REACTOME_MITOPHAGY | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | UBB | Polyubiquitin-B | [1] | -0.74[2] | -0.93[3] | -0.89[4] | -1.10[5] | -0.70[6] | -0.17[7] |
2 | SQSTM1 | Sequestosome-1 | [8] | -0.29[9] | -1.34[10] | -0.90[11] | 0.51[12] | 0.36[13] | -0.09[14] |
3 | RPS27A | Ubiquitin-40S ribosomal protein S27a | [15] | [16] | [17] | [18] | [19] | [20] | [21] |
4 | UBC | Polyubiquitin-C | [22] | -0.29[23] | -0.18[24] | -0.52[25] | -0.24[26] | -0.32[27] | 0.28[28] |
5 | VDAC1 | Voltage-dependent anion-selective channel protein 1 | [29] | 1.11[30] | 0.74[31] | 0.42[32] | 0.83[33] | 1.04[34] | 0.77[35] |
6 | TOMM6 | Mitochondrial import receptor subunit TOM6 homolog | [36] | 0.38[37] | 0.85[38] | -0.09[39] | 0.15[40] | -0.44[41] | -0.84[42] |
7 | UBA52 | Ubiquitin-60S ribosomal protein L40 | [43] | 2.14[44] | 2.06[45] | 2.99[46] | 1.15[47] | 1.90[48] | 1.05[49] |
8 | TOMM5 | Mitochondrial import receptor subunit TOM5 homolog | [50] | 0.40[51] | 0.95[52] | 1.17[53] | -1.01[54] | -0.07[55] | -0.35[56] |
9 | TOMM7 | Mitochondrial import receptor subunit TOM7 homolog | [57] | -0.71[58] | 0.13[59] | 1.44[60] | -0.54[61] | -0.47[62] | -0.22[63] |
10 | CSNK2B | Casein kinase II subunit beta | [64] | 1.12[65] | 0.96[66] | 0.23[67] | 0.69[68] | 0.36[69] | 0.20[70] |
11 | TOMM22 | Mitochondrial import receptor subunit TOM22 homolog | [71] | 0.33[72] | 0.35[73] | 0.64[74] | -0.58[75] | -0.33[76] | 0.06[77] |
12 | TOMM20 | Mitochondrial import receptor subunit TOM20 homolog | [78] | 2.15[79] | 2.85[80] | 3.15[81] | 2.37[82] | 1.73[83] | 0.73[84] |
13 | CSNK2A1 | Casein kinase II subunit alpha | [85] | 1.58[86] | 1.46[87] | 1.28[88] | 1.32[89] | 0.90[90] | -0.03[91] |
14 | PINK1 | Serine/threonine-protein kinase PINK1, mitochondrial | [92] | 0.35[93] | 1.14[94] | -1.93[95] | 0.65[96] | 0.38[97] | 2.14[98] |
15 | TOMM40 | Mitochondrial import receptor subunit TOM40 homolog | [99] | 1.66[100] | 1.45[101] | 1.21[102] | 1.11[103] | 1.10[104] | 0.29[105] |
16 | MAP1LC3 | Microtubule-associated proteins 1A/1B light chain 3B | [106] | 2.18[107] | 1.92[108] | 0.57[109] | 1.83[110] | 2.38[111] | 1.15[112] |
17 | MFN2 | Mitofusin-2 | [113] | 2.16[114] | 3.05[115] | 1.85[116] | 2.56[117] | 2.45[118] | 2.79[119] |
18 | PGAM5 | Serine/threonine-protein phosphatase PGAM5, mitochondrial | [120] | 2.33[121] | 2.46[122] | 1.81[123] | 1.65[124] | 1.71[125] | 1.46[126] |
19 | CSNK2A2 | Casein kinase II subunit alpha' | [127] | 1.66[128] | 1.73[129] | 1.61[130] | 1.27[131] | 1.41[132] | -0.50[133] |
20 | MAP1LC3 | Microtubule-associated proteins 1A/1B light chain 3A | [134] | -7.57[135] | -9.02[136] | -8.50[137] | -1.56[138] | 0.33[139] | 0.76[140] |
21 | ATG5 | Autophagy protein 5 | [141] | 1.24[142] | 2.28[143] | 1.83[144] | 2.46[145] | 2.15[146] | 2.55[147] |
22 | MFN1 | Mitofusin-1 | [148] | 1.62[149] | 2.30[150] | 2.10[151] | 2.57[152] | 2.47[153] | 2.61[154] |
23 | ATG12 | Ubiquitin-like protein ATG12 | [155] | 1.90[156] | 2.80[157] | 2.62[158] | 3.14[159] | 2.86[160] | 3.14[161] |
24 | SRC | Proto-oncogene tyrosine-protein kinase Src | [162] | 4.49[163] | 4.48[164] | 3.37[165] | 4.08[166] | 3.20[167] | 0.85[168] |
25 | FUNDC1 | FUN14 domain-containing protein 1 | [169] | 1.08[170] | 1.40[171] | 1.68[172] | 1.95[173] | 2.04[174] | 0.34[175] |
26 | ULK1 | Serine/threonine-protein kinase ULK1 | [176] | 2.77[177] | 3.06[178] | 4.15[179] | 3.66[180] | 2.94[181] | 3.60[182] |
27 | PRKN | E3 ubiquitin-protein ligase parkin | [183] | [184] | [185] | [186] | [187] | [188] | [189] |
28 | TOMM70 | Mitochondrial import receptor subunit TOM70 | [190] | [191] | [192] | [193] | [194] | [195] | [196] |
29 | MTERF3 | Transcription termination factor 3, mitochondrial | [197] | [198] | [199] | [200] | [201] | [202] | [203] |