REACTOME_MET_ACTIVATES_RAS_SIGNALING Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 GRB2 Growth factor receptor-bound protein 2 [1] 0.57[2] 0.19[3] 0.16[4] -0.80[5] -0.37[6] -0.27[7]
2 SHC1 SHC-transforming protein 1 [8] 0.54[9] 0.54[10] 0.46[11] 1.29[12] 1.30[13] 0.22[14]
3 NRAS GTPase NRas [15] 0.00[16] 0.22[17] 0.48[18] -0.36[19] -0.27[20] -0.81[21]
4 MET Hepatocyte growth factor receptor [22] -0.54[23] -0.72[24] -0.25[25] 0.18[26] -0.59[27] 0.41[28]
5 HRAS GTPase HRas [29] -1.64[30] -2.55[31] -3.50[32] -2.30[33] -2.00[34] -3.22[35]
6 KRAS GTPase KRas [36] -1.14[37] -1.37[38] 0.07[39] -0.55[40] -0.38[41] 0.11[42]
7 SOS1 Son of sevenless homolog 1 [43] -0.73[44] 0.59[45] -0.06[46] -0.51[47] -0.76[48] -0.03[49]
8 RANBP9 Ran-binding protein 9 [50] 0.27[51] 0.23[52] -0.56[53] 0.33[54] 0.17[55] -0.42[56]
9 RANBP10 Ran-binding protein 10 [57] 0.83[58] 1.21[59] 0.52[60] -0.16[61] 0.59[62] 1.65[63]
10 MUC20 Mucin-20 [64] -2.83[65] -0.58[66] -2.78[67] -4.78[68] -4.55[69] 1.48[70]
11 HGF Hepatocyte growth factor [71] [72] [73] -2.65[74] 3.24[75] 0.78[76] 8.33[77]
[1]
ref_hepatocyte GRB2
Mean 20.7
Standard deviation 5.5
Values 27 26 20 14 17
[2]
HepG2 GRB2
Mean 104
Standard deviation 4.7
Values 1e+02 1.1e+02
[3]
HepG2.C3A GRB2
Mean 83.1
Standard deviation 0.44
Values 83 83
[4]
HuH.7 GRB2
Mean 86.7
Standard deviation 7.6
Values 89 78 93
[5]
SNU475 GRB2
Mean 55.7
Standard deviation 1.4
Values 55 57
[6]
THLE GRB2
Mean 58.8
Standard deviation 3.7
Values 56 61
[7]
liver GRB2
Mean 36.1
Standard deviation 16
Values 50 22 50 22
[8]
ref_hepatocyte SHC1
Mean 16.6
Standard deviation 7.2
Values 5.8 17 19 26 16
[9]
HepG2 SHC1
Mean 82
Standard deviation 0.099
Values 82 82
[10]
HepG2.C3A SHC1
Mean 84.9
Standard deviation 11
Values 77 93
[11]
HuH.7 SHC1
Mean 85.9
Standard deviation 2.4
Values 89 84 85
[12]
SNU475 SHC1
Mean 191
Standard deviation 36
Values 2.2e+02 1.7e+02
[13]
THLE SHC1
Mean 150
Standard deviation 11
Values 1.4e+02 1.6e+02
[14]
liver SHC1
Mean 40.4
Standard deviation 11
Values 37 32 56 37
[15]
ref_hepatocyte NRAS
Mean 14.4
Standard deviation 13
Values 32 23 9.3 3.3 4.6
[16]
HepG2 NRAS
Mean 49.3
Standard deviation 10
Values 42 57
[17]
HepG2.C3A NRAS
Mean 59.2
Standard deviation 18
Values 47 72
[18]
HuH.7 NRAS
Mean 75.6
Standard deviation 9.1
Values 86 70 71
[19]
SNU475 NRAS
Mean 52.9
Standard deviation 9.2
Values 59 46
[20]
THLE NRAS
Mean 44
Standard deviation 8.9
Values 38 50
[21]
liver NRAS
Mean 17.2
Standard deviation 2.6
Values 14 21 18 16
[22]
ref_hepatocyte MET
Mean 12.9
Standard deviation 12
Values 6.9 32 16 3.7 5.7
[23]
HepG2 MET
Mean 30.2
Standard deviation 2.7
Values 32 28
[24]
HepG2.C3A MET
Mean 27.5
Standard deviation 6.5
Values 23 32
[25]
HuH.7 MET
Mean 40.8
Standard deviation 7.3
Values 43 47 33
[26]
SNU475 MET
Mean 68.7
Standard deviation 7.1
Values 64 74
[27]
THLE MET
Mean 31.7
Standard deviation 2
Values 33 30
[28]
liver MET
Mean 35.9
Standard deviation 13
Values 27 46 22 48
[29]
ref_hepatocyte HRAS
Mean 11.6
Standard deviation 9
Values 4 27 11 7.4 8.8
[30]
HepG2 HRAS
Mean 12.7
Standard deviation 1.1
Values 14 12
[31]
HepG2.C3A HRAS
Mean 6.96
Standard deviation 1.3
Values 6 7.9
[32]
HuH.7 HRAS
Mean 3.85
Standard deviation 1.6
Values 3.6 2.4 5.6
[33]
SNU475 HRAS
Mean 11
Standard deviation 0.62
Values 11 11
[34]
THLE HRAS
Mean 10.7
Standard deviation 2.3
Values 9.1 12
[35]
liver HRAS
Mean 2.6
Standard deviation 1.6
Values 4.1 1.1 3.8 1.4
[36]
ref_hepatocyte KRAS
Mean 8.97
Standard deviation 7.9
Values 18 17 5.4 1.7 2.7
[37]
HepG2 KRAS
Mean 13.9
Standard deviation 3.1
Values 12 16
[38]
HepG2.C3A KRAS
Mean 12.2
Standard deviation 2.3
Values 11 14
[39]
HuH.7 KRAS
Mean 35.4
Standard deviation 4.8
Values 40 30 36
[40]
SNU475 KRAS
Mean 28.7
Standard deviation 5.5
Values 33 25
[41]
THLE KRAS
Mean 25.4
Standard deviation 1.5
Values 24 26
[42]
liver KRAS
Mean 20.4
Standard deviation 8.7
Values 33 16 19 14
[43]
ref_hepatocyte SOS1
Mean 6.81
Standard deviation 11
Values 27 1.9 2.2 1.3 1.5
[44]
HepG2 SOS1
Mean 14
Standard deviation 6.5
Values 9.4 19
[45]
HepG2.C3A SOS1
Mean 36.1
Standard deviation 3.7
Values 39 33
[46]
HuH.7 SOS1
Mean 24.6
Standard deviation 11
Values 22 37 15
[47]
SNU475 SOS1
Mean 22.5
Standard deviation 3.3
Values 25 20
[48]
THLE SOS1
Mean 14.8
Standard deviation 1.4
Values 16 14
[49]
liver SOS1
Mean 14.1
Standard deviation 3.8
Values 13 18 9.3 16
[50]
ref_hepatocyte RANBP9
Mean 5.86
Standard deviation 2.7
Values 10 4.7 4.9 3.3 6
[51]
HepG2 RANBP9
Mean 24.1
Standard deviation 3.7
Values 21 27
[52]
HepG2.C3A RANBP9
Mean 24.1
Standard deviation 1
Values 25 23
[53]
HuH.7 RANBP9
Mean 15
Standard deviation 3.6
Values 13 19 13
[54]
SNU475 RANBP9
Mean 34.5
Standard deviation 1
Values 34 35
[55]
THLE RANBP9
Mean 24.3
Standard deviation 0.021
Values 24 24
[56]
liver RANBP9
Mean 9.21
Standard deviation 2.5
Values 8.4 12 6.1 10
[57]
ref_hepatocyte RANBP10
Mean 2.39
Standard deviation 0.7
Values 1.3 2.6 2.3 3.3 2.5
[58]
HepG2 RANBP10
Mean 14.5
Standard deviation 0.52
Values 14 15
[59]
HepG2.C3A RANBP10
Mean 19.4
Standard deviation 5.6
Values 23 15
[60]
HuH.7 RANBP10
Mean 12.9
Standard deviation 2.7
Values 12 16 11
[61]
SNU475 RANBP10
Mean 10.1
Standard deviation 0.16
Values 10 10
[62]
THLE RANBP10
Mean 13.3
Standard deviation 0.12
Values 13 13
[63]
liver RANBP10
Mean 15.8
Standard deviation 5.1
Values 21 13 19 9.9
[64]
ref_hepatocyte MUC20
Mean 1.09
Standard deviation 0.95
Values 0.14 0.69 2.7 0.78 1.2
[65]
HepG2 MUC20
Mean 0.521
Standard deviation 0.04
Values 0.49 0.55
[66]
HepG2.C3A MUC20
Mean 2.56
Standard deviation 0.6
Values 2.1 3
[67]
HuH.7 MUC20
Mean 0.598
Standard deviation 0.3
Values 0.41 0.94 0.44
[68]
SNU475 MUC20
Mean 0.187
Standard deviation 0.08
Values 0.13 0.24
[69]
THLE MUC20
Mean 0.171
Standard deviation 0.084
Values 0.23 0.11
[70]
liver MUC20
Mean 6.36
Standard deviation 2.3
Values 6.2 5.3 9.6 4.3
[71]
ref_hepatocyte HGF
Mean 0.0217
Standard deviation 0.03
Values 0 0 0 0.052 0.057
[72]
HepG2 HGF
Mean 0
Standard deviation 0
Values 0 0
[73]
HepG2.C3A HGF
Mean 0
Standard deviation 0
Values 0 0
[74]
HuH.7 HGF
Mean 0.0131
Standard deviation 0.017
Values 0.033 0.0064 0
[75]
SNU475 HGF
Mean 0.963
Standard deviation 0.42
Values 1.3 0.67
[76]
THLE HGF
Mean 0.138
Standard deviation 0.061
Values 0.095 0.18
[77]
liver HGF
Mean 14.7
Standard deviation 7.2
Values 9.2 24 9.5 16