REACTOME_METABOLISM_OF_STEROIDS |
Return to index |
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Order |
Gene |
Description |
ref_hepatocyte |
HepG2 |
HepG2.C3A |
HuH.7 |
SNU475 |
THLE |
liver |
1 |
ALB |
Serum albumin |
[1] |
-0.77[2] |
0.07[3] |
-0.92[4] |
-8.54[5] |
-7.84[6] |
-0.05[7] |
2 |
GC |
Vitamin D-binding protein |
[8] |
-9.13[9] |
-10.82[10] |
-0.45[11] |
-8.71[12] |
-7.93[13] |
-0.33[14] |
3 |
AKR1C1 |
Aldo-keto reductase family 1 member C1 |
[15] |
-0.24[16] |
-2.34[17] |
-5.11[18] |
0.66[19] |
-3.61[20] |
-4.15[21] |
4 |
AKR1C3 |
Aldo-keto reductase family 1 member C3 |
[22] |
0.24[23] |
-0.91[24] |
-6.62[25] |
3.90[26] |
-2.65[27] |
-2.11[28] |
5 |
SCP2 |
Non-specific lipid-transfer protein |
[29] |
-1.33[30] |
-1.97[31] |
-0.78[32] |
0.09[33] |
0.46[34] |
0.42[35] |
6 |
SCD |
Acyl-CoA desaturase |
[36] |
1.88[37] |
1.94[38] |
3.65[39] |
0.54[40] |
0.14[41] |
0.58[42] |
7 |
EBP |
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase |
[43] |
-1.80[44] |
-1.58[45] |
0.17[46] |
-1.23[47] |
0.00[48] |
-1.31[49] |
8 |
SERPINA6 |
Corticosteroid-binding globulin |
[50] |
-0.27[51] |
-1.13[52] |
-1.91[53] |
-8.92[54] |
-7.78[55] |
-0.67[56] |
9 |
FDPS |
Farnesyl pyrophosphate synthase |
[57] |
-0.46[58] |
-0.61[59] |
0.62[60] |
0.57[61] |
0.98[62] |
-1.52[63] |
10 |
AKR1C2 |
Aldo-keto reductase family 1 member C2 |
[64] |
1.62[65] |
-2.20[66] |
-3.89[67] |
3.01[68] |
-2.42[69] |
-1.08[70] |
11 |
DHCR24 |
Delta(24)-sterol reductase |
[71] |
1.95[72] |
1.07[73] |
2.35[74] |
0.93[75] |
2.22[76] |
1.62[77] |
12 |
RAN |
GTP-binding nuclear protein Ran |
[78] |
2.14[79] |
0.50[80] |
0.78[81] |
2.37[82] |
3.12[83] |
-1.86[84] |
13 |
CYP27A1 |
Sterol 26-hydroxylase, mitochondrial |
[85] |
0.43[86] |
-0.56[87] |
-2.71[88] |
-1.04[89] |
-2.07[90] |
0.17[91] |
14 |
HSD11B1 |
Corticosteroid 11-beta-dehydrogenase isozyme 1 |
[92] |
-11.29[93] |
-12.92[94] |
-14.18[95] |
-5.85[96] |
0.68[97] |
-0.18[98] |
15 |
HMGCS1 |
Hydroxymethylglutaryl-CoA synthase, cytoplasmic |
[99] |
-1.30[100] |
0.17[101] |
2.49[102] |
-0.76[103] |
-0.49[104] |
-0.16[105] |
16 |
MSMO1 |
Methylsterol monooxygenase 1 |
[106] |
-1.06[107] |
0.17[108] |
1.47[109] |
-0.70[110] |
0.62[111] |
0.60[112] |
17 |
AKR1C4 |
Aldo-keto reductase family 1 member C4 |
[113] |
-6.55[114] |
-5.97[115] |
-5.62[116] |
-7.15[117] |
-12.11[118] |
-0.80[119] |
18 |
FDFT1 |
Squalene synthase |
[120] |
0.75[121] |
0.93[122] |
1.42[123] |
-0.25[124] |
1.32[125] |
-0.87[126] |
19 |
HSD17B4 |
Peroxisomal multifunctional enzyme type 2 |
[127] |
1.07[128] |
-0.34[129] |
0.34[130] |
1.52[131] |
2.71[132] |
0.85[133] |
20 |
SLC27A5 |
Bile acyl-CoA synthetase |
[134] |
-2.93[135] |
-3.46[136] |
-4.12[137] |
-3.96[138] |
-5.95[139] |
0.71[140] |
21 |
ACAT2 |
Acetyl-CoA acetyltransferase, cytosolic |
[141] |
0.36[142] |
0.61[143] |
1.06[144] |
-0.09[145] |
0.96[146] |
-0.65[147] |
22 |
SUMO2 |
Small ubiquitin-related modifier 2 |
[148] |
2.54[149] |
0.98[150] |
1.95[151] |
2.88[152] |
3.38[153] |
-1.50[154] |
23 |
SLC27A2 |
Very long-chain acyl-CoA synthetase |
[155] |
-1.02[156] |
-2.64[157] |
-1.96[158] |
-0.55[159] |
-3.95[160] |
1.24[161] |
24 |
INSIG1 |
Insulin-induced gene 1 protein |
[162] |
-8.37[163] |
-9.93[164] |
0.77[165] |
-0.59[166] |
-0.97[167] |
1.20[168] |
25 |
CYP51A1 |
Lanosterol 14-alpha demethylase |
[169] |
-0.20[170] |
0.43[171] |
1.30[172] |
1.09[173] |
1.27[174] |
0.89[175] |
26 |
BAAT |
Bile acid-CoA:amino acid N-acyltransferase |
[176] |
-3.00[177] |
-4.16[178] |
-5.58[179] |
-4.73[180] |
-5.53[181] |
1.83[182] |
27 |
IDI1 |
Isopentenyl-diphosphate Delta-isomerase 1 |
[183] |
-0.34[184] |
1.37[185] |
0.90[186] |
1.96[187] |
1.26[188] |
0.40[189] |
28 |
HSD17B11 |
Estradiol 17-beta-dehydrogenase 11 |
[190] |
1.04[191] |
0.75[192] |
1.67[193] |
1.23[194] |
1.23[195] |
0.09[196] |
29 |
KPNB1 |
Importin subunit beta-1 |
[197] |
3.43[198] |
1.81[199] |
3.04[200] |
4.72[201] |
4.85[202] |
-0.47[203] |
30 |
SLC10A1 |
Sodium/bile acid cotransporter |
[204] |
-7.30[205] |
-9.45[206] |
-9.99[207] |
-8.45[208] |
-9.30[209] |
-0.32[210] |
31 |
HSD17B2 |
Estradiol 17-beta-dehydrogenase 2 |
[211] |
-0.06[212] |
-0.39[213] |
0.13[214] |
-6.16[215] |
-3.85[216] |
-0.48[217] |
32 |
SLCO1B1 |
Solute carrier organic anion transporter family member 1B1 |
[218] |
-12.66[219] |
-10.65[220] |
-4.49[221] |
-8.83[222] |
[223] |
1.65[224] |
33 |
CYP8B1 |
7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase |
[225] |
-5.71[226] |
-4.94[227] |
-7.93[228] |
-6.46[229] |
-7.77[230] |
2.53[231] |
34 |
SQLE |
Squalene monooxygenase |
[232] |
0.64[233] |
1.45[234] |
2.12[235] |
1.37[236] |
1.31[237] |
-0.23[238] |
35 |
DHCR7 |
7-dehydrocholesterol reductase |
[239] |
1.50[240] |
1.45[241] |
2.64[242] |
0.89[243] |
1.64[244] |
1.20[245] |
36 |
SEC23A |
Protein transport protein Sec23A |
[246] |
4.44[247] |
1.46[248] |
3.44[249] |
4.44[250] |
4.22[251] |
1.14[252] |
37 |
HSD3B7 |
3 beta-hydroxysteroid dehydrogenase type 7 |
[253] |
1.28[254] |
0.36[255] |
-1.83[256] |
0.06[257] |
0.18[258] |
0.42[259] |
38 |
SREBF1 |
Sterol regulatory element-binding protein 1 |
[260] |
1.74[261] |
0.25[262] |
1.73[263] |
1.98[264] |
2.68[265] |
0.58[266] |
39 |
TSPO |
Translocator protein |
[267] |
0.19[268] |
-2.17[269] |
-0.68[270] |
2.74[271] |
3.24[272] |
-1.66[273] |
40 |
AKR1D1 |
3-oxo-5-beta-steroid 4-dehydrogenase |
[274] |
-0.57[275] |
-0.98[276] |
-2.74[277] |
-6.59[278] |
-6.30[279] |
-0.19[280] |
41 |
TM7SF2 |
Delta(14)-sterol reductase |
[281] |
1.10[282] |
0.24[283] |
0.84[284] |
0.97[285] |
-0.31[286] |
0.12[287] |
42 |
PMVK |
Phosphomevalonate kinase |
[288] |
-0.03[289] |
-1.73[290] |
0.44[291] |
1.47[292] |
1.74[293] |
-2.09[294] |
43 |
OSBPL9 |
Oxysterol-binding protein-related protein 9 |
[295] |
2.52[296] |
1.17[297] |
2.15[298] |
4.15[299] |
4.27[300] |
0.88[301] |
44 |
NR1H4 |
Bile acid receptor |
[302] |
0.91[303] |
-0.28[304] |
2.45[305] |
-4.53[306] |
-4.04[307] |
0.60[308] |
45 |
HSD17B12 |
Very-long-chain 3-oxoacyl-CoA reductase |
[309] |
1.31[310] |
0.79[311] |
2.30[312] |
1.38[313] |
2.97[314] |
1.08[315] |
46 |
MVD |
Diphosphomevalonate decarboxylase |
[316] |
1.26[317] |
1.97[318] |
2.09[319] |
1.12[320] |
1.66[321] |
-0.36[322] |
47 |
INSIG2 |
Insulin-induced gene 2 protein |
[323] |
2.64[324] |
1.89[325] |
0.95[326] |
1.20[327] |
2.36[328] |
-0.99[329] |
48 |
NSDHL |
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating |
[330] |
0.69[331] |
-0.12[332] |
0.22[333] |
1.74[334] |
1.70[335] |
-0.58[336] |
49 |
ACOX2 |
Peroxisomal acyl-coenzyme A oxidase 2 |
[337] |
0.10[338] |
-0.36[339] |
0.32[340] |
-4.35[341] |
-1.51[342] |
1.21[343] |
50 |
LGMN |
Legumain |
[344] |
2.20[345] |
-0.38[346] |
1.18[347] |
3.45[348] |
3.45[349] |
0.31[350] |
51 |
FASN |
Fatty acid synthase |
[351] |
4.91[352] |
3.78[353] |
5.28[354] |
4.25[355] |
4.80[356] |
2.59[357] |
52 |
LSS |
Lanosterol synthase |
[358] |
1.87[359] |
2.20[360] |
2.08[361] |
2.63[362] |
2.74[363] |
1.14[364] |
53 |
SLCO1B3 |
Solute carrier organic anion transporter family member 1B3 |
[365] |
-5.20[366] |
-5.56[367] |
0.24[368] |
-7.08[369] |
-6.69[370] |
2.02[371] |
54 |
HSD17B14 |
17-beta-hydroxysteroid dehydrogenase 14 |
[372] |
-2.39[373] |
-7.78[374] |
-0.04[375] |
-1.01[376] |
-2.75[377] |
-3.18[378] |
55 |
GPAM |
Glycerol-3-phosphate acyltransferase 1, mitochondrial |
[379] |
3.42[380] |
3.12[381] |
2.81[382] |
0.21[383] |
4.87[384] |
2.75[385] |
56 |
HSD17B7 |
3-keto-steroid reductase |
[386] |
-0.71[387] |
-0.63[388] |
0.33[389] |
0.14[390] |
0.29[391] |
-0.70[392] |
57 |
HMGCR |
3-hydroxy-3-methylglutaryl-coenzyme A reductase |
[393] |
1.95[394] |
2.93[395] |
4.14[396] |
3.21[397] |
3.42[398] |
1.46[399] |
58 |
MVK |
Mevalonate kinase |
[400] |
0.20[401] |
0.79[402] |
1.17[403] |
0.30[404] |
0.60[405] |
0.33[406] |
59 |
RXRA |
Retinoic acid receptor RXR-alpha |
[407] |
2.46[408] |
0.48[409] |
2.26[410] |
3.53[411] |
3.72[412] |
2.23[413] |
60 |
ELOVL6 |
Elongation of very long chain fatty acids protein 6 |
[414] |
-0.25[415] |
1.04[416] |
2.06[417] |
2.42[418] |
3.65[419] |
0.44[420] |
61 |
ABCC3 |
Canalicular multispecific organic anion transporter 2 |
[421] |
3.60[422] |
1.14[423] |
0.44[424] |
3.79[425] |
3.72[426] |
2.72[427] |
62 |
STARD4 |
StAR-related lipid transfer protein 4 |
[428] |
-0.91[429] |
0.42[430] |
0.67[431] |
0.90[432] |
0.60[433] |
-0.72[434] |
63 |
STARD5 |
StAR-related lipid transfer protein 5 |
[435] |
-3.48[436] |
-4.28[437] |
-6.27[438] |
-1.58[439] |
-1.41[440] |
-0.21[441] |
64 |
OSBP |
Oxysterol-binding protein 1 |
[442] |
2.70[443] |
1.11[444] |
3.58[445] |
3.99[446] |
4.37[447] |
1.91[448] |
65 |
STARD3NL |
STARD3 N-terminal-like protein |
[449] |
2.42[450] |
0.56[451] |
1.39[452] |
3.69[453] |
3.96[454] |
-1.60[455] |
66 |
MBTPS1 |
Membrane-bound transcription factor site-1 protease |
[456] |
4.10[457] |
2.14[458] |
3.07[459] |
4.91[460] |
5.48[461] |
1.40[462] |
67 |
AMACR |
Alpha-methylacyl-CoA racemase |
[463] |
-1.35[464] |
-3.11[465] |
-0.72[466] |
-1.06[467] |
-0.96[468] |
-1.74[469] |
68 |
FDX1 |
Adrenodoxin, mitochondrial |
[470] |
1.81[471] |
-0.40[472] |
-0.99[473] |
3.23[474] |
3.66[475] |
0.89[476] |
69 |
SEC24C |
Protein transport protein Sec24C |
[477] |
4.02[478] |
2.65[479] |
2.89[480] |
5.15[481] |
5.15[482] |
1.39[483] |
70 |
SAR1B |
GTP-binding protein SAR1b |
[484] |
2.25[485] |
1.69[486] |
2.48[487] |
3.52[488] |
4.46[489] |
2.94[490] |
71 |
UBE2I |
SUMO-conjugating enzyme UBC9 |
[491] |
3.80[492] |
1.70[493] |
3.02[494] |
3.85[495] |
4.93[496] |
-0.47[497] |
72 |
LBR |
Lamin-B receptor |
[498] |
3.25[499] |
2.19[500] |
3.98[501] |
4.86[502] |
4.42[503] |
0.86[504] |
73 |
NFYC |
Nuclear transcription factor Y subunit gamma |
[505] |
2.21[506] |
0.30[507] |
1.32[508] |
3.27[509] |
3.08[510] |
-0.35[511] |
74 |
SREBF2 |
Sterol regulatory element-binding protein 2 |
[512] |
3.77[513] |
2.85[514] |
4.97[515] |
3.19[516] |
3.99[517] |
1.56[518] |
75 |
SRD5A1 |
3-oxo-5-alpha-steroid 4-dehydrogenase 1 |
[519] |
0.50[520] |
-1.17[521] |
0.79[522] |
2.46[523] |
3.44[524] |
1.27[525] |
76 |
SEC24D |
Protein transport protein Sec24D |
[526] |
2.84[527] |
1.90[528] |
2.81[529] |
4.51[530] |
4.71[531] |
1.90[532] |
77 |
ACOT8 |
Acyl-coenzyme A thioesterase 8 |
[533] |
1.57[534] |
0.27[535] |
1.25[536] |
2.57[537] |
2.59[538] |
-0.78[539] |
78 |
SCAP |
Sterol regulatory element-binding
protein cleavage-activating protein |
3.82[540] |
2.27[541] |
3.82[542] |
3.68[543] |
4.95[544] |
1.91[545] |
79 |
CARM1 |
Histone-arginine methyltransferase CARM1 |
[546] |
3.96[547] |
1.64[548] |
2.90[549] |
3.27[550] |
4.58[551] |
-0.94[552] |
80 |
FDXR |
NADPH:adrenodoxin oxidoreductase, mitochondrial |
[553] |
5.12[554] |
2.67[555] |
0.46[556] |
1.62[557] |
3.22[558] |
-1.83[559] |
81 |
CYP39A1 |
24-hydroxycholesterol 7-alpha-hydroxylase |
[560] |
-2.55[561] |
-4.51[562] |
1.07[563] |
-1.41[564] |
1.06[565] |
0.56[566] |
82 |
AKR1B1 |
Aldose reductase |
[567] |
5.19[568] |
2.33[569] |
-1.22[570] |
6.49[571] |
7.85[572] |
-1.00[573] |
83 |
ARV1 |
Protein ARV1 |
[574] |
0.69[575] |
-0.50[576] |
0.15[577] |
2.56[578] |
2.96[579] |
-0.49[580] |
84 |
OSBPL2 |
Oxysterol-binding protein-related protein 2 |
[581] |
3.71[582] |
1.73[583] |
2.04[584] |
4.24[585] |
3.89[586] |
0.55[587] |
85 |
SRD5A2 |
3-oxo-5-alpha-steroid 4-dehydrogenase 2 |
[588] |
-6.18[589] |
-7.14[590] |
-6.27[591] |
-8.82[592] |
-8.27[593] |
-0.19[594] |
86 |
SEC24A |
Protein transport protein Sec24A |
[595] |
3.71[596] |
2.45[597] |
4.01[598] |
5.11[599] |
4.87[600] |
2.49[601] |
87 |
STARD3 |
StAR-related lipid transfer protein 3 |
[602] |
3.51[603] |
1.54[604] |
2.81[605] |
3.81[606] |
4.31[607] |
0.23[608] |
88 |
SEC24B |
Protein transport protein Sec24B |
[609] |
2.69[610] |
1.25[611] |
2.28[612] |
3.98[613] |
5.06[614] |
2.17[615] |
89 |
ACACB |
Acetyl-CoA carboxylase 2 |
[616] |
1.64[617] |
0.84[618] |
1.90[619] |
1.75[620] |
2.56[621] |
4.27[622] |
90 |
CYP21A2 |
Steroid 21-hydroxylase |
[623] |
-3.35[624] |
-3.20[625] |
-6.63[626] |
-0.71[627] |
-5.50[628] |
-0.19[629] |
91 |
NFYB |
Nuclear transcription factor Y subunit beta |
[630] |
1.87[631] |
1.71[632] |
2.01[633] |
3.91[634] |
4.77[635] |
0.08[636] |
92 |
TBL1XR1 |
F-box-like/WD repeat-containing protein TBL1XR1 |
[637] |
3.59[638] |
2.36[639] |
3.94[640] |
5.93[641] |
6.01[642] |
2.95[643] |
93 |
TBL1X |
F-box-like/WD repeat-containing protein TBL1X |
[644] |
3.85[645] |
2.48[646] |
4.98[647] |
-0.88[648] |
5.13[649] |
1.83[650] |
94 |
CYP7A1 |
Cholesterol 7-alpha-monooxygenase |
[651] |
-1.83[652] |
-5.94[653] |
-8.53[654] |
-6.45[655] |
[656] |
-2.87[657] |
95 |
PPARA |
Peroxisome proliferator-activated receptor alpha |
[658] |
3.18[659] |
2.39[660] |
4.18[661] |
3.56[662] |
3.24[663] |
4.23[664] |
96 |
NFYA |
Nuclear transcription factor Y subunit alpha |
[665] |
4.06[666] |
2.50[667] |
3.32[668] |
4.96[669] |
4.93[670] |
0.55[671] |
97 |
MED1 |
Mediator of RNA polymerase II transcription subunit 1 |
[672] |
5.06[673] |
2.61[674] |
4.45[675] |
5.72[676] |
6.40[677] |
1.36[678] |
98 |
GGPS1 |
Geranylgeranyl pyrophosphate synthase |
[679] |
2.72[680] |
2.20[681] |
3.11[682] |
5.13[683] |
4.01[684] |
0.43[685] |
99 |
SP1 |
Transcription factor Sp1 |
[686] |
4.33[687] |
2.80[688] |
4.80[689] |
6.19[690] |
6.39[691] |
2.24[692] |
100 |
PIAS4 |
E3 SUMO-protein ligase PIAS4 |
[693] |
2.75[694] |
0.50[695] |
2.18[696] |
2.99[697] |
3.62[698] |
-0.33[699] |
101 |
ACACA |
Acetyl-CoA carboxylase 1 |
[700] |
4.96[701] |
3.53[702] |
5.38[703] |
6.10[704] |
5.81[705] |
3.44[706] |
102 |
MBTPS2 |
Membrane-bound transcription factor site-2 protease |
[707] |
3.46[708] |
2.04[709] |
3.76[710] |
5.61[711] |
6.04[712] |
1.64[713] |
103 |
CYP2R1 |
Vitamin D 25-hydroxylase |
[714] |
-1.47[715] |
-1.45[716] |
1.70[717] |
2.19[718] |
2.20[719] |
-0.79[720] |
104 |
NCOA6 |
Nuclear receptor coactivator 6 |
[721] |
4.72[722] |
2.79[723] |
3.93[724] |
6.08[725] |
5.85[726] |
1.49[727] |
105 |
SRD5A3 |
Polyprenol reductase |
[728] |
3.17[729] |
1.00[730] |
2.04[731] |
3.49[732] |
4.22[733] |
0.52[734] |
106 |
TGS1 |
Trimethylguanosine synthase |
[735] |
3.10[736] |
1.77[737] |
3.25[738] |
5.24[739] |
5.59[740] |
1.06[741] |
107 |
NCOA1 |
Nuclear receptor coactivator 1 |
[742] |
2.98[743] |
1.77[744] |
2.90[745] |
5.31[746] |
5.28[747] |
2.74[748] |
108 |
OSBPL1A |
Oxysterol-binding protein-related protein 1 |
[749] |
-2.86[750] |
-5.84[751] |
2.34[752] |
5.42[753] |
5.65[754] |
1.74[755] |
109 |
ABCB11 |
Bile salt export pump |
[756] |
-4.28[757] |
[758] |
-3.82[759] |
-2.00[760] |
[761] |
4.87[762] |
110 |
HSD17B1 |
Estradiol 17-beta-dehydrogenase 1 |
[763] |
3.31[764] |
2.18[765] |
2.52[766] |
3.48[767] |
3.74[768] |
-0.35[769] |
111 |
CREBBP |
CREB-binding protein |
[770] |
5.41[771] |
2.85[772] |
4.40[773] |
6.28[774] |
6.80[775] |
3.32[776] |
112 |
CYP7B1 |
25-hydroxycholesterol 7-alpha-hydroxylase |
[777] |
-5.52[778] |
-6.01[779] |
[780] |
-5.51[781] |
-1.26[782] |
2.35[783] |
113 |
MTF1 |
Metal regulatory transcription factor 1 |
[784] |
4.03[785] |
2.11[786] |
3.62[787] |
5.67[788] |
6.21[789] |
2.06[790] |
114 |
CHD9 |
Chromodomain-helicase-DNA-binding protein 9 |
[791] |
3.84[792] |
4.16[793] |
4.34[794] |
5.90[795] |
7.44[796] |
5.01[797] |
115 |
STAR |
Steroidogenic acute regulatory protein, mitochondrial |
[798] |
3.27[799] |
0.91[800] |
-1.81[801] |
0.37[802] |
3.30[803] |
-3.41[804] |
116 |
NCOA2 |
Nuclear receptor coactivator 2 |
[805] |
4.09[806] |
3.13[807] |
5.90[808] |
6.72[809] |
5.53[810] |
4.69[811] |
117 |
CYP19A1 |
Aromatase |
[812] |
4.44[813] |
3.69[814] |
-1.83[815] |
1.87[816] |
-0.06[817] |
-6.25[818] |
118 |
POMC |
Pro-opiomelanocortin |
[819] |
[820] |
-7.63[821] |
[822] |
[823] |
-3.08[824] |
-2.11[825] |
119 |
OSBPL3 |
Oxysterol-binding protein-related protein 3 |
[826] |
6.15[827] |
4.63[828] |
5.31[829] |
6.16[830] |
7.10[831] |
0.02[832] |
120 |
AKR1B15 |
Aldo-keto reductase family 1 member B15 |
[833] |
2.94[834] |
0.36[835] |
-3.06[836] |
4.88[837] |
-0.87[838] |
-2.61[839] |
121 |
CYP11A1 |
Cholesterol side-chain cleavage enzyme, mitochondrial |
[840] |
1.85[841] |
-2.44[842] |
[843] |
0.26[844] |
4.83[845] |
0.55[846] |
122 |
OSBPL6 |
Oxysterol-binding protein-related protein 6 |
[847] |
-0.33[848] |
-2.60[849] |
4.83[850] |
3.11[851] |
8.12[852] |
2.38[853] |
123 |
HSD11B2 |
Corticosteroid 11-beta-dehydrogenase isozyme 2 |
[854] |
4.71[855] |
2.98[856] |
3.08[857] |
1.24[858] |
-0.59[859] |
0.73[860] |
124 |
CYP24A1 |
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial |
[861] |
10.65[862] |
4.01[863] |
-0.69[864] |
7.63[865] |
1.34[866] |
-7.02[867] |
125 |
VDR |
Vitamin D3 receptor |
[868] |
2.35[869] |
1.00[870] |
2.57[871] |
5.85[872] |
7.71[873] |
0.56[874] |
126 |
SMARCD3 |
SWI/SNF-related matrix-associated
actin-dependent regulator of chromatin subfamily D
member 3 |
3.98[875] |
0.54[876] |
3.53[877] |
6.78[878] |
7.49[879] |
1.45[880] |
127 |
OSBPL7 |
Oxysterol-binding protein-related protein 7 |
[881] |
4.80[882] |
3.74[883] |
-1.19[884] |
6.46[885] |
7.22[886] |
0.97[887] |
128 |
HSD17B3 |
Testosterone 17-beta-dehydrogenase 3 |
[888] |
-0.69[889] |
-2.50[890] |
3.03[891] |
3.46[892] |
-1.93[893] |
0.96[894] |
129 |
IDI2 |
Isopentenyl-diphosphate delta-isomerase 2 |
[895] |
3.27[896] |
2.37[897] |
3.28[898] |
6.29[899] |
5.34[900] |
0.59[901] |
130 |
PTGIS |
Prostacyclin synthase |
[902] |
0.95[903] |
0.30[904] |
5.21[905] |
4.64[906] |
11.10[907] |
4.92[908] |
131 |
CYP17A1 |
Steroid 17-alpha-hydroxylase/17,20 lyase |
[909] |
-0.23[910] |
2.04[911] |
-0.45[912] |
-2.22[913] |
-1.65[914] |
1.73[915] |
132 |
HSD3B1 |
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 |
[916] |
-2.60[917] |
-5.03[918] |
2.96[919] |
[920] |
1.02[921] |
-2.85[922] |
133 |
SLCO1A2 |
Solute carrier organic anion transporter family member 1A2 |
[923] |
1.05[924] |
-0.37[925] |
8.48[926] |
6.94[927] |
2.15[928] |
4.58[929] |
134 |
CGA |
Glycoprotein hormones alpha chain |
[930] |
[931] |
[932] |
-0.68[933] |
0.00[934] |
-0.79[935] |
-4.02[936] |
135 |
LRP2 |
Low-density lipoprotein receptor-related protein 2 |
[937] |
4.82[938] |
-0.29[939] |
9.33[940] |
1.24[941] |
1.49[942] |
6.30[943] |
136 |
CYP27B1 |
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial |
[944] |
5.19[945] |
4.85[946] |
5.18[947] |
4.71[948] |
5.97[949] |
1.75[950] |
137 |
CYP46A1 |
Cholesterol 24-hydroxylase |
[951] |
-1.28[952] |
-1.71[953] |
-1.80[954] |
0.96[955] |
2.68[956] |
2.34[957] |
138 |
HSD3B2 |
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 |
[958] |
-1.07[959] |
[960] |
0.84[961] |
[962] |
1.81[963] |
0.86[964] |
139 |
CH25H |
Cholesterol 25-hydroxylase |
[965] |
-0.62[966] |
[967] |
-1.11[968] |
11.74[969] |
5.75[970] |
3.18[971] |
140 |
CUBN |
Cubilin |
[972] |
3.74[973] |
3.46[974] |
2.65[975] |
8.82[976] |
7.80[977] |
4.79[978] |
141 |
LHB |
Lutropin subunit beta |
[979] |
[980] |
[981] |
[982] |
[983] |
[984] |
[985] |
142 |
FABP6 |
Gastrotropin |
[986] |
[987] |
[988] |
[989] |
[990] |
[991] |
[992] |
143 |
SLC51A |
Organic solute transporter subunit alpha |
[993] |
[994] |
[995] |
[996] |
[997] |
[998] |
[999] |
144 |
FDX2 |
Ferredoxin-2, mitochondrial |
[1000] |
[1001] |
[1002] |
[1003] |
[1004] |
[1005] |
[1006] |
145 |
TSPOAP1 |
Peripheral-type benzodiazepine receptor-associated protein 1 |
[1007] |
[1008] |
[1009] |
[1010] |
[1011] |
[1012] |
[1013] |
146 |
STARD6 |
StAR-related lipid transfer protein 6 |
[1014] |
[1015] |
[1016] |
[1017] |
[1018] |
[1019] |
[1020] |
147 |
SLC51B |
Organic solute transporter subunit beta |
[1021] |
[1022] |
[1023] |
[1024] |
[1025] |
[1026] |
[1027] |
148 |
SLC10A2 |
Ileal sodium/bile acid cotransporter |
[1028] |
[1029] |
[1030] |
[1031] |
[1032] |
[1033] |
[1034] |
149 |
SC5D |
Lathosterol oxidase |
[1035] |
[1036] |
[1037] |
[1038] |
[1039] |
[1040] |
[1041] |
150 |
CYP11B2 |
Cytochrome P450 11B2, mitochondrial |
[1042] |
[1043] |
[1044] |
[1045] |
[1046] |
[1047] |
[1048] |
151 |
HELZ2 |
Helicase with zinc finger domain 2 |
[1049] |
[1050] |
[1051] |
[1052] |
[1053] |
[1054] |
[1055] |
152 |
PLPP6 |
Phospholipid phosphatase 6 |
[1056] |
[1057] |
[1058] |
[1059] |
[1060] |
[1061] |
[1062] |
153 |
CYP11B1 |
Cytochrome P450 11B1, mitochondrial |
[1063] |
[1064] |
[1065] |
[1066] |
[1067] |
[1068] |
[1069] |
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