REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 B2M Beta-2-microglobulin [1] -1.20[2] -1.05[3] -1.28[4] -0.39[5] -0.21[6] 0.10[7]
2 HLA-A HLA class I histocompatibility antigen, A-68 alpha chain [8] 0.91[9] 1.09[10] -4.45[11] 0.63[12] -0.07[13] -1.38[14]
3 AP1S1 AP-1 complex subunit sigma-1A [15] 1.07[16] 0.71[17] 1.54[18] -0.11[19] -0.02[20] -2.10[21]
4 AP1M1 AP-1 complex subunit mu-1 [22] 2.06[23] 1.65[24] 3.14[25] 0.36[26] 0.81[27] 0.62[28]
5 AP1B1 AP-1 complex subunit beta-1 [29] 3.20[30] 2.47[31] 4.82[32] 2.09[33] 2.22[34] 2.19[35]
6 AP1G1 AP-1 complex subunit gamma-1 [36] 3.49[37] 3.70[38] 4.56[39] 2.59[40] 2.75[41] 2.63[42]
7 AP1S2 AP-1 complex subunit sigma-2 [43] 0.03[44] 0.63[45] -0.12[46] 0.60[47] 0.93[48] -0.10[49]
8 PACS1 Phosphofurin acidic cluster sorting protein 1 [50] 5.00[51] 3.29[52] 4.60[53] 3.75[54] 4.09[55] 0.81[56]
9 AP1S3 AP-1 complex subunit sigma-3 [57] 3.39[58] 2.94[59] 1.29[60] 0.84[61] 1.33[62] -0.61[63]
10 AP1M2 AP-1 complex subunit mu-2 [64] 3.42[65] 4.06[66] 5.83[67] 0.79[68] 0.76[69] -1.91[70]
[1]
ref_hepatocyte B2M
Mean 1.02e+03
Standard deviation 6.9e+02
Values 3.7e+02 4.4e+02 7.8e+02 1.7e+03 1.8e+03
[2]
HepG2 B2M
Mean 232
Standard deviation 27
Values 2.1e+02 2.5e+02
[3]
HepG2.C3A B2M
Mean 239
Standard deviation 55
Values 2e+02 2.8e+02
[4]
HuH.7 B2M
Mean 145
Standard deviation 20
Values 1.3e+02 1.7e+02 1.4e+02
[5]
SNU475 B2M
Mean 773
Standard deviation 1.4e+02
Values 8.7e+02 6.8e+02
[6]
THLE B2M
Mean 787
Standard deviation 30
Values 7.7e+02 8.1e+02
[7]
liver B2M
Mean 957
Standard deviation 6e+02
Values 1.5e+03 6.1e+02 1.4e+03 3e+02
[8]
ref_hepatocyte HLA-A
Mean 230
Standard deviation 75
Values 2e+02 1.6e+02 1.9e+02 3.5e+02 2.5e+02
[9]
HepG2 HLA-A
Mean 225
Standard deviation 68
Values 2.7e+02 1.8e+02
[10]
HepG2.C3A HLA-A
Mean 238
Standard deviation 65
Values 2.8e+02 1.9e+02
[11]
HuH.7 HLA-A
Mean 3.61
Standard deviation 1.9
Values 2.4 5.8 2.7
[12]
SNU475 HLA-A
Mean 354
Standard deviation 9.1
Values 3.5e+02 3.6e+02
[13]
THLE HLA-A
Mean 195
Standard deviation 20
Values 2.1e+02 1.8e+02
[14]
liver HLA-A
Mean 77.2
Standard deviation 46
Values 1.3e+02 45 1e+02 33
[15]
ref_hepatocyte AP1S1
Mean 25.8
Standard deviation 15
Values 10 46 35 20 18
[16]
HepG2 AP1S1
Mean 28.3
Standard deviation 2.5
Values 27 30
[17]
HepG2.C3A AP1S1
Mean 20.4
Standard deviation 2.6
Values 19 22
[18]
HuH.7 AP1S1
Mean 25.7
Standard deviation 11
Values 25 16 37
[19]
SNU475 AP1S1
Mean 23.8
Standard deviation 3.8
Values 26 21
[20]
THLE AP1S1
Mean 22.7
Standard deviation 1.8
Values 21 24
[21]
liver AP1S1
Mean 5.27
Standard deviation 2.5
Values 7.1 4.2 7.5 2.2
[22]
ref_hepatocyte AP1M1
Mean 19.4
Standard deviation 4.9
Values 17 17 27 20 14
[23]
HepG2 AP1M1
Mean 42.3
Standard deviation 3.7
Values 45 40
[24]
HepG2.C3A AP1M1
Mean 29.5
Standard deviation 4.9
Values 33 26
[25]
HuH.7 AP1M1
Mean 58.9
Standard deviation 13
Values 71 45 61
[26]
SNU475 AP1M1
Mean 24.6
Standard deviation 4.4
Values 28 21
[27]
THLE AP1M1
Mean 30.3
Standard deviation 6
Values 26 35
[28]
liver AP1M1
Mean 26
Standard deviation 11
Values 35 14 36 19
[29]
ref_hepatocyte AP1B1
Mean 10.3
Standard deviation 4.1
Values 4.4 10 16 12 9.2
[30]
HepG2 AP1B1
Mean 49.3
Standard deviation 2.2
Values 48 51
[31]
HepG2.C3A AP1B1
Mean 27.6
Standard deviation 1.3
Values 27 29
[32]
HuH.7 AP1B1
Mean 99.8
Standard deviation 31
Values 1.3e+02 68 1e+02
[33]
SNU475 AP1B1
Mean 43.6
Standard deviation 7.4
Values 49 38
[34]
THLE AP1B1
Mean 42.7
Standard deviation 14
Values 33 52
[35]
liver AP1B1
Mean 41
Standard deviation 6.6
Values 32 41 47 44
[36]
ref_hepatocyte AP1G1
Mean 8.02
Standard deviation 3.6
Values 14 9.7 6.5 5.1 5.2
[37]
HepG2 AP1G1
Mean 46.9
Standard deviation 17
Values 35 59
[38]
HepG2.C3A AP1G1
Mean 50.7
Standard deviation 3.2
Values 48 53
[39]
HuH.7 AP1G1
Mean 65.1
Standard deviation 13
Values 80 60 55
[40]
SNU475 AP1G1
Mean 48.1
Standard deviation 6.4
Values 53 44
[41]
THLE AP1G1
Mean 48.3
Standard deviation 3.9
Values 45 51
[42]
liver AP1G1
Mean 43.3
Standard deviation 13
Values 29 58 36 50
[43]
ref_hepatocyte AP1S2
Mean 6.32
Standard deviation 7.1
Values 14 14 0.64 1.2 1.7
[44]
HepG2 AP1S2
Mean 3.37
Standard deviation 0.57
Values 3 3.8
[45]
HepG2.C3A AP1S2
Mean 4.74
Standard deviation 0.93
Values 4.1 5.4
[46]
HuH.7 AP1S2
Mean 2
Standard deviation 0.14
Values 2 1.9 2.1
[47]
SNU475 AP1S2
Mean 9.51
Standard deviation 0.27
Values 9.3 9.7
[48]
THLE AP1S2
Mean 10.8
Standard deviation 0.74
Values 10 11
[49]
liver AP1S2
Mean 5.16
Standard deviation 2.1
Values 6.6 4.3 7.2 2.6
[50]
ref_hepatocyte PACS1
Mean 2.69
Standard deviation 1.2
Values 4.7 3 2.1 2 1.7
[51]
HepG2 PACS1
Mean 45.1
Standard deviation 5.4
Values 41 49
[52]
HepG2.C3A PACS1
Mean 12.8
Standard deviation 2.8
Values 15 11
[53]
HuH.7 PACS1
Mean 22.5
Standard deviation 3.7
Values 23 26 19
[54]
SNU475 PACS1
Mean 35.9
Standard deviation 2.9
Values 38 34
[55]
THLE PACS1
Mean 40.8
Standard deviation 5.8
Values 37 45
[56]
liver PACS1
Mean 4.13
Standard deviation 1.2
Values 2.8 5.7 3.9 4.1
[57]
ref_hepatocyte AP1S3
Mean 2.18
Standard deviation 2.2
Values 2.4 5.9 1.7 0.4 0.49
[58]
HepG2 AP1S3
Mean 11.9
Standard deviation 0.34
Values 12 12
[59]
HepG2.C3A AP1S3
Mean 8.12
Standard deviation 5.2
Values 4.5 12
[60]
HuH.7 AP1S3
Mean 1.83
Standard deviation 0.89
Values 2.6 0.85 2.1
[61]
SNU475 AP1S3
Mean 3.87
Standard deviation 1.1
Values 4.6 3.1
[62]
THLE AP1S3
Mean 4.87
Standard deviation 1.4
Values 3.9 5.9
[63]
liver AP1S3
Mean 1.25
Standard deviation 0.16
Values 1.2 1.4 1.1 1.3
[64]
ref_hepatocyte AP1M2
Mean 1.63
Standard deviation 2.5
Values 6 0.8 0.99 0.16 0.19
[65]
HepG2 AP1M2
Mean 9.11
Standard deviation 2.7
Values 7.2 11
[66]
HepG2.C3A AP1M2
Mean 13.1
Standard deviation 4.7
Values 9.8 16
[67]
HuH.7 AP1M2
Mean 31.7
Standard deviation 6.8
Values 26 30 39
[68]
SNU475 AP1M2
Mean 2.8
Standard deviation 0.57
Values 3.2 2.4
[69]
THLE AP1M2
Mean 2.46
Standard deviation 0.78
Values 1.9 3
[70]
liver AP1M2
Mean 0.379
Standard deviation 0.17
Values 0.61 0.24 0.41 0.25