REACTOME_METABOLISM_OF_NITRIC_OXIDE_NOS3_ACTIVATION_AND_REGULATION Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 HSP90AA1 Heat shock protein HSP 90-alpha [1] -0.24[2] 0.11[3] -0.08[4] -0.17[5] -0.07[6] -0.85[7]
2 AKT1 RAC-alpha serine/threonine-protein kinase [8] 0.48[9] -0.36[10] -0.87[11] -0.31[12] 0.12[13] 0.16[14]
3 SPR Sepiapterin reductase [15] -0.96[16] -0.87[17] -1.82[18] -2.32[19] -2.84[20] -0.41[21]
4 CALM1 Calmodulin-1 [22] 0.48[23] -0.10[24] 0.94[25] 1.33[26] 1.01[27] 2.03[28]
5 CAV1 Caveolin-1 [29] -6.43[30] -9.87[31] -3.03[32] 1.12[33] 0.17[34] -1.59[35]
6 NOSIP Nitric oxide synthase-interacting protein [36] -0.53[37] -0.84[38] 0.10[39] -1.22[40] -0.73[41] -0.90[42]
7 LYPLA1 Acyl-protein thioesterase 1 [43] 0.49[44] 0.54[45] 0.17[46] -0.10[47] 0.15[48] 0.93[49]
8 DDAH1 N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 [50] -1.21[51] -0.15[52] -0.31[53] -1.39[54] -0.75[55] 1.45[56]
9 DNM2 Dynamin-2 [57] 2.41[58] 0.73[59] 1.57[60] 0.70[61] 1.37[62] 1.18[63]
10 WASL Neural Wiskott-Aldrich syndrome protein [64] -0.08[65] 0.38[66] 1.35[67] 0.85[68] 0.41[69] 1.54[70]
11 DDAH2 N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 [71] -0.43[72] -0.12[73] 1.52[74] 0.91[75] -1.48[76] -0.21[77]
12 CYGB Cytoglobin [78] 4.59[79] 3.73[80] -1.31[81] -1.86[82] 1.18[83] -0.42[84]
13 ZDHHC21 Palmitoyltransferase ZDHHC21 [85] 2.27[86] 2.51[87] -2.13[88] 3.04[89] 2.89[90] 4.43[91]
14 NOS3 Nitric oxide synthase, endothelial [92] 5.17[93] 1.66[94] 1.70[95] -0.20[96] 1.54[97] 3.18[98]
15 NOSTRIN Nostrin [99] 0.38[100] -0.85[101] 2.88[102] 1.38[103] -0.28[104] 4.10[105]
[1]
ref_hepatocyte HSP90AA1
Mean 356
Standard deviation 2.5e+02
Values 5.4e+02 6.9e+02 1.3e+02 2.5e+02 1.7e+02
[2]
HepG2 HSP90AA1
Mean 503
Standard deviation 2.6e+02
Values 3.2e+02 6.9e+02
[3]
HepG2.C3A HSP90AA1
Mean 878
Standard deviation 5.2e+02
Values 5.1e+02 1.2e+03
[4]
HuH.7 HSP90AA1
Mean 494
Standard deviation 76
Values 5.4e+02 4.1e+02 5.4e+02
[5]
SNU475 HSP90AA1
Mean 696
Standard deviation 1.5e+02
Values 5.9e+02 8e+02
[6]
THLE HSP90AA1
Mean 627
Standard deviation 16
Values 6.4e+02 6.2e+02
[7]
liver HSP90AA1
Mean 212
Standard deviation 50
Values 2.7e+02 1.9e+02 2.4e+02 1.6e+02
[8]
ref_hepatocyte AKT1
Mean 37.6
Standard deviation 15
Values 55 50 19 31 32
[9]
HepG2 AKT1
Mean 87.8
Standard deviation 2.3
Values 89 86
[10]
HepG2.C3A AKT1
Mean 66.6
Standard deviation 2.4
Values 65 68
[11]
HuH.7 AKT1
Mean 30.2
Standard deviation 6.6
Values 33 23 35
[12]
SNU475 AKT1
Mean 66.6
Standard deviation 14
Values 76 57
[13]
THLE AKT1
Mean 75.8
Standard deviation 6.1
Values 72 80
[14]
liver AKT1
Mean 45.1
Standard deviation 25
Values 34 48 20 79
[15]
ref_hepatocyte SPR
Mean 32.1
Standard deviation 17
Values 11 25 26 54 44
[16]
HepG2 SPR
Mean 27.6
Standard deviation 12
Values 19 36
[17]
HepG2.C3A SPR
Mean 40.1
Standard deviation 7.9
Values 35 46
[18]
HuH.7 SPR
Mean 13.4
Standard deviation 3.9
Values 13 9.4 17
[19]
SNU475 SPR
Mean 14.2
Standard deviation 2.4
Values 16 12
[20]
THLE SPR
Mean 8.29
Standard deviation 1.3
Values 7.4 9.2
[21]
liver SPR
Mean 25.9
Standard deviation 13
Values 40 15 34 15
[22]
ref_hepatocyte CALM1
Mean 29.2
Standard deviation 11
Values 17 40 21 28 40
[23]
HepG2 CALM1
Mean 67.9
Standard deviation 4.3
Values 65 71
[24]
HepG2.C3A CALM1
Mean 62
Standard deviation 16
Values 51 73
[25]
HuH.7 CALM1
Mean 81.9
Standard deviation 15
Values 90 64 92
[26]
SNU475 CALM1
Mean 160
Standard deviation 24
Values 1.8e+02 1.4e+02
[27]
THLE CALM1
Mean 109
Standard deviation 13
Values 1e+02 1.2e+02
[28]
liver CALM1
Mean 127
Standard deviation 70
Values 2.1e+02 80 1.7e+02 57
[29]
ref_hepatocyte CAV1
Mean 22.6
Standard deviation 36
Values 0 84 28 0.35 0.99
[30]
HepG2 CAV1
Mean 0.438
Standard deviation 0.44
Values 0.75 0.12
[31]
HepG2.C3A CAV1
Mean 0.055
Standard deviation 0.032
Values 0.078 0.032
[32]
HuH.7 CAV1
Mean 4.08
Standard deviation 1.9
Values 3.5 6.2 2.5
[33]
SNU475 CAV1
Mean 108
Standard deviation 15
Values 1.2e+02 98
[34]
THLE CAV1
Mean 47.4
Standard deviation 15
Values 37 58
[35]
liver CAV1
Mean 8.05
Standard deviation 2.9
Values 7.6 8.2 12 4.7
[36]
ref_hepatocyte NOSIP
Mean 18.5
Standard deviation 9
Values 6.7 12 28 25 21
[37]
HepG2 NOSIP
Mean 21.4
Standard deviation 0.79
Values 22 21
[38]
HepG2.C3A NOSIP
Mean 23.5
Standard deviation 3.1
Values 21 26
[39]
HuH.7 NOSIP
Mean 29.2
Standard deviation 6.9
Values 30 22 36
[40]
SNU475 NOSIP
Mean 17.4
Standard deviation 3.7
Values 15 20
[41]
THLE NOSIP
Mean 20.6
Standard deviation 0.37
Values 20 21
[42]
liver NOSIP
Mean 10.6
Standard deviation 8.2
Values 19 4 16 3.3
[43]
ref_hepatocyte LYPLA1
Mean 18.3
Standard deviation 8
Values 19 28 15 7.1 23
[44]
HepG2 LYPLA1
Mean 42.9
Standard deviation 0.83
Values 42 43
[45]
HepG2.C3A LYPLA1
Mean 60.6
Standard deviation 8.8
Values 54 67
[46]
HuH.7 LYPLA1
Mean 30.3
Standard deviation 5.1
Values 34 25 32
[47]
SNU475 LYPLA1
Mean 37.5
Standard deviation 6.3
Values 42 33
[48]
THLE LYPLA1
Mean 37.7
Standard deviation 6.8
Values 33 43
[49]
liver LYPLA1
Mean 37.3
Standard deviation 14
Values 46 29 52 22
[50]
ref_hepatocyte DDAH1
Mean 18.2
Standard deviation 7.2
Values 17 22 8.7 15 28
[51]
HepG2 DDAH1
Mean 13.1
Standard deviation 6.7
Values 8.3 18
[52]
HepG2.C3A DDAH1
Mean 37.3
Standard deviation 0.88
Values 37 38
[53]
HuH.7 DDAH1
Mean 21.5
Standard deviation 5.4
Values 26 16 22
[54]
SNU475 DDAH1
Mean 15.3
Standard deviation 2
Values 17 14
[55]
THLE DDAH1
Mean 20.1
Standard deviation 1.4
Values 21 19
[56]
liver DDAH1
Mean 53.2
Standard deviation 26
Values 80 35 70 28
[57]
ref_hepatocyte DNM2
Mean 12.4
Standard deviation 3.9
Values 7.7 11 17 16 11
[58]
HepG2 DNM2
Mean 111
Standard deviation 21
Values 1.3e+02 96
[59]
HepG2.C3A DNM2
Mean 47.1
Standard deviation 1.8
Values 48 46
[60]
HuH.7 DNM2
Mean 54.4
Standard deviation 4.5
Values 59 53 51
[61]
SNU475 DNM2
Mean 44.3
Standard deviation 3.3
Values 47 42
[62]
THLE DNM2
Mean 59.7
Standard deviation 7.8
Values 54 65
[63]
liver DNM2
Mean 30.1
Standard deviation 7.9
Values 23 30 26 41
[64]
ref_hepatocyte WASL
Mean 8.59
Standard deviation 2.4
Values 12 10 6.2 6.4 8.7
[65]
HepG2 WASL
Mean 13.6
Standard deviation 3.9
Values 11 16
[66]
HepG2.C3A WASL
Mean 25.4
Standard deviation 2.9
Values 28 23
[67]
HuH.7 WASL
Mean 32.2
Standard deviation 9.3
Values 28 43 25
[68]
SNU475 WASL
Mean 33.9
Standard deviation 2.2
Values 35 32
[69]
THLE WASL
Mean 21.2
Standard deviation 0.65
Values 21 22
[70]
liver WASL
Mean 26.7
Standard deviation 9.5
Values 39 19 30 19
[71]
ref_hepatocyte DDAH2
Mean 7.13
Standard deviation 6.5
Values 1.1 1.7 4.9 16 12
[72]
HepG2 DDAH2
Mean 8.85
Standard deviation 1.5
Values 9.9 7.8
[73]
HepG2.C3A DDAH2
Mean 14.9
Standard deviation 3.8
Values 18 12
[74]
HuH.7 DDAH2
Mean 30.1
Standard deviation 6.7
Values 32 23 36
[75]
SNU475 DDAH2
Mean 29.4
Standard deviation 7.1
Values 34 24
[76]
THLE DDAH2
Mean 4.75
Standard deviation 0.76
Values 4.2 5.3
[77]
liver DDAH2
Mean 6.58
Standard deviation 3.6
Values 12 3.1 5.8 5.7
[78]
ref_hepatocyte CYGB
Mean 0.536
Standard deviation 0.24
Values 0.33 0.33 0.86 0.46 0.71
[79]
HepG2 CYGB
Mean 21.6
Standard deviation 7.1
Values 27 17
[80]
HepG2.C3A CYGB
Mean 16.2
Standard deviation 0.39
Values 16 16
[81]
HuH.7 CYGB
Mean 0.317
Standard deviation 0.013
Values 0.32 0.3 0.33
[82]
SNU475 CYGB
Mean 0.324
Standard deviation 0.13
Values 0.23 0.42
[83]
THLE CYGB
Mean 2.26
Standard deviation 0.58
Values 2.7 1.8
[84]
liver CYGB
Mean 0.428
Standard deviation 0.26
Values 0.73 0.17 0.26 0.56
[85]
ref_hepatocyte ZDHHC21
Mean 0.524
Standard deviation 0.13
Values 0.67 0.6 0.54 0.32 0.5
[86]
HepG2 ZDHHC21
Mean 4.21
Standard deviation 2.1
Values 2.7 5.7
[87]
HepG2.C3A ZDHHC21
Mean 6.79
Standard deviation 1.4
Values 5.8 7.8
[88]
HuH.7 ZDHHC21
Mean 0.176
Standard deviation 0.13
Values 0.12 0.32 0.084
[89]
SNU475 ZDHHC21
Mean 9.43
Standard deviation 1.3
Values 10 8.5
[90]
THLE ZDHHC21
Mean 7.2
Standard deviation 0.98
Values 7.9 6.5
[91]
liver ZDHHC21
Mean 12.1
Standard deviation 5.7
Values 7.8 20 8.6 12
[92]
ref_hepatocyte NOS3
Mean 0.251
Standard deviation 0.22
Values 0.58 0.37 0.014 0.12 0.18
[93]
HepG2 NOS3
Mean 15.1
Standard deviation 1.3
Values 14 16
[94]
HepG2.C3A NOS3
Mean 1.81
Standard deviation 0.061
Values 1.8 1.9
[95]
HuH.7 NOS3
Mean 1.2
Standard deviation 0.2
Values 1.4 1 1.2
[96]
SNU475 NOS3
Mean 0.48
Standard deviation 0.28
Values 0.68 0.28
[97]
THLE NOS3
Mean 1.36
Standard deviation 0.21
Values 1.5 1.2
[98]
liver NOS3
Mean 2.44
Standard deviation 1.3
Values 1.5 2.3 1.6 4.3
[99]
ref_hepatocyte NOSTRIN
Mean 0.23
Standard deviation 0.22
Values 0.064 0.56 0 0.3 0.22
[100]
HepG2 NOSTRIN
Mean 0.5
Standard deviation 0.12
Values 0.41 0.59
[101]
HepG2.C3A NOSTRIN
Mean 0.289
Standard deviation 0.26
Values 0.11 0.47
[102]
HuH.7 NOSTRIN
Mean 2.49
Standard deviation 0.092
Values 2.5 2.4 2.5
[103]
SNU475 NOSTRIN
Mean 1.31
Standard deviation 0.34
Values 1.6 1.1
[104]
THLE NOSTRIN
Mean 0.352
Standard deviation 0.046
Values 0.38 0.32
[105]
liver NOSTRIN
Mean 4.21
Standard deviation 0.83
Values 4.6 3.8 5.2 3.3