REACTOME_MET_ACTIVATES_PI3K_AKT_SIGNALING Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 GRB2 Growth factor receptor-bound protein 2 [1] 0.52[2] 0.34[3] 0.12[4] -0.73[5] -0.28[6] -1.31[7]
2 MET Hepatocyte growth factor receptor [8] -0.59[9] -0.58[10] -0.29[11] 0.25[12] -0.50[13] -0.64[14]
3 PIK3R1 Phosphatidylinositol 3-kinase regulatory subunit alpha [15] -1.15[16] -1.05[17] -0.30[18] 0.78[19] 0.82[20] 1.39[21]
4 PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform -1.05[22] 0.56[23] 0.41[24] -0.16[25] 0.58[26] 0.30[27]
5 GAB1 GRB2-associated-binding protein 1 [28] 0.63[29] 1.70[30] 1.48[31] 0.65[32] 1.04[33] 1.26[34]
6 HGF Hepatocyte growth factor [35] [36] [37] -2.68[38] 3.31[39] 0.87[40] 7.28[41]
[1]
ref_hepatocyte GRB2
Mean 20.7
Standard deviation 5.5
Values 27 26 20 14 17
[2]
HepG2 GRB2
Mean 104
Standard deviation 4.7
Values 1e+02 1.1e+02
[3]
HepG2.C3A GRB2
Mean 83.1
Standard deviation 0.44
Values 83 83
[4]
HuH.7 GRB2
Mean 86.7
Standard deviation 7.6
Values 89 78 93
[5]
SNU475 GRB2
Mean 55.7
Standard deviation 1.4
Values 55 57
[6]
THLE GRB2
Mean 58.8
Standard deviation 3.7
Values 56 61
[7]
liver GRB2
Mean 36.1
Standard deviation 16
Values 50 22 50 22
[8]
ref_hepatocyte MET
Mean 12.9
Standard deviation 12
Values 6.9 32 16 3.7 5.7
[9]
HepG2 MET
Mean 30.2
Standard deviation 2.7
Values 32 28
[10]
HepG2.C3A MET
Mean 27.5
Standard deviation 6.5
Values 23 32
[11]
HuH.7 MET
Mean 40.8
Standard deviation 7.3
Values 43 47 33
[12]
SNU475 MET
Mean 68.7
Standard deviation 7.1
Values 64 74
[13]
THLE MET
Mean 31.7
Standard deviation 2
Values 33 30
[14]
liver MET
Mean 35.9
Standard deviation 13
Values 27 46 22 48
[15]
ref_hepatocyte PIK3R1
Mean 7.45
Standard deviation 3.9
Values 4.1 7.4 4.2 8.1 14
[16]
HepG2 PIK3R1
Mean 11.9
Standard deviation 3
Values 9.8 14
[17]
HepG2.C3A PIK3R1
Mean 11.5
Standard deviation 2.6
Values 9.6 13
[18]
HuH.7 PIK3R1
Mean 23.4
Standard deviation 8.6
Values 23 32 15
[19]
SNU475 PIK3R1
Mean 57.3
Standard deviation 32
Values 80 35
[20]
THLE PIK3R1
Mean 45.5
Standard deviation 1.5
Values 44 47
[21]
liver PIK3R1
Mean 84.8
Standard deviation 47
Values 64 1e+02 32 1.4e+02
[22]
ref_hepatocyte PIK3CA
Mean 1.87
Standard deviation 0.73
Values 2.3 2.6 2.3 1.2 0.94
[23]
HepG2 PIK3CA
Mean 3.17
Standard deviation 1.6
Values 2.1 4.3
[24]
HepG2.C3A PIK3CA
Mean 8.78
Standard deviation 1.1
Values 8 9.6
[25]
HuH.7 PIK3CA
Mean 9.59
Standard deviation 2.4
Values 10 12 7
[26]
SNU475 PIK3CA
Mean 7.49
Standard deviation 0.93
Values 8.1 6.8
[27]
THLE PIK3CA
Mean 9.67
Standard deviation 0.66
Values 10 9.2
[28]
liver PIK3CA
Mean 9.99
Standard deviation 4.7
Values 6.1 15 6 13
[29]
ref_hepatocyte GAB1
Mean 0.787
Standard deviation 0.67
Values 2 0.61 0.33 0.38 0.66
[30]
HepG2 GAB1
Mean 4.28
Standard deviation 2.2
Values 2.8 5.8
[31]
HepG2.C3A GAB1
Mean 8.12
Standard deviation 2.3
Values 6.5 9.8
[32]
HuH.7 GAB1
Mean 8.48
Standard deviation 1.4
Values 10 8.1 7.3
[33]
SNU475 GAB1
Mean 5.52
Standard deviation 1.6
Values 6.6 4.4
[34]
THLE GAB1
Mean 5.62
Standard deviation 0.39
Values 5.9 5.3
[35]
liver GAB1
Mean 8.2
Standard deviation 2.5
Values 7.1 10 5.3 10
[36]
ref_hepatocyte HGF
Mean 0.0217
Standard deviation 0.03
Values 0 0 0 0.052 0.057
[37]
HepG2 HGF
Mean 0
Standard deviation 0
Values 0 0
[38]
HepG2.C3A HGF
Mean 0
Standard deviation 0
Values 0 0
[39]
HuH.7 HGF
Mean 0.0131
Standard deviation 0.017
Values 0.033 0.0064 0
[40]
SNU475 HGF
Mean 0.963
Standard deviation 0.42
Values 1.3 0.67
[41]
THLE HGF
Mean 0.138
Standard deviation 0.061
Values 0.095 0.18
[42]
liver HGF
Mean 14.7
Standard deviation 7.2
Values 9.2 24 9.5 16