REACTOME_MUCOPOLYSACCHARIDOSES Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 HYAL1 Hyaluronidase-1 [1] -0.88[2] -0.33[3] -6.07[4] -9.10[5] -6.92[6] -0.72[7]
2 GUSB Beta-glucuronidase [8] -1.98[9] -1.38[10] -0.82[11] -0.77[12] -1.30[13] -0.30[14]
3 GLB1 Beta-galactosidase [15] 0.28[16] 0.21[17] 1.30[18] -0.40[19] 0.36[20] -0.41[21]
4 NAGLU Alpha-N-acetylglucosaminidase [22] -0.23[23] -0.24[24] 0.26[25] -0.93[26] -1.26[27] -0.79[28]
5 GNS N-acetylglucosamine-6-sulfatase [29] 1.41[30] 1.35[31] 2.16[32] 2.27[33] 2.51[34] 1.71[35]
6 IDS Iduronate 2-sulfatase [36] -0.16[37] -0.42[38] -0.93[39] 2.13[40] 1.27[41] 0.66[42]
7 HGSNAT Heparan-alpha-glucosaminide N-acetyltransferase [43] 0.11[44] 0.22[45] 0.55[46] 0.71[47] 0.70[48] 0.70[49]
8 SGSH N-sulphoglucosamine sulphohydrolase [50] 1.36[51] 0.88[52] -0.58[53] 0.32[54] 0.38[55] -0.06[56]
9 GALNS N-acetylgalactosamine-6-sulfatase [57] 1.23[58] 0.64[59] 0.74[60] 0.79[61] 0.87[62] 0.25[63]
10 ARSB Arylsulfatase B [64] 3.26[65] 2.16[66] 1.58[67] 1.62[68] 2.09[69] 1.62[70]
11 IDUA Alpha-L-iduronidase [71] -2.77[72] -1.91[73] -1.48[74] 0.85[75] -0.85[76] -0.45[77]
[1]
ref_hepatocyte HYAL1
Mean 53.9
Standard deviation 39
Values 18 24 36 90 1e+02
[2]
HepG2 HYAL1
Mean 83.6
Standard deviation 4.4
Values 81 87
[3]
HepG2.C3A HYAL1
Mean 88.6
Standard deviation 33
Values 1.1e+02 65
[4]
HuH.7 HYAL1
Mean 1.54
Standard deviation 0.96
Values 0.95 2.7 1
[5]
SNU475 HYAL1
Mean 0.168
Standard deviation 0.058
Values 0.21 0.13
[6]
THLE HYAL1
Mean 0.868
Standard deviation 0.069
Values 0.92 0.82
[7]
liver HYAL1
Mean 66.7
Standard deviation 12
Values 80 54 73 59
[8]
ref_hepatocyte GUSB
Mean 25.3
Standard deviation 23
Values 7 7.5 11 52 49
[9]
HepG2 GUSB
Mean 18.3
Standard deviation 3.5
Values 21 16
[10]
HepG2.C3A GUSB
Mean 20.1
Standard deviation 2
Values 22 19
[11]
HuH.7 GUSB
Mean 27.5
Standard deviation 3.9
Values 26 25 32
[12]
SNU475 GUSB
Mean 25.3
Standard deviation 2.9
Values 23 27
[13]
THLE GUSB
Mean 20
Standard deviation 0.097
Values 20 20
[14]
liver GUSB
Mean 42.1
Standard deviation 30
Values 54 22 79 14
[15]
ref_hepatocyte GLB1
Mean 15.3
Standard deviation 5.7
Values 22 9.9 8.6 18 18
[16]
HepG2 GLB1
Mean 53.1
Standard deviation 4.7
Values 56 50
[17]
HepG2.C3A GLB1
Mean 36.7
Standard deviation 8.2
Values 42 31
[18]
HuH.7 GLB1
Mean 72.4
Standard deviation 9.9
Values 62 81 75
[19]
SNU475 GLB1
Mean 19.7
Standard deviation 1.4
Values 19 21
[20]
THLE GLB1
Mean 38.2
Standard deviation 4.9
Values 35 42
[21]
liver GLB1
Mean 23.6
Standard deviation 8.2
Values 23 20 35 16
[22]
ref_hepatocyte NAGLU
Mean 11.6
Standard deviation 11
Values 4.4 2.3 5.1 22 24
[23]
HepG2 NAGLU
Mean 28.5
Standard deviation 0.22
Values 28 29
[24]
HepG2.C3A NAGLU
Mean 20.4
Standard deviation 4
Values 23 18
[25]
HuH.7 NAGLU
Mean 26.8
Standard deviation 6.6
Values 26 20 34
[26]
SNU475 NAGLU
Mean 10.4
Standard deviation 3.9
Values 13 7.6
[27]
THLE NAGLU
Mean 9.46
Standard deviation 2.1
Values 7.9 11
[28]
liver NAGLU
Mean 13.8
Standard deviation 2.3
Values 16 11 15 14
[29]
ref_hepatocyte GNS
Mean 10.7
Standard deviation 4.8
Values 17 13 4 12 8.4
[30]
HepG2 GNS
Mean 81.3
Standard deviation 7.9
Values 87 76
[31]
HepG2.C3A GNS
Mean 56.4
Standard deviation 4.7
Values 60 53
[32]
HuH.7 GNS
Mean 91.4
Standard deviation 13
Values 1e+02 97 77
[33]
SNU475 GNS
Mean 87.8
Standard deviation 16
Values 99 77
[34]
THLE GNS
Mean 119
Standard deviation 32
Values 96 1.4e+02
[35]
liver GNS
Mean 71.6
Standard deviation 24
Values 44 1e+02 66 76
[36]
ref_hepatocyte IDS
Mean 6.6
Standard deviation 4
Values 1.7 8.7 12 5 5.4
[37]
HepG2 IDS
Mean 16.9
Standard deviation 2.4
Values 19 15
[38]
HepG2.C3A IDS
Mean 10.2
Standard deviation 0.54
Values 9.8 11
[39]
HuH.7 IDS
Mean 6.65
Standard deviation 2.1
Values 5.9 9 5
[40]
SNU475 IDS
Mean 49.1
Standard deviation 1.7
Values 50 48
[41]
THLE IDS
Mean 30.9
Standard deviation 4
Values 28 34
[42]
liver IDS
Mean 21.3
Standard deviation 4.6
Values 27 15 22 22
[43]
ref_hepatocyte HGSNAT
Mean 4.04
Standard deviation 1.6
Values 5.4 2.4 2.6 4 5.8
[44]
HepG2 HGSNAT
Mean 12.5
Standard deviation 3.7
Values 9.8 15
[45]
HepG2.C3A HGSNAT
Mean 9.74
Standard deviation 2.6
Values 12 7.9
[46]
HuH.7 HGSNAT
Mean 11.4
Standard deviation 1.7
Values 12 12 9.4
[47]
SNU475 HGSNAT
Mean 11.2
Standard deviation 4.7
Values 15 7.9
[48]
THLE HGSNAT
Mean 12.8
Standard deviation 2.9
Values 11 15
[49]
liver HGSNAT
Mean 13.4
Standard deviation 1.5
Values 12 14 15 13
[50]
ref_hepatocyte SGSH
Mean 3.8
Standard deviation 3.4
Values 9.9 1.8 2.8 1.9 2.6
[51]
HepG2 SGSH
Mean 27.9
Standard deviation 0.23
Values 28 28
[52]
HepG2.C3A SGSH
Mean 14.4
Standard deviation 5.6
Values 18 10
[53]
HuH.7 SGSH
Mean 4.87
Standard deviation 0.69
Values 5.2 4.1 5.4
[54]
SNU475 SGSH
Mean 8.08
Standard deviation 1.6
Values 9.2 6.9
[55]
THLE SGSH
Mean 9.61
Standard deviation 1.2
Values 8.8 10
[56]
liver SGSH
Mean 7.46
Standard deviation 5.8
Values 15 2.3 9 3.6
[57]
ref_hepatocyte GALNS
Mean 2.75
Standard deviation 1
Values 2.3 1.7 2 4 3.7
[58]
HepG2 GALNS
Mean 18.4
Standard deviation 5.4
Values 22 15
[59]
HepG2.C3A GALNS
Mean 8.83
Standard deviation 1.2
Values 9.7 8
[60]
HuH.7 GALNS
Mean 8.79
Standard deviation 1.8
Values 9.7 6.7 9.9
[61]
SNU475 GALNS
Mean 8.1
Standard deviation 4.4
Values 11 5
[62]
THLE GALNS
Mean 9.76
Standard deviation 0.35
Values 9.5 10
[63]
liver GALNS
Mean 6.69
Standard deviation 2.6
Values 8.1 5.2 9.6 3.9
[64]
ref_hepatocyte ARSB
Mean 1.85
Standard deviation 1.5
Values 4.3 0.43 1.1 1.1 2.3
[65]
HepG2 ARSB
Mean 50.8
Standard deviation 1.2
Values 50 52
[66]
HepG2.C3A ARSB
Mean 17.1
Standard deviation 4.2
Values 14 20
[67]
HuH.7 ARSB
Mean 10.6
Standard deviation 2.5
Values 12 7.7 12
[68]
SNU475 ARSB
Mean 9.69
Standard deviation 3.6
Values 12 7.1
[69]
THLE ARSB
Mean 15.3
Standard deviation 3.2
Values 13 18
[70]
liver ARSB
Mean 11.6
Standard deviation 6.3
Values 7.9 11 6.6 21
[71]
ref_hepatocyte IDUA
Mean 1.21
Standard deviation 1.4
Values 0 0.052 0.69 3.2 2.1
[72]
HepG2 IDUA
Mean 0.506
Standard deviation 0.019
Values 0.49 0.52
[73]
HepG2.C3A IDUA
Mean 0.666
Standard deviation 0.49
Values 1 0.32
[74]
HuH.7 IDUA
Mean 0.828
Standard deviation 0.42
Values 0.39 1.2 0.85
[75]
SNU475 IDUA
Mean 3.72
Standard deviation 1.5
Values 4.8 2.7
[76]
THLE IDUA
Mean 1.31
Standard deviation 0.3
Values 1.5 1.1
[77]
liver IDUA
Mean 1.81
Standard deviation 0.66
Values 2.7 1.1 1.9 1.6