REACTOME_NEF_MEDIATES_DOWN_MODULATION_OF_CELL_SURFACE_RECEPTORS_BY_RECRUITING_THEM_TO_CLATHRIN_ADAPTERS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 B2M Beta-2-microglobulin [1] -1.70[2] -1.50[3] -2.23[4] -0.64[5] -0.59[6] 0.03[7]
2 HLA-A HLA class I histocompatibility antigen, A-68 alpha chain [8] 0.41[9] 0.65[10] -5.41[11] 0.39[12] -0.45[13] -1.45[14]
3 ARF1 ADP-ribosylation factor 1 [15] 0.39[16] 0.59[17] 0.90[18] 0.04[19] -0.10[20] -0.06[21]
4 AP2M1 AP-2 complex subunit mu [22] 1.80[23] 1.59[24] 1.02[25] 1.62[26] 2.32[27] 0.47[28]
5 AP2S1 AP-2 complex subunit sigma [29] -0.04[30] -0.07[31] 0.56[32] -0.10[33] 0.52[34] -0.39[35]
6 AP1S1 AP-1 complex subunit sigma-1A [36] 0.57[37] 0.26[38] 0.58[39] -0.35[40] -0.39[41] -2.17[42]
7 AP1M1 AP-1 complex subunit mu-1 [43] 1.57[44] 1.20[45] 2.19[46] 0.11[47] 0.44[48] 0.55[49]
8 CD4 T-cell surface glycoprotein CD4 [50] -4.17[51] -2.00[52] -4.70[53] -6.81[54] -8.67[55] 0.55[56]
9 AP2A1 AP-2 complex subunit alpha-1 [57] 2.79[58] 2.44[59] 3.20[60] 2.04[61] 2.31[62] 1.59[63]
10 AP1B1 AP-1 complex subunit beta-1 [64] 2.70[65] 2.02[66] 3.86[67] 1.85[68] 1.84[69] 2.12[70]
11 ATP6V1H V-type proton ATPase subunit H [71] 1.26[72] 1.14[73] 0.23[74] 1.27[75] 1.35[76] 0.07[77]
12 AP2B1 AP-2 complex subunit beta [78] 3.82[79] 3.54[80] 5.19[81] 3.19[82] 3.24[83] 1.57[84]
13 AP2A2 AP-2 complex subunit alpha-2 [85] 2.85[86] 2.68[87] 2.73[88] 1.49[89] 1.32[90] 1.30[91]
14 AP1G1 AP-1 complex subunit gamma-1 [92] 2.99[93] 3.26[94] 3.60[95] 2.35[96] 2.38[97] 2.56[98]
15 AP1S2 AP-1 complex subunit sigma-2 [99] -0.47[100] 0.18[101] -1.08[102] 0.35[103] 0.56[104] -0.17[105]
16 PACS1 Phosphofurin acidic cluster sorting protein 1 [106] 4.51[107] 2.84[108] 3.65[109] 3.50[110] 3.71[111] 0.74[112]
17 AP1S3 AP-1 complex subunit sigma-3 [113] 2.89[114] 2.50[115] 0.33[116] 0.59[117] 0.95[118] -0.67[119]
18 AP1M2 AP-1 complex subunit mu-2 [120] 2.92[121] 3.61[122] 4.87[123] 0.55[124] 0.39[125] -1.98[126]
19 LCK Tyrosine-protein kinase Lck [127] 4.36[128] 4.43[129] -5.64[130] -4.44[131] -4.45[132] 1.87[133]
20 CD28 T-cell-specific surface glycoprotein CD28 [134] -2.42[135] -1.56[136] -1.60[137] -1.70[138] -1.57[139] 1.75[140]
21 CD8B T-cell surface glycoprotein CD8 beta chain [141] 2.58[142] 0.93[143] 9.45[144] [145] -1.18[146] 3.75[147]
[1]
ref_hepatocyte B2M
Mean 1.02e+03
Standard deviation 6.9e+02
Values 3.7e+02 4.4e+02 7.8e+02 1.7e+03 1.8e+03
[2]
HepG2 B2M
Mean 232
Standard deviation 27
Values 2.1e+02 2.5e+02
[3]
HepG2.C3A B2M
Mean 239
Standard deviation 55
Values 2e+02 2.8e+02
[4]
HuH.7 B2M
Mean 145
Standard deviation 20
Values 1.3e+02 1.7e+02 1.4e+02
[5]
SNU475 B2M
Mean 773
Standard deviation 1.4e+02
Values 8.7e+02 6.8e+02
[6]
THLE B2M
Mean 787
Standard deviation 30
Values 7.7e+02 8.1e+02
[7]
liver B2M
Mean 957
Standard deviation 6e+02
Values 1.5e+03 6.1e+02 1.4e+03 3e+02
[8]
ref_hepatocyte HLA-A
Mean 230
Standard deviation 75
Values 2e+02 1.6e+02 1.9e+02 3.5e+02 2.5e+02
[9]
HepG2 HLA-A
Mean 225
Standard deviation 68
Values 2.7e+02 1.8e+02
[10]
HepG2.C3A HLA-A
Mean 238
Standard deviation 65
Values 2.8e+02 1.9e+02
[11]
HuH.7 HLA-A
Mean 3.61
Standard deviation 1.9
Values 2.4 5.8 2.7
[12]
SNU475 HLA-A
Mean 354
Standard deviation 9.1
Values 3.5e+02 3.6e+02
[13]
THLE HLA-A
Mean 195
Standard deviation 20
Values 2.1e+02 1.8e+02
[14]
liver HLA-A
Mean 77.2
Standard deviation 46
Values 1.3e+02 45 1e+02 33
[15]
ref_hepatocyte ARF1
Mean 151
Standard deviation 27
Values 1.7e+02 1.8e+02 1.6e+02 1.4e+02 1.1e+02
[16]
HepG2 ARF1
Mean 146
Standard deviation 9
Values 1.5e+02 1.4e+02
[17]
HepG2.C3A ARF1
Mean 150
Standard deviation 24
Values 1.7e+02 1.3e+02
[18]
HuH.7 ARF1
Mean 189
Standard deviation 16
Values 1.8e+02 2.1e+02 1.8e+02
[19]
SNU475 ARF1
Mean 183
Standard deviation 24
Values 2e+02 1.7e+02
[20]
THLE ARF1
Mean 163
Standard deviation 16
Values 1.5e+02 1.7e+02
[21]
liver ARF1
Mean 133
Standard deviation 83
Values 1.9e+02 61 2.2e+02 63
[22]
ref_hepatocyte AP2M1
Mean 41.6
Standard deviation 13
Values 28 39 35 63 44
[23]
HepG2 AP2M1
Mean 107
Standard deviation 14
Values 97 1.2e+02
[24]
HepG2.C3A AP2M1
Mean 83
Standard deviation 17
Values 71 95
[25]
HuH.7 AP2M1
Mean 56.4
Standard deviation 14
Values 67 40 62
[26]
SNU475 AP2M1
Mean 150
Standard deviation 32
Values 1.7e+02 1.3e+02
[27]
THLE AP2M1
Mean 241
Standard deviation 26
Values 2.2e+02 2.6e+02
[28]
liver AP2M1
Mean 52.8
Standard deviation 26
Values 55 35 89 32
[29]
ref_hepatocyte AP2S1
Mean 38.3
Standard deviation 23
Values 13 36 20 57 66
[30]
HepG2 AP2S1
Mean 27.5
Standard deviation 0.19
Values 28 27
[31]
HepG2.C3A AP2S1
Mean 24.1
Standard deviation 3.4
Values 22 27
[32]
HuH.7 AP2S1
Mean 37.6
Standard deviation 15
Values 43 21 49
[33]
SNU475 AP2S1
Mean 42
Standard deviation 3.1
Values 44 40
[34]
THLE AP2S1
Mean 63.5
Standard deviation 6.7
Values 59 68
[35]
liver AP2S1
Mean 26.7
Standard deviation 27
Values 53 3.8 46 3.4
[36]
ref_hepatocyte AP1S1
Mean 25.8
Standard deviation 15
Values 10 46 35 20 18
[37]
HepG2 AP1S1
Mean 28.3
Standard deviation 2.5
Values 27 30
[38]
HepG2.C3A AP1S1
Mean 20.4
Standard deviation 2.6
Values 19 22
[39]
HuH.7 AP1S1
Mean 25.7
Standard deviation 11
Values 25 16 37
[40]
SNU475 AP1S1
Mean 23.8
Standard deviation 3.8
Values 26 21
[41]
THLE AP1S1
Mean 22.7
Standard deviation 1.8
Values 21 24
[42]
liver AP1S1
Mean 5.27
Standard deviation 2.5
Values 7.1 4.2 7.5 2.2
[43]
ref_hepatocyte AP1M1
Mean 19.4
Standard deviation 4.9
Values 17 17 27 20 14
[44]
HepG2 AP1M1
Mean 42.3
Standard deviation 3.7
Values 45 40
[45]
HepG2.C3A AP1M1
Mean 29.5
Standard deviation 4.9
Values 33 26
[46]
HuH.7 AP1M1
Mean 58.9
Standard deviation 13
Values 71 45 61
[47]
SNU475 AP1M1
Mean 24.6
Standard deviation 4.4
Values 28 21
[48]
THLE AP1M1
Mean 30.3
Standard deviation 6
Values 26 35
[49]
liver AP1M1
Mean 26
Standard deviation 11
Values 35 14 36 19
[50]
ref_hepatocyte CD4
Mean 14.9
Standard deviation 25
Values 0.42 0 1.1 15 59
[51]
HepG2 CD4
Mean 0.611
Standard deviation 0.26
Values 0.42 0.8
[52]
HepG2.C3A CD4
Mean 2.47
Standard deviation 0.32
Values 2.2 2.7
[53]
HuH.7 CD4
Mean 0.383
Standard deviation 0.15
Values 0.28 0.55 0.32
[54]
SNU475 CD4
Mean 0.157
Standard deviation 0.028
Values 0.18 0.14
[55]
THLE CD4
Mean 0.0423
Standard deviation 0.0071
Values 0.047 0.037
[56]
liver CD4
Mean 20
Standard deviation 8
Values 22 15 30 13
[57]
ref_hepatocyte AP2A1
Mean 10.6
Standard deviation 3.7
Values 6.9 8.6 9.7 17 11
[58]
HepG2 AP2A1
Mean 54
Standard deviation 4.5
Values 57 51
[59]
HepG2.C3A AP2A1
Mean 38.1
Standard deviation 9.3
Values 45 32
[60]
HuH.7 AP2A1
Mean 65.1
Standard deviation 18
Values 85 50 60
[61]
SNU475 AP2A1
Mean 51.3
Standard deviation 9.3
Values 58 45
[62]
THLE AP2A1
Mean 60.6
Standard deviation 7.6
Values 55 66
[63]
liver AP2A1
Mean 29.1
Standard deviation 3.1
Values 28 27 27 34
[64]
ref_hepatocyte AP1B1
Mean 10.3
Standard deviation 4.1
Values 4.4 10 16 12 9.2
[65]
HepG2 AP1B1
Mean 49.3
Standard deviation 2.2
Values 48 51
[66]
HepG2.C3A AP1B1
Mean 27.6
Standard deviation 1.3
Values 27 29
[67]
HuH.7 AP1B1
Mean 99.8
Standard deviation 31
Values 1.3e+02 68 1e+02
[68]
SNU475 AP1B1
Mean 43.6
Standard deviation 7.4
Values 49 38
[69]
THLE AP1B1
Mean 42.7
Standard deviation 14
Values 33 52
[70]
liver AP1B1
Mean 41
Standard deviation 6.6
Values 32 41 47 44
[71]
ref_hepatocyte ATP6V1H
Mean 9.45
Standard deviation 4.2
Values 11 16 9 6 5.4
[72]
HepG2 ATP6V1H
Mean 16.7
Standard deviation 1.6
Values 16 18
[73]
HepG2.C3A ATP6V1H
Mean 13.8
Standard deviation 1.4
Values 15 13
[74]
HuH.7 ATP6V1H
Mean 7.42
Standard deviation 1.1
Values 6.7 8.7 6.9
[75]
SNU475 ATP6V1H
Mean 26.7
Standard deviation 6.6
Values 31 22
[76]
THLE ATP6V1H
Mean 27.9
Standard deviation 4.7
Values 25 31
[77]
liver ATP6V1H
Mean 9.12
Standard deviation 3.6
Values 13 6.6 11 5.6
[78]
ref_hepatocyte AP2B1
Mean 9
Standard deviation 4.1
Values 11 15 5.6 5.9 7.2
[79]
HepG2 AP2B1
Mean 93.9
Standard deviation 10
Values 87 1e+02
[80]
HepG2.C3A AP2B1
Mean 69.3
Standard deviation 14
Values 79 59
[81]
HuH.7 AP2B1
Mean 220
Standard deviation 43
Values 2.7e+02 2e+02 1.9e+02
[82]
SNU475 AP2B1
Mean 96.9
Standard deviation 32
Values 1.2e+02 74
[83]
THLE AP2B1
Mean 98.4
Standard deviation 18
Values 86 1.1e+02
[84]
liver AP2B1
Mean 24.4
Standard deviation 6.6
Values 18 34 23 23
[85]
ref_hepatocyte AP2A2
Mean 8.24
Standard deviation 1.1
Values 7.8 6.8 8.3 9.9 8.3
[86]
HepG2 AP2A2
Mean 43.6
Standard deviation 9.6
Values 50 37
[87]
HepG2.C3A AP2A2
Mean 34.8
Standard deviation 12
Values 43 26
[88]
HuH.7 AP2A2
Mean 36.5
Standard deviation 2.7
Values 39 36 34
[89]
SNU475 AP2A2
Mean 27.1
Standard deviation 8.1
Values 33 21
[90]
THLE AP2A2
Mean 23.9
Standard deviation 4.3
Values 21 27
[91]
liver AP2A2
Mean 18.6
Standard deviation 3.8
Values 21 19 13 22
[92]
ref_hepatocyte AP1G1
Mean 8.02
Standard deviation 3.6
Values 14 9.7 6.5 5.1 5.2
[93]
HepG2 AP1G1
Mean 46.9
Standard deviation 17
Values 35 59
[94]
HepG2.C3A AP1G1
Mean 50.7
Standard deviation 3.2
Values 48 53
[95]
HuH.7 AP1G1
Mean 65.1
Standard deviation 13
Values 80 60 55
[96]
SNU475 AP1G1
Mean 48.1
Standard deviation 6.4
Values 53 44
[97]
THLE AP1G1
Mean 48.3
Standard deviation 3.9
Values 45 51
[98]
liver AP1G1
Mean 43.3
Standard deviation 13
Values 29 58 36 50
[99]
ref_hepatocyte AP1S2
Mean 6.32
Standard deviation 7.1
Values 14 14 0.64 1.2 1.7
[100]
HepG2 AP1S2
Mean 3.37
Standard deviation 0.57
Values 3 3.8
[101]
HepG2.C3A AP1S2
Mean 4.74
Standard deviation 0.93
Values 4.1 5.4
[102]
HuH.7 AP1S2
Mean 2
Standard deviation 0.14
Values 2 1.9 2.1
[103]
SNU475 AP1S2
Mean 9.51
Standard deviation 0.27
Values 9.3 9.7
[104]
THLE AP1S2
Mean 10.8
Standard deviation 0.74
Values 10 11
[105]
liver AP1S2
Mean 5.16
Standard deviation 2.1
Values 6.6 4.3 7.2 2.6
[106]
ref_hepatocyte PACS1
Mean 2.69
Standard deviation 1.2
Values 4.7 3 2.1 2 1.7
[107]
HepG2 PACS1
Mean 45.1
Standard deviation 5.4
Values 41 49
[108]
HepG2.C3A PACS1
Mean 12.8
Standard deviation 2.8
Values 15 11
[109]
HuH.7 PACS1
Mean 22.5
Standard deviation 3.7
Values 23 26 19
[110]
SNU475 PACS1
Mean 35.9
Standard deviation 2.9
Values 38 34
[111]
THLE PACS1
Mean 40.8
Standard deviation 5.8
Values 37 45
[112]
liver PACS1
Mean 4.13
Standard deviation 1.2
Values 2.8 5.7 3.9 4.1
[113]
ref_hepatocyte AP1S3
Mean 2.18
Standard deviation 2.2
Values 2.4 5.9 1.7 0.4 0.49
[114]
HepG2 AP1S3
Mean 11.9
Standard deviation 0.34
Values 12 12
[115]
HepG2.C3A AP1S3
Mean 8.12
Standard deviation 5.2
Values 4.5 12
[116]
HuH.7 AP1S3
Mean 1.83
Standard deviation 0.89
Values 2.6 0.85 2.1
[117]
SNU475 AP1S3
Mean 3.87
Standard deviation 1.1
Values 4.6 3.1
[118]
THLE AP1S3
Mean 4.87
Standard deviation 1.4
Values 3.9 5.9
[119]
liver AP1S3
Mean 1.25
Standard deviation 0.16
Values 1.2 1.4 1.1 1.3
[120]
ref_hepatocyte AP1M2
Mean 1.63
Standard deviation 2.5
Values 6 0.8 0.99 0.16 0.19
[121]
HepG2 AP1M2
Mean 9.11
Standard deviation 2.7
Values 7.2 11
[122]
HepG2.C3A AP1M2
Mean 13.1
Standard deviation 4.7
Values 9.8 16
[123]
HuH.7 AP1M2
Mean 31.7
Standard deviation 6.8
Values 26 30 39
[124]
SNU475 AP1M2
Mean 2.8
Standard deviation 0.57
Values 3.2 2.4
[125]
THLE AP1M2
Mean 2.46
Standard deviation 0.78
Values 1.9 3
[126]
liver AP1M2
Mean 0.379
Standard deviation 0.17
Values 0.61 0.24 0.41 0.25
[127]
ref_hepatocyte LCK
Mean 0.319
Standard deviation 0.43
Values 0.11 0 0.49 0 0.99
[128]
HepG2 LCK
Mean 4.84
Standard deviation 4.4
Values 8 1.7
[129]
HepG2.C3A LCK
Mean 4.55
Standard deviation 0.16
Values 4.4 4.7
[130]
HuH.7 LCK
Mean 0.00428
Standard deviation 0.0074
Values 0 0.013 0
[131]
SNU475 LCK
Mean 0.0173
Standard deviation 0.011
Values 0.0093 0.025
[132]
THLE LCK
Mean 0.0169
Standard deviation 0.0013
Values 0.018 0.016
[133]
liver LCK
Mean 1.07
Standard deviation 0.51
Values 1.2 0.49 1.7 0.91
[134]
ref_hepatocyte CD28
Mean 0.0933
Standard deviation 0.1
Values 0.14 0 0 0.086 0.24
[135]
HepG2 CD28
Mean 0.0129
Standard deviation 0.018
Values 0 0.026
[136]
HepG2.C3A CD28
Mean 0.0209
Standard deviation 0.016
Values 0.0097 0.032
[137]
HuH.7 CD28
Mean 0.0205
Standard deviation 0.023
Values 0.0082 0.0064 0.047
[138]
SNU475 CD28
Mean 0.0338
Standard deviation 0.0047
Values 0.037 0.03
[139]
THLE CD28
Mean 0.0364
Standard deviation 0.0012
Values 0.035 0.037
[140]
liver CD28
Mean 0.288
Standard deviation 0.19
Values 0.094 0.27 0.23 0.56
[141]
ref_hepatocyte CD8B
Mean 0.0163
Standard deviation 0.036
Values 0 0 0 0 0.081
[142]
HepG2 CD8B
Mean 0.0715
Standard deviation 0.044
Values 0.04 0.1
[143]
HepG2.C3A CD8B
Mean 0.0204
Standard deviation 0.0014
Values 0.019 0.021
[144]
HuH.7 CD8B
Mean 7.57
Standard deviation 1.4
Values 7 6.5 9.2
[145]
SNU475 CD8B
Mean 0
Standard deviation 0
Values 0 0
[146]
THLE CD8B
Mean 0.00828
Standard deviation 0.0033
Values 0.0059 0.011
[147]
liver CD8B
Mean 0.201
Standard deviation 0.15
Values 0.21 0.13 0.41 0.053