REACTOME_MITOCHONDRIAL_CALCIUM_ION_TRANSPORT Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 VDAC1 Voltage-dependent anion-selective channel protein 1 [1] -0.15[2] -0.66[3] -0.78[4] -0.12[5] 0.17[6] -0.24[7]
2 PHB2 Prohibitin-2 [8] -0.50[9] -0.07[10] 0.38[11] -1.82[12] -0.67[13] -0.85[14]
3 VDAC2 Voltage-dependent anion-selective channel protein 2 [15] -0.22[16] -0.26[17] -1.13[18] 0.00[19] -0.10[20] -1.32[21]
4 PHB Prohibitin [22] 0.28[23] 0.03[24] -0.43[25] -0.52[26] -0.49[27] -0.31[28]
5 STOML2 Stomatin-like protein 2, mitochondrial [29] -0.14[30] -0.23[31] -0.54[32] -1.05[33] -0.46[34] -0.56[35]
6 VDAC3 Voltage-dependent anion-selective channel protein 3 [36] -0.44[37] -0.69[38] -0.56[39] -0.64[40] -0.79[41] -0.54[42]
7 PARL Presenilins-associated rhomboid-like protein, mitochondrial [43] -1.58[44] -1.71[45] -1.73[46] -1.62[47] -1.14[48] -1.47[49]
8 YME1L1 ATP-dependent zinc metalloprotease YME1L1 [50] 0.44[51] 0.96[52] 1.73[53] 2.49[54] 1.62[55] 1.20[56]
9 PMPCA Mitochondrial-processing peptidase subunit alpha [57] 0.24[58] 0.09[59] 0.26[60] -0.24[61] 0.16[62] 0.82[63]
10 AFG3L2 AFG3-like protein 2 [64] 0.23[65] 0.52[66] 1.02[67] 0.78[68] 0.45[69] 0.78[70]
11 MICU1 Calcium uptake protein 1, mitochondrial [71] -0.13[72] 0.46[73] -0.21[74] 0.62[75] 0.40[76] 0.47[77]
12 AKAP1 A-kinase anchor protein 1, mitochondrial [78] 1.57[79] 1.59[80] 1.37[81] -1.27[82] -0.42[83] 1.67[84]
13 PMPCB Mitochondrial-processing peptidase subunit beta [85] 0.33[86] 0.80[87] 0.86[88] 1.02[89] 0.85[90] 1.48[91]
14 SPG7 Paraplegin [92] 0.72[93] 0.90[94] 0.18[95] 0.52[96] 0.70[97] 1.10[98]
15 LETM1 Mitochondrial proton/calcium exchanger protein [99] 1.18[100] 0.51[101] 1.25[102] 1.39[103] 1.53[104] 2.27[105]
16 MCU Calcium uniporter protein, mitochondrial [106] 1.10[107] 1.17[108] 0.93[109] 2.02[110] 1.57[111] 0.76[112]
17 SLC8A3 Sodium/calcium exchanger 3 [113] -0.35[114] -2.43[115] -3.18[116] [117] -1.76[118] 1.32[119]
18 MCUB Calcium uniporter regulatory subunit MCUb, mitochondrial [120] [121] [122] [123] [124] [125] [126]
19 MAIP1 m-AAA protease-interacting protein 1, mitochondrial [127] [128] [129] [130] [131] [132] [133]
20 MICU3 Calcium uptake protein 3, mitochondrial [134] [135] [136] [137] [138] [139] [140]
21 SLC8B1 Mitochondrial sodium/calcium exchanger protein [141] [142] [143] [144] [145] [146] [147]
22 SMDT1 Essential MCU regulator, mitochondrial [148] [149] [150] [151] [152] [153] [154]
23 MICU2 Calcium uptake protein 2, mitochondrial [155] [156] [157] [158] [159] [160] [161]
[1]
ref_hepatocyte VDAC1
Mean 106
Standard deviation 53
Values 1.9e+02 1.2e+02 66 80 70
[2]
HepG2 VDAC1
Mean 184
Standard deviation 1.3
Values 1.8e+02 1.8e+02
[3]
HepG2.C3A VDAC1
Mean 126
Standard deviation 2.5
Values 1.2e+02 1.3e+02
[4]
HuH.7 VDAC1
Mean 104
Standard deviation 14
Values 1.1e+02 89 1.2e+02
[5]
SNU475 VDAC1
Mean 108
Standard deviation 1.4
Values 1.1e+02 1.1e+02
[6]
THLE VDAC1
Mean 146
Standard deviation 33
Values 1.2e+02 1.7e+02
[7]
liver VDAC1
Mean 79
Standard deviation 36
Values 94 62 1.2e+02 40
[8]
ref_hepatocyte PHB2
Mean 98.9
Standard deviation 33
Values 73 71 1.5e+02 1.1e+02 90
[9]
HepG2 PHB2
Mean 135
Standard deviation 28
Values 1.5e+02 1.2e+02
[10]
HepG2.C3A PHB2
Mean 177
Standard deviation 19
Values 1.9e+02 1.6e+02
[11]
HuH.7 PHB2
Mean 216
Standard deviation 35
Values 2e+02 2e+02 2.6e+02
[12]
SNU475 PHB2
Mean 31
Standard deviation 2.9
Values 33 29
[13]
THLE PHB2
Mean 76.4
Standard deviation 13
Values 67 86
[14]
liver PHB2
Mean 48
Standard deviation 22
Values 67 31 67 28
[15]
ref_hepatocyte VDAC2
Mean 79.5
Standard deviation 54
Values 60 1.3e+02 1.4e+02 36 28
[16]
HepG2 VDAC2
Mean 131
Standard deviation 16
Values 1.4e+02 1.2e+02
[17]
HepG2.C3A VDAC2
Mean 124
Standard deviation 7.6
Values 1.3e+02 1.2e+02
[18]
HuH.7 VDAC2
Mean 61.1
Standard deviation 0.75
Values 61 60 62
[19]
SNU475 VDAC2
Mean 88
Standard deviation 1.1
Values 87 89
[20]
THLE VDAC2
Mean 90.9
Standard deviation 12
Values 82 99
[21]
liver VDAC2
Mean 28
Standard deviation 17
Values 41 14 45 12
[22]
ref_hepatocyte PHB
Mean 76
Standard deviation 15
Values 69 1e+02 70 78 62
[23]
HepG2 PHB
Mean 178
Standard deviation 2.8
Values 1.8e+02 1.8e+02
[24]
HepG2.C3A PHB
Mean 146
Standard deviation 41
Values 1.2e+02 1.8e+02
[25]
HuH.7 PHB
Mean 94.8
Standard deviation 36
Values 1e+02 55 1.2e+02
[26]
SNU475 PHB
Mean 58.5
Standard deviation 7.6
Values 53 64
[27]
THLE PHB
Mean 66.4
Standard deviation 7.6
Values 61 72
[28]
liver PHB
Mean 53.9
Standard deviation 28
Values 72 36 84 25
[29]
ref_hepatocyte STOML2
Mean 57
Standard deviation 11
Values 45 54 71 66 49
[30]
HepG2 STOML2
Mean 99.9
Standard deviation 7.2
Values 1e+02 95
[31]
HepG2.C3A STOML2
Mean 91.1
Standard deviation 16
Values 80 1e+02
[32]
HuH.7 STOML2
Mean 66
Standard deviation 13
Values 66 53 79
[33]
SNU475 STOML2
Mean 30.3
Standard deviation 2.3
Values 29 32
[34]
THLE STOML2
Mean 50.9
Standard deviation 7.2
Values 46 56
[35]
liver STOML2
Mean 34
Standard deviation 16
Values 44 24 50 17
[36]
ref_hepatocyte VDAC3
Mean 46.7
Standard deviation 26
Values 66 82 22 32 31
[37]
HepG2 VDAC3
Mean 66.2
Standard deviation 33
Values 43 89
[38]
HepG2.C3A VDAC3
Mean 54.5
Standard deviation 28
Values 35 74
[39]
HuH.7 VDAC3
Mean 53.5
Standard deviation 15
Values 58 36 66
[40]
SNU475 VDAC3
Mean 33.2
Standard deviation 4.6
Values 36 30
[41]
THLE VDAC3
Mean 33.3
Standard deviation 0.58
Values 34 33
[42]
liver VDAC3
Mean 28.2
Standard deviation 17
Values 40 17 46 10
[43]
ref_hepatocyte PARL
Mean 33.4
Standard deviation 19
Values 53 55 19 19 21
[44]
HepG2 PARL
Mean 21.5
Standard deviation 0.055
Values 21 22
[45]
HepG2.C3A PARL
Mean 19.1
Standard deviation 0.59
Values 19 20
[46]
HuH.7 PARL
Mean 16.9
Standard deviation 3.7
Values 17 13 20
[47]
SNU475 PARL
Mean 12
Standard deviation 0.34
Values 12 12
[48]
THLE PARL
Mean 18.6
Standard deviation 2.4
Values 17 20
[49]
liver PARL
Mean 10.6
Standard deviation 7.6
Values 18 3.8 16 4.3
[50]
ref_hepatocyte YME1L1
Mean 24.7
Standard deviation 9.2
Values 23 40 26 16 18
[51]
HepG2 YME1L1
Mean 64.6
Standard deviation 19
Values 51 78
[52]
HepG2.C3A YME1L1
Mean 90.3
Standard deviation 8.5
Values 84 96
[53]
HuH.7 YME1L1
Mean 138
Standard deviation 12
Values 1.5e+02 1.3e+02 1.3e+02
[54]
SNU475 YME1L1
Mean 153
Standard deviation 3.2
Values 1.6e+02 1.5e+02
[55]
THLE YME1L1
Mean 93.4
Standard deviation 5.9
Values 89 98
[56]
liver YME1L1
Mean 49.7
Standard deviation 13
Values 47 50 67 36
[57]
ref_hepatocyte PMPCA
Mean 21.5
Standard deviation 5.6
Values 15 16 23 27 27
[58]
HepG2 PMPCA
Mean 48.9
Standard deviation 0.76
Values 48 49
[59]
HepG2.C3A PMPCA
Mean 43
Standard deviation 0.12
Values 43 43
[60]
HuH.7 PMPCA
Mean 43.5
Standard deviation 19
Values 49 23 59
[61]
SNU475 PMPCA
Mean 20
Standard deviation 3.2
Values 22 18
[62]
THLE PMPCA
Mean 29.5
Standard deviation 8.9
Values 23 36
[63]
liver PMPCA
Mean 33.3
Standard deviation 24
Values 39 19 65 11
[64]
ref_hepatocyte AFG3L2
Mean 20.4
Standard deviation 9.9
Values 26 35 11 16 14
[65]
HepG2 AFG3L2
Mean 45.9
Standard deviation 0.38
Values 46 46
[66]
HepG2.C3A AFG3L2
Mean 54.8
Standard deviation 3.6
Values 57 52
[67]
HuH.7 AFG3L2
Mean 69.6
Standard deviation 9.9
Values 75 58 75
[68]
SNU475 AFG3L2
Mean 38.6
Standard deviation 5.6
Values 43 35
[69]
THLE AFG3L2
Mean 34.1
Standard deviation 5.8
Values 30 38
[70]
liver AFG3L2
Mean 30.6
Standard deviation 4.1
Values 35 29 33 26
[71]
ref_hepatocyte MICU1
Mean 16.9
Standard deviation 9.2
Values 21 7.8 6.4 22 27
[72]
HepG2 MICU1
Mean 29.9
Standard deviation 4.3
Values 27 33
[73]
HepG2.C3A MICU1
Mean 43.6
Standard deviation 1.4
Values 45 43
[74]
HuH.7 MICU1
Mean 24.7
Standard deviation 3.1
Values 25 21 28
[75]
SNU475 MICU1
Mean 28.6
Standard deviation 6.9
Values 33 24
[76]
THLE MICU1
Mean 27.5
Standard deviation 2.6
Values 26 29
[77]
liver MICU1
Mean 20.5
Standard deviation 9.3
Values 33 13 22 14
[78]
ref_hepatocyte AKAP1
Mean 16.8
Standard deviation 5.8
Values 27 16 12 14 16
[79]
HepG2 AKAP1
Mean 96.2
Standard deviation 12
Values 88 1e+02
[80]
HepG2.C3A AKAP1
Mean 94.9
Standard deviation 5.6
Values 91 99
[81]
HuH.7 AKAP1
Mean 73.2
Standard deviation 3.8
Values 77 70 72
[82]
SNU475 AKAP1
Mean 7.65
Standard deviation 0.84
Values 7.1 8.2
[83]
THLE AKAP1
Mean 15.4
Standard deviation 1.3
Values 14 16
[84]
liver AKAP1
Mean 46.7
Standard deviation 14
Values 67 36 44 39
[85]
ref_hepatocyte PMPCB
Mean 13.8
Standard deviation 2.8
Values 13 15 9.5 14 17
[86]
HepG2 PMPCB
Mean 33.3
Standard deviation 1.6
Values 34 32
[87]
HepG2.C3A PMPCB
Mean 45.1
Standard deviation 4.5
Values 48 42
[88]
HuH.7 PMPCB
Mean 42.1
Standard deviation 4.2
Values 38 42 46
[89]
SNU475 PMPCB
Mean 30.9
Standard deviation 1.4
Values 32 30
[90]
THLE PMPCB
Mean 30.5
Standard deviation 0.76
Values 30 31
[91]
liver PMPCB
Mean 33.8
Standard deviation 15
Values 46 25 47 17
[92]
ref_hepatocyte SPG7
Mean 13.3
Standard deviation 4.5
Values 18 14 6.1 13 15
[93]
HepG2 SPG7
Mean 42.1
Standard deviation 2.7
Values 40 44
[94]
HepG2.C3A SPG7
Mean 46.7
Standard deviation 3.2
Values 49 44
[95]
HuH.7 SPG7
Mean 25.5
Standard deviation 8.4
Values 27 16 33
[96]
SNU475 SPG7
Mean 21.1
Standard deviation 7
Values 26 16
[97]
THLE SPG7
Mean 26.6
Standard deviation 0.51
Values 27 26
[98]
liver SPG7
Mean 25.1
Standard deviation 2.2
Values 25 23 28 25
[99]
ref_hepatocyte LETM1
Mean 7.21
Standard deviation 5.3
Values 6.3 16 6.2 4.2 3
[100]
HepG2 LETM1
Mean 31.5
Standard deviation 1.1
Values 32 31
[101]
HepG2.C3A LETM1
Mean 19.2
Standard deviation 1.5
Values 18 20
[102]
HuH.7 LETM1
Mean 28.9
Standard deviation 11
Values 38 16 32
[103]
SNU475 LETM1
Mean 20.9
Standard deviation 1.6
Values 22 20
[104]
THLE LETM1
Mean 25.6
Standard deviation 7.2
Values 21 31
[105]
liver LETM1
Mean 30.5
Standard deviation 2.9
Values 27 30 31 34
[106]
ref_hepatocyte MCU
Mean 4.75
Standard deviation 2.6
Values 5.3 8.6 4.8 3.1 2
[107]
HepG2 MCU
Mean 19.6
Standard deviation 1.9
Values 18 21
[108]
HepG2.C3A MCU
Mean 20.1
Standard deviation 3.8
Values 17 23
[109]
HuH.7 MCU
Mean 15.2
Standard deviation 0.77
Values 16 14 15
[110]
SNU475 MCU
Mean 21.2
Standard deviation 5.5
Values 25 17
[111]
THLE MCU
Mean 17.3
Standard deviation 1.7
Values 16 19
[112]
liver MCU
Mean 7.05
Standard deviation 3.3
Values 7.2 5.9 11 3.6
[113]
ref_hepatocyte SLC8A3
Mean 0.0293
Standard deviation 0.066
Values 0 0 0.15 0 0
[114]
HepG2 SLC8A3
Mean 0.0444
Standard deviation 0.026
Values 0.063 0.026
[115]
HepG2.C3A SLC8A3
Mean 0.0102
Standard deviation 0.00071
Values 0.0097 0.011
[116]
HuH.7 SLC8A3
Mean 0.00547
Standard deviation 0.0095
Values 0.016 0 0
[117]
SNU475 SLC8A3
Mean 0
Standard deviation 0
Values 0 0
[118]
THLE SLC8A3
Mean 0.0106
Standard deviation 0.015
Values 0 0.021
[119]
liver SLC8A3
Mean 0.0645
Standard deviation 0.062
Values 0.024 0.13 0 0.11
[120]
ref_hepatocyte MCUB
Missing
[121]
HepG2 MCUB
Missing
[122]
HepG2.C3A MCUB
Missing
[123]
HuH.7 MCUB
Missing
[124]
SNU475 MCUB
Missing
[125]
THLE MCUB
Missing
[126]
liver MCUB
Missing
[127]
ref_hepatocyte MAIP1
Missing
[128]
HepG2 MAIP1
Missing
[129]
HepG2.C3A MAIP1
Missing
[130]
HuH.7 MAIP1
Missing
[131]
SNU475 MAIP1
Missing
[132]
THLE MAIP1
Missing
[133]
liver MAIP1
Missing
[134]
ref_hepatocyte MICU3
Missing
[135]
HepG2 MICU3
Missing
[136]
HepG2.C3A MICU3
Missing
[137]
HuH.7 MICU3
Missing
[138]
SNU475 MICU3
Missing
[139]
THLE MICU3
Missing
[140]
liver MICU3
Missing
[141]
ref_hepatocyte SLC8B1
Missing
[142]
HepG2 SLC8B1
Missing
[143]
HepG2.C3A SLC8B1
Missing
[144]
HuH.7 SLC8B1
Missing
[145]
SNU475 SLC8B1
Missing
[146]
THLE SLC8B1
Missing
[147]
liver SLC8B1
Missing
[148]
ref_hepatocyte SMDT1
Missing
[149]
HepG2 SMDT1
Missing
[150]
HepG2.C3A SMDT1
Missing
[151]
HuH.7 SMDT1
Missing
[152]
SNU475 SMDT1
Missing
[153]
THLE SMDT1
Missing
[154]
liver SMDT1
Missing
[155]
ref_hepatocyte MICU2
Missing
[156]
HepG2 MICU2
Missing
[157]
HepG2.C3A MICU2
Missing
[158]
HuH.7 MICU2
Missing
[159]
SNU475 MICU2
Missing
[160]
THLE MICU2
Missing
[161]
liver MICU2
Missing