REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT |
Return to index |
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Order |
Gene |
Description |
ref_hepatocyte |
HepG2 |
HepG2.C3A |
HuH.7 |
SNU475 |
THLE |
liver |
1 |
HSPD1 |
60 kDa heat shock protein, mitochondrial |
[1] |
0.40[2] |
0.96[3] |
0.11[4] |
-0.35[5] |
-0.23[6] |
-0.12[7] |
2 |
CHCHD2 |
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 |
[8] |
-0.46[9] |
-0.58[10] |
0.08[11] |
-0.47[12] |
-0.64[13] |
-1.05[14] |
3 |
HSPA9 |
Stress-70 protein, mitochondrial |
[15] |
0.60[16] |
0.09[17] |
0.34[18] |
0.36[19] |
0.81[20] |
1.26[21] |
4 |
NDUFB8 |
NADH dehydrogenase [ubiquinone] 1
beta subcomplex subunit 8, mitochondrial |
-1.74[22] |
-1.84[23] |
-1.08[24] |
-1.90[25] |
-1.37[26] |
-0.99[27] |
5 |
VDAC1 |
Voltage-dependent anion-selective channel protein 1 |
[28] |
0.38[29] |
-0.42[30] |
-0.37[31] |
0.49[32] |
0.74[33] |
-0.09[34] |
6 |
CHCHD10 |
Coiled-coil-helix-coiled-coil-helix
domain-containing protein 10, mitochondrial |
-3.18[35] |
-3.89[36] |
-2.86[37] |
-4.06[38] |
-4.24[39] |
-0.57[40] |
7 |
SLC25A6 |
ADP/ATP translocase 3 |
[41] |
[42] |
[43] |
[44] |
[45] |
[46] |
[47] |
8 |
COX17 |
Cytochrome c oxidase copper chaperone |
[48] |
-3.08[49] |
-2.91[50] |
-3.80[51] |
-2.83[52] |
-2.50[53] |
-1.57[54] |
9 |
TOMM6 |
Mitochondrial import receptor subunit TOM6 homolog |
[55] |
-0.36[56] |
-0.31[57] |
-0.88[58] |
-0.19[59] |
-0.74[60] |
-1.69[61] |
10 |
TOMM5 |
Mitochondrial import receptor subunit TOM5 homolog |
[62] |
-0.33[63] |
-0.22[64] |
0.38[65] |
-1.35[66] |
-0.37[67] |
-1.21[68] |
11 |
CYC1 |
Cytochrome c1, heme protein, mitochondrial |
[69] |
-0.07[70] |
0.43[71] |
0.02[72] |
0.48[73] |
0.12[74] |
0.52[75] |
12 |
TOMM7 |
Mitochondrial import receptor subunit TOM7 homolog |
[76] |
-1.45[77] |
-1.03[78] |
0.65[79] |
-0.87[80] |
-0.77[81] |
-1.08[82] |
13 |
TIMM17A |
Mitochondrial import inner membrane translocase subunit Tim17-A |
[83] |
-0.83[84] |
-1.26[85] |
-1.57[86] |
0.57[87] |
0.33[88] |
-0.02[89] |
14 |
TOMM22 |
Mitochondrial import receptor subunit TOM22 homolog |
[90] |
-0.40[91] |
-0.81[92] |
-0.15[93] |
-0.92[94] |
-0.63[95] |
-0.80[96] |
15 |
TOMM20 |
Mitochondrial import receptor subunit TOM20 homolog |
[97] |
1.41[98] |
1.69[99] |
2.36[100] |
2.03[101] |
1.43[102] |
-0.13[103] |
16 |
TIMM23 |
Mitochondrial import inner membrane translocase subunit Tim23 |
[104] |
-0.21[105] |
-0.22[106] |
-1.31[107] |
0.58[108] |
0.17[109] |
-0.32[110] |
17 |
GRPEL1 |
GrpE protein homolog 1, mitochondrial |
[111] |
-0.01[112] |
-0.81[113] |
-0.81[114] |
0.04[115] |
-0.52[116] |
0.40[117] |
18 |
OTC |
Ornithine carbamoyltransferase, mitochondrial |
[118] |
-9.44[119] |
-8.95[120] |
-3.42[121] |
-11.59[122] |
-10.33[123] |
0.16[124] |
19 |
TIMM10 |
Mitochondrial import inner membrane translocase subunit Tim10 |
[125] |
-1.31[126] |
-1.85[127] |
-0.40[128] |
-1.49[129] |
-1.43[130] |
-1.56[131] |
20 |
TIMM8B |
Mitochondrial import inner membrane translocase subunit Tim8 B |
[132] |
-1.06[133] |
-1.03[134] |
-1.53[135] |
-0.73[136] |
-0.82[137] |
-0.22[138] |
21 |
LDHD |
Probable D-lactate dehydrogenase, mitochondrial |
[139] |
-3.56[140] |
-2.31[141] |
-4.30[142] |
-7.72[143] |
-8.32[144] |
1.02[145] |
22 |
TOMM40 |
Mitochondrial import receptor subunit TOM40 homolog |
[146] |
0.92[147] |
0.29[148] |
0.42[149] |
0.78[150] |
0.80[151] |
-0.56[152] |
23 |
CMC2 |
COX assembly mitochondrial protein 2 homolog |
[153] |
-1.37[154] |
-0.94[155] |
-0.03[156] |
-0.84[157] |
-0.45[158] |
-1.08[159] |
24 |
TIMM13 |
Mitochondrial import inner membrane translocase subunit Tim13 |
[160] |
-0.04[161] |
0.25[162] |
-0.22[163] |
-0.52[164] |
0.55[165] |
0.57[166] |
25 |
PMPCA |
Mitochondrial-processing peptidase subunit alpha |
[167] |
0.77[168] |
0.33[169] |
0.67[170] |
0.37[171] |
0.74[172] |
0.97[173] |
26 |
ACO2 |
Aconitate hydratase, mitochondrial |
[174] |
0.51[175] |
0.15[176] |
0.55[177] |
0.31[178] |
0.46[179] |
1.08[180] |
27 |
SLC25A13 |
Calcium-binding mitochondrial carrier protein Aralar2 |
[181] |
0.49[182] |
0.55[183] |
1.07[184] |
0.87[185] |
-0.40[186] |
2.29[187] |
28 |
SAMM50 |
Sorting and assembly machinery component 50 homolog |
[188] |
0.48[189] |
0.43[190] |
0.32[191] |
0.07[192] |
0.33[193] |
-0.08[194] |
29 |
CHCHD3 |
MICOS complex subunit MIC19 |
[195] |
0.22[196] |
-0.23[197] |
-0.05[198] |
1.19[199] |
1.05[200] |
0.13[201] |
30 |
CHCHD5 |
Coiled-coil-helix-coiled-coil-helix domain-containing protein 5 |
[202] |
-1.64[203] |
-1.22[204] |
-2.13[205] |
-1.59[206] |
-1.86[207] |
-0.80[208] |
31 |
PAM16 |
Mitochondrial import inner membrane translocase subunit TIM16 |
[209] |
-3.47[210] |
-3.70[211] |
-3.24[212] |
-4.37[213] |
-3.59[214] |
-5.66[215] |
32 |
TIMM44 |
Mitochondrial import inner membrane translocase subunit TIM44 |
[216] |
0.36[217] |
-0.02[218] |
0.28[219] |
-0.47[220] |
0.44[221] |
-0.34[222] |
33 |
CS |
Citrate synthase, mitochondrial |
[223] |
3.06[224] |
2.41[225] |
2.13[226] |
2.57[227] |
2.60[228] |
1.15[229] |
34 |
DNAJC19 |
Mitochondrial import inner membrane translocase subunit TIM14 |
[230] |
-0.84[231] |
-0.58[232] |
-0.80[233] |
-1.25[234] |
-0.27[235] |
0.57[236] |
35 |
TIMM17B |
Mitochondrial import inner membrane translocase subunit Tim17-B |
[237] |
0.30[238] |
0.28[239] |
1.46[240] |
0.64[241] |
-0.42[242] |
0.10[243] |
36 |
PMPCB |
Mitochondrial-processing peptidase subunit beta |
[244] |
0.86[245] |
1.04[246] |
1.27[247] |
1.63[248] |
1.43[249] |
1.63[250] |
37 |
IDH3G |
Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial |
[251] |
-0.48[252] |
-0.72[253] |
-0.28[254] |
1.00[255] |
0.58[256] |
0.47[257] |
38 |
PITRM1 |
Presequence protease, mitochondrial |
[258] |
0.73[259] |
0.10[260] |
-0.90[261] |
2.50[262] |
1.74[263] |
1.10[264] |
39 |
TIMM21 |
Mitochondrial import inner membrane translocase subunit Tim21 |
[265] |
-0.59[266] |
-1.12[267] |
-1.16[268] |
-0.06[269] |
0.49[270] |
0.25[271] |
40 |
TIMM50 |
Mitochondrial import inner membrane translocase subunit TIM50 |
[272] |
1.12[273] |
0.44[274] |
1.14[275] |
1.25[276] |
1.41[277] |
0.35[278] |
41 |
MTX1 |
Metaxin-1 |
[279] |
0.67[280] |
0.23[281] |
1.27[282] |
1.54[283] |
1.18[284] |
0.21[285] |
42 |
TIMM8A |
Mitochondrial import inner membrane translocase subunit Tim8 A |
[286] |
-0.43[287] |
-0.83[288] |
-0.47[289] |
-0.41[290] |
-0.56[291] |
-0.51[292] |
43 |
SLC25A4 |
ADP/ATP translocase 1 |
[293] |
0.71[294] |
0.25[295] |
-1.94[296] |
0.42[297] |
0.71[298] |
2.02[299] |
44 |
MTX2 |
Metaxin-2 |
[300] |
0.97[301] |
0.84[302] |
1.36[303] |
1.67[304] |
0.95[305] |
0.10[306] |
45 |
TIMM22 |
Mitochondrial import inner membrane translocase subunit Tim22 |
[307] |
0.33[308] |
-0.69[309] |
-0.06[310] |
0.31[311] |
0.46[312] |
-0.46[313] |
46 |
CHCHD4 |
Mitochondrial intermembrane space
import and assembly protein 40 |
-0.39[314] |
-0.69[315] |
0.01[316] |
-0.66[317] |
0.19[318] |
-0.51[319] |
47 |
HSCB |
Iron-sulfur cluster co-chaperone protein HscB, mitochondrial |
[320] |
-1.34[321] |
-0.63[322] |
-0.12[323] |
-0.81[324] |
-1.38[325] |
-0.29[326] |
48 |
TIMM9 |
Mitochondrial import inner membrane translocase subunit Tim9 |
[327] |
0.07[328] |
0.28[329] |
1.03[330] |
0.28[331] |
0.59[332] |
-0.39[333] |
49 |
BCS1L |
Mitochondrial chaperone BCS1 |
[334] |
0.34[335] |
0.22[336] |
0.13[337] |
0.38[338] |
0.74[339] |
0.29[340] |
50 |
CHCHD7 |
Coiled-coil-helix-coiled-coil-helix domain-containing protein 7 |
[341] |
0.48[342] |
0.75[343] |
0.48[344] |
0.70[345] |
1.27[346] |
0.67[347] |
51 |
GFER |
FAD-linked sulfhydryl oxidase ALR |
[348] |
1.43[349] |
1.50[350] |
1.06[351] |
0.32[352] |
0.68[353] |
0.05[354] |
52 |
FXN |
Frataxin, mitochondrial |
[355] |
1.13[356] |
0.94[357] |
0.02[358] |
0.12[359] |
0.59[360] |
1.87[361] |
53 |
COQ2 |
4-hydroxybenzoate polyprenyltransferase, mitochondrial |
[362] |
-0.05[363] |
-0.42[364] |
-0.57[365] |
-0.46[366] |
1.05[367] |
0.56[368] |
54 |
COX19 |
Cytochrome c oxidase assembly protein COX19 |
[369] |
1.10[370] |
1.78[371] |
2.36[372] |
1.35[373] |
1.70[374] |
1.14[375] |
55 |
GRPEL2 |
GrpE protein homolog 2, mitochondrial |
[376] |
1.13[377] |
1.29[378] |
2.00[379] |
1.78[380] |
2.72[381] |
1.58[382] |
56 |
SLC25A12 |
Calcium-binding mitochondrial carrier protein Aralar1 |
[383] |
2.91[384] |
2.67[385] |
0.27[386] |
4.52[387] |
4.74[388] |
1.11[389] |
57 |
ATP5F1B |
|
[390] |
[391] |
[392] |
[393] |
[394] |
[395] |
[396] |
58 |
COA4 |
Cytochrome c oxidase assembly factor 4 homolog, mitochondrial |
[397] |
[398] |
[399] |
[400] |
[401] |
[402] |
[403] |
59 |
CMC4 |
Cx9C motif-containing protein 4 |
[404] |
[405] |
[406] |
[407] |
[408] |
[409] |
[410] |
60 |
TIMM10B |
Mitochondrial import inner membrane translocase subunit Tim10 B |
[411] |
[412] |
[413] |
[414] |
[415] |
[416] |
[417] |
61 |
TOMM70 |
Mitochondrial import receptor subunit TOM70 |
[418] |
[419] |
[420] |
[421] |
[422] |
[423] |
[424] |
62 |
ATP5MC1 |
|
[425] |
[426] |
[427] |
[428] |
[429] |
[430] |
[431] |
63 |
TAFAZZIN |
[432] |
[433] |
[434] |
[435] |
[436] |
[437] |
[438] |
64 |
COA6 |
Cytochrome c oxidase assembly factor 6 homolog |
[439] |
[440] |
[441] |
[442] |
[443] |
[444] |
[445] |
65 |
ATP5F1A |
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[446] |
[447] |
[448] |
[449] |
[450] |
[451] |
[452] |
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