REACTOME_NEF_AND_SIGNAL_TRANSDUCTION Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 RAC1 Ras-related C3 botulinum toxin substrate 1 [1] -0.53[2] -0.50[3] -0.36[4] -0.17[5] -0.48[6] -1.15[7]
2 PAK2 Serine/threonine-protein kinase PAK 2 [8] 1.31[9] 1.42[10] 1.14[11] 0.57[12] 0.82[13] 1.19[14]
3 FYN Tyrosine-protein kinase Fyn [15] 0.81[16] -7.43[17] 0.56[18] 1.28[19] 2.51[20] 0.79[21]
4 HCK Tyrosine-protein kinase HCK [22] -5.98[23] -5.80[24] [25] -5.45[26] -6.69[27] 0.53[28]
5 ELMO1 Engulfment and cell motility protein 1 [29] -5.94[30] -3.90[31] -0.27[32] -3.74[33] -6.85[34] 2.67[35]
6 CD247 T-cell surface glycoprotein CD3 zeta chain [36] -5.00[37] -5.31[38] -7.39[39] -3.70[40] -5.38[41] -0.19[42]
7 LCK Tyrosine-protein kinase Lck [43] 2.64[44] 3.08[45] -7.48[46] -5.27[47] -5.77[48] 1.05[49]
8 DOCK2 Dedicator of cytokinesis protein 2 [50] -4.58[51] [52] -6.96[53] 2.30[54] 0.89[55] 4.15[56]
[1]
ref_hepatocyte RAC1
Mean 52
Standard deviation 20
Values 28 59 81 45 47
[2]
HepG2 RAC1
Mean 87.4
Standard deviation 1.9
Values 89 86
[3]
HepG2.C3A RAC1
Mean 62
Standard deviation 7.4
Values 67 57
[4]
HuH.7 RAC1
Mean 97.2
Standard deviation 9.7
Values 1e+02 86 1e+02
[5]
SNU475 RAC1
Mean 96.5
Standard deviation 10
Values 89 1e+02
[6]
THLE RAC1
Mean 107
Standard deviation 19
Values 94 1.2e+02
[7]
liver RAC1
Mean 37.8
Standard deviation 32
Values 63 12 67 9.5
[8]
ref_hepatocyte PAK2
Mean 10.9
Standard deviation 2.8
Values 11 15 11 7.6 9.9
[9]
HepG2 PAK2
Mean 65.6
Standard deviation 14
Values 56 75
[10]
HepG2.C3A PAK2
Mean 49.1
Standard deviation 0.79
Values 49 50
[11]
HuH.7 PAK2
Mean 57.7
Standard deviation 11
Values 66 61 46
[12]
SNU475 PAK2
Mean 33.8
Standard deviation 4.3
Values 37 31
[13]
THLE PAK2
Mean 55.3
Standard deviation 9.9
Values 48 62
[14]
liver PAK2
Mean 39.9
Standard deviation 5.7
Values 44 41 43 32
[15]
ref_hepatocyte FYN
Mean 2.1
Standard deviation 2.2
Values 2.2 0.039 0.23 2.6 5.5
[16]
HepG2 FYN
Mean 8.91
Standard deviation 0.7
Values 9.4 8.4
[17]
HepG2.C3A FYN
Mean 0.0204
Standard deviation 0.0014
Values 0.019 0.021
[18]
HuH.7 FYN
Mean 7.43
Standard deviation 2.2
Values 8.9 4.8 8.5
[19]
SNU475 FYN
Mean 10.7
Standard deviation 2.5
Values 12 8.9
[20]
THLE FYN
Mean 34.5
Standard deviation 4.9
Values 38 31
[21]
liver FYN
Mean 5.84
Standard deviation 2.1
Values 8.9 4.4 5.1 5
[22]
ref_hepatocyte HCK
Mean 1.57
Standard deviation 1.7
Values 0 0 2.7 1.2 3.9
[23]
HepG2 HCK
Mean 0.0602
Standard deviation 0.085
Values 0.12 0
[24]
HepG2.C3A HCK
Mean 0.0473
Standard deviation 0.039
Values 0.019 0.075
[25]
HuH.7 HCK
Mean 0
Standard deviation 0
Values 0 0 0
[26]
SNU475 HCK
Mean 0.0747
Standard deviation 0.066
Values 0.028 0.12
[27]
THLE HCK
Mean 0.0438
Standard deviation 0.047
Values 0.077 0.011
[28]
liver HCK
Mean 3.63
Standard deviation 1.3
Values 1.7 4.2 4 4.7
[29]
ref_hepatocyte ELMO1
Mean 1.36
Standard deviation 0.9
Values 0 1.7 1.2 1.4 2.5
[30]
HepG2 ELMO1
Mean 0.0537
Standard deviation 0.021
Values 0.069 0.039
[31]
HepG2.C3A ELMO1
Mean 0.154
Standard deviation 0.025
Values 0.14 0.17
[32]
HuH.7 ELMO1
Mean 2.71
Standard deviation 1.2
Values 1.9 4.1 2.1
[33]
SNU475 ELMO1
Mean 0.213
Standard deviation 0.072
Values 0.16 0.26
[34]
THLE ELMO1
Mean 0.034
Standard deviation 0.01
Values 0.041 0.027
[35]
liver ELMO1
Mean 14
Standard deviation 5.5
Values 12 11 11 22
[36]
ref_hepatocyte CD247
Mean 0.369
Standard deviation 0.47
Values 0 0 0.22 0.51 1.1
[37]
HepG2 CD247
Mean 0.0279
Standard deviation 0.015
Values 0.017 0.039
[38]
HepG2.C3A CD247
Mean 0.0156
Standard deviation 0.0083
Values 0.0097 0.021
[39]
HuH.7 CD247
Mean 0.00526
Standard deviation 0.0048
Values 0 0.0064 0.0094
[40]
SNU475 CD247
Mean 0.0593
Standard deviation 0.038
Values 0.032 0.086
[41]
THLE CD247
Mean 0.0254
Standard deviation 0.0059
Values 0.03 0.021
[42]
liver CD247
Mean 0.518
Standard deviation 0.17
Values 0.28 0.51 0.69 0.58
[43]
ref_hepatocyte LCK
Mean 0.319
Standard deviation 0.43
Values 0.11 0 0.49 0 0.99
[44]
HepG2 LCK
Mean 4.84
Standard deviation 4.4
Values 8 1.7
[45]
HepG2.C3A LCK
Mean 4.55
Standard deviation 0.16
Values 4.4 4.7
[46]
HuH.7 LCK
Mean 0.00428
Standard deviation 0.0074
Values 0 0.013 0
[47]
SNU475 LCK
Mean 0.0173
Standard deviation 0.011
Values 0.0093 0.025
[48]
THLE LCK
Mean 0.0169
Standard deviation 0.0013
Values 0.018 0.016
[49]
liver LCK
Mean 1.07
Standard deviation 0.51
Values 1.2 0.49 1.7 0.91
[50]
ref_hepatocyte DOCK2
Mean 0.283
Standard deviation 0.4
Values 0.021 0 0.19 0.23 0.98
[51]
HepG2 DOCK2
Mean 0.0287
Standard deviation 0.041
Values 0.057 0
[52]
HepG2.C3A DOCK2
Mean 0
Standard deviation 0
Values 0 0
[53]
HuH.7 DOCK2
Mean 0.00547
Standard deviation 0.0095
Values 0.016 0 0
[54]
SNU475 DOCK2
Mean 2.92
Standard deviation 0.71
Values 2.4 3.4
[55]
THLE DOCK2
Mean 1.51
Standard deviation 0.073
Values 1.5 1.6
[56]
liver DOCK2
Mean 8.1
Standard deviation 5.9
Values 2.2 13 3.9 14