REACTOME_NEGATIVE_REGULATION_OF_NMDA_RECEPTOR_MEDIATED_NEURONAL_TRANSMISSION Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 CALM1 Calmodulin-1 [1] -0.33[2] -0.60[3] -0.44[4] 0.01[5] 0.03[6] 0.31[7]
2 CAMK1 Calcium/calmodulin-dependent protein kinase type 1 [8] -1.65[9] -0.52[10] -0.90[11] -3.03[12] -1.67[13] -2.26[14]
3 CAMK2D Calcium/calmodulin-dependent protein kinase type II subunit delta [15] -0.27[16] -0.27[17] 0.94[18] -0.89[19] -0.96[20] 0.10[21]
4 DLG1 Disks large homolog 1 [22] 0.66[23] 0.70[24] 0.26[25] -0.26[26] 0.48[27] 0.01[28]
5 CAMK2G Calcium/calmodulin-dependent protein kinase type II subunit gamma 0.37[29] 1.28[30] 0.58[31] 0.11[32] 0.42[33] -0.35[34]
6 PPM1F Protein phosphatase 1F [35] 1.24[36] 1.03[37] 0.54[38] 0.69[39] 0.44[40] -0.03[41]
7 CAMK2B Calcium/calmodulin-dependent protein kinase type II subunit beta [42] -2.94[43] -4.57[44] -7.84[45] -4.43[46] -3.05[47] -0.16[48]
8 DLG3 Disks large homolog 3 [49] 3.16[50] 2.45[51] -5.79[52] 0.48[53] 2.54[54] -0.76[55]
9 DLG4 Disks large homolog 4 [56] 2.38[57] 2.36[58] 0.80[59] 0.39[60] 3.34[61] 0.39[62]
10 PPM1E Protein phosphatase 1E [63] -3.77[64] -3.23[65] 3.74[66] -2.35[67] 0.08[68] 0.96[69]
11 DLG2 Disks large homolog 2 [70] -2.03[71] -2.08[72] -1.34[73] -2.27[74] -2.44[75] 1.43[76]
12 GRIN2D Glutamate receptor ionotropic, NMDA 2D [77] 4.08[78] 3.67[79] 3.68[80] 1.21[81] 0.91[82] -1.36[83]
13 NEFL Neurofilament light polypeptide [84] -2.41[85] [86] -1.22[87] 8.10[88] 1.49[89] [90]
14 CAMK4 Calcium/calmodulin-dependent protein kinase type IV [91] [92] -2.48[93] -3.44[94] -0.12[95] 2.68[96] 2.94[97]
15 GRIN2B Glutamate receptor ionotropic, NMDA 2B [98] -2.86[99] [100] [101] -0.48[102] -2.55[103] 0.56[104]
16 ACTN2 Alpha-actinin-2 [105] -0.13[106] -0.24[107] -2.84[108] 0.66[109] 1.12[110] 1.61[111]
17 GRIN2C Glutamate receptor ionotropic, NMDA 2C [112] 3.19[113] 4.53[114] 2.82[115] 1.92[116] 3.29[117] 2.64[118]
18 GRIN2A Glutamate receptor ionotropic, NMDA 2A [119] [120] [121] -1.62[122] 7.49[123] 0.75[124] 6.73[125]
19 CAMK2A Calcium/calmodulin-dependent protein kinase type II subunit alpha [126] [127] [128] [129] [130] [131] [132]
20 GRIN1 Glutamate receptor ionotropic, NMDA 1 [133] [134] [135] [136] [137] [138] [139]
21 LRRC7 Leucine-rich repeat-containing protein 7 [140] [141] [142] [143] [144] [145] [146]
[1]
ref_hepatocyte CALM1
Mean 29.2
Standard deviation 11
Values 17 40 21 28 40
[2]
HepG2 CALM1
Mean 67.9
Standard deviation 4.3
Values 65 71
[3]
HepG2.C3A CALM1
Mean 62
Standard deviation 16
Values 51 73
[4]
HuH.7 CALM1
Mean 81.9
Standard deviation 15
Values 90 64 92
[5]
SNU475 CALM1
Mean 160
Standard deviation 24
Values 1.8e+02 1.4e+02
[6]
THLE CALM1
Mean 109
Standard deviation 13
Values 1e+02 1.2e+02
[7]
liver CALM1
Mean 127
Standard deviation 70
Values 2.1e+02 80 1.7e+02 57
[8]
ref_hepatocyte CAMK1
Mean 9.39
Standard deviation 4.3
Values 2.5 11 8.3 13 13
[9]
HepG2 CAMK1
Mean 8.75
Standard deviation 1
Values 8 9.5
[10]
HepG2.C3A CAMK1
Mean 21.1
Standard deviation 0.67
Values 22 21
[11]
HuH.7 CAMK1
Mean 19.2
Standard deviation 6.6
Values 21 12 25
[12]
SNU475 CAMK1
Mean 6.26
Standard deviation 0.66
Values 5.8 6.7
[13]
THLE CAMK1
Mean 10.8
Standard deviation 0.013
Values 11 11
[14]
liver CAMK1
Mean 6.87
Standard deviation 3.5
Values 11 4.8 8.5 3.3
[15]
ref_hepatocyte CAMK2D
Mean 6.27
Standard deviation 4.6
Values 12 11 1.6 2.7 4.7
[16]
HepG2 CAMK2D
Mean 15.2
Standard deviation 5.9
Values 11 19
[17]
HepG2.C3A CAMK2D
Mean 16.7
Standard deviation 1.9
Values 15 18
[18]
HuH.7 CAMK2D
Mean 46.1
Standard deviation 5.5
Values 51 47 40
[19]
SNU475 CAMK2D
Mean 18.4
Standard deviation 4.5
Values 22 15
[20]
THLE CAMK2D
Mean 11.8
Standard deviation 1.2
Values 13 11
[21]
liver CAMK2D
Mean 23.7
Standard deviation 6.1
Values 33 21 22 19
[22]
ref_hepatocyte DLG1
Mean 6.05
Standard deviation 3.6
Values 12 6.5 3.2 3.8 4.7
[23]
HepG2 DLG1
Mean 28
Standard deviation 17
Values 16 40
[24]
HepG2.C3A DLG1
Mean 31.6
Standard deviation 2.9
Values 30 34
[25]
HuH.7 DLG1
Mean 27.7
Standard deviation 2.4
Values 30 25 28
[26]
SNU475 DLG1
Mean 27.5
Standard deviation 5.4
Values 31 24
[27]
THLE DLG1
Mean 30.8
Standard deviation 0.63
Values 31 30
[28]
liver DLG1
Mean 21.3
Standard deviation 8.3
Values 17 30 12 26
[29]
ref_hepatocyte CAMK2G
Mean 2.9
Standard deviation 1.2
Values 2.8 2.3 4.9 1.9 2.6
[30]
HepG2 CAMK2G
Mean 11
Standard deviation 0.61
Values 11 11
[31]
HepG2.C3A CAMK2G
Mean 22.6
Standard deviation 3.2
Values 25 20
[32]
HuH.7 CAMK2G
Mean 16.6
Standard deviation 0.56
Values 16 17 17
[33]
SNU475 CAMK2G
Mean 17.1
Standard deviation 1.1
Values 18 16
[34]
THLE CAMK2G
Mean 14.2
Standard deviation 0.22
Values 14 14
[35]
liver CAMK2G
Mean 7.98
Standard deviation 1
Values 9.1 7 7.2 8.6
[36]
ref_hepatocyte PPM1F
Mean 2.54
Standard deviation 1.6
Values 3.1 4.1 3.7 1.2 0.55
[37]
HepG2 PPM1F
Mean 17.5
Standard deviation 1.8
Values 19 16
[38]
HepG2.C3A PPM1F
Mean 16.8
Standard deviation 3.2
Values 19 15
[39]
HuH.7 PPM1F
Mean 14.1
Standard deviation 1.9
Values 15 12 15
[40]
SNU475 PPM1F
Mean 22.3
Standard deviation 3.2
Values 25 20
[41]
THLE PPM1F
Mean 12.6
Standard deviation 3.2
Values 10 15
[42]
liver PPM1F
Mean 8.74
Standard deviation 4.3
Values 4.4 13 5.8 11
[43]
ref_hepatocyte CAMK2B
Mean 0.643
Standard deviation 0.6
Values 0 1.1 0 0.9 1.3
[44]
HepG2 CAMK2B
Mean 0.245
Standard deviation 0.067
Values 0.29 0.2
[45]
HepG2.C3A CAMK2B
Mean 0.0871
Standard deviation 0.013
Values 0.078 0.097
[46]
HuH.7 CAMK2B
Mean 0.0107
Standard deviation 0.0051
Values 0.016 0.0064 0.0094
[47]
SNU475 CAMK2B
Mean 0.162
Standard deviation 0.072
Values 0.21 0.11
[48]
THLE CAMK2B
Mean 0.283
Standard deviation 0.15
Values 0.39 0.18
[49]
liver CAMK2B
Mean 2.02
Standard deviation 0.9
Values 1.5 2.2 3.2 1.2
[50]
ref_hepatocyte DLG3
Mean 0.517
Standard deviation 0.81
Values 2 0.18 0.23 0.095 0.12
[51]
HepG2 DLG3
Mean 13.5
Standard deviation 0.46
Values 14 13
[52]
HepG2.C3A DLG3
Mean 9.12
Standard deviation 0.22
Values 9.3 9
[53]
HuH.7 DLG3
Mean 0.0357
Standard deviation 0.01
Values 0.025 0.045 0.037
[54]
SNU475 DLG3
Mean 3.93
Standard deviation 0.59
Values 3.5 4.3
[55]
THLE DLG3
Mean 11
Standard deviation 0.3
Values 11 11
[56]
liver DLG3
Mean 1.07
Standard deviation 0.61
Values 0.78 1.3 0.41 1.8
[57]
ref_hepatocyte DLG4
Mean 0.259
Standard deviation 0.21
Values 0.17 0 0.16 0.45 0.51
[58]
HepG2 DLG4
Mean 3.93
Standard deviation 2.2
Values 5.5 2.3
[59]
HepG2.C3A DLG4
Mean 4.27
Standard deviation 0.27
Values 4.5 4.1
[60]
HuH.7 DLG4
Mean 1.73
Standard deviation 0.71
Values 1.3 2.5 1.3
[61]
SNU475 DLG4
Mean 1.85
Standard deviation 0.71
Values 1.3 2.4
[62]
THLE DLG4
Mean 9.6
Standard deviation 0.94
Values 10 8.9
[63]
liver DLG4
Mean 1.19
Standard deviation 1.3
Values 0.26 1.2 0.28 3
[64]
ref_hepatocyte PPM1E
Mean 0.204
Standard deviation 0.17
Values 0 0.11 0.17 0.41 0.33
[65]
HepG2 PPM1E
Mean 0.0437
Standard deviation 0.005
Values 0.04 0.047
[66]
HepG2.C3A PPM1E
Mean 0.0701
Standard deviation 0.038
Values 0.097 0.043
[67]
HuH.7 PPM1E
Mean 10.4
Standard deviation 2.3
Values 11 12 7.8
[68]
SNU475 PPM1E
Mean 0.218
Standard deviation 0.16
Values 0.11 0.33
[69]
THLE PPM1E
Mean 0.785
Standard deviation 0.33
Values 1 0.55
[70]
liver PPM1E
Mean 1.39
Standard deviation 0.68
Values 1.9 2.1 0.72 0.9
[71]
ref_hepatocyte DLG2
Mean 0.0959
Standard deviation 0.094
Values 0 0.21 0 0.12 0.15
[72]
HepG2 DLG2
Mean 0.0687
Standard deviation 0.024
Values 0.052 0.086
[73]
HepG2.C3A DLG2
Mean 0.0731
Standard deviation 0.048
Values 0.039 0.11
[74]
HuH.7 DLG2
Mean 0.145
Standard deviation 0.069
Values 0.098 0.22 0.11
[75]
SNU475 DLG2
Mean 0.108
Standard deviation 0.055
Values 0.07 0.15
[76]
THLE DLG2
Mean 0.0648
Standard deviation 0.0088
Values 0.071 0.059
[77]
liver DLG2
Mean 0.904
Standard deviation 0.38
Values 0.85 0.84 0.51 1.4
[78]
ref_hepatocyte GRIN2D
Mean 0.0598
Standard deviation 0.13
Values 0.3 0 0 0 0
[79]
HepG2 GRIN2D
Mean 2.96
Standard deviation 2.4
Values 4.6 1.3
[80]
HepG2.C3A GRIN2D
Mean 2.45
Standard deviation 0.75
Values 3 1.9
[81]
HuH.7 GRIN2D
Mean 2.93
Standard deviation 0.45
Values 3.5 2.7 2.6
[82]
SNU475 GRIN2D
Mean 0.755
Standard deviation 0.44
Values 0.44 1.1
[83]
THLE GRIN2D
Mean 0.41
Standard deviation 0.031
Values 0.43 0.39
[84]
liver GRIN2D
Mean 0.0818
Standard deviation 0.083
Values 0.024 0.17 0 0.13
[85]
ref_hepatocyte NEFL
Mean 0.0366
Standard deviation 0.031
Values 0 0.031 0.084 0.043 0.024
[86]
HepG2 NEFL
Mean 0.02
Standard deviation 0.0041
Values 0.023 0.017
[87]
HepG2.C3A NEFL
Mean 0
Standard deviation 0
Values 0 0
[88]
HuH.7 NEFL
Mean 0.0598
Standard deviation 0.045
Values 0.074 0.096 0.0094
[89]
SNU475 NEFL
Mean 54.6
Standard deviation 25
Values 73 37
[90]
THLE NEFL
Mean 0.376
Standard deviation 0.12
Values 0.29 0.46
[91]
liver NEFL
Mean 0
Standard deviation 0
Values 0 0 0 0
[92]
ref_hepatocyte CAMK4
Mean 0.0277
Standard deviation 0.046
Values 0 0.11 0 0 0.033
[93]
HepG2 CAMK4
Mean 0
Standard deviation 0
Values 0 0
[94]
HepG2.C3A CAMK4
Mean 0.0161
Standard deviation 0.023
Values 0 0.032
[95]
HuH.7 CAMK4
Mean 0.00975
Standard deviation 0.0086
Values 0.016 0.013 0
[96]
SNU475 CAMK4
Mean 0.139
Standard deviation 0.098
Values 0.07 0.21
[97]
THLE CAMK4
Mean 0.651
Standard deviation 0.27
Values 0.46 0.84
[98]
liver CAMK4
Mean 0.748
Standard deviation 0.17
Values 0.75 0.8 0.92 0.52
[99]
ref_hepatocyte GRIN2B
Mean 0.0213
Standard deviation 0.039
Values 0 0 0 0.017 0.089
[100]
HepG2 GRIN2B
Mean 0.00858
Standard deviation 0.012
Values 0 0.017
[101]
HepG2.C3A GRIN2B
Mean 0
Standard deviation 0
Values 0 0
[102]
HuH.7 GRIN2B
Mean 0
Standard deviation 0
Values 0 0 0
[103]
SNU475 GRIN2B
Mean 0.0833
Standard deviation 0.046
Values 0.12 0.051
[104]
THLE GRIN2B
Mean 0.0133
Standard deviation 0.019
Values 0 0.027
[105]
liver GRIN2B
Mean 0.11
Standard deviation 0.05
Values 0.12 0.1 0.051 0.17
[106]
ref_hepatocyte ACTN2
Mean 0.0201
Standard deviation 0.045
Values 0 0 0.1 0 0
[107]
HepG2 ACTN2
Mean 0.0537
Standard deviation 0.021
Values 0.069 0.039
[108]
HepG2.C3A ACTN2
Mean 0.055
Standard deviation 0.032
Values 0.078 0.032
[109]
HuH.7 ACTN2
Mean 0.0107
Standard deviation 0.019
Values 0 0.032 0
[110]
SNU475 ACTN2
Mean 0.173
Standard deviation 0.035
Values 0.15 0.2
[111]
THLE ACTN2
Mean 0.16
Standard deviation 0.075
Values 0.21 0.11
[112]
liver ACTN2
Mean 0.215
Standard deviation 0.35
Values 0.73 0.014 0 0.12
[113]
ref_hepatocyte GRIN2C
Mean 0.00517
Standard deviation 0.012
Values 0 0 0 0.026 0
[114]
HepG2 GRIN2C
Mean 0.137
Standard deviation 0.097
Values 0.21 0.069
[115]
HepG2.C3A GRIN2C
Mean 0.385
Standard deviation 0.077
Values 0.33 0.44
[116]
HuH.7 GRIN2C
Mean 0.14
Standard deviation 0.025
Values 0.12 0.13 0.17
[117]
SNU475 GRIN2C
Mean 0.106
Standard deviation 0.007
Values 0.11 0.1
[118]
THLE GRIN2C
Mean 0.185
Standard deviation 0.15
Values 0.29 0.08
[119]
liver GRIN2C
Mean 0.113
Standard deviation 0.079
Values 0.071 0.16 0.026 0.2
[120]
ref_hepatocyte GRIN2A
Mean 0.00172
Standard deviation 0.0039
Values 0 0 0 0.0086 0
[121]
HepG2 GRIN2A
Mean 0
Standard deviation 0
Values 0 0
[122]
HepG2.C3A GRIN2A
Mean 0
Standard deviation 0
Values 0 0
[123]
HuH.7 GRIN2A
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[124]
SNU475 GRIN2A
Mean 1.69
Standard deviation 0.46
Values 1.4 2
[125]
THLE GRIN2A
Mean 0.0106
Standard deviation 0.015
Values 0 0.021
[126]
liver GRIN2A
Mean 0.641
Standard deviation 0.48
Values 0.28 0.74 0.26 1.3
[127]
ref_hepatocyte CAMK2A
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[128]
HepG2 CAMK2A
Mean 0.0787
Standard deviation 0.022
Values 0.063 0.094
[129]
HepG2.C3A CAMK2A
Mean 0.0468
Standard deviation 0.025
Values 0.029 0.064
[130]
HuH.7 CAMK2A
Mean 0.0232
Standard deviation 0.016
Values 0.041 0.019 0.0094
[131]
SNU475 CAMK2A
Mean 1.25
Standard deviation 0.78
Values 1.8 0.69
[132]
THLE CAMK2A
Mean 0.231
Standard deviation 0.034
Values 0.21 0.26
[133]
liver CAMK2A
Mean 0.0104
Standard deviation 0.014
Values 0 0.029 0 0.013
[134]
ref_hepatocyte GRIN1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[135]
HepG2 GRIN1
Mean 0.68
Standard deviation 0.6
Values 1.1 0.25
[136]
HepG2.C3A GRIN1
Mean 0.154
Standard deviation 0.11
Values 0.23 0.075
[137]
HuH.7 GRIN1
Mean 0.0602
Standard deviation 0.028
Values 0.082 0.071 0.028
[138]
SNU475 GRIN1
Mean 0.0414
Standard deviation 0.006
Values 0.037 0.046
[139]
THLE GRIN1
Mean 0.00858
Standard deviation 0.0046
Values 0.012 0.0053
[140]
liver GRIN1
Mean 0
Standard deviation 0
Values 0 0 0 0
[141]
ref_hepatocyte LRRC7
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[142]
HepG2 LRRC7
Mean 0
Standard deviation 0
Values 0 0
[143]
HepG2.C3A LRRC7
Mean 0
Standard deviation 0
Values 0 0
[144]
HuH.7 LRRC7
Mean 1.23
Standard deviation 0.58
Values 1 1.9 0.79
[145]
SNU475 LRRC7
Mean 0.0559
Standard deviation 0.0069
Values 0.051 0.061
[146]
THLE LRRC7
Mean 0.156
Standard deviation 0.012
Values 0.15 0.16
[147]
liver LRRC7
Mean 0.238
Standard deviation 0.2
Values 0.14 0.26 0.051 0.5