REACTOME_NEGATIVE_REGULATION_OF_FLT3 Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 UBB Polyubiquitin-B [1] -0.17[2] -0.31[3] -0.44[4] -0.43[5] -0.21[6] 0.00[7]
2 RPS27A Ubiquitin-40S ribosomal protein S27a [8] [9] [10] [11] [12] [13] [14]
3 UBC Polyubiquitin-C [15] 0.28[16] 0.45[17] -0.07[18] 0.43[19] 0.17[20] 0.46[21]
4 UBA52 Ubiquitin-60S ribosomal protein L40 [22] 2.71[23] 2.68[24] 3.44[25] 1.82[26] 2.40[27] 1.23[28]
5 CSK Tyrosine-protein kinase CSK [29] 2.41[30] 1.97[31] 2.06[32] 2.34[33] 1.70[34] 1.02[35]
6 SOCS6 Suppressor of cytokine signaling 6 [36] 2.39[37] 3.30[38] 2.06[39] 3.68[40] 3.06[41] 3.71[42]
7 PTPRJ Receptor-type tyrosine-protein phosphatase eta [43] 0.96[44] 2.64[45] 3.68[46] 3.81[47] 3.61[48] 3.84[49]
8 SOCS2 Suppressor of cytokine signaling 2 [50] 1.23[51] -1.25[52] -3.29[53] 3.01[54] -2.96[55] 3.53[56]
9 SH2B3 SH2B adapter protein 3 [57] 3.15[58] 2.80[59] 2.74[60] 3.91[61] 4.50[62] 3.28[63]
10 FLT3LG Fms-related tyrosine kinase 3 ligand [64] -0.22[65] -0.07[66] 0.11[67] 0.02[68] 0.86[69] -0.28[70]
11 ABL2 Abelson tyrosine-protein kinase 2 [71] 4.11[72] 4.19[73] 4.85[74] 6.24[75] 6.19[76] 4.80[77]
12 SLA Src-like-adapter [78] -6.14[79] [80] -1.43[81] -0.65[82] -0.42[83] 4.14[84]
13 CBL E3 ubiquitin-protein ligase CBL [85] 6.48[86] 5.49[87] 5.43[88] 7.49[89] 6.73[90] 5.64[91]
14 SLA2 Src-like-adapter 2 [92] 3.71[93] 5.86[94] -1.08[95] -1.89[96] -2.38[97] 1.80[98]
15 FLT3 Receptor-type tyrosine-protein kinase FLT3 [99] [100] [101] -1.69[102] -0.44[103] [104] 4.80[105]
[1]
ref_hepatocyte UBB
Mean 764
Standard deviation 4.8e+02
Values 3.8e+02 3.5e+02 5.3e+02 1.2e+03 1.3e+03
[2]
HepG2 UBB
Mean 368
Standard deviation 39
Values 4e+02 3.4e+02
[3]
HepG2.C3A UBB
Mean 285
Standard deviation 14
Values 2.8e+02 3e+02
[4]
HuH.7 UBB
Mean 304
Standard deviation 40
Values 2.9e+02 2.7e+02 3.5e+02
[5]
SNU475 UBB
Mean 204
Standard deviation 3.3
Values 2.1e+02 2e+02
[6]
THLE UBB
Mean 315
Standard deviation 34
Values 2.9e+02 3.4e+02
[7]
liver UBB
Mean 296
Standard deviation 1.3e+02
Values 4.3e+02 2.1e+02 3.9e+02 1.5e+02
[8]
ref_hepatocyte RPS27A
Mean 499
Standard deviation 2.2e+02
Values 6.6e+02 6.1e+02 1.7e+02 6.8e+02 3.8e+02
[9]
HepG2 RPS27A
Missing
[10]
HepG2.C3A RPS27A
Missing
[11]
HuH.7 RPS27A
Missing
[12]
SNU475 RPS27A
Missing
[13]
THLE RPS27A
Missing
[14]
liver RPS27A
Missing
[15]
ref_hepatocyte UBC
Mean 480
Standard deviation 2.8e+02
Values 1.8e+02 3.5e+02 9.1e+02 5.8e+02 3.8e+02
[16]
HepG2 UBC
Mean 314
Standard deviation 38
Values 3.4e+02 2.9e+02
[17]
HepG2.C3A UBC
Mean 302
Standard deviation 41
Values 3.3e+02 2.7e+02
[18]
HuH.7 UBC
Mean 246
Standard deviation 64
Values 2.4e+02 3.1e+02 1.9e+02
[19]
SNU475 UBC
Mean 232
Standard deviation 63
Values 2.8e+02 1.9e+02
[20]
THLE UBC
Mean 257
Standard deviation 41
Values 2.3e+02 2.9e+02
[21]
liver UBC
Mean 254
Standard deviation 78
Values 2.2e+02 3.1e+02 3.3e+02 1.6e+02
[22]
ref_hepatocyte UBA52
Mean 57.3
Standard deviation 43
Values 14 23 49 1.2e+02 81
[23]
HepG2 UBA52
Mean 203
Standard deviation 20
Values 2.2e+02 1.9e+02
[24]
HepG2.C3A UBA52
Mean 169
Standard deviation 3.3
Values 1.7e+02 1.7e+02
[25]
HuH.7 UBA52
Mean 334
Standard deviation 46
Values 3.4e+02 2.8e+02 3.7e+02
[26]
SNU475 UBA52
Mean 72.9
Standard deviation 11
Values 65 81
[27]
THLE UBA52
Mean 144
Standard deviation 15
Values 1.3e+02 1.5e+02
[28]
liver UBA52
Mean 51.7
Standard deviation 26
Values 79 32 68 28
[29]
ref_hepatocyte CSK
Mean 10.6
Standard deviation 1.8
Values 11 8.9 13 9 11
[30]
HepG2 CSK
Mean 30.4
Standard deviation 3.7
Values 33 28
[31]
HepG2.C3A CSK
Mean 19.1
Standard deviation 3
Values 21 17
[32]
HuH.7 CSK
Mean 23.7
Standard deviation 5.3
Values 27 18 26
[33]
SNU475 CSK
Mean 19.3
Standard deviation 0.29
Values 19 20
[34]
THLE CSK
Mean 16.3
Standard deviation 1.9
Values 15 18
[35]
liver CSK
Mean 8.27
Standard deviation 2.7
Values 7.6 6.5 6.7 12
[36]
ref_hepatocyte SOCS6
Mean 3.82
Standard deviation 2.2
Values 3.9 7.5 2.4 2.5 2.7
[37]
HepG2 SOCS6
Mean 10.8
Standard deviation 2.5
Values 9.1 13
[38]
HepG2.C3A SOCS6
Mean 17.4
Standard deviation 1.2
Values 18 17
[39]
HuH.7 SOCS6
Mean 8.58
Standard deviation 0.94
Values 8.8 9.4 7.6
[40]
SNU475 SOCS6
Mean 17.6
Standard deviation 0.84
Values 17 18
[41]
THLE SOCS6
Mean 15.1
Standard deviation 1.1
Values 14 16
[42]
liver SOCS6
Mean 19.3
Standard deviation 6.3
Values 15 24 13 26
[43]
ref_hepatocyte PTPRJ
Mean 3.68
Standard deviation 1.9
Values 1.8 6.2 5 2 3.4
[44]
HepG2 PTPRJ
Mean 3.86
Standard deviation 2.6
Values 5.7 2
[45]
HepG2.C3A PTPRJ
Mean 10.6
Standard deviation 4.9
Values 14 7.2
[46]
HuH.7 PTPRJ
Mean 25.4
Standard deviation 13
Values 20 40 16
[47]
SNU475 PTPRJ
Mean 18.6
Standard deviation 4.4
Values 16 22
[48]
THLE PTPRJ
Mean 21.4
Standard deviation 4.2
Values 18 24
[49]
liver PTPRJ
Mean 20.4
Standard deviation 13
Values 12 28 7.1 34
[50]
ref_hepatocyte SOCS2
Mean 3.66
Standard deviation 2
Values 3.6 6.7 2.3 4.2 1.5
[51]
HepG2 SOCS2
Mean 4.62
Standard deviation 2.2
Values 3.1 6.2
[52]
HepG2.C3A SOCS2
Mean 0.708
Standard deviation 0.27
Values 0.52 0.9
[53]
HuH.7 SOCS2
Mean 0.201
Standard deviation 0.17
Values 0.14 0.4 0.066
[54]
SNU475 SOCS2
Mean 10.6
Standard deviation 6.9
Values 15 5.7
[55]
THLE SOCS2
Mean 0.224
Standard deviation 0.00099
Values 0.22 0.22
[56]
liver SOCS2
Mean 16.3
Standard deviation 15
Values 36 4.4 5.7 19
[57]
ref_hepatocyte SH2B3
Mean 3.01
Standard deviation 1.8
Values 1.5 5.4 4.5 2.2 1.4
[58]
HepG2 SH2B3
Mean 14.4
Standard deviation 3.2
Values 17 12
[59]
HepG2.C3A SH2B3
Mean 9.65
Standard deviation 3.7
Values 12 7
[60]
HuH.7 SH2B3
Mean 10.8
Standard deviation 1.3
Values 12 9.4 11
[61]
SNU475 SH2B3
Mean 16.2
Standard deviation 14
Values 6.5 26
[62]
THLE SH2B3
Mean 32.3
Standard deviation 2
Values 34 31
[63]
liver SH2B3
Mean 11.3
Standard deviation 4.4
Values 11 13 5.4 16
[64]
ref_hepatocyte FLT3LG
Mean 1.73
Standard deviation 1.8
Values 0 0 4.1 1.9 2.7
[65]
HepG2 FLT3LG
Mean 0.799
Standard deviation 0.045
Values 0.83 0.77
[66]
HepG2.C3A FLT3LG
Mean 0.761
Standard deviation 0.27
Values 0.95 0.57
[67]
HuH.7 FLT3LG
Mean 1.01
Standard deviation 0.09
Values 1 1.1 0.92
[68]
SNU475 FLT3LG
Mean 0.629
Standard deviation 0.022
Values 0.64 0.61
[69]
THLE FLT3LG
Mean 1.5
Standard deviation 0.22
Values 1.7 1.3
[70]
liver FLT3LG
Mean 0.55
Standard deviation 0.58
Values 1.3 0.1 0.62 0.15
[71]
ref_hepatocyte ABL2
Mean 1.19
Standard deviation 0.77
Values 1.7 2.2 1 0.56 0.42
[72]
HepG2 ABL2
Mean 11
Standard deviation 0.31
Values 11 11
[73]
HepG2.C3A ABL2
Mean 9.99
Standard deviation 2.5
Values 12 8.2
[74]
HuH.7 ABL2
Mean 18.4
Standard deviation 5
Values 21 22 13
[75]
SNU475 ABL2
Mean 32.2
Standard deviation 3
Values 30 34
[76]
THLE ABL2
Mean 41.4
Standard deviation 9.2
Values 35 48
[77]
liver ABL2
Mean 12.8
Standard deviation 7.7
Values 7.5 22 5.5 16
[78]
ref_hepatocyte SLA
Mean 0.749
Standard deviation 0.78
Values 0 0 1.8 0.84 1.1
[79]
HepG2 SLA
Mean 0.00573
Standard deviation 0.0081
Values 0.011 0
[80]
HepG2.C3A SLA
Mean 0
Standard deviation 0
Values 0 0
[81]
HuH.7 SLA
Mean 0.15
Standard deviation 0.21
Values 0.0082 0.39 0.056
[82]
SNU475 SLA
Mean 0.171
Standard deviation 0.2
Values 0.028 0.31
[83]
THLE SLA
Mean 0.265
Standard deviation 0.091
Values 0.2 0.33
[84]
liver SLA
Mean 5.08
Standard deviation 1.8
Values 3.4 4.9 4.4 7.6
[85]
ref_hepatocyte CBL
Mean 0.522
Standard deviation 0.26
Values 0.83 0.62 0.65 0.18 0.33
[86]
HepG2 CBL
Mean 25.2
Standard deviation 0.64
Values 26 25
[87]
HepG2.C3A CBL
Mean 10.8
Standard deviation 0.61
Values 11 10
[88]
HuH.7 CBL
Mean 12.1
Standard deviation 3
Values 15 11 9.5
[89]
SNU475 CBL
Mean 33.7
Standard deviation 5.1
Values 30 37
[90]
THLE CBL
Mean 26.4
Standard deviation 3.4
Values 24 29
[91]
liver CBL
Mean 10
Standard deviation 4.2
Values 5.8 14 7.1 14
[92]
ref_hepatocyte SLA2
Mean 0.327
Standard deviation 0.53
Values 1.3 0.047 0.11 0 0.21
[93]
HepG2 SLA2
Mean 2.31
Standard deviation 0.36
Values 2.6 2.1
[94]
HepG2.C3A SLA2
Mean 8.76
Standard deviation 0.24
Values 8.9 8.6
[95]
HuH.7 SLA2
Mean 0.0834
Standard deviation 0.039
Values 0.066 0.13 0.056
[96]
SNU475 SLA2
Mean 0.0317
Standard deviation 0.0054
Values 0.028 0.035
[97]
THLE SLA2
Mean 0.0299
Standard deviation 0.025
Values 0.012 0.048
[98]
liver SLA2
Mean 0.44
Standard deviation 0.44
Values 0.28 0.2 0.18 1.1
[99]
ref_hepatocyte FLT3
Mean 0.0374
Standard deviation 0.084
Values 0 0 0 0 0.19
[100]
HepG2 FLT3
Mean 0
Standard deviation 0
Values 0 0
[101]
HepG2.C3A FLT3
Mean 0
Standard deviation 0
Values 0 0
[102]
HuH.7 FLT3
Mean 0.00625
Standard deviation 0.011
Values 0 0 0.019
[103]
SNU475 FLT3
Mean 0.00992
Standard deviation 0.0075
Values 0.0046 0.015
[104]
THLE FLT3
Mean 0
Standard deviation 0
Values 0 0
[105]
liver FLT3
Mean 0.402
Standard deviation 0.15
Values 0.21 0.44 0.39 0.57