REACTOME_MISMATCH_REPAIR Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 PCNA Proliferating cell nuclear antigen [1] 0.76[2] 0.59[3] -1.01[4] -0.80[5] -0.20[6] -2.52[7]
2 POLD2 DNA polymerase delta subunit 2 [8] -0.73[9] -0.71[10] -0.38[11] -1.45[12] -0.76[13] 0.43[14]
3 POLD4 DNA polymerase delta subunit 4 [15] -2.26[16] -2.76[17] -0.86[18] 0.86[19] -2.41[20] 0.08[21]
4 RPA2 Replication protein A 32 kDa subunit [22] -1.58[23] -1.67[24] -1.29[25] -1.33[26] -0.93[27] -1.84[28]
5 MSH6 DNA mismatch repair protein Msh6 [29] 0.19[30] 0.52[31] 0.54[32] 0.31[33] 1.05[34] 0.85[35]
6 RPA1 Replication protein A 70 kDa DNA-binding subunit [36] 1.19[37] 0.77[38] 0.86[39] 1.26[40] 1.60[41] 0.56[42]
7 RPA3 Replication protein A 14 kDa subunit [43] -0.49[44] 0.15[45] 0.69[46] -1.49[47] -0.88[48] -0.13[49]
8 MLH1 DNA mismatch repair protein Mlh1 [50] 0.72[51] 0.69[52] 1.25[53] -0.45[54] 0.53[55] 0.98[56]
9 PMS2 Mismatch repair endonuclease PMS2 [57] -1.54[58] -1.96[59] -1.24[60] -1.18[61] -1.17[62] -0.86[63]
10 MSH2 DNA mismatch repair protein Msh2 [64] 0.70[65] 1.83[66] 1.09[67] 1.55[68] 1.23[69] -0.13[70]
11 LIG1 DNA ligase 1 [71] 1.50[72] 1.37[73] 1.82[74] -0.08[75] 0.99[76] 0.19[77]
12 POLD1 DNA polymerase delta catalytic subunit [78] 1.73[79] 1.80[80] 2.43[81] 1.24[82] 2.32[83] 1.23[84]
13 MSH3 DNA mismatch repair protein Msh3 [85] 0.62[86] 1.08[87] 0.68[88] 0.89[89] 1.10[90] 2.98[91]
14 POLD3 DNA polymerase delta subunit 3 [92] 1.05[93] 0.76[94] 1.55[95] 1.53[96] 2.34[97] 1.54[98]
15 EXO1 Exonuclease 1 [99] 1.78[100] 1.91[101] 2.89[102] 3.19[103] 2.79[104] -0.91[105]
[1]
ref_hepatocyte PCNA
Mean 36
Standard deviation 33
Values 92 37 14 19 17
[2]
HepG2 PCNA
Mean 147
Standard deviation 54
Values 1.1e+02 1.9e+02
[3]
HepG2.C3A PCNA
Mean 130
Standard deviation 86
Values 69 1.9e+02
[4]
HuH.7 PCNA
Mean 46.8
Standard deviation 33
Values 53 10 76
[5]
SNU475 PCNA
Mean 56.8
Standard deviation 7.7
Values 51 62
[6]
THLE PCNA
Mean 77.4
Standard deviation 13
Values 68 86
[7]
liver PCNA
Mean 6.07
Standard deviation 2.5
Values 7.3 5.2 8.8 3
[8]
ref_hepatocyte POLD2
Mean 32.3
Standard deviation 18
Values 10 23 30 58 40
[9]
HepG2 POLD2
Mean 47
Standard deviation 5.6
Values 51 43
[10]
HepG2.C3A POLD2
Mean 47.2
Standard deviation 5.4
Values 43 51
[11]
HuH.7 POLD2
Mean 64.5
Standard deviation 25
Values 79 36 79
[12]
SNU475 POLD2
Mean 32.5
Standard deviation 4.3
Values 29 35
[13]
THLE POLD2
Mean 47.1
Standard deviation 7.9
Values 41 53
[14]
liver POLD2
Mean 42.1
Standard deviation 24
Values 67 21 57 23
[15]
ref_hepatocyte POLD4
Mean 31.5
Standard deviation 27
Values 1.6 16 19 64 57
[16]
HepG2 POLD4
Mean 15.9
Standard deviation 3.9
Values 19 13
[17]
HepG2.C3A POLD4
Mean 11.1
Standard deviation 4
Values 14 8.3
[18]
HuH.7 POLD4
Mean 45.1
Standard deviation 6.1
Values 39 51 46
[19]
SNU475 POLD4
Mean 157
Standard deviation 53
Values 1.9e+02 1.2e+02
[20]
THLE POLD4
Mean 14.6
Standard deviation 1.8
Values 13 16
[21]
liver POLD4
Mean 32.1
Standard deviation 32
Values 48 6 69 5.3
[22]
ref_hepatocyte RPA2
Mean 23.6
Standard deviation 12
Values 23 41 28 15 11
[23]
HepG2 RPA2
Mean 19
Standard deviation 3.9
Values 16 22
[24]
HepG2.C3A RPA2
Mean 17.8
Standard deviation 8.2
Values 12 24
[25]
HuH.7 RPA2
Mean 25.2
Standard deviation 11
Values 27 14 35
[26]
SNU475 RPA2
Mean 25.9
Standard deviation 7.9
Values 20 31
[27]
THLE RPA2
Mean 30.6
Standard deviation 2.7
Values 29 33
[28]
liver RPA2
Mean 6.36
Standard deviation 3.6
Values 6.9 4.2 11 3.2
[29]
ref_hepatocyte MSH6
Mean 10.9
Standard deviation 9.5
Values 23 19 4.3 4.4 3.6
[30]
HepG2 MSH6
Mean 30
Standard deviation 7.4
Values 25 35
[31]
HepG2.C3A MSH6
Mean 37.5
Standard deviation 7.9
Values 32 43
[32]
HuH.7 MSH6
Mean 41.5
Standard deviation 12
Values 50 28 47
[33]
SNU475 MSH6
Mean 37.5
Standard deviation 5.6
Values 34 41
[34]
THLE MSH6
Mean 56
Standard deviation 3.5
Values 54 59
[35]
liver MSH6
Mean 19
Standard deviation 6.7
Values 11 28 17 20
[36]
ref_hepatocyte RPA1
Mean 8.25
Standard deviation 3.9
Values 9.2 15 5.5 5.3 6.7
[37]
HepG2 RPA1
Mean 45.3
Standard deviation 8.3
Values 39 51
[38]
HepG2.C3A RPA1
Mean 33.6
Standard deviation 11
Values 26 41
[39]
HuH.7 RPA1
Mean 39
Standard deviation 14
Values 47 23 48
[40]
SNU475 RPA1
Mean 54.6
Standard deviation 1
Values 55 54
[41]
THLE RPA1
Mean 62.1
Standard deviation 11
Values 54 70
[42]
liver RPA1
Mean 11.7
Standard deviation 1.8
Values 12 12 14 9.5
[43]
ref_hepatocyte RPA3
Mean 8.22
Standard deviation 4.8
Values 6.2 7.6 1.9 11 15
[44]
HepG2 RPA3
Mean 14.1
Standard deviation 4
Values 11 17
[45]
HepG2.C3A RPA3
Mean 21.8
Standard deviation 13
Values 13 31
[46]
HuH.7 RPA3
Mean 34.5
Standard deviation 16
Values 35 18 50
[47]
SNU475 RPA3
Mean 8.05
Standard deviation 1.5
Values 9.1 7
[48]
THLE RPA3
Mean 11
Standard deviation 2.9
Values 8.9 13
[49]
liver RPA3
Mean 7.22
Standard deviation 6.1
Values 13 2.4 12 1.4
[50]
ref_hepatocyte MLH1
Mean 6.5
Standard deviation 1.5
Values 4.7 6.4 5.5 8.4 7.5
[51]
HepG2 MLH1
Mean 25.9
Standard deviation 4.9
Values 22 29
[52]
HepG2.C3A MLH1
Mean 25.1
Standard deviation 3.7
Values 22 28
[53]
HuH.7 MLH1
Mean 40.4
Standard deviation 11
Values 44 28 50
[54]
SNU475 MLH1
Mean 13.2
Standard deviation 0.12
Values 13 13
[55]
THLE MLH1
Mean 23.2
Standard deviation 4.4
Values 20 26
[56]
liver MLH1
Mean 12.4
Standard deviation 3.5
Values 11 13 17 9.1
[57]
ref_hepatocyte PMS2
Mean 5.16
Standard deviation 1.2
Values 3.8 6.9 4.6 4.7 5.7
[58]
HepG2 PMS2
Mean 4.28
Standard deviation 0.47
Values 3.9 4.6
[59]
HepG2.C3A PMS2
Mean 3.16
Standard deviation 0.96
Values 2.5 3.8
[60]
HuH.7 PMS2
Mean 5.68
Standard deviation 1.5
Values 7.4 4.7 4.9
[61]
SNU475 PMS2
Mean 6.27
Standard deviation 0.36
Values 6.5 6
[62]
THLE PMS2
Mean 5.67
Standard deviation 0.91
Values 5 6.3
[63]
liver PMS2
Mean 2.75
Standard deviation 0.94
Values 1.8 4.1 2.6 2.5
[64]
ref_hepatocyte MSH2
Mean 3.98
Standard deviation 3.2
Values 8.5 6.1 2.4 1.3 1.5
[65]
HepG2 MSH2
Mean 15.5
Standard deviation 8
Values 9.9 21
[66]
HepG2.C3A MSH2
Mean 33.8
Standard deviation 15
Values 23 45
[67]
HuH.7 MSH2
Mean 22.1
Standard deviation 10
Values 28 10 28
[68]
SNU475 MSH2
Mean 32
Standard deviation 6.8
Values 27 37
[69]
THLE MSH2
Mean 23.1
Standard deviation 1.9
Values 22 24
[70]
liver MSH2
Mean 3.5
Standard deviation 1.1
Values 2.3 4.8 4 2.9
[71]
ref_hepatocyte LIG1
Mean 3.08
Standard deviation 2.7
Values 7.4 3.8 0.82 2.1 1.3
[72]
HepG2 LIG1
Mean 21.1
Standard deviation 4.6
Values 18 24
[73]
HepG2.C3A LIG1
Mean 19
Standard deviation 5
Values 15 23
[74]
HuH.7 LIG1
Mean 28.4
Standard deviation 13
Values 35 13 37
[75]
SNU475 LIG1
Mean 8.05
Standard deviation 0.33
Values 8.3 7.8
[76]
THLE LIG1
Mean 15.1
Standard deviation 4
Values 12 18
[77]
liver LIG1
Mean 3.39
Standard deviation 0.66
Values 3.3 3.3 4.3 2.7
[78]
ref_hepatocyte POLD1
Mean 2.41
Standard deviation 0.8
Values 2 3.5 2.7 2.4 1.4
[79]
HepG2 POLD1
Mean 19.3
Standard deviation 1.9
Values 21 18
[80]
HepG2.C3A POLD1
Mean 20.1
Standard deviation 2.3
Values 18 22
[81]
HuH.7 POLD1
Mean 34
Standard deviation 15
Values 42 16 44
[82]
SNU475 POLD1
Mean 15.6
Standard deviation 2.9
Values 14 18
[83]
THLE POLD1
Mean 29.7
Standard deviation 2.6
Values 28 32
[84]
liver POLD1
Mean 5.43
Standard deviation 0.68
Values 6.2 4.7 5.8 5.1
[85]
ref_hepatocyte MSH3
Mean 1.7
Standard deviation 0.72
Values 2.9 1.5 1 1.7 1.3
[86]
HepG2 MSH3
Mean 6.3
Standard deviation 2.4
Values 4.6 8
[87]
HepG2.C3A MSH3
Mean 8.59
Standard deviation 2.2
Values 7 10
[88]
HuH.7 MSH3
Mean 7.11
Standard deviation 0.77
Values 7.9 7.1 6.3
[89]
SNU475 MSH3
Mean 8.69
Standard deviation 0.99
Values 8 9.4
[90]
THLE MSH3
Mean 9.02
Standard deviation 0.64
Values 8.6 9.5
[91]
liver MSH3
Mean 12.9
Standard deviation 2.9
Values 14 13 9 16
[92]
ref_hepatocyte POLD3
Mean 1.46
Standard deviation 0.56
Values 1.9 1.9 1 1.8 0.71
[93]
HepG2 POLD3
Mean 7.29
Standard deviation 0.95
Values 6.6 8
[94]
HepG2.C3A POLD3
Mean 5.94
Standard deviation 4
Values 3.1 8.8
[95]
HuH.7 POLD3
Mean 11.2
Standard deviation 6.1
Values 15 4.1 14
[96]
SNU475 POLD3
Mean 11.6
Standard deviation 3.7
Values 9 14
[97]
THLE POLD3
Mean 18.3
Standard deviation 1.6
Values 17 19
[98]
liver POLD3
Mean 4.11
Standard deviation 1.1
Values 3.6 4.3 5.6 3
[99]
ref_hepatocyte EXO1
Mean 0.669
Standard deviation 0.56
Values 1.1 1.4 0.19 0.53 0.12
[100]
HepG2 EXO1
Mean 5.53
Standard deviation 3.6
Values 3 8
[101]
HepG2.C3A EXO1
Mean 6
Standard deviation 4.2
Values 3.1 8.9
[102]
HuH.7 EXO1
Mean 13
Standard deviation 8
Values 18 3.7 17
[103]
SNU475 EXO1
Mean 16.8
Standard deviation 6.9
Values 12 22
[104]
THLE EXO1
Mean 11.5
Standard deviation 1.2
Values 11 12
[105]
liver EXO1
Mean 0.343
Standard deviation 0.28
Values 0.28 0.73 0.31 0.053