REACTOME_NEDDYLATION | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | UBB | Polyubiquitin-B | [1] | -1.49[2] | -1.73[3] | -1.54[4] | -1.91[5] | -1.58[6] | -1.02[7] |
2 | RPS27A | Ubiquitin-40S ribosomal protein S27a | [8] | [9] | [10] | [11] | [12] | [13] | [14] |
3 | UBC | Polyubiquitin-C | [15] | -1.05[16] | -0.98[17] | -1.17[18] | -1.06[19] | -1.20[20] | -0.57[21] |
4 | PSME1 | Proteasome activator complex subunit 1 | [22] | -0.82[23] | -2.57[24] | -2.14[25] | -1.78[26] | -2.42[27] | -1.52[28] |
5 | NEDD8 | NEDD8 | [29] | -1.03[30] | -2.65[31] | -2.35[32] | -2.42[33] | -2.39[34] | -2.67[35] |
6 | PSME2 | Proteasome activator complex subunit 2 | [36] | -0.64[37] | -2.19[38] | -2.23[39] | -1.56[40] | -1.96[41] | -1.15[42] |
7 | PSMA7 | Proteasome subunit alpha type-7 | [43] | 0.32[44] | 0.27[45] | -0.98[46] | 0.06[47] | -0.48[48] | -0.13[49] |
8 | PSMB1 | Proteasome subunit beta type-1 | [50] | -0.13[51] | -0.17[52] | -1.18[53] | -1.18[54] | -0.52[55] | -0.29[56] |
9 | PSMB3 | Proteasome subunit beta type-3 | [57] | -0.62[58] | -1.56[59] | -0.46[60] | -1.20[61] | -1.42[62] | -0.59[63] |
10 | PSMB4 | Proteasome subunit beta type-4 | [64] | -0.37[65] | -0.36[66] | -0.16[67] | 0.23[68] | 0.12[69] | -0.91[70] |
11 | PSMB7 | Proteasome subunit beta type-7 | [71] | -1.31[72] | -1.46[73] | -1.25[74] | -1.55[75] | -1.21[76] | -1.35[77] |
12 | PSMB5 | Proteasome subunit beta type-5 | [78] | 1.09[79] | -0.50[80] | -0.50[81] | -0.83[82] | -0.65[83] | -0.88[84] |
13 | PSMA6 | Proteasome subunit alpha type-6 | [85] | 1.21[86] | -0.22[87] | -0.22[88] | -0.30[89] | -0.38[90] | -0.79[91] |
14 | PSMA4 | Proteasome subunit alpha type-4 | [92] | -0.72[93] | -0.20[94] | -0.34[95] | 0.00[96] | -0.27[97] | -0.87[98] |
15 | SKP1 | S-phase kinase-associated protein 1 | [99] | -0.27[100] | 0.08[101] | -0.75[102] | 0.36[103] | 0.46[104] | 0.16[105] |
16 | PSMC3 | 26S proteasome regulatory subunit 6A | [106] | -0.75[107] | -0.96[108] | -0.28[109] | -1.19[110] | -1.09[111] | -0.40[112] |
17 | PSMA3 | Proteasome subunit alpha type-3 | [113] | -1.34[114] | -0.48[115] | -1.09[116] | -0.45[117] | -0.99[118] | -0.63[119] |
18 | PSMB6 | Proteasome subunit beta type-6 | [120] | -0.79[121] | -0.79[122] | -0.57[123] | -1.00[124] | -1.36[125] | -0.47[126] |
19 | PSMA2 | Proteasome subunit alpha type-2 | [127] | -0.87[128] | -0.06[129] | 0.34[130] | -0.50[131] | -0.22[132] | -0.24[133] |
20 | PSMD4 | 26S proteasome non-ATPase regulatory subunit 4 | [134] | -0.36[135] | -0.49[136] | -0.22[137] | 0.20[138] | -0.43[139] | -0.57[140] |
21 | PSMD7 | 26S proteasome non-ATPase regulatory subunit 7 | [141] | -0.44[142] | -0.21[143] | -0.28[144] | -0.88[145] | -0.51[146] | -0.74[147] |
22 | PSMD8 | 26S proteasome non-ATPase regulatory subunit 8 | [148] | -0.27[149] | -0.18[150] | 0.03[151] | -0.61[152] | 0.06[153] | -0.72[154] |
23 | UBE2D3 | Ubiquitin-conjugating enzyme E2 D3 | [155] | -0.12[156] | 0.16[157] | 0.44[158] | 0.13[159] | 0.48[160] | 0.71[161] |
24 | PSMD2 | 26S proteasome non-ATPase regulatory subunit 2 | [162] | 1.26[163] | 0.29[164] | 0.43[165] | 0.50[166] | 1.70[167] | 0.32[168] |
25 | PSMC1 | 26S proteasome regulatory subunit 4 | [169] | -0.42[170] | -0.50[171] | -1.08[172] | 0.69[173] | 0.12[174] | -0.52[175] |
26 | PSMA1 | Proteasome subunit alpha type-1 | [176] | -0.23[177] | 0.01[178] | 0.14[179] | 0.26[180] | -0.33[181] | -0.03[182] |
27 | UBA52 | Ubiquitin-60S ribosomal protein L40 | [183] | 1.39[184] | 1.25[185] | 2.34[186] | 0.34[187] | 1.03[188] | 0.20[189] |
28 | PSMC5 | 26S proteasome regulatory subunit 8 | [190] | 0.08[191] | -0.17[192] | -0.02[193] | -0.33[194] | -0.01[195] | -0.27[196] |
29 | RBX1 | E3 ubiquitin-protein ligase RBX1 | [197] | -1.35[198] | -0.96[199] | -1.03[200] | -1.84[201] | -1.53[202] | -1.25[203] |
30 | PSMD3 | 26S proteasome non-ATPase regulatory subunit 3 | [204] | 0.48[205] | -0.17[206] | 0.49[207] | 0.20[208] | 0.33[209] | -0.55[210] |
31 | PSMB8 | Proteasome subunit beta type-8 | [211] | -1.91[212] | -2.65[213] | -9.80[214] | 0.18[215] | -1.23[216] | -1.24[217] |
32 | PSMD14 | 26S proteasome non-ATPase regulatory subunit 14 | [218] | -0.34[219] | 0.12[220] | 0.44[221] | 0.07[222] | 0.00[223] | -0.70[224] |
33 | PSMC4 | 26S proteasome regulatory subunit 6B | [225] | 0.08[226] | -0.03[227] | -0.03[228] | -0.31[229] | -0.29[230] | -0.22[231] |
34 | PSMD6 | 26S proteasome non-ATPase regulatory subunit 6 | [232] | -1.07[233] | -0.73[234] | -1.75[235] | -0.93[236] | -0.22[237] | -0.81[238] |
35 | UBD | Ubiquitin D | [239] | 0.25[240] | -0.87[241] | -4.46[242] | -5.57[243] | -9.99[244] | -2.67[245] |
36 | PSMD13 | 26S proteasome non-ATPase regulatory subunit 13 | [246] | 0.13[247] | 0.10[248] | 0.66[249] | 0.13[250] | -0.46[251] | -0.62[252] |
37 | PSMD12 | 26S proteasome non-ATPase regulatory subunit 12 | [253] | -0.69[254] | -0.76[255] | -1.00[256] | -0.25[257] | -0.28[258] | -0.70[259] |
38 | COPS6 | COP9 signalosome complex subunit 6 | [260] | -0.51[261] | -0.73[262] | -0.69[263] | -0.24[264] | -0.09[265] | -0.59[266] |
39 | PSMC6 | 26S proteasome regulatory subunit 10B | [267] | -0.39[268] | 1.04[269] | -0.08[270] | 0.11[271] | -0.06[272] | -0.04[273] |
40 | PSMD11 | 26S proteasome non-ATPase regulatory subunit 11 | [274] | 0.49[275] | -0.04[276] | 0.62[277] | 0.51[278] | 0.57[279] | 0.78[280] |
41 | FBXO2 | F-box only protein 2 | [281] | 1.22[282] | 1.71[283] | -1.76[284] | -2.21[285] | -6.02[286] | -2.22[287] |
42 | PSMC2 | 26S proteasome regulatory subunit 7 | [288] | 0.24[289] | 0.50[290] | 0.34[291] | 0.91[292] | 0.64[293] | 0.83[294] |
43 | DDB1 | DNA damage-binding protein 1 | [295] | 2.32[296] | 1.64[297] | 2.82[298] | 1.71[299] | 1.62[300] | 1.45[301] |
44 | FBXW5 | F-box/WD repeat-containing protein 5 | [302] | 0.23[303] | 0.44[304] | -0.39[305] | 0.09[306] | -0.39[307] | 1.67[308] |
45 | COMMD1 | COMM domain-containing protein 1 | [309] | -1.88[310] | -2.28[311] | -3.62[312] | -2.45[313] | -2.61[314] | -1.54[315] |
46 | PSME3 | Proteasome activator complex subunit 3 | [316] | 1.47[317] | 1.04[318] | 0.79[319] | 0.93[320] | 1.11[321] | 0.40[322] |
47 | HIF1A | Hypoxia-inducible factor 1-alpha | [323] | 0.55[324] | 0.18[325] | 1.02[326] | 3.16[327] | 3.41[328] | 0.05[329] |
48 | FBXO7 | F-box only protein 7 | [330] | 0.62[331] | 1.20[332] | 0.77[333] | -0.17[334] | -0.04[335] | 0.38[336] |
49 | DCAF11 | DDB1- and CUL4-associated factor 11 | [337] | 1.35[338] | 0.89[339] | 0.99[340] | -0.80[341] | -0.97[342] | 1.43[343] |
50 | UCHL3 | Ubiquitin carboxyl-terminal hydrolase isozyme L3 | [344] | -0.68[345] | -0.75[346] | -0.80[347] | -1.33[348] | -1.72[349] | -0.78[350] |
51 | DCAF6 | DDB1- and CUL4-associated factor 6 | [351] | -0.77[352] | -0.58[353] | 0.98[354] | 0.75[355] | -0.08[356] | 1.38[357] |
52 | COMMD6 | COMM domain-containing protein 6 | [358] | -0.45[359] | 0.02[360] | 0.52[361] | -0.71[362] | -1.04[363] | -0.48[364] |
53 | COMMD3 | COMM domain-containing protein 3 | [365] | -1.80[366] | -0.96[367] | -0.86[368] | -1.34[369] | -1.19[370] | -1.08[371] |
54 | RBBP7 | Histone-binding protein RBBP7 | [372] | 0.58[373] | 0.71[374] | 0.45[375] | 1.52[376] | 2.14[377] | 0.19[378] |
55 | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1 | [379] | 1.23[380] | 1.40[381] | 1.35[382] | 1.74[383] | 1.65[384] | 1.59[385] |
56 | PSMB10 | Proteasome subunit beta type-10 | [386] | -1.49[387] | -1.04[388] | -2.86[389] | -0.47[390] | -1.73[391] | -0.56[392] |
57 | WSB2 | WD repeat and SOCS box-containing protein 2 | [393] | 0.08[394] | 0.28[395] | 0.90[396] | 0.67[397] | 0.51[398] | 0.31[399] |
58 | GPS1 | COP9 signalosome complex subunit 1 | [400] | 1.29[401] | 1.26[402] | 0.54[403] | 0.68[404] | 0.48[405] | 0.67[406] |
59 | PSMA5 | Proteasome subunit alpha type-5 | [407] | 1.56[408] | 1.84[409] | 1.47[410] | 1.79[411] | 1.26[412] | 1.43[413] |
60 | NAE1 | NEDD8-activating enzyme E1 regulatory subunit | [414] | 0.18[415] | 1.17[416] | 0.13[417] | 0.59[418] | 0.73[419] | -0.66[420] |
61 | COPS5 | COP9 signalosome complex subunit 5 | [421] | -0.57[422] | 0.23[423] | 0.49[424] | 0.71[425] | 0.14[426] | 0.37[427] |
62 | PSMF1 | Proteasome inhibitor PI31 subunit | [428] | 1.94[429] | 1.84[430] | 0.71[431] | 0.80[432] | 0.46[433] | 1.37[434] |
63 | COPS3 | COP9 signalosome complex subunit 3 | [435] | 0.39[436] | 0.45[437] | 0.93[438] | 1.02[439] | 0.94[440] | -0.28[441] |
64 | RNF7 | RING-box protein 2 | [442] | 0.52[443] | 0.70[444] | -0.22[445] | 0.06[446] | 0.00[447] | 0.12[448] |
65 | SPSB1 | SPRY domain-containing SOCS box protein 1 | [449] | -0.60[450] | -1.63[451] | -0.84[452] | 0.18[453] | -1.46[454] | -0.33[455] |
66 | UBE2M | NEDD8-conjugating enzyme Ubc12 | [456] | 0.06[457] | -0.26[458] | 0.46[459] | 0.41[460] | 0.19[461] | -1.84[462] |
67 | COPS7A | COP9 signalosome complex subunit 7a | [463] | 0.24[464] | 0.63[465] | 0.50[466] | 0.14[467] | 0.37[468] | 0.43[469] |
68 | BTBD1 | BTB/POZ domain-containing protein 1 | [470] | 0.47[471] | 0.73[472] | 0.46[473] | 1.19[474] | 1.10[475] | 0.78[476] |
69 | PSMB2 | Proteasome subunit beta type-2 | [477] | 1.72[478] | 1.31[479] | 1.76[480] | 2.10[481] | 1.98[482] | 1.91[483] |
70 | COMMD4 | COMM domain-containing protein 4 | [484] | 0.29[485] | -0.10[486] | 0.24[487] | -0.03[488] | 0.76[489] | -0.51[490] |
71 | SPSB3 | SPRY domain-containing SOCS box protein 3 | [491] | -1.43[492] | -0.66[493] | -1.09[494] | -1.73[495] | -1.19[496] | 0.57[497] |
72 | CUL4A | Cullin-4A | [498] | 0.94[499] | 1.18[500] | 0.53[501] | 0.80[502] | 0.48[503] | 1.43[504] |
73 | UBE2F | NEDD8-conjugating enzyme UBE2F | [505] | -0.48[506] | -0.23[507] | -1.82[508] | -0.84[509] | -0.50[510] | -0.06[511] |
74 | COMMD7 | COMM domain-containing protein 7 | [512] | 0.71[513] | 0.68[514] | -1.45[515] | 0.81[516] | -0.28[517] | -0.01[518] |
75 | PSMB9 | Proteasome subunit beta type-9 | [519] | -2.29[520] | -5.05[521] | -7.29[522] | 1.35[523] | -1.02[524] | -0.98[525] |
76 | COPS2 | COP9 signalosome complex subunit 2 | [526] | -0.12[527] | 1.82[528] | 2.09[529] | 1.18[530] | 1.28[531] | 0.45[532] |
77 | KEAP1 | Kelch-like ECH-associated protein 1 | [533] | 0.92[534] | 0.78[535] | 0.56[536] | 0.05[537] | 0.92[538] | 1.40[539] |
78 | PSMD9 | 26S proteasome non-ATPase regulatory subunit 9 | [540] | 0.09[541] | 0.44[542] | -0.48[543] | -0.03[544] | 0.31[545] | 0.24[546] |
79 | DCAF8 | DDB1- and CUL4-associated factor 8 | [547] | 1.05[548] | 1.25[549] | 1.22[550] | 1.41[551] | 0.88[552] | 2.76[553] |
80 | CUL1 | Cullin-1 | [554] | 0.32[555] | 0.96[556] | 0.56[557] | 1.45[558] | 0.98[559] | 1.60[560] |
81 | LMO7 | LIM domain only protein 7 | [561] | 0.81[562] | 1.81[563] | 1.43[564] | -0.75[565] | -0.18[566] | 1.38[567] |
82 | FBXL5 | F-box/LRR-repeat protein 5 | [568] | -0.74[569] | -0.89[570] | 0.83[571] | 0.76[572] | 0.33[573] | 2.02[574] |
83 | EPAS1 | Endothelial PAS domain-containing protein 1 | [575] | 3.42[576] | 2.58[577] | 2.29[578] | 0.30[579] | 3.19[580] | 2.78[581] |
84 | DCAF13 | DDB1- and CUL4-associated factor 13 | [582] | 0.68[583] | 1.54[584] | 0.83[585] | 1.52[586] | 0.43[587] | 0.21[588] |
85 | WDR5 | WD repeat-containing protein 5 | [589] | 0.99[590] | 0.91[591] | 0.31[592] | 0.59[593] | 0.86[594] | 0.37[595] |
86 | COMMD5 | COMM domain-containing protein 5 | [596] | -0.03[597] | 0.12[598] | -1.10[599] | -0.57[600] | -0.47[601] | -0.33[602] |
87 | SOCS3 | Suppressor of cytokine signaling 3 | [603] | -3.43[604] | -3.89[605] | -2.12[606] | 0.07[607] | -1.13[608] | 0.99[609] |
88 | UBE2D2 | Ubiquitin-conjugating enzyme E2 D2 | [610] | 1.71[611] | 1.71[612] | 1.04[613] | 1.66[614] | 1.74[615] | 0.82[616] |
89 | NUB1 | NEDD8 ultimate buster 1 | [617] | 0.43[618] | 0.43[619] | 1.09[620] | 1.41[621] | 0.98[622] | 0.92[623] |
90 | UBA3 | NEDD8-activating enzyme E1 catalytic subunit | [624] | 0.44[625] | 0.95[626] | 0.08[627] | 1.05[628] | 1.55[629] | 0.68[630] |
91 | PSMD10 | 26S proteasome non-ATPase regulatory subunit 10 | [631] | 0.65[632] | 0.83[633] | 0.92[634] | 1.64[635] | 0.87[636] | 0.23[637] |
92 | LRRC41 | Leucine-rich repeat-containing protein 41 | [638] | 1.86[639] | 1.75[640] | 1.02[641] | 2.06[642] | 1.75[643] | 1.58[644] |
93 | FBXO11 | F-box only protein 11 | [645] | 0.26[646] | 0.92[647] | 0.26[648] | 1.13[649] | 1.04[650] | 0.98[651] |
94 | COPS4 | COP9 signalosome complex subunit 4 | [652] | 0.18[653] | 1.12[654] | 1.06[655] | 0.69[656] | 0.81[657] | 0.41[658] |
95 | WSB1 | WD repeat and SOCS box-containing protein 1 | [659] | 1.48[660] | 2.23[661] | 2.21[662] | 1.87[663] | 1.29[664] | 2.01[665] |
96 | COPS8 | COP9 signalosome complex subunit 8 | [666] | 1.40[667] | 1.30[668] | 0.69[669] | 1.86[670] | 2.72[671] | 0.77[672] |
97 | FBXO6 | F-box only protein 6 | [673] | -1.55[674] | 0.05[675] | -1.79[676] | -1.07[677] | -3.30[678] | -0.47[679] |
98 | FBXO17 | F-box only protein 17 | [680] | 1.13[681] | 1.79[682] | 0.24[683] | 0.64[684] | -0.13[685] | 1.04[686] |
99 | PUM2 | Pumilio homolog 2 | [687] | 1.98[688] | 3.07[689] | 2.76[690] | 2.33[691] | 2.28[692] | 2.98[693] |
100 | PSME4 | Proteasome activator complex subunit 4 | [694] | 2.18[695] | 2.94[696] | 3.01[697] | 2.20[698] | 2.07[699] | 2.49[700] |
101 | ASB13 | Ankyrin repeat and SOCS box protein 13 | [701] | 0.23[702] | 0.27[703] | -0.24[704] | 0.20[705] | -0.38[706] | 2.39[707] |
102 | BTBD6 | BTB/POZ domain-containing protein 6 | [708] | -7.93[709] | -8.32[710] | -0.93[711] | 0.75[712] | 1.14[713] | -0.23[714] |
103 | FBXO22 | F-box only protein 22 | [715] | 1.66[716] | 1.27[717] | 0.78[718] | 0.55[719] | 0.27[720] | 0.96[721] |
104 | OBSL1 | Obscurin-like protein 1 | [722] | 2.53[723] | 3.42[724] | 2.04[725] | 1.83[726] | 0.99[727] | 1.54[728] |
105 | KLHL5 | Kelch-like protein 5 | [729] | 1.99[730] | 2.03[731] | 1.67[732] | 2.34[733] | 2.84[734] | 2.71[735] |
106 | BIRC5 | Baculoviral IAP repeat-containing protein 5 | [736] | 2.28[737] | 2.69[738] | 2.69[739] | 1.55[740] | 2.26[741] | -1.46[742] |
107 | DCUN1D1 | DCN1-like protein 1 | [743] | -0.25[744] | 0.95[745] | 1.04[746] | 0.85[747] | 0.92[748] | 2.00[749] |
108 | DCUN1D4 | DCN1-like protein 4 | [750] | 0.38[751] | 1.72[752] | 2.95[753] | 1.67[754] | 1.52[755] | 2.33[756] |
109 | DCAF7 | DDB1- and CUL4-associated factor 7 | [757] | 2.56[758] | 3.38[759] | 3.40[760] | 2.74[761] | 2.50[762] | 2.22[763] |
110 | COMMD1 | COMM domain-containing protein 10 | [764] | -0.04[765] | 0.32[766] | -0.84[767] | 0.51[768] | 0.00[769] | 0.55[770] |
111 | CUL4B | Cullin-4B | [771] | 0.61[772] | 1.96[773] | 3.48[774] | 3.18[775] | 3.99[776] | 1.73[777] |
112 | KLHL21 | Kelch-like protein 21 | [778] | 2.34[779] | 2.50[780] | 1.30[781] | 1.46[782] | 1.93[783] | 1.95[784] |
113 | DDB2 | DNA damage-binding protein 2 | [785] | 1.79[786] | 1.27[787] | 0.00[788] | -0.74[789] | -0.28[790] | -0.67[791] |
114 | ASB8 | Ankyrin repeat and SOCS box protein 8 | [792] | -0.50[793] | 0.21[794] | 0.11[795] | 0.64[796] | 0.14[797] | 1.43[798] |
115 | PSMD5 | 26S proteasome non-ATPase regulatory subunit 5 | [799] | 1.07[800] | 0.48[801] | 2.10[802] | 2.03[803] | 2.01[804] | 1.67[805] |
116 | KLHL2 | Kelch-like protein 2 | [806] | -0.41[807] | 0.36[808] | -0.63[809] | 0.04[810] | 0.57[811] | 1.75[812] |
117 | CAND1 | Cullin-associated NEDD8-dissociated protein 1 | [813] | 2.31[814] | 3.39[815] | 3.59[816] | 3.63[817] | 3.61[818] | 3.25[819] |
118 | CUL3 | Cullin-3 | [820] | 1.32[821] | 2.19[822] | 1.96[823] | 2.33[824] | 2.30[825] | 1.80[826] |
119 | FBXW11 | F-box/WD repeat-containing protein 11 | [827] | 2.08[828] | 1.95[829] | 2.75[830] | 2.39[831] | 2.18[832] | 1.80[833] |
120 | FBXO9 | F-box only protein 9 | [834] | 1.79[835] | 1.72[836] | 1.36[837] | 2.40[838] | 1.61[839] | 1.96[840] |
121 | FBXL3 | F-box/LRR-repeat protein 3 | [841] | -0.09[842] | 0.47[843] | 1.46[844] | 1.01[845] | 1.19[846] | 2.09[847] |
122 | FEM1A | Protein fem-1 homolog A | [848] | 1.38[849] | 0.89[850] | 1.53[851] | 0.21[852] | 1.12[853] | 1.83[854] |
123 | DDA1 | DET1- and DDB1-associated protein 1 | [855] | 1.46[856] | 1.19[857] | 1.93[858] | 0.85[859] | 1.42[860] | 1.29[861] |
124 | COMMD9 | COMM domain-containing protein 9 | [862] | 1.03[863] | 0.81[864] | 1.24[865] | 1.08[866] | 0.53[867] | 1.50[868] |
125 | VHL | von Hippel-Lindau disease tumor suppressor | [869] | 2.66[870] | 2.73[871] | 3.55[872] | 1.71[873] | 2.28[874] | 1.83[875] |
126 | FBXO31 | F-box only protein 31 | [876] | 2.81[877] | 2.98[878] | 1.70[879] | 0.87[880] | 0.97[881] | 2.07[882] |
127 | COPS7B | COP9 signalosome complex subunit 7b | [883] | 1.66[884] | 2.01[885] | 1.98[886] | 1.48[887] | 1.40[888] | 0.22[889] |
128 | FBXW4 | F-box/WD repeat-containing protein 4 | [890] | 1.39[891] | 1.72[892] | 0.09[893] | -0.19[894] | 0.52[895] | 0.92[896] |
129 | CUL2 | Cullin-2 | [897] | 0.81[898] | 2.18[899] | 2.38[900] | 3.32[901] | 2.56[902] | 1.85[903] |
130 | CISH | Cytokine-inducible SH2-containing protein | [904] | -2.20[905] | -2.06[906] | -1.80[907] | -1.78[908] | -3.34[909] | 1.95[910] |
131 | COMMD2 | COMM domain-containing protein 2 | [911] | 0.90[912] | 1.67[913] | 1.40[914] | 1.86[915] | 1.67[916] | 0.99[917] |
132 | FBXL15 | F-box/LRR-repeat protein 15 | [918] | 0.36[919] | 2.46[920] | 0.94[921] | -0.06[922] | 0.34[923] | 1.01[924] |
133 | FEM1B | Protein fem-1 homolog B | [925] | -0.22[926] | 0.59[927] | 2.26[928] | 1.06[929] | 0.95[930] | 2.16[931] |
134 | DCUN1D5 | DCN1-like protein 5 | [932] | 2.25[933] | 2.02[934] | 1.89[935] | 2.92[936] | 2.42[937] | 1.39[938] |
135 | DCAF4 | DDB1- and CUL4-associated factor 4 | [939] | 1.52[940] | 1.92[941] | -0.16[942] | -0.14[943] | -0.23[944] | 0.20[945] |
136 | RBBP5 | Retinoblastoma-binding protein 5 | [946] | 1.49[947] | 0.89[948] | 1.80[949] | 2.43[950] | 1.91[951] | 1.98[952] |
137 | COMMD8 | COMM domain-containing protein 8 | [953] | -0.26[954] | 0.69[955] | 1.59[956] | 1.73[957] | 0.86[958] | 1.07[959] |
138 | DCAF5 | DDB1- and CUL4-associated factor 5 | [960] | 1.65[961] | 2.50[962] | 1.70[963] | 2.58[964] | 2.30[965] | 2.57[966] |
139 | CCDC22 | Coiled-coil domain-containing protein 22 | [967] | 0.66[968] | 0.99[969] | -0.79[970] | 0.87[971] | 0.22[972] | 0.36[973] |
140 | SOCS6 | Suppressor of cytokine signaling 6 | [974] | 1.07[975] | 1.88[976] | 0.96[977] | 2.20[978] | 1.69[979] | 2.68[980] |
141 | SOCS2 | Suppressor of cytokine signaling 2 | [981] | -0.10[982] | -2.68[983] | -4.39[984] | 1.52[985] | -4.32[986] | 2.50[987] |
142 | FBXO4 | F-box only protein 4 | [988] | -0.91[989] | 0.21[990] | 1.18[991] | 0.35[992] | -0.83[993] | 0.31[994] |
143 | SKP2 | S-phase kinase-associated protein 2 | [995] | 2.02[996] | 2.44[997] | 3.62[998] | 2.13[999] | 2.09[1000] | 1.93[1001] |
144 | CUL5 | Cullin-5 | [1002] | 1.28[1003] | 2.73[1004] | 2.26[1005] | 3.39[1006] | 2.41[1007] | 3.18[1008] |
145 | FBXW2 | F-box/WD repeat-containing protein 2 | [1009] | 3.14[1010] | 2.77[1011] | 3.81[1012] | 2.91[1013] | 3.37[1014] | 3.73[1015] |
146 | FBXW7 | F-box/WD repeat-containing protein 7 | [1016] | -0.03[1017] | 0.60[1018] | 0.63[1019] | -0.03[1020] | 0.86[1021] | 2.00[1022] |
147 | FBXL12 | F-box/LRR-repeat protein 12 | [1023] | 1.26[1024] | 1.36[1025] | 1.65[1026] | 0.66[1027] | 0.49[1028] | 1.08[1029] |
148 | FEM1C | Protein fem-1 homolog C | [1030] | 0.41[1031] | 1.60[1032] | 1.66[1033] | 1.89[1034] | 2.50[1035] | 2.44[1036] |
149 | KCTD6 | BTB/POZ domain-containing protein KCTD6 | [1037] | -0.84[1038] | 0.38[1039] | 0.87[1040] | -1.63[1041] | 0.27[1042] | 1.01[1043] |
150 | KLHL9 | Kelch-like protein 9 | [1044] | 1.93[1045] | 2.26[1046] | 1.80[1047] | 2.59[1048] | 2.38[1049] | 3.01[1050] |
151 | FBXO21 | F-box only protein 21 | [1051] | 2.39[1052] | 2.44[1053] | 1.99[1054] | 1.92[1055] | 2.81[1056] | 3.59[1057] |
152 | DCUN1D3 | DCN1-like protein 3 | [1058] | 1.42[1059] | 0.52[1060] | 0.75[1061] | 0.35[1062] | 0.74[1063] | 1.88[1064] |
153 | SPSB2 | SPRY domain-containing SOCS box protein 2 | [1065] | -0.40[1066] | 0.11[1067] | 1.69[1068] | 0.43[1069] | -0.30[1070] | -0.70[1071] |
154 | FBXO44 | F-box only protein 44 | [1072] | 2.05[1073] | 3.13[1074] | 0.99[1075] | 1.57[1076] | 1.11[1077] | 1.27[1078] |
155 | ASB9 | Ankyrin repeat and SOCS box protein 9 | [1079] | -0.67[1080] | 0.85[1081] | 0.81[1082] | -1.17[1083] | -4.98[1084] | -0.10[1085] |
156 | FBXL4 | F-box/LRR-repeat protein 4 | [1086] | 0.93[1087] | 1.40[1088] | 1.30[1089] | 1.21[1090] | 1.03[1091] | 2.58[1092] |
157 | LRR1 | Leucine-rich repeat protein 1 | [1093] | 0.78[1094] | 1.12[1095] | 1.95[1096] | 1.41[1097] | 1.93[1098] | 0.15[1099] |
158 | KLHL25 | Kelch-like protein 25 | [1100] | 0.92[1101] | 0.70[1102] | 0.01[1103] | -0.04[1104] | 0.12[1105] | 3.11[1106] |
159 | ASB6 | Ankyrin repeat and SOCS box protein 6 | [1107] | 1.57[1108] | 1.45[1109] | 1.65[1110] | 2.31[1111] | 2.93[1112] | 1.51[1113] |
160 | WDTC1 | WD and tetratricopeptide repeats protein 1 | [1114] | 2.24[1115] | 1.72[1116] | 2.37[1117] | 3.04[1118] | 2.78[1119] | 2.72[1120] |
161 | UBE2D1 | Ubiquitin-conjugating enzyme E2 D1 | [1121] | 1.50[1122] | 2.33[1123] | 2.72[1124] | 2.39[1125] | 2.03[1126] | 1.35[1127] |
162 | FBXO30 | F-box only protein 30 | [1128] | 1.53[1129] | 1.97[1130] | 2.32[1131] | 3.47[1132] | 2.46[1133] | 1.86[1134] |
163 | DCAF16 | DDB1- and CUL4-associated factor 16 | [1135] | 2.38[1136] | 2.79[1137] | 3.65[1138] | 2.67[1139] | 2.30[1140] | 1.25[1141] |
164 | ASB1 | Ankyrin repeat and SOCS box protein 1 | [1142] | 3.10[1143] | 3.36[1144] | 2.69[1145] | 2.61[1146] | 3.99[1147] | 1.77[1148] |
165 | ZBTB16 | Zinc finger and BTB domain-containing protein 16 | [1149] | -8.76[1150] | -9.19[1151] | -0.02[1152] | [1153] | 1.31[1154] | 4.74[1155] |
166 | SOCS5 | Suppressor of cytokine signaling 5 | [1156] | 1.50[1157] | 2.63[1158] | 2.16[1159] | 3.15[1160] | 2.39[1161] | 1.94[1162] |
167 | DCAF10 | DDB1- and CUL4-associated factor 10 | [1163] | 1.84[1164] | 2.61[1165] | 4.00[1166] | 2.13[1167] | 2.76[1168] | 3.78[1169] |
168 | FBXO27 | F-box only protein 27 | [1170] | -1.83[1171] | -1.65[1172] | 0.16[1173] | -0.83[1174] | -0.23[1175] | 0.20[1176] |
169 | DCUN1D2 | DCN1-like protein 2 | [1177] | 0.92[1178] | 1.51[1179] | 0.96[1180] | 1.27[1181] | 1.59[1182] | 1.33[1183] |
170 | BTRC | F-box/WD repeat-containing protein 1A | [1184] | 2.12[1185] | 2.87[1186] | 2.53[1187] | 1.62[1188] | 2.04[1189] | 2.20[1190] |
171 | FBXW9 | F-box/WD repeat-containing protein 9 | [1191] | 0.74[1192] | 1.13[1193] | 1.79[1194] | 0.13[1195] | 0.47[1196] | 0.15[1197] |
172 | ASB3 | Ankyrin repeat and SOCS box protein 3 | [1198] | -1.92[1199] | -1.41[1200] | -0.82[1201] | -1.37[1202] | -1.46[1203] | -0.85[1204] |
173 | ERCC8 | DNA excision repair protein ERCC-8 | [1205] | 1.49[1206] | 2.57[1207] | 1.76[1208] | 0.45[1209] | 1.64[1210] | 0.91[1211] |
174 | CUL7 | Cullin-7 | [1212] | 4.42[1213] | 4.62[1214] | 3.05[1215] | 4.22[1216] | 2.33[1217] | 2.62[1218] |
175 | KLHL22 | Kelch-like protein 22 | [1219] | 1.60[1220] | 1.34[1221] | 1.21[1222] | 1.81[1223] | 1.77[1224] | 1.28[1225] |
176 | ASB7 | Ankyrin repeat and SOCS box protein 7 | [1226] | 1.55[1227] | 1.89[1228] | 1.86[1229] | 1.93[1230] | 2.15[1231] | 2.59[1232] |
177 | DCAF17 | DDB1- and CUL4-associated factor 17 | [1233] | 1.96[1234] | 3.46[1235] | 2.23[1236] | 2.27[1237] | 2.17[1238] | 2.04[1239] |
178 | KLHL20 | Kelch-like protein 20 | [1240] | 1.18[1241] | 1.16[1242] | 1.10[1243] | 2.99[1244] | 2.37[1245] | 2.54[1246] |
179 | ANKRD9 | Ankyrin repeat domain-containing protein 9 | [1247] | 1.22[1248] | 1.47[1249] | 0.53[1250] | 1.75[1251] | 0.92[1252] | 0.46[1253] |
180 | KBTBD7 | Kelch repeat and BTB domain-containing protein 7 | [1254] | -0.18[1255] | 0.33[1256] | 1.73[1257] | 0.25[1258] | -1.00[1259] | 2.41[1260] |
181 | KBTBD6 | Kelch repeat and BTB domain-containing protein 6 | [1261] | 1.58[1262] | 1.80[1263] | 2.16[1264] | 1.43[1265] | 1.72[1266] | 2.25[1267] |
182 | UBXN7 | UBX domain-containing protein 7 | [1268] | 2.17[1269] | 2.21[1270] | 3.54[1271] | 3.06[1272] | 3.34[1273] | 3.12[1274] |
183 | TULP4 | Tubby-related protein 4 | [1275] | 2.95[1276] | 2.94[1277] | 2.76[1278] | 2.78[1279] | 2.58[1280] | 4.00[1281] |
184 | DTL | Denticleless protein homolog | [1282] | 2.94[1283] | 2.68[1284] | 3.65[1285] | 4.01[1286] | 3.79[1287] | -0.44[1288] |
185 | FBXW8 | F-box/WD repeat-containing protein 8 | [1289] | 1.58[1290] | 2.30[1291] | 3.05[1292] | 1.89[1293] | 1.39[1294] | 2.30[1295] |
186 | FBXO10 | F-box only protein 10 | [1296] | 2.20[1297] | 1.20[1298] | 3.17[1299] | 2.17[1300] | 2.15[1301] | 2.50[1302] |
187 | FBXL20 | F-box/LRR-repeat protein 20 | [1303] | 3.05[1304] | 2.58[1305] | 3.23[1306] | 3.20[1307] | 2.84[1308] | 3.76[1309] |
188 | FBXL18 | F-box/LRR-repeat protein 18 | [1310] | 3.20[1311] | 1.91[1312] | 3.49[1313] | 3.21[1314] | 3.70[1315] | 2.95[1316] |
189 | FBXL14 | F-box/LRR-repeat protein 14 | [1317] | 1.62[1318] | 1.28[1319] | 1.88[1320] | 1.51[1321] | 1.26[1322] | 1.26[1323] |
190 | NEURL2 | Neuralized-like protein 2 | [1324] | 1.38[1325] | 1.24[1326] | 0.20[1327] | -0.60[1328] | -0.41[1329] | 2.09[1330] |
191 | FBXL8 | F-box/LRR-repeat protein 8 | [1331] | 0.22[1332] | 0.89[1333] | 0.38[1334] | 0.70[1335] | -0.07[1336] | 1.01[1337] |
192 | CUL9 | Cullin-9 | [1338] | 3.94[1339] | 3.43[1340] | 2.76[1341] | 4.35[1342] | 3.36[1343] | 3.94[1344] |
193 | FBXL19 | F-box/LRR-repeat protein 19 | [1345] | 4.24[1346] | 3.75[1347] | 3.94[1348] | 3.30[1349] | 3.43[1350] | 0.75[1351] |
194 | SENP8 | Sentrin-specific protease 8 | [1352] | 0.08[1353] | 0.76[1354] | 0.54[1355] | 0.71[1356] | 0.71[1357] | 0.46[1358] |
195 | CCNF | Cyclin-F | [1359] | 3.92[1360] | 3.91[1361] | 4.84[1362] | 4.11[1363] | 4.95[1364] | 2.05[1365] |
196 | KLHL11 | Kelch-like protein 11 | [1366] | 0.44[1367] | -0.13[1368] | 1.52[1369] | 0.84[1370] | 1.33[1371] | 3.42[1372] |
197 | KLHL13 | Kelch-like protein 13 | [1373] | 1.70[1374] | -3.97[1375] | 4.55[1376] | 0.49[1377] | 1.20[1378] | 2.14[1379] |
198 | KCTD7 | BTB/POZ domain-containing protein KCTD7 | [1380] | 3.37[1381] | 4.02[1382] | 4.17[1383] | 4.66[1384] | 3.07[1385] | 2.65[1386] |
199 | KBTBD8 | Kelch repeat and BTB domain-containing protein 8 | [1387] | 1.35[1388] | 2.20[1389] | 0.33[1390] | -0.54[1391] | 1.89[1392] | 1.18[1393] |
200 | GAN | Gigaxonin | [1394] | 1.82[1395] | 1.41[1396] | 2.53[1397] | 1.78[1398] | 2.34[1399] | 3.47[1400] |
201 | FBXO32 | F-box only protein 32 | [1401] | 0.16[1402] | -0.55[1403] | 0.72[1404] | 7.52[1405] | 6.74[1406] | 2.80[1407] |
202 | FBXO15 | F-box only protein 15 | [1408] | -3.30[1409] | -4.97[1410] | -3.43[1411] | 0.65[1412] | -2.20[1413] | -0.62[1414] |
203 | FBXO41 | F-box only protein 41 | [1415] | 5.65[1416] | 6.05[1417] | 3.65[1418] | 3.86[1419] | 4.84[1420] | 1.52[1421] |
204 | HIF3A | Hypoxia-inducible factor 3-alpha | [1422] | -0.22[1423] | 0.27[1424] | -2.35[1425] | -1.06[1426] | -1.28[1427] | 4.44[1428] |
205 | FBXL22 | F-box and leucine-rich protein 22 | [1429] | -1.16[1430] | 1.28[1431] | 0.06[1432] | -1.69[1433] | -1.31[1434] | -0.68[1435] |
206 | FBXL13 | F-box/LRR-repeat protein 13 | [1436] | 0.28[1437] | 0.73[1438] | -0.23[1439] | 2.41[1440] | 0.59[1441] | 1.83[1442] |
207 | KLHL3 | Kelch-like protein 3 | [1443] | 1.68[1444] | -3.61[1445] | 0.13[1446] | 1.88[1447] | 4.13[1448] | 5.46[1449] |
208 | CCDC8 | Coiled-coil domain-containing protein 8 | [1450] | -2.09[1451] | 5.11[1452] | 1.01[1453] | 6.53[1454] | 3.36[1455] | 1.38[1456] |
209 | FBXL7 | F-box/LRR-repeat protein 7 | [1457] | -4.21[1458] | -3.41[1459] | -3.97[1460] | 0.34[1461] | 6.43[1462] | 2.85[1463] |
210 | ASB4 | Ankyrin repeat and SOCS box protein 4 | [1464] | 4.33[1465] | 2.79[1466] | 1.00[1467] | -0.91[1468] | -2.03[1469] | 1.25[1470] |
211 | ASB16 | Ankyrin repeat and SOCS box protein 16 | [1471] | 1.74[1472] | 2.63[1473] | 0.99[1474] | 2.55[1475] | 2.23[1476] | 1.61[1477] |
212 | ASB2 | Ankyrin repeat and SOCS box protein 2 | [1478] | 6.28[1479] | 5.11[1480] | -2.73[1481] | 2.68[1482] | -2.09[1483] | 1.17[1484] |
213 | FBXL16 | F-box/LRR-repeat protein 16 | [1485] | 4.52[1486] | 5.03[1487] | 4.32[1488] | 1.07[1489] | 0.59[1490] | -0.15[1491] |
214 | FBXW10 | F-box/WD repeat-containing protein 10 | [1492] | -3.12[1493] | -3.33[1494] | 2.38[1495] | 4.45[1496] | -0.80[1497] | 2.14[1498] |
215 | ASB11 | Ankyrin repeat and SOCS box protein 11 | [1499] | -1.51[1500] | 0.24[1501] | 0.02[1502] | -1.02[1503] | -0.53[1504] | -0.53[1505] |
216 | SPSB4 | SPRY domain-containing SOCS box protein 4 | [1506] | -2.77[1507] | [1508] | [1509] | 6.09[1510] | -0.10[1511] | 2.89[1512] |
217 | ASB14 | Ankyrin repeat and SOCS box protein 14 | [1513] | 0.54[1514] | 2.11[1515] | 0.76[1516] | 1.80[1517] | 1.73[1518] | 3.70[1519] |
218 | FBXO40 | F-box only protein 40 | [1520] | 3.86[1521] | 4.99[1522] | 4.72[1523] | 3.92[1524] | 3.61[1525] | 4.96[1526] |
219 | ASB10 | Ankyrin repeat and SOCS box protein 10 | [1527] | [1528] | [1529] | [1530] | [1531] | [1532] | [1533] |
220 | ASB17 | Ankyrin repeat and SOCS box protein 17 | [1534] | [1535] | [1536] | [1537] | [1538] | [1539] | [1540] |
221 | PSMB11 | Proteasome subunit beta type-11 | [1541] | [1542] | [1543] | [1544] | [1545] | [1546] | [1547] |
222 | KLHL42 | Kelch-like protein 42 | [1548] | [1549] | [1550] | [1551] | [1552] | [1553] | [1554] |
223 | KLHL41 | Kelch-like protein 41 | [1555] | [1556] | [1557] | [1558] | [1559] | [1560] | [1561] |
224 | ASB12 | Ankyrin repeat and SOCS box protein 12 | [1562] | [1563] | [1564] | [1565] | [1566] | [1567] | [1568] |
225 | ELOB | Elongin-B | [1569] | [1570] | [1571] | [1572] | [1573] | [1574] | [1575] |
226 | ELOC | Elongin-C | [1576] | [1577] | [1578] | [1579] | [1580] | [1581] | [1582] |
227 | KBTBD13 | Kelch repeat and BTB domain-containing protein 13 | [1583] | [1584] | [1585] | [1586] | [1587] | [1588] | [1589] |
228 | ASB5 | Ankyrin repeat and SOCS box protein 5 | [1590] | [1591] | [1592] | [1593] | [1594] | [1595] | [1596] |
229 | FBXW12 | F-box/WD repeat-containing protein 12 | [1597] | [1598] | [1599] | [1600] | [1601] | [1602] | [1603] |
230 | SEM1 | Putative protein SEM1, isoform 2 | [1604] | [1605] | [1606] | [1607] | [1608] | [1609] | [1610] |
231 | COP1 | [1611] | [1612] | [1613] | [1614] | [1615] | [1616] | [1617] | |
232 | ASB15 | Ankyrin repeat and SOCS box protein 15 | [1618] | [1619] | [1620] | [1621] | [1622] | [1623] | [1624] |
233 | PSMA8 | Proteasome subunit alpha type-7-like | [1625] | [1626] | [1627] | [1628] | [1629] | [1630] | [1631] |
234 | ASB18 | Ankyrin repeat and SOCS box protein 18 | [1632] | [1633] | [1634] | [1635] | [1636] | [1637] | [1638] |