSMD1
Mean 89.2
Standard deviation 8.5
Values 83 95
[287]
liver PSMD1
Mean 54.7
Standard deviation 7
Values 53 57 63 46
[288]
ref_hepatocyte PSMB10
Mean 21.4
Standard deviation 8.3
Values 14 18 15 25 34
[289]
HepG2 PSMB10
Mean 10.3
Standard deviation 1.4
Values 9.3 11
[290]
HepG2.C3A PSMB10
Mean 12.9
Standard deviation 3.5
Values 10 15
[291]
HuH.7 PSMB10
Mean 3.39
Standard deviation 1.3
Values 3.9 1.9 4.4
[292]
SNU475 PSMB10
Mean 15.5
Standard deviation 5.3
Values 19 12
[293]
THLE PSMB10
Mean 7.91
Standard deviation 0.37
Values 8.2 7.6
[294]
liver PSMB10
Mean 11.4
Standard deviation 8.7
Values 22 3.8 15 4.8
[295]
ref_hepatocyte PSMA5
Mean 20.1
Standard deviation 5
Values 14 23 16 27 20
[296]
HepG2 PSMA5
Mean 80.1
Standard deviation 12
Values 72 89
[297]
HepG2.C3A PSMA5
Mean 89.3
Standard deviation 20
Values 75 1e+02
[298]
HuH.7 PSMA5
Mean 64.3
Standard deviation 16
Values 60 51 82
[299]
SNU475 PSMA5
Mean 70.1
Standard deviation 12
Values 78 62
[300]
THLE PSMA5
Mean 59.1
Standard deviation 7
Values 54 64
[301]
liver PSMA5
Mean 42.5
Standard deviation 27
Values 66 24 66 15
[302]
ref_hepatocyte PSMF1
Mean 19.6
Standard deviation 4.8
Values 21 12 24 22 18
[303]
HepG2 PSMF1
Mean 102
Standard deviation 2.6
Values 1e+02 1e+02
[304]
HepG2.C3A PSMF1
Mean 87
Standard deviation 11
Values 95 79
[305]
HuH.7 PSMF1
Mean 37
Standard deviation 6.5
Values 44 31 36
[306]
SNU475 PSMF1
Mean 34.4
Standard deviation 2.7
Values 36 33
[307]
THLE PSMF1
Mean 33.2
Standard deviation 3.5
Values 31 36
[308]
liver PSMF1
Mean 39.9
Standard deviation 23
Values 58 19 61 21
[309]
ref_hepatocyte PSMB2
Mean 16.5
Standard deviation 1.8
Values 14 16 18 18 17
[310]
HepG2 PSMB2
Mean 73.3
Standard deviation 1.9
Values 72 75
[311]
HepG2.C3A PSMB2
Mean 50.6
Standard deviation 14
Values 41 61
[312]
HuH.7 PSMB2
Mean 64.4
Standard deviation 19
Values 74 42 77
[313]
SNU475 PSMB2
Mean 71
Standard deviation 2.8
Values 73 69
[314]
THLE PSMB2
Mean 80.1
Standard deviation 11
Values 72 88
[315]
liver PSMB2
Mean 48.8
Standard deviation 35
Values 76 19 82 19
[316]
ref_hepatocyte PSMB9
Mean 14.9
Standard deviation 12
Values 2.5 8 33 13 18
[317]
HepG2 PSMB9
Mean 4.13
Standard deviation 0.69
Values 4.6 3.6
[318]
HepG2.C3A PSMB9
Mean 0.557
Standard deviation 0.031
Values 0.53 0.58
[319]
HuH.7 PSMB9
Mean 0.109
Standard deviation 0.061
Values 0.074 0.18 0.075
[320]
SNU475 PSMB9
Mean 38.2
Standard deviation 14
Values 48 29
[321]
THLE PSMB9
Mean 9.04
Standard deviation 1.1
Values 9.8 8.2
[322]
liver PSMB9
Mean 5.94
Standard deviation 5.1
Values 11 1.5 10 1.5
[323]
ref_hepatocyte PSMD9
Mean 14.6
Standard deviation 5.9
Values 8.9 21 20 14 8.7
[324]
HepG2 PSMD9
Mean 21
Standard deviation 0.29
Values 21 21
[325]
HepG2.C3A PSMD9
Mean 24.5
Standard deviation 1.7
Values 23 26
[326]
HuH.7 PSMD9
Mean 12.1
Standard deviation 2.3
Values 12 10 15
[327]
SNU475 PSMD9
Mean 14.4
Standard deviation 1.5
Values 15 13
[328]
THLE PSMD9
Mean 22.3
Standard deviation 1.6
Values 21 23
[329]
liver PSMD9
Mean 13.6
Standard deviation 10
Values 24 4.7 21 4.5
[330]
ref_hepatocyte CUL1
Mean 14.3
Standard deviation 4.3
Values 13 22 12 14 11
[331]
HepG2 CUL1
Mean 24.2
Standard deviation 10
Values 17 31
[332]
HepG2.C3A CUL1
Mean 34.5
Standard deviation 8.6
Values 28 41
[333]
HuH.7 CUL1
Mean 24.2
Standard deviation 1.9
Values 26 22 25
[334]
SNU475 CUL1
Mean 39.3
Standard deviation 2.3
Values 41 38
[335]
THLE CUL1
Mean 34.6
Standard deviation 5.4
Values 31 38
[336]
liver CUL1
Mean 34
Standard deviation 1.6
Values 32 35 34 36
[337]
ref_hepatocyte PSMD10
Mean 9.63
Standard deviation 2.7
Values 12 11 5.1 9.9 10
[338]
HepG2 PSMD10
Mean 20.4
Standard deviation 4.5
Values 17 24
[339]
HepG2.C3A PSMD10
Mean 21.2
Standard deviation 4.2
Values 18 24
[340]
HuH.7 PSMD10
Mean 21
Standard deviation 3.8
Values 19 19 25
[341]
SNU475 PSMD10
Mean 30.3
Standard deviation 7.7
Values 36 25
[342]
THLE PSMD10
Mean 21.6
Standard deviation 3.4
Values 19 24
[343]
liver PSMD10
Mean 8.87
Standard deviation 4.2
Values 12 6.7 13 3.9
[344]
ref_hepatocyte PSMD5
Mean 6.3
Standard deviation 1.6
Values 4.2 8.6 6.9 5.8 6
[345]
HepG2 PSMD5
Mean 17.9
Standard deviation 4
Values 15 21
[346]
HepG2.C3A PSMD5
Mean 10.9
Standard deviation 4.1
Values 8 14
[347]
HuH.7 PSMD5
Mean 31.2
Standard deviation 3.2
Values 33 28 33
[348]
SNU475 PSMD5
Mean 25.9
Standard deviation 1.7
Values 27 25
[349]
THLE PSMD5
Mean 31.2
Standard deviation 4.5
Values 28 34
[350]
liver PSMD5
Mean 15.8
Standard deviation 4.9
Values 20 13 20 10
[351]
ref_hepatocyte TACC3
Mean 5.23
Standard deviation 5.7
Values 7.6 14 1.4 1.8 1.2
[352]
HepG2 TACC3
Mean 34.4
Standard deviation 1.7
Values 33 36
[353]
HepG2.C3A TACC3
Mean 28.8
Standard deviation 13
Values 20 38
[354]
HuH.7 TACC3
Mean 62
Standard deviation 35
Values 77 22 88
[355]
SNU475 TACC3
Mean 51.3
Standard deviation 3.7
Values 49 54
[356]
THLE TACC3
Mean 54.2
Standard deviation 18
Values 42 67
[357]
liver TACC3
Mean 2.22
Standard deviation 1
Values 1.5 2.4 3.6 1.4
[358]
ref_hepatocyte FBXW7
Mean 3.48
Standard deviation 1.5
Values 4.4 5.4 3.8 2 1.9
[359]
HepG2 FBXW7
Mean 4.61
Standard deviation 0.31
Values 4.4 4.8
[360]
HepG2.C3A FBXW7
Mean 6.56
Standard deviation 0.24
Values 6.4 6.7
[361]
HuH.7 FBXW7
Mean 6.19
Standard deviation 0.32
Values 6.5 6.1 5.9
[362]
SNU475 FBXW7
Mean 3.42
Standard deviation 0.12
Values 3.5 3.3
[363]
THLE FBXW7
Mean 7.75
Standard deviation 2.2
Values 9.3 6.2
[364]
liver FBXW7
Mean 11
Standard deviation 3.8
Values 10 15 6.1 13
[365]
ref_hepatocyte NOTCH4
Mean 0.117
Standard deviation 0.16
Values 0 0 0.03 0.18 0.37
[366]
HepG2 NOTCH4
Mean 0.383
Standard deviation 0.29
Values 0.59 0.18
[367]
HepG2.C3A NOTCH4
Mean 0.505
Standard deviation 0.14
Values 0.6 0.41
[368]
HuH.7 NOTCH4
Mean 0.0776
Standard deviation 0.023
Values 0.074 0.1 0.056
[369]
SNU475 NOTCH4
Mean 0.0534
Standard deviation 0.0034
Values 0.051 0.056
[370]
THLE NOTCH4
Mean 0.365
Standard deviation 0.019
Values 0.38 0.35
[371]
liver NOTCH4
Mean 12.3
Standard deviation 1.6
Values 13 11 11 14
[372]
ref_hepatocyte SEM1
Missing
[373]
HepG2 SEM1
Missing
[374]
HepG2.C3A SEM1
Missing
[375]
HuH.7 SEM1
Missing
[376]
SNU475 SEM1
Missing
[377]
THLE SEM1
Missing
[378]
liver SEM1
Missing