REACTOME_METABOLISM_OF_FAT_SOLUBLE_VITAMINS | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | APOA2 | Apolipoprotein A-II | [1] | -1.06[2] | -0.60[3] | -0.75[4] | -9.06[5] | -7.01[6] | -1.11[7] |
2 | APOA1 | Apolipoprotein A-I | [8] | -1.04[9] | -0.35[10] | -2.11[11] | -9.57[12] | -7.91[13] | -0.13[14] |
3 | APOC3 | Apolipoprotein C-III | [15] | -4.90[16] | -2.81[17] | -3.55[18] | -12.19[19] | -10.99[20] | -0.63[21] |
4 | RBP4 | Retinol-binding protein 4 | [22] | -2.37[23] | -1.77[24] | -0.18[25] | -8.45[26] | -6.12[27] | -0.11[28] |
5 | APOE | Apolipoprotein E | [29] | -0.45[30] | -0.67[31] | 0.17[32] | -6.29[33] | -3.71[34] | -0.82[35] |
6 | TTR | Transthyretin | [36] | -3.91[37] | -2.19[38] | -2.45[39] | -11.21[40] | -9.10[41] | -1.37[42] |
7 | APOC2 | Apolipoprotein C-II | [43] | [44] | [45] | [46] | [47] | [48] | [49] |
8 | AKR1C1 | Aldo-keto reductase family 1 member C1 | [50] | 0.45[51] | -0.47[52] | -3.31[53] | 1.63[54] | -1.34[55] | -3.22[56] |
9 | AKR1C3 | Aldo-keto reductase family 1 member C3 | [57] | 0.93[58] | 0.96[59] | -4.81[60] | 4.87[61] | -0.38[62] | -1.17[63] |
10 | APOB | Apolipoprotein B-100 | [64] | 5.14[65] | 5.32[66] | 5.37[67] | -2.95[68] | -1.08[69] | 5.88[70] |
11 | APOM | Apolipoprotein M | [71] | -1.51[72] | 1.97[73] | 0.25[74] | -4.02[75] | -3.06[76] | -0.13[77] |
12 | VKORC1 | Vitamin K epoxide reductase complex subunit 1 | [78] | 1.56[79] | 0.96[80] | 1.00[81] | 0.82[82] | 3.21[83] | 0.11[84] |
13 | GPC3 | Glypican-3 | [85] | 5.38[86] | 5.21[87] | 4.72[88] | -3.41[89] | -1.39[90] | -7.21[91] |
14 | AKR1C4 | Aldo-keto reductase family 1 member C4 | [92] | -5.86[93] | -4.10[94] | -3.81[95] | -6.18[96] | -9.85[97] | 0.14[98] |
15 | SDC1 | Syndecan-1 | [99] | 2.71[100] | 1.65[101] | 2.87[102] | 2.13[103] | 1.64[104] | 1.80[105] |
16 | SDC4 | Syndecan-4 | [106] | 3.51[107] | 2.59[108] | 2.23[109] | 2.73[110] | 6.10[111] | 0.91[112] |
17 | AKR1B10 | Aldo-keto reductase family 1 member B10 | [113] | 2.30[114] | 0.68[115] | -3.56[116] | 7.27[117] | -0.75[118] | -2.90[119] |
18 | RDH11 | Retinol dehydrogenase 11 | [120] | 1.08[121] | 1.99[122] | 2.84[123] | 2.81[124] | 4.71[125] | 1.52[126] |
19 | SDC2 | Syndecan-2 | [127] | 3.61[128] | 3.96[129] | 4.47[130] | 4.30[131] | 2.90[132] | 1.64[133] |
20 | APOA4 | Apolipoprotein A-IV | [134] | 0.55[135] | 1.71[136] | -3.42[137] | -8.19[138] | -7.81[139] | 2.31[140] |
21 | RETSAT | All-trans-retinol 13,14-reductase | [141] | 3.04[142] | 3.09[143] | 2.81[144] | 3.61[145] | 4.84[146] | 1.45[147] |
22 | LDLR | Low-density lipoprotein receptor | [148] | 3.39[149] | 3.64[150] | 5.51[151] | 3.59[152] | 6.60[153] | 2.25[154] |
23 | LRP10 | Low-density lipoprotein receptor-related protein 10 | [155] | 4.59[156] | 1.58[157] | 4.41[158] | 5.60[159] | 7.58[160] | 1.66[161] |
24 | LRP1 | Prolow-density lipoprotein receptor-related protein 1 | [162] | 7.03[163] | 4.73[164] | 6.58[165] | 6.84[166] | 8.63[167] | 6.16[168] |
25 | TTPA | Alpha-tocopherol transfer protein | [169] | 0.20[170] | -3.96[171] | -0.20[172] | -4.50[173] | -1.93[174] | 2.92[175] |
26 | GPC1 | Glypican-1 | [176] | 3.70[177] | -0.23[178] | -3.37[179] | 6.94[180] | 7.54[181] | 0.49[182] |
27 | VKORC1L1 | Vitamin K epoxide reductase complex subunit 1-like protein 1 | [183] | 1.78[184] | 1.14[185] | 2.54[186] | 3.33[187] | 4.96[188] | -0.47[189] |
28 | BCO2 | Beta,beta-carotene 9',10'-oxygenase | [190] | -1.26[191] | -0.56[192] | -0.94[193] | 0.77[194] | 3.74[195] | 2.54[196] |
29 | AGRN | Agrin | [197] | 7.36[198] | 6.19[199] | 6.55[200] | 8.02[201] | 8.88[202] | 2.09[203] |
30 | UBIAD1 | UbiA prenyltransferase domain-containing protein 1 | [204] | 4.04[205] | 4.01[206] | 3.58[207] | 3.71[208] | 6.10[209] | 1.29[210] |
31 | RBP1 | Retinol-binding protein 1 | [211] | 5.34[212] | 0.04[213] | 2.18[214] | 3.31[215] | 1.31[216] | 1.87[217] |
32 | RBP2 | Retinol-binding protein 2 | [218] | -2.04[219] | 0.27[220] | 7.10[221] | -1.33[222] | 0.35[223] | -7.11[224] |
33 | GPC6 | Glypican-6 | [225] | 5.81[226] | 4.39[227] | 5.85[228] | 8.43[229] | 8.33[230] | 4.28[231] |
34 | SDC3 | Syndecan-3 | [232] | 6.00[233] | -0.82[234] | 4.06[235] | 7.61[236] | 9.71[237] | 3.77[238] |
35 | LRP8 | Low-density lipoprotein receptor-related protein 8 | [239] | 5.63[240] | 5.80[241] | 7.04[242] | 7.99[243] | 9.74[244] | -1.02[245] |
36 | HSPG2 | Basement membrane-specific heparan sulfate proteoglycan core protein | 10.82[246] | 8.46[247] | 9.72[248] | 10.53[249] | 12.51[250] | 7.39[251] | |
37 | GPC4 | Glypican-4 | [252] | 2.19[253] | -2.46[254] | 2.19[255] | 9.96[256] | 4.01[257] | 1.96[258] |
38 | LRP12 | Low-density lipoprotein receptor-related protein 12 | [259] | 5.42[260] | 1.90[261] | 6.11[262] | 10.43[263] | 11.60[264] | 2.91[265] |
39 | LPL | Lipoprotein lipase | [266] | [267] | [268] | -3.93[269] | 5.06[270] | 3.24[271] | 0.78[272] |
40 | LRAT | Lecithin retinol acyltransferase | [273] | 1.50[274] | 1.48[275] | 1.13[276] | 3.05[277] | 5.47[278] | 6.22[279] |
41 | LRP2 | Low-density lipoprotein receptor-related protein 2 | [280] | 5.51[281] | 1.58[282] | 11.13[283] | 2.21[284] | 3.76[285] | 7.24[286] |
42 | GPC5 | Glypican-5 | [287] | 0.01[288] | -1.90[289] | 3.35[290] | 1.25[291] | 3.57[292] | 4.59[293] |
43 | GPC2 | Glypican-2 | [294] | 6.11[295] | 4.95[296] | 7.84[297] | 7.83[298] | 8.48[299] | -2.05[300] |
44 | PLB1 | Phospholipase B1, membrane-associated | [301] | 7.72[302] | 1.85[303] | 3.98[304] | 8.06[305] | 7.63[306] | 4.20[307] |
45 | CLPS | Colipase | [308] | [309] | [310] | [311] | [312] | 2.22[313] | 0.17[314] |
46 | GPIHBP1 | Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 | [315] | 0.32[316] | [317] | 1.23[318] | 3.08[319] | 6.18[320] | |
47 | PNLIP | Pancreatic triacylglycerol lipase | [321] | [322] | [323] | [324] | [325] | [326] | [327] |
48 | BCO1 | Beta,beta-carotene 15,15'-dioxygenase | [328] | [329] | [330] | [331] | [332] | [333] | [334] |