REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 LSM3 U6 snRNA-associated Sm-like protein LSm3 [1] -1.56[2] -1.38[3] -1.59[4] -1.60[5] -1.19[6] -1.24[7]
2 LSM4 U6 snRNA-associated Sm-like protein LSm4 [8] -0.10[9] 0.14[10] 0.68[11] -0.88[12] 0.08[13] -0.83[14]
3 LSM2 U6 snRNA-associated Sm-like protein LSm2 [15] -1.02[16] -1.30[17] -1.66[18] -1.29[19] -1.82[20] -3.18[21]
4 LSM7 U6 snRNA-associated Sm-like protein LSm7 [22] -1.01[23] -0.72[24] -1.70[25] -2.42[26] -2.10[27] -2.73[28]
5 LSM1 U6 snRNA-associated Sm-like protein LSm1 [29] -1.53[30] -1.75[31] -1.61[32] -1.85[33] -1.75[34] -1.55[35]
6 LSM6 U6 snRNA-associated Sm-like protein LSm6 [36] -1.59[37] -1.98[38] -1.92[39] -2.31[40] -1.97[41] -1.87[42]
7 LSM5 U6 snRNA-associated Sm-like protein LSm5 [43] 0.24[44] 0.85[45] 0.21[46] -0.13[47] -0.05[48] -0.17[49]
8 DDX6 Probable ATP-dependent RNA helicase DDX6 [50] 2.03[51] 1.27[52] 1.12[53] 2.63[54] 1.99[55] 2.24[56]
9 EDC4 Enhancer of mRNA-decapping protein 4 [57] 2.14[58] 1.85[59] 1.62[60] 2.11[61] 1.84[62] 1.41[63]
10 PATL1 Protein PAT1 homolog 1 [64] 1.77[65] 1.24[66] 2.62[67] 2.20[68] 2.23[69] 1.55[70]
11 EDC3 Enhancer of mRNA-decapping protein 3 [71] 2.12[72] 1.46[73] 1.95[74] 2.40[75] 1.95[76] 0.92[77]
12 DCP1B mRNA-decapping enzyme 1B [78] 0.86[79] 0.32[80] 0.41[81] -0.62[82] -0.04[83] 0.05[84]
13 DCP1A mRNA-decapping enzyme 1A [85] 2.34[86] 2.34[87] 1.41[88] 1.93[89] 2.70[90] 3.24[91]
14 DCP2 m7GpppN-mRNA hydrolase [92] 2.31[93] 3.65[94] 2.45[95] 2.98[96] 2.77[97] 3.68[98]
15 XRN1 5'-3' exoribonuclease 1 [99] 1.37[100] 2.50[101] 2.53[102] 3.50[103] 3.26[104] 4.98[105]
[1]
ref_hepatocyte LSM3
Mean 37.6
Standard deviation 16
Values 24 29 26 48 61
[2]
HepG2 LSM3
Mean 19.6
Standard deviation 6.7
Values 15 24
[3]
HepG2.C3A LSM3
Mean 25.8
Standard deviation 19
Values 13 39
[4]
HuH.7 LSM3
Mean 27.3
Standard deviation 8.8
Values 30 17 34
[5]
SNU475 LSM3
Mean 15.6
Standard deviation 0.46
Values 16 15
[6]
THLE LSM3
Mean 25
Standard deviation 4.8
Values 22 28
[7]
liver LSM3
Mean 16.2
Standard deviation 16
Values 29 3.2 30 2.1
[8]
ref_hepatocyte LSM4
Mean 36
Standard deviation 22
Values 37 73 22 26 22
[9]
HepG2 LSM4
Mean 51.4
Standard deviation 7.5
Values 57 46
[10]
HepG2.C3A LSM4
Mean 70.9
Standard deviation 7.4
Values 66 76
[11]
HuH.7 LSM4
Mean 126
Standard deviation 47
Values 1.2e+02 84 1.8e+02
[12]
SNU475 LSM4
Mean 24.4
Standard deviation 2.5
Values 26 23
[13]
THLE LSM4
Mean 57.8
Standard deviation 6.1
Values 53 62
[14]
liver LSM4
Mean 20.7
Standard deviation 16
Values 34 7 35 6.3
[15]
ref_hepatocyte LSM2
Mean 28.8
Standard deviation 13
Values 45 40 25 21 13
[16]
HepG2 LSM2
Mean 21.8
Standard deviation 3
Values 24 20
[17]
HepG2.C3A LSM2
Mean 21
Standard deviation 1.3
Values 22 20
[18]
HuH.7 LSM2
Mean 19.9
Standard deviation 6
Values 20 14 26
[19]
SNU475 LSM2
Mean 14.8
Standard deviation 0.84
Values 14 15
[20]
THLE LSM2
Mean 12.4
Standard deviation 1.2
Values 11 13
[21]
liver LSM2
Mean 3.24
Standard deviation 3
Values 5.3 0.66 6.3 0.74
[22]
ref_hepatocyte LSM7
Mean 28.7
Standard deviation 12
Values 13 18 36 34 42
[23]
HepG2 LSM7
Mean 21.9
Standard deviation 2.1
Values 20 23
[24]
HepG2.C3A LSM7
Mean 31
Standard deviation 4.5
Values 28 34
[25]
HuH.7 LSM7
Mean 19.3
Standard deviation 7.8
Values 19 12 27
[26]
SNU475 LSM7
Mean 6.74
Standard deviation 0.65
Values 7.2 6.3
[27]
THLE LSM7
Mean 10.2
Standard deviation 0.34
Values 10 9.9
[28]
liver LSM7
Mean 4.4
Standard deviation 3.6
Values 7.3 1.4 7.7 1.1
[29]
ref_hepatocyte LSM1
Mean 28.5
Standard deviation 13
Values 25 50 30 17 21
[30]
HepG2 LSM1
Mean 15.2
Standard deviation 2.9
Values 13 17
[31]
HepG2.C3A LSM1
Mean 15.1
Standard deviation 5.6
Values 11 19
[32]
HuH.7 LSM1
Mean 20.4
Standard deviation 5.7
Values 19 15 27
[33]
SNU475 LSM1
Mean 9.9
Standard deviation 1
Values 11 9.2
[34]
THLE LSM1
Mean 12.9
Standard deviation 0.92
Values 14 12
[35]
liver LSM1
Mean 9.91
Standard deviation 6.9
Values 16 4.3 16 3.7
[36]
ref_hepatocyte LSM6
Mean 13.4
Standard deviation 3.9
Values 14 16 9.1 9.8 18
[37]
HepG2 LSM6
Mean 6.84
Standard deviation 1.2
Values 6 7.7
[38]
HepG2.C3A LSM6
Mean 6.08
Standard deviation 3.3
Values 3.7 8.4
[39]
HuH.7 LSM6
Mean 7.8
Standard deviation 2.1
Values 8.5 5.5 9.4
[40]
SNU475 LSM6
Mean 3.41
Standard deviation 0.82
Values 4 2.8
[41]
THLE LSM6
Mean 5.18
Standard deviation 0.58
Values 4.8 5.6
[42]
liver LSM6
Mean 3.75
Standard deviation 3.3
Values 6.8 0.88 6.4 0.9
[43]
ref_hepatocyte LSM5
Mean 11.7
Standard deviation 6.2
Values 15 18 1.7 10 14
[44]
HepG2 LSM5
Mean 21.3
Standard deviation 7.5
Values 16 27
[45]
HepG2.C3A LSM5
Mean 37.7
Standard deviation 21
Values 23 52
[46]
HuH.7 LSM5
Mean 29.7
Standard deviation 12
Values 30 17 41
[47]
SNU475 LSM5
Mean 13.4
Standard deviation 0.051
Values 13 13
[48]
THLE LSM5
Mean 17.2
Standard deviation 2.3
Values 16 19
[49]
liver LSM5
Mean 10.6
Standard deviation 9.6
Values 18 2.9 20 1.8
[50]
ref_hepatocyte DDX6
Mean 7.16
Standard deviation 2.7
Values 9 10 7.3 3.2 6.2
[51]
HepG2 DDX6
Mean 44.9
Standard deviation 12
Values 36 53
[52]
HepG2.C3A DDX6
Mean 30.8
Standard deviation 4.1
Values 28 34
[53]
HuH.7 DDX6
Mean 34.2
Standard deviation 5.6
Values 40 34 29
[54]
SNU475 DDX6
Mean 55.7
Standard deviation 15
Values 67 45
[55]
THLE DDX6
Mean 43.2
Standard deviation 8
Values 38 49
[56]
liver DDX6
Mean 34.5
Standard deviation 28
Values 12 62 9 56
[57]
ref_hepatocyte EDC4
Mean 5.66
Standard deviation 1.5
Values 6.1 5.7 7.9 4.7 4
[58]
HepG2 EDC4
Mean 38.4
Standard deviation 4
Values 36 41
[59]
HepG2.C3A EDC4
Mean 36.5
Standard deviation 1.7
Values 38 35
[60]
HuH.7 EDC4
Mean 38.2
Standard deviation 8.2
Values 44 29 41
[61]
SNU475 EDC4
Mean 30.7
Standard deviation 3.3
Values 33 28
[62]
THLE EDC4
Mean 30.8
Standard deviation 0.19
Values 31 31
[63]
liver EDC4
Mean 15.4
Standard deviation 2.2
Values 14 13 18 16
[64]
ref_hepatocyte PATL1
Mean 4.63
Standard deviation 1.6
Values 4.2 2.5 6.5 5.8 4.1
[65]
HepG2 PATL1
Mean 24.3
Standard deviation 3.7
Values 22 27
[66]
HepG2.C3A PATL1
Mean 19.5
Standard deviation 0.94
Values 20 19
[67]
HuH.7 PATL1
Mean 62.5
Standard deviation 5.8
Values 68 63 57
[68]
SNU475 PATL1
Mean 26.6
Standard deviation 2
Values 25 28
[69]
THLE PATL1
Mean 33
Standard deviation 2.6
Values 31 35
[70]
liver PATL1
Mean 13.8
Standard deviation 4.5
Values 19 8.9 15 12
[71]
ref_hepatocyte EDC3
Mean 3.49
Standard deviation 1.3
Values 4.4 4.6 4.2 2.3 1.9
[72]
HepG2 EDC3
Mean 23.3
Standard deviation 1.8
Values 22 25
[73]
HepG2.C3A EDC3
Mean 17.1
Standard deviation 0.6
Values 18 17
[74]
HuH.7 EDC3
Mean 29.5
Standard deviation 3.5
Values 32 25 31
[75]
SNU475 EDC3
Mean 23.1
Standard deviation 1.1
Values 22 24
[76]
THLE EDC3
Mean 20.4
Standard deviation 0.71
Values 20 21
[77]
liver EDC3
Mean 6.72
Standard deviation 1.6
Values 8 5.1 8.1 5.7
[78]
ref_hepatocyte DCP1B
Mean 2.67
Standard deviation 1.2
Values 2.3 0.73 3.7 3.4 3.2
[79]
HepG2 DCP1B
Mean 7.43
Standard deviation 0.93
Values 8.1 6.8
[80]
HepG2.C3A DCP1B
Mean 5.96
Standard deviation 0.72
Values 6.5 5.4
[81]
HuH.7 DCP1B
Mean 7.8
Standard deviation 0.26
Values 7.7 8.1 7.6
[82]
SNU475 DCP1B
Mean 2.17
Standard deviation 0.072
Values 2.2 2.1
[83]
THLE DCP1B
Mean 3.94
Standard deviation 0.21
Values 3.8 4.1
[84]
liver DCP1B
Mean 2.81
Standard deviation 1.9
Values 4.4 1.1 4.5 1.2
[85]
ref_hepatocyte DCP1A
Mean 1.83
Standard deviation 1.1
Values 3.5 1.5 2.5 0.84 0.81
[86]
HepG2 DCP1A
Mean 14.3
Standard deviation 0.89
Values 15 14
[87]
HepG2.C3A DCP1A
Mean 16.6
Standard deviation 4.4
Values 20 13
[88]
HuH.7 DCP1A
Mean 10.7
Standard deviation 2.4
Values 11 13 8.3
[89]
SNU475 DCP1A
Mean 8.77
Standard deviation 0.21
Values 8.9 8.6
[90]
THLE DCP1A
Mean 18.1
Standard deviation 0.25
Values 18 18
[91]
liver DCP1A
Mean 17.6
Standard deviation 11
Values 27 8.2 27 8.4
[92]
ref_hepatocyte DCP2
Mean 1.54
Standard deviation 1.2
Values 3.4 2.2 0.65 0.48 1
[93]
HepG2 DCP2
Mean 11.8
Standard deviation 4.5
Values 8.6 15
[94]
HepG2.C3A DCP2
Mean 34.5
Standard deviation 0.73
Values 34 35
[95]
HuH.7 DCP2
Mean 18.4
Standard deviation 1.8
Values 21 17 18
[96]
SNU475 DCP2
Mean 15.3
Standard deviation 1.8
Values 17 14
[97]
THLE DCP2
Mean 15.9
Standard deviation 2.3
Values 17 14
[98]
liver DCP2
Mean 20.1
Standard deviation 9
Values 10 31 15 24
[99]
ref_hepatocyte XRN1
Mean 1.16
Standard deviation 0.38
Values 1.2 0.93 0.77 1.1 1.8
[100]
HepG2 XRN1
Mean 4.6
Standard deviation 2.1
Values 3.1 6.1
[101]
HepG2.C3A XRN1
Mean 11.7
Standard deviation 1.4
Values 13 11
[102]
HuH.7 XRN1
Mean 14.7
Standard deviation 7.6
Values 13 23 7.7
[103]
SNU475 XRN1
Mean 16.4
Standard deviation 4
Values 19 14
[104]
THLE XRN1
Mean 16.8
Standard deviation 3.5
Values 19 14
[105]
liver XRN1
Mean 37.2
Standard deviation 15
Values 32 51 19 47