REACTOME_METALLOPROTEASE_DUBS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 UBB Polyubiquitin-B [1] -0.27[2] -0.52[3] -0.65[4] -0.49[5] -0.31[6] 0.00[7]
2 RPS27A Ubiquitin-40S ribosomal protein S27a [8] [9] [10] [11] [12] [13] [14]
3 UBC Polyubiquitin-C [15] 0.18[16] 0.24[17] -0.28[18] 0.36[19] 0.06[20] 0.45[21]
4 UBA52 Ubiquitin-60S ribosomal protein L40 [22] 2.61[23] 2.47[24] 3.23[25] 1.76[26] 2.29[27] 1.22[28]
5 PSMD14 26S proteasome non-ATPase regulatory subunit 14 [29] 0.88[30] 1.34[31] 1.33[32] 1.48[33] 1.26[34] 0.33[35]
6 BABAM1 BRISC and BRCA1-A complex member 1 [36] 1.11[37] 1.27[38] 1.88[39] 1.25[40] 1.65[41] 0.41[42]
7 STAMBP STAM-binding protein [43] 3.13[44] 3.28[45] 2.61[46] 2.95[47] 3.02[48] 2.33[49]
8 UIMC1 BRCA1-A complex subunit RAP80 [50] 2.30[51] 2.49[52] 2.65[53] 2.36[54] 2.23[55] 1.58[56]
9 BRCC3 Lys-63-specific deubiquitinase BRCC36 [57] 1.46[58] 2.35[59] 1.36[60] 2.06[61] 1.95[62] 2.31[63]
10 STAM Signal transducing adapter molecule 1 [64] 2.99[65] 3.38[66] 2.14[67] 3.97[68] 3.00[69] 1.63[70]
11 KAT2B Histone acetyltransferase KAT2B [71] -0.12[72] -1.28[73] 0.80[74] 2.22[75] 2.37[76] 3.66[77]
12 EP300 Histone acetyltransferase p300 [78] 4.66[79] 4.20[80] 4.81[81] 4.86[82] 4.63[83] 4.63[84]
13 BRCA1 Breast cancer type 1 susceptibility protein [85] 3.60[86] 4.80[87] 4.91[88] 4.43[89] 4.68[90] 3.55[91]
14 MYSM1 Histone H2A deubiquitinase MYSM1 [92] 3.72[93] 4.99[94] 4.52[95] 5.02[96] 4.83[97] 4.90[98]
15 STAMBPL1 AMSH-like protease [99] -0.44[100] -4.16[101] 2.17[102] 3.04[103] 3.18[104] 1.88[105]
16 BARD1 BRCA1-associated RING domain protein 1 [106] 3.25[107] 4.18[108] 3.92[109] 4.98[110] 4.79[111] 3.75[112]
17 NLRP3 NACHT, LRR and PYD domains-containing protein 3 [113] -1.70[114] 0.49[115] -1.60[116] 0.90[117] 3.10[118] 3.47[119]
18 H2AC6 [120] [121] [122] [123] [124] [125] [126]
19 H2AC15 [127] [128] [129] [130] [131] [132] [133]
20 H2AC1 [134] [135] [136] [137] [138] [139] [140]
21 H2AC20 [141] [142] [143] [144] [145] [146] [147]
22 H2AC7 [148] [149] [150] [151] [152] [153] [154]
23 BABAM2 BRISC and BRCA1-A complex member 2 [155] [156] [157] [158] [159] [160] [161]
24 H2AC12 [162] [163] [164] [165] [166] [167] [168]
25 H2AC13 [169] [170] [171] [172] [173] [174] [175]
26 H2AC11 [176] [177] [178] [179] [180] [181] [182]
27 H2AW [183] [184] [185] [186] [187] [188] [189]
28 H2AC8 [190] [191] [192] [193] [194] [195] [196]
29 H2AC14 [197] [198] [199] [200] [201] [202] [203]
30 H2AC16 [204] [205] [206] [207] [208] [209] [210]
31 H2AC4 [211] [212] [213] [214] [215] [216] [217]
32 ABRAXAS1 BRCA1-A complex subunit Abraxas 1 [218] [219] [220] [221] [222] [223] [224]
33 H2AC17 [225] [226] [227] [228] [229] [230] [231]
34 H2AC21 [232] [233] [234] [235] [236] [237] [238]
35 ABRAXAS2 BRISC complex subunit Abraxas 2 [239] [240] [241] [242] [243] [244] [245]
[1]
ref_hepatocyte UBB
Mean 764
Standard deviation 4.8e+02
Values 3.8e+02 3.5e+02 5.3e+02 1.2e+03 1.3e+03
[2]
HepG2 UBB
Mean 368
Standard deviation 39
Values 4e+02 3.4e+02
[3]
HepG2.C3A UBB
Mean 285
Standard deviation 14
Values 2.8e+02 3e+02
[4]
HuH.7 UBB
Mean 304
Standard deviation 40
Values 2.9e+02 2.7e+02 3.5e+02
[5]
SNU475 UBB
Mean 204
Standard deviation 3.3
Values 2.1e+02 2e+02
[6]
THLE UBB
Mean 315
Standard deviation 34
Values 2.9e+02 3.4e+02
[7]
liver UBB
Mean 296
Standard deviation 1.3e+02
Values 4.3e+02 2.1e+02 3.9e+02 1.5e+02
[8]
ref_hepatocyte RPS27A
Mean 499
Standard deviation 2.2e+02
Values 6.6e+02 6.1e+02 1.7e+02 6.8e+02 3.8e+02
[9]
HepG2 RPS27A
Missing
[10]
HepG2.C3A RPS27A
Missing
[11]
HuH.7 RPS27A
Missing
[12]
SNU475 RPS27A
Missing
[13]
THLE RPS27A
Missing
[14]
liver RPS27A
Missing
[15]
ref_hepatocyte UBC
Mean 480
Standard deviation 2.8e+02
Values 1.8e+02 3.5e+02 9.1e+02 5.8e+02 3.8e+02
[16]
HepG2 UBC
Mean 314
Standard deviation 38
Values 3.4e+02 2.9e+02
[17]
HepG2.C3A UBC
Mean 302
Standard deviation 41
Values 3.3e+02 2.7e+02
[18]
HuH.7 UBC
Mean 246
Standard deviation 64
Values 2.4e+02 3.1e+02 1.9e+02
[19]
SNU475 UBC
Mean 232
Standard deviation 63
Values 2.8e+02 1.9e+02
[20]
THLE UBC
Mean 257
Standard deviation 41
Values 2.3e+02 2.9e+02
[21]
liver UBC
Mean 254
Standard deviation 78
Values 2.2e+02 3.1e+02 3.3e+02 1.6e+02
[22]
ref_hepatocyte UBA52
Mean 57.3
Standard deviation 43
Values 14 23 49 1.2e+02 81
[23]
HepG2 UBA52
Mean 203
Standard deviation 20
Values 2.2e+02 1.9e+02
[24]
HepG2.C3A UBA52
Mean 169
Standard deviation 3.3
Values 1.7e+02 1.7e+02
[25]
HuH.7 UBA52
Mean 334
Standard deviation 46
Values 3.4e+02 2.8e+02 3.7e+02
[26]
SNU475 UBA52
Mean 72.9
Standard deviation 11
Values 65 81
[27]
THLE UBA52
Mean 144
Standard deviation 15
Values 1.3e+02 1.5e+02
[28]
liver UBA52
Mean 51.7
Standard deviation 26
Values 79 32 68 28
[29]
ref_hepatocyte PSMD14
Mean 48.2
Standard deviation 36
Values 68 1e+02 24 28 19
[30]
HepG2 PSMD14
Mean 51.4
Standard deviation 7.4
Values 46 57
[31]
HepG2.C3A PSMD14
Mean 65
Standard deviation 18
Values 52 78
[32]
HuH.7 PSMD14
Mean 75.6
Standard deviation 22
Values 81 52 94
[33]
SNU475 PSMD14
Mean 50.8
Standard deviation 6.2
Values 46 55
[34]
THLE PSMD14
Mean 59.3
Standard deviation 6.5
Values 55 64
[35]
liver PSMD14
Mean 23.4
Standard deviation 12
Values 33 16 33 11
[36]
ref_hepatocyte BABAM1
Mean 25.1
Standard deviation 11
Values 9.1 20 38 31 27
[37]
HepG2 BABAM1
Mean 31.4
Standard deviation 1.1
Values 32 31
[38]
HepG2.C3A BABAM1
Mean 32.3
Standard deviation 3.5
Values 30 35
[39]
HuH.7 BABAM1
Mean 57.5
Standard deviation 17
Values 60 39 73
[40]
SNU475 BABAM1
Mean 22.6
Standard deviation 4.4
Values 26 19
[41]
THLE BABAM1
Mean 40.2
Standard deviation 2.6
Values 38 42
[42]
liver BABAM1
Mean 12.9
Standard deviation 5.9
Values 17 8.3 19 7.2
[43]
ref_hepatocyte STAMBP
Mean 5.28
Standard deviation 2.4
Values 6.2 8.1 6.5 2.6 3
[44]
HepG2 STAMBP
Mean 26.7
Standard deviation 1.8
Values 25 28
[45]
HepG2.C3A STAMBP
Mean 27.4
Standard deviation 2.9
Values 25 29
[46]
HuH.7 STAMBP
Mean 20
Standard deviation 0.55
Values 20 19 21
[47]
SNU475 STAMBP
Mean 15.4
Standard deviation 2.1
Values 17 14
[48]
THLE STAMBP
Mean 21.9
Standard deviation 1.4
Values 21 23
[49]
liver STAMBP
Mean 10.2
Standard deviation 2.9
Values 13 9.2 12 6.7
[50]
ref_hepatocyte UIMC1
Mean 5.15
Standard deviation 4.3
Values 3.4 4.5 13 3.3 2
[51]
HepG2 UIMC1
Mean 14.7
Standard deviation 0.61
Values 14 15
[52]
HepG2.C3A UIMC1
Mean 15.4
Standard deviation 0.39
Values 16 15
[53]
HuH.7 UIMC1
Mean 20.1
Standard deviation 1.6
Values 19 19 22
[54]
SNU475 UIMC1
Mean 9.94
Standard deviation 0.92
Values 9.3 11
[55]
THLE UIMC1
Mean 12.4
Standard deviation 0.38
Values 12 13
[56]
liver UIMC1
Mean 5.96
Standard deviation 1.3
Values 4.6 7.7 5.5 6
[57]
ref_hepatocyte BRCC3
Mean 5.02
Standard deviation 2.2
Values 7.3 7.5 3.1 3.2 4
[58]
HepG2 BRCC3
Mean 8.01
Standard deviation 4.4
Values 4.9 11
[59]
HepG2.C3A BRCC3
Mean 13.7
Standard deviation 6.4
Values 9.1 18
[60]
HuH.7 BRCC3
Mean 8.03
Standard deviation 1.6
Values 9.4 6.3 8.3
[61]
SNU475 BRCC3
Mean 7.86
Standard deviation 0.18
Values 7.7 8
[62]
THLE BRCC3
Mean 9.91
Standard deviation 0.42
Values 10 9.6
[63]
liver BRCC3
Mean 9.64
Standard deviation 3.8
Values 12 7.8 13 5.2
[64]
ref_hepatocyte STAM
Mean 4.67
Standard deviation 4.3
Values 3.4 4.5 12 1.7 1.7
[65]
HepG2 STAM
Mean 21.4
Standard deviation 0.48
Values 22 21
[66]
HepG2.C3A STAM
Mean 26
Standard deviation 1.5
Values 25 27
[67]
HuH.7 STAM
Mean 12.8
Standard deviation 1.6
Values 15 11 13
[68]
SNU475 STAM
Mean 27.6
Standard deviation 1.8
Values 26 29
[69]
THLE STAM
Mean 19.2
Standard deviation 2.2
Values 18 21
[70]
liver STAM
Mean 5.6
Standard deviation 0.77
Values 5.9 5.8 6.3 4.5
[71]
ref_hepatocyte KAT2B
Mean 3.02
Standard deviation 2.4
Values 0.53 4.6 0.74 3.2 6.1
[72]
HepG2 KAT2B
Mean 1.62
Standard deviation 1.1
Values 0.84 2.4
[73]
HepG2.C3A KAT2B
Mean 0.662
Standard deviation 0.012
Values 0.67 0.65
[74]
HuH.7 KAT2B
Mean 3.28
Standard deviation 0.41
Values 2.8 3.6 3.4
[75]
SNU475 KAT2B
Mean 5.31
Standard deviation 1.3
Values 6.2 4.4
[76]
THLE KAT2B
Mean 7.98
Standard deviation 1.1
Values 7.2 8.8
[77]
liver KAT2B
Mean 14.8
Standard deviation 5
Values 19 17 7.6 16
[78]
ref_hepatocyte EP300
Mean 2.46
Standard deviation 1.2
Values 3 1.8 4.4 1.4 1.8
[79]
HepG2 EP300
Mean 35.9
Standard deviation 5.7
Values 32 40
[80]
HepG2.C3A EP300
Mean 24.1
Standard deviation 1.4
Values 23 25
[81]
HuH.7 EP300
Mean 43
Standard deviation 15
Values 55 48 26
[82]
SNU475 EP300
Mean 26.9
Standard deviation 1.3
Values 28 26
[83]
THLE EP300
Mean 31.2
Standard deviation 11
Values 23 39
[84]
liver EP300
Mean 23.6
Standard deviation 8
Values 20 27 15 33
[85]
ref_hepatocyte BRCA1
Mean 1.87
Standard deviation 0.88
Values 2.7 1.4 0.59 2.6 2
[86]
HepG2 BRCA1
Mean 13.1
Standard deviation 3
Values 11 15
[87]
HepG2.C3A BRCA1
Mean 27.8
Standard deviation 18
Values 15 40
[88]
HuH.7 BRCA1
Mean 35
Standard deviation 16
Values 49 17 39
[89]
SNU475 BRCA1
Mean 15.2
Standard deviation 6.4
Values 11 20
[90]
THLE BRCA1
Mean 24.5
Standard deviation 0.48
Values 25 24
[91]
liver BRCA1
Mean 8.47
Standard deviation 9.4
Values 22 4.3 2.5 4.5
[92]
ref_hepatocyte MYSM1
Mean 1.42
Standard deviation 1
Values 3 1.9 1.1 0.41 0.69
[93]
HepG2 MYSM1
Mean 10.8
Standard deviation 4.9
Values 7.3 14
[94]
HepG2.C3A MYSM1
Mean 24.1
Standard deviation 3.1
Values 22 26
[95]
HuH.7 MYSM1
Mean 20.3
Standard deviation 4.5
Values 21 25 16
[96]
SNU475 MYSM1
Mean 17.3
Standard deviation 2.7
Values 19 15
[97]
THLE MYSM1
Mean 20.6
Standard deviation 3.6
Values 23 18
[98]
liver MYSM1
Mean 16.4
Standard deviation 5
Values 12 23 13 17
[99]
ref_hepatocyte STAMBPL1
Mean 1.4
Standard deviation 1.2
Values 0.79 3.5 1.3 0.8 0.66
[100]
HepG2 STAMBPL1
Mean 0.598
Standard deviation 0.059
Values 0.56 0.64
[101]
HepG2.C3A STAMBPL1
Mean 0.0419
Standard deviation 0.032
Values 0.019 0.064
[102]
HuH.7 STAMBPL1
Mean 3.92
Standard deviation 0.21
Values 3.7 4.1 4
[103]
SNU475 STAMBPL1
Mean 4.33
Standard deviation 2.4
Values 2.6 6
[104]
THLE STAMBPL1
Mean 6.5
Standard deviation 0.62
Values 6.1 6.9
[105]
liver STAMBPL1
Mean 2
Standard deviation 0.54
Values 1.2 2.4 2.4 2.1
[106]
ref_hepatocyte BARD1
Mean 0.427
Standard deviation 0.62
Values 0.59 1.4 0 0.1 0
[107]
HepG2 BARD1
Mean 2.35
Standard deviation 1.5
Values 1.3 3.4
[108]
HepG2.C3A BARD1
Mean 4.15
Standard deviation 3.3
Values 1.8 6.4
[109]
HuH.7 BARD1
Mean 4.04
Standard deviation 1.6
Values 5.9 3 3.3
[110]
SNU475 BARD1
Mean 5.09
Standard deviation 0.31
Values 4.9 5.3
[111]
THLE BARD1
Mean 6.04
Standard deviation 1.7
Values 4.8 7.3
[112]
liver BARD1
Mean 2.22
Standard deviation 0.7
Values 1.4 3 1.9 2.5
[113]
ref_hepatocyte NLRP3
Mean 0.117
Standard deviation 0.12
Values 0 0.11 0 0.28 0.19
[114]
HepG2 NLRP3
Mean 0.0207
Standard deviation 0.013
Values 0.011 0.03
[115]
HepG2.C3A NLRP3
Mean 0.0871
Standard deviation 0.013
Values 0.078 0.097
[116]
HuH.7 NLRP3
Mean 0.024
Standard deviation 0.036
Values 0 0.0064 0.066
[117]
SNU475 NLRP3
Mean 0.0819
Standard deviation 0.063
Values 0.037 0.13
[118]
THLE NLRP3
Mean 0.513
Standard deviation 0.15
Values 0.62 0.4
[119]
liver NLRP3
Mean 0.499
Standard deviation 0.28
Values 0.19 0.84 0.39 0.58
[120]
ref_hepatocyte H2AC6
Missing
[121]
HepG2 H2AC6
Missing
[122]
HepG2.C3A H2AC6
Missing
[123]
HuH.7 H2AC6
Missing
[124]
SNU475 H2AC6
Missing
[125]
THLE H2AC6
Missing
[126]
liver H2AC6
Missing
[127]
ref_hepatocyte H2AC15
Missing
[128]
HepG2 H2AC15
Missing
[129]
HepG2.C3A H2AC15
Missing
[130]
HuH.7 H2AC15
Missing
[131]
SNU475 H2AC15
Missing
[132]
THLE H2AC15
Missing
[133]
liver H2AC15
Missing
[134]
ref_hepatocyte H2AC1
Missing
[135]
HepG2 H2AC1
Missing
[136]
HepG2.C3A H2AC1
Missing
[137]
HuH.7 H2AC1
Missing
[138]
SNU475 H2AC1
Missing
[139]
THLE H2AC1
Missing
[140]
liver H2AC1
Missing
[141]
ref_hepatocyte H2AC20
Missing
[142]
HepG2 H2AC20
Missing
[143]
HepG2.C3A H2AC20
Missing
[144]
HuH.7 H2AC20
Missing
[145]
SNU475 H2AC20
Missing
[146]
THLE H2AC20
Missing
[147]
liver H2AC20
Missing
[148]
ref_hepatocyte H2AC7
Missing
[149]
HepG2 H2AC7
Missing
[150]
HepG2.C3A H2AC7
Missing
[151]
HuH.7 H2AC7
Missing
[152]
SNU475 H2AC7
Missing
[153]
THLE H2AC7
Missing
[154]
liver H2AC7
Missing
[155]
ref_hepatocyte BABAM2
Missing
[156]
HepG2 BABAM2
Missing
[157]
HepG2.C3A BABAM2
Missing
[158]
HuH.7 BABAM2
Missing
[159]
SNU475 BABAM2
Missing
[160]
THLE BABAM2
Missing
[161]
liver BABAM2
Missing
[162]
ref_hepatocyte H2AC12
Missing
[163]
HepG2 H2AC12
Missing
[164]
HepG2.C3A H2AC12
Missing
[165]
HuH.7 H2AC12
Missing
[166]
SNU475 H2AC12
Missing
[167]
THLE H2AC12
Missing
[168]
liver H2AC12
Missing
[169]
ref_hepatocyte H2AC13
Missing
[170]
HepG2 H2AC13
Missing
[171]
HepG2.C3A H2AC13
Missing
[172]
HuH.7 H2AC13
Missing
[173]
SNU475 H2AC13
Missing
[174]
THLE H2AC13
Missing
[175]
liver H2AC13
Missing
[176]
ref_hepatocyte H2AC11
Missing
[177]
HepG2 H2AC11
Missing
[178]
HepG2.C3A H2AC11
Missing
[179]
HuH.7 H2AC11
Missing
[180]
SNU475 H2AC11
Missing
[181]
THLE H2AC11
Missing
[182]
liver H2AC11
Missing
[183]
ref_hepatocyte H2AW
Missing
[184]
HepG2 H2AW
Missing
[185]
HepG2.C3A H2AW
Missing
[186]
HuH.7 H2AW
Missing
[187]
SNU475 H2AW
Missing
[188]
THLE H2AW
Missing
[189]
liver H2AW
Missing
[190]
ref_hepatocyte H2AC8
Missing
[191]
HepG2 H2AC8
Missing
[192]
HepG2.C3A H2AC8
Missing
[193]
HuH.7 H2AC8
Missing
[194]
SNU475 H2AC8
Missing
[195]
THLE H2AC8
Missing
[196]
liver H2AC8
Missing
[197]
ref_hepatocyte H2AC14
Missing
[198]
HepG2 H2AC14
Missing
[199]
HepG2.C3A H2AC14
Missing
[200]
HuH.7 H2AC14
Missing
[201]
SNU475 H2AC14
Missing
[202]
THLE H2AC14
Missing
[203]
liver H2AC14
Missing
[204]
ref_hepatocyte H2AC16
Missing
[205]
HepG2 H2AC16
Missing
[206]
HepG2.C3A H2AC16
Missing
[207]
HuH.7 H2AC16
Missing
[208]
SNU475 H2AC16
Missing
[209]
THLE H2AC16
Missing
[210]
liver H2AC16
Missing
[211]
ref_hepatocyte H2AC4
Missing
[212]
HepG2 H2AC4
Missing
[213]
HepG2.C3A H2AC4
Missing
[214]
HuH.7 H2AC4
Missing
[215]
SNU475 H2AC4
Missing
[216]
THLE H2AC4
Missing
[217]
liver H2AC4
Missing
[218]
ref_hepatocyte ABRAXAS1
Missing
[219]
HepG2 ABRAXAS1
Missing
[220]
HepG2.C3A ABRAXAS1
Missing
[221]
HuH.7 ABRAXAS1
Missing
[222]
SNU475 ABRAXAS1
Missing
[223]
THLE ABRAXAS1
Missing
[224]
liver ABRAXAS1
Missing
[225]
ref_hepatocyte H2AC17
Missing
[226]
HepG2 H2AC17
Missing
[227]
HepG2.C3A H2AC17
Missing
[228]
HuH.7 H2AC17
Missing
[229]
SNU475 H2AC17
Missing
[230]
THLE H2AC17
Missing
[231]
liver H2AC17
Missing
[232]
ref_hepatocyte H2AC21
Missing
[233]
HepG2 H2AC21
Missing
[234]
HepG2.C3A H2AC21
Missing
[235]
HuH.7 H2AC21
Missing
[236]
SNU475 H2AC21
Missing
[237]
THLE H2AC21
Missing
[238]
liver H2AC21
Missing
[239]
ref_hepatocyte ABRAXAS2
Missing
[240]
HepG2 ABRAXAS2
Missing
[241]
HepG2.C3A ABRAXAS2
Missing
[242]
HuH.7 ABRAXAS2
Missing
[243]
SNU475 ABRAXAS2
Missing
[244]
THLE ABRAXAS2
Missing
[245]
liver ABRAXAS2
Missing