REACTOME_METABOLIC_DISORDERS_OF_BIOLOGICAL_OXIDATION_ENZYMES Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 MAT1A S-adenosylmethionine synthase isoform type-1 [1] -2.49[2] -0.67[3] -2.19[4] -8.38[5] -10.60[6] 0.71[7]
2 CYP27A1 Sterol 26-hydroxylase, mitochondrial [8] -1.06[9] -0.33[10] -3.02[11] -2.50[12] -3.76[13] -0.14[14]
3 FMO3 Dimethylaniline monooxygenase [N-oxide-forming] 3 [15] [16] -14.57[17] -7.32[18] -6.72[19] -13.25[20] -1.33[21]
4 ACY1 Aminoacylase-1 [22] -5.01[23] -4.38[24] -3.40[25] -6.57[26] -5.80[27] -5.45[28]
5 AHCY Adenosylhomocysteinase [29] 2.01[30] 2.38[31] 3.01[32] 1.28[33] 1.15[34] -1.24[35]
6 UGT1A1 UDP-glucuronosyltransferase 1-1 [36] -5.34[37] -11.66[38] -6.10[39] -0.29[40] -9.99[41] -0.27[42]
7 UGT1A4 UDP-glucuronosyltransferase 1-4 [43] -12.72[44] [45] -12.00[46] -9.56[47] [48] -0.09[49]
8 GCLC Glutamate--cysteine ligase catalytic subunit [50] 0.67[51] 0.97[52] 0.15[53] 3.01[54] 0.59[55] 0.19[56]
9 TPMT Thiopurine S-methyltransferase [57] -0.60[58] 0.12[59] -0.96[60] 0.66[61] 0.56[62] -0.37[63]
10 MAOA Amine oxidase [flavin-containing] A [64] -2.17[65] -1.45[66] 1.21[67] -2.59[68] 2.90[69] 1.28[70]
11 GCLM Glutamate--cysteine ligase regulatory subunit [71] 0.05[72] -0.78[73] 0.09[74] 2.90[75] 1.38[76] -1.06[77]
12 GSS Glutathione synthetase [78] 1.72[79] 1.37[80] 1.11[81] 2.38[82] 2.08[83] -0.47[84]
13 GGT1 Glutathione hydrolase 1 proenzyme [85] 0.35[86] 0.02[87] 0.19[88] -0.13[89] -4.37[90] 0.49[91]
14 FDX1 Adrenodoxin, mitochondrial [92] 0.33[93] -0.18[94] -1.30[95] 1.76[96] 1.98[97] 0.58[98]
15 SLC35D1 UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter [99] 1.69[100] 1.95[101] 2.54[102] 1.21[103] 2.13[104] 2.74[105]
16 FDXR NADPH:adrenodoxin oxidoreductase, mitochondrial [106] 3.63[107] 2.89[108] 0.15[109] 0.16[110] 1.54[111] -2.14[112]
17 CYP21A2 Steroid 21-hydroxylase [113] -4.84[114] -2.97[115] -6.95[116] -2.18[117] -7.18[118] -0.50[119]
18 OPLAH 5-oxoprolinase [120] 1.96[121] 1.95[122] 0.82[123] 1.64[124] -0.11[125] 1.45[126]
19 CYP2R1 Vitamin D 25-hydroxylase [127] -2.96[128] -1.23[129] 1.39[130] 0.73[131] 0.52[132] -1.10[133]
20 CYP4F22 Cytochrome P450 4F22 [134] -4.85[135] [136] -9.53[137] -7.90[138] -5.80[139] -1.20[140]
21 CYP1B1 Cytochrome P450 1B1 [141] -6.02[142] -5.52[143] -1.02[144] 3.56[145] 6.47[146] 0.79[147]
22 CYP7B1 25-hydroxycholesterol 7-alpha-hydroxylase [148] -7.01[149] -5.79[150] [151] -6.97[152] -2.94[153] 2.04[154]
23 CYP19A1 Aromatase [155] 2.95[156] 3.91[157] -2.14[158] 0.40[159] -1.75[160] -6.56[161]
24 CYP2U1 Cytochrome P450 2U1 [162] 1.20[163] -2.67[164] -2.07[165] 3.29[166] 4.38[167] 1.85[168]
25 TBXAS1 Thromboxane-A synthase [169] -1.95[170] 0.05[171] -2.74[172] 2.70[173] 1.55[174] 1.42[175]
26 CYP11A1 Cholesterol side-chain cleavage enzyme, mitochondrial [176] 0.37[177] -2.21[178] [179] -1.21[180] 3.15[181] 0.24[182]
27 CYP24A1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial [183] 9.17[184] 4.24[185] -1.01[186] 6.16[187] -0.34[188] -7.32[189]
28 CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase [190] -1.72[191] 2.27[192] -0.77[193] -3.68[194] -3.34[195] 1.42[196]
29 CYP27B1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial [197] 3.70[198] 5.08[199] 4.87[200] 3.24[201] 4.28[202] 1.44[203]
30 CYP26B1 Cytochrome P450 26B1 [204] 5.91[205] 2.80[206] 10.41[207] 8.76[208] 8.29[209] 5.31[210]
31 CYP11B1 Cytochrome P450 11B1, mitochondrial [211] [212] [213] [214] [215] [216] [217]
32 CYP11B2 Cytochrome P450 11B2, mitochondrial [218] [219] [220] [221] [222] [223] [224]
33 FDX2 Ferredoxin-2, mitochondrial [225] [226] [227] [228] [229] [230] [231]
34 CYP26C1 Cytochrome P450 26C1 [232] [233] [234] [235] [236] [237] [238]
[1]
ref_hepatocyte MAT1A
Mean 212
Standard deviation 2.8e+02
Values 46 12 7.2 3.6e+02 6.3e+02
[2]
HepG2 MAT1A
Mean 41.1
Standard deviation 3.9
Values 38 44
[3]
HepG2.C3A MAT1A
Mean 135
Standard deviation 10
Values 1.4e+02 1.3e+02
[4]
HuH.7 MAT1A
Mean 34.1
Standard deviation 22
Values 20 60 22
[5]
SNU475 MAT1A
Mean 0.281
Standard deviation 0.061
Values 0.32 0.24
[6]
THLE MAT1A
Mean 0.055
Standard deviation 0.048
Values 0.089 0.021
[7]
liver MAT1A
Mean 578
Standard deviation 1.7e+02
Values 4.8e+02 6.1e+02 8.1e+02 4.1e+02
[8]
ref_hepatocyte CYP27A1
Mean 135
Standard deviation 1.6e+02
Values 62 8 18 2.1e+02 3.7e+02
[9]
HepG2 CYP27A1
Mean 70.5
Standard deviation 16
Values 59 82
[10]
HepG2.C3A CYP27A1
Mean 108
Standard deviation 25
Values 1.3e+02 90
[11]
HuH.7 CYP27A1
Mean 12.2
Standard deviation 7.3
Values 7.2 21 8.9
[12]
SNU475 CYP27A1
Mean 10.5
Standard deviation 1.6
Values 12 9.4
[13]
THLE CYP27A1
Mean 4.01
Standard deviation 0.91
Values 4.7 3.4
[14]
liver CYP27A1
Mean 204
Standard deviation 1e+02
Values 3.3e+02 1.2e+02 2.5e+02 1.1e+02
[15]
ref_hepatocyte FMO3
Mean 129
Standard deviation 2.2e+02
Values 0 3.5 4.9 1.2e+02 5.1e+02
[16]
HepG2 FMO3
Mean 0
Standard deviation 0
Values 0 0
[17]
HepG2.C3A FMO3
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[18]
HuH.7 FMO3
Mean 0.593
Standard deviation 0.31
Values 0.36 0.95 0.47
[19]
SNU475 FMO3
Mean 0.542
Standard deviation 0.086
Values 0.6 0.48
[20]
THLE FMO3
Mean 0.00532
Standard deviation 0.0075
Values 0 0.011
[21]
liver FMO3
Mean 85.3
Standard deviation 26
Values 1.2e+02 64 75 80
[22]
ref_hepatocyte ACY1
Mean 72.1
Standard deviation 60
Values 21 45 22 1.2e+02 1.5e+02
[23]
HepG2 ACY1
Mean 2.42
Standard deviation 0.67
Values 2.9 2
[24]
HepG2.C3A ACY1
Mean 3.49
Standard deviation 0.8
Values 2.9 4.1
[25]
HuH.7 ACY1
Mean 5.02
Standard deviation 1.4
Values 6.3 3.5 5.3
[26]
SNU475 ACY1
Mean 0.334
Standard deviation 0.16
Values 0.45 0.22
[27]
THLE ACY1
Mean 0.518
Standard deviation 0.013
Values 0.51 0.53
[28]
liver ACY1
Mean 2.74
Standard deviation 2.8
Values 5.1 0.36 5.2 0.26
[29]
ref_hepatocyte AHCY
Mean 72
Standard deviation 24
Values 1e+02 71 38 80 67
[30]
HepG2 AHCY
Mean 316
Standard deviation 75
Values 3.7e+02 2.6e+02
[31]
HepG2.C3A AHCY
Mean 377
Standard deviation 69
Values 4.3e+02 3.3e+02
[32]
HuH.7 AHCY
Mean 425
Standard deviation 39
Values 4.7e+02 4e+02 4e+02
[33]
SNU475 AHCY
Mean 77.3
Standard deviation 9.8
Values 84 70
[34]
THLE AHCY
Mean 64.2
Standard deviation 8.6
Values 58 70
[35]
liver AHCY
Mean 50.8
Standard deviation 11
Values 55 45 64 40
[36]
ref_hepatocyte UGT1A1
Mean 67.2
Standard deviation 89
Values 0.52 12 15 2.1e+02 96
[37]
HepG2 UGT1A1
Mean 1.8
Standard deviation 0.2
Values 1.9 1.7
[38]
HepG2.C3A UGT1A1
Mean 0.0209
Standard deviation 0.016
Values 0.0097 0.032
[39]
HuH.7 UGT1A1
Mean 0.72
Standard deviation 0.5
Values 0.57 1.3 0.31
[40]
SNU475 UGT1A1
Mean 24.4
Standard deviation 21
Values 39 9.8
[41]
THLE UGT1A1
Mean 0.0266
Standard deviation 0.038
Values 0 0.053
[42]
liver UGT1A1
Mean 92.4
Standard deviation 46
Values 1.1e+02 83 1.4e+02 34
[43]
ref_hepatocyte UGT1A4
Mean 53.1
Standard deviation 73
Values 0 4.2 2.5 99 1.6e+02
[44]
HepG2 UGT1A4
Mean 0.00858
Standard deviation 0.012
Values 0 0.017
[45]
HepG2.C3A UGT1A4
Mean 0
Standard deviation 0
Values 0 0
[46]
HuH.7 UGT1A4
Mean 0.00954
Standard deviation 0.0096
Values 0 0.019 0.0094
[47]
SNU475 UGT1A4
Mean 0.031
Standard deviation 0.015
Values 0.042 0.02
[48]
THLE UGT1A4
Mean 0
Standard deviation 0
Values 0 0
[49]
liver UGT1A4
Mean 83.1
Standard deviation 65
Values 36 95 1.7e+02 32
[50]
ref_hepatocyte GCLC
Mean 23.9
Standard deviation 11
Values 14 17 36 16 37
[51]
HepG2 GCLC
Mean 41.2
Standard deviation 0.21
Values 41 41
[52]
HepG2.C3A GCLC
Mean 47.1
Standard deviation 0.68
Values 48 47
[53]
HuH.7 GCLC
Mean 19.4
Standard deviation 7.4
Values 15 28 15
[54]
SNU475 GCLC
Mean 84.8
Standard deviation 9.1
Values 91 78
[55]
THLE GCLC
Mean 14.4
Standard deviation 0.55
Values 15 14
[56]
liver GCLC
Mean 45.3
Standard deviation 20
Values 37 59 22 64
[57]
ref_hepatocyte TPMT
Mean 23.4
Standard deviation 7.6
Values 18 24 32 14 29
[58]
HepG2 TPMT
Mean 16.8
Standard deviation 5.6
Values 13 21
[59]
HepG2.C3A TPMT
Mean 25.6
Standard deviation 12
Values 17 34
[60]
HuH.7 TPMT
Mean 8.85
Standard deviation 2.1
Values 9.3 6.6 11
[61]
SNU475 TPMT
Mean 16.4
Standard deviation 0.91
Values 17 16
[62]
THLE TPMT
Mean 13.9
Standard deviation 0.98
Values 13 15
[63]
liver TPMT
Mean 30.1
Standard deviation 12
Values 40 22 42 18
[64]
ref_hepatocyte MAOA
Mean 22.1
Standard deviation 16
Values 3.4 23 8.6 34 41
[65]
HepG2 MAOA
Mean 5.32
Standard deviation 0.22
Values 5.5 5.2
[66]
HepG2.C3A MAOA
Mean 8.16
Standard deviation 2.3
Values 9.8 6.5
[67]
HuH.7 MAOA
Mean 37.5
Standard deviation 10
Values 36 49 28
[68]
SNU475 MAOA
Mean 1.62
Standard deviation 0.75
Values 1.1 2.1
[69]
THLE MAOA
Mean 66.1
Standard deviation 1.4
Values 67 65
[70]
liver MAOA
Mean 88.9
Standard deviation 19
Values 1.1e+02 90 88 65
[71]
ref_hepatocyte GCLM
Mean 20.7
Standard deviation 17
Values 12 45 32 8.4 5.2
[72]
HepG2 GCLM
Mean 23.3
Standard deviation 15
Values 34 13
[73]
HepG2.C3A GCLM
Mean 12.1
Standard deviation 3.1
Values 9.9 14
[74]
HuH.7 GCLM
Mean 16.1
Standard deviation 2.7
Values 16 19 13
[75]
SNU475 GCLM
Mean 68.3
Standard deviation 0.053
Values 68 68
[76]
THLE GCLM
Mean 21.6
Standard deviation 2.7
Values 20 24
[77]
liver GCLM
Mean 16.4
Standard deviation 8.1
Values 18 14 27 7
[78]
ref_hepatocyte GSS
Mean 17.2
Standard deviation 2.6
Values 14 16 20 20 17
[79]
HepG2 GSS
Mean 61.8
Standard deviation 7.1
Values 57 67
[80]
HepG2.C3A GSS
Mean 45
Standard deviation 7.3
Values 40 50
[81]
HuH.7 GSS
Mean 27.4
Standard deviation 7
Values 27 20 34
[82]
SNU475 GSS
Mean 39.8
Standard deviation 5.9
Values 44 36
[83]
THLE GSS
Mean 29.3
Standard deviation 2.5
Values 27 31
[84]
liver GSS
Mean 20.8
Standard deviation 9.9
Values 26 14 32 11
[85]
ref_hepatocyte GGT1
Mean 15.1
Standard deviation 12
Values 0.7 20 4.1 29 22
[86]
HepG2 GGT1
Mean 20.9
Standard deviation 6.9
Values 26 16
[87]
HepG2.C3A GGT1
Mean 15.5
Standard deviation 4.3
Values 19 12
[88]
HuH.7 GGT1
Mean 12.7
Standard deviation 3.6
Values 11 17 9.9
[89]
SNU475 GGT1
Mean 6.1
Standard deviation 1.7
Values 7.3 4.9
[90]
THLE GGT1
Mean 0.294
Standard deviation 0.0057
Values 0.29 0.3
[91]
liver GGT1
Mean 35.2
Standard deviation 23
Values 65 15 40 21
[92]
ref_hepatocyte FDX1
Mean 11.4
Standard deviation 6.1
Values 10 11 2.2 14 19
[93]
HepG2 FDX1
Mean 15.5
Standard deviation 0.65
Values 15 16
[94]
HepG2.C3A FDX1
Mean 10.2
Standard deviation 2.3
Values 8.6 12
[95]
HuH.7 FDX1
Mean 3.41
Standard deviation 0.095
Values 3.3 3.4 3.5
[96]
SNU475 FDX1
Mean 17.1
Standard deviation 1.7
Values 18 16
[97]
THLE FDX1
Mean 18.1
Standard deviation 3.7
Values 15 21
[98]
liver FDX1
Mean 28.4
Standard deviation 18
Values 44 15 44 12
[99]
ref_hepatocyte SLC35D1
Mean 8.48
Standard deviation 5.2
Values 14 5.1 2.5 6.8 14
[100]
HepG2 SLC35D1
Mean 29.7
Standard deviation 14
Values 20 40
[101]
HepG2.C3A SLC35D1
Mean 33
Standard deviation 8.8
Values 27 39
[102]
HuH.7 SLC35D1
Mean 36.2
Standard deviation 6.9
Values 44 30 35
[103]
SNU475 SLC35D1
Mean 8.66
Standard deviation 1.5
Values 9.7 7.6
[104]
THLE SLC35D1
Mean 14.9
Standard deviation 3.7
Values 12 17
[105]
liver SLC35D1
Mean 93.9
Standard deviation 31
Values 69 1e+02 69 1.3e+02
[106]
ref_hepatocyte FDXR
Mean 7.28
Standard deviation 6.2
Values 18 3.2 2.7 8.3 4.5
[107]
HepG2 FDXR
Mean 97.8
Standard deviation 8.7
Values 92 1e+02
[108]
HepG2.C3A FDXR
Mean 54.6
Standard deviation 14
Values 45 64
[109]
HuH.7 FDXR
Mean 5.93
Standard deviation 2.4
Values 6.5 3.4 8
[110]
SNU475 FDXR
Mean 3.59
Standard deviation 0.45
Values 3.9 3.3
[111]
THLE FDXR
Mean 8.51
Standard deviation 1.3
Values 9.4 7.6
[112]
liver FDXR
Mean 2.74
Standard deviation 1.3
Values 3.3 2 4.4 1.3
[113]
ref_hepatocyte CYP21A2
Mean 5.14
Standard deviation 5.5
Values 0.5 0.83 2.4 13 9.3
[114]
HepG2 CYP21A2
Mean 0.195
Standard deviation 0.0088
Values 0.19 0.2
[115]
HepG2.C3A CYP21A2
Mean 0.66
Standard deviation 0.51
Values 1 0.3
[116]
HuH.7 CYP21A2
Mean 0.0306
Standard deviation 0.027
Values 0 0.045 0.047
[117]
SNU475 CYP21A2
Mean 0.502
Standard deviation 0.11
Values 0.43 0.58
[118]
THLE CYP21A2
Mean 0.0142
Standard deviation 0.005
Values 0.018 0.011
[119]
liver CYP21A2
Mean 6.05
Standard deviation 3.4
Values 2 6 10 5.9
[120]
ref_hepatocyte OPLAH
Mean 4.64
Standard deviation 4.4
Values 2.4 0.7 1.9 7.2 11
[121]
HepG2 OPLAH
Mean 19.7
Standard deviation 2.6
Values 22 18
[122]
HepG2.C3A OPLAH
Mean 18.1
Standard deviation 9.1
Values 25 12
[123]
HuH.7 OPLAH
Mean 6.03
Standard deviation 0.25
Values 6.2 5.7 6.2
[124]
SNU475 OPLAH
Mean 6.37
Standard deviation 3.8
Values 9.1 3.7
[125]
THLE OPLAH
Mean 1.73
Standard deviation 0.08
Values 1.7 1.8
[126]
liver OPLAH
Mean 21
Standard deviation 13
Values 14 19 10 40
[127]
ref_hepatocyte CYP2R1
Mean 2.89
Standard deviation 1.8
Values 0 4.7 3.6 3.9 2.3
[128]
HepG2 CYP2R1
Mean 0.405
Standard deviation 0.2
Values 0.54 0.27
[129]
HepG2.C3A CYP2R1
Mean 1.25
Standard deviation 0.41
Values 1.5 0.95
[130]
HuH.7 CYP2R1
Mean 5.56
Standard deviation 0.93
Values 4.6 5.8 6.4
[131]
SNU475 CYP2R1
Mean 2.12
Standard deviation 0.069
Values 2.2 2.1
[132]
THLE CYP2R1
Mean 1.67
Standard deviation 0.39
Values 1.9 1.4
[133]
liver CYP2R1
Mean 2.24
Standard deviation 0.78
Values 3.4 1.6 2 2
[134]
ref_hepatocyte CYP4F22
Mean 2.74
Standard deviation 3.4
Values 0 0.23 8.2 3.5 1.8
[135]
HepG2 CYP4F22
Mean 0.103
Standard deviation 0.15
Values 0.21 0
[136]
HepG2.C3A CYP4F22
Mean 0
Standard deviation 0
Values 0 0
[137]
HuH.7 CYP4F22
Mean 0.00273
Standard deviation 0.0047
Values 0.0082 0 0
[138]
SNU475 CYP4F22
Mean 0.00507
Standard deviation 0.0072
Values 0 0.01
[139]
THLE CYP4F22
Mean 0.0198
Standard deviation 0.0054
Values 0.024 0.016
[140]
liver CYP4F22
Mean 1.99
Standard deviation 1.8
Values 4.7 0.59 1.6 1.1
[141]
ref_hepatocyte CYP1B1
Mean 2.62
Standard deviation 3.2
Values 0.024 8 0.92 2.7 1.4
[142]
HepG2 CYP1B1
Mean 0.0437
Standard deviation 0.019
Values 0.057 0.03
[143]
HepG2.C3A CYP1B1
Mean 0.0575
Standard deviation 0.04
Values 0.029 0.086
[144]
HuH.7 CYP1B1
Mean 0.95
Standard deviation 0.082
Values 0.87 1 0.95
[145]
SNU475 CYP1B1
Mean 13.6
Standard deviation 3.1
Values 16 11
[146]
THLE CYP1B1
Mean 93
Standard deviation 14
Values 1e+02 83
[147]
liver CYP1B1
Mean 7.5
Standard deviation 1.4
Values 6.9 7.4 9.5 6.2
[148]
ref_hepatocyte CYP7B1
Mean 1.44
Standard deviation 1
Values 0 2.2 1.1 1.2 2.7
[149]
HepG2 CYP7B1
Mean 0.0122
Standard deviation 0.001
Values 0.011 0.013
[150]
HepG2.C3A CYP7B1
Mean 0.0263
Standard deviation 0.023
Values 0.0097 0.043
[151]
HuH.7 CYP7B1
Mean 0
Standard deviation 0
Values 0 0 0
[152]
SNU475 CYP7B1
Mean 0.00507
Standard deviation 0.0072
Values 0 0.01
[153]
THLE CYP7B1
Mean 0.0751
Standard deviation 0.014
Values 0.065 0.085
[154]
liver CYP7B1
Mean 9.87
Standard deviation 5.4
Values 6.3 17 4.8 12
[155]
ref_hepatocyte CYP19A1
Mean 1.13
Standard deviation 2.3
Values 5.3 0.08 0.28 0 0
[156]
HepG2 CYP19A1
Mean 9.51
Standard deviation 0.87
Values 8.9 10
[157]
HepG2.C3A CYP19A1
Mean 17.1
Standard deviation 5.6
Values 21 13
[158]
HuH.7 CYP19A1
Mean 0.188
Standard deviation 0.27
Values 0.016 0.5 0.047
[159]
SNU475 CYP19A1
Mean 0.66
Standard deviation 0.58
Values 0.25 1.1
[160]
THLE CYP19A1
Mean 0.135
Standard deviation 0.018
Values 0.15 0.12
[161]
liver CYP19A1
Mean 0.0199
Standard deviation 0.04
Values 0 0 0 0.079
[162]
ref_hepatocyte CYP2U1
Mean 1.09
Standard deviation 0.48
Values 0.81 1.1 0.46 1.4 1.7
[163]
HepG2 CYP2U1
Mean 2.73
Standard deviation 0.62
Values 2.3 3.2
[164]
HepG2.C3A CYP2U1
Mean 0.173
Standard deviation 0.15
Values 0.068 0.28
[165]
HuH.7 CYP2U1
Mean 0.192
Standard deviation 0.045
Values 0.16 0.17 0.24
[166]
SNU475 CYP2U1
Mean 4.71
Standard deviation 1
Values 5.4 4
[167]
THLE CYP2U1
Mean 9.13
Standard deviation 0.16
Values 9 9.2
[168]
liver CYP2U1
Mean 6.54
Standard deviation 1.6
Values 5.5 8.3 7.4 5
[169]
ref_hepatocyte TBXAS1
Mean 0.896
Standard deviation 0.62
Values 0.56 0.49 0.32 1.7 1.4
[170]
HepG2 TBXAS1
Mean 0.253
Standard deviation 0.096
Values 0.32 0.18
[171]
HepG2.C3A TBXAS1
Mean 0.938
Standard deviation 0.16
Values 1 0.83
[172]
HuH.7 TBXAS1
Mean 0.0986
Standard deviation 0.058
Values 0.12 0.032 0.14
[173]
SNU475 TBXAS1
Mean 2.57
Standard deviation 0.093
Values 2.5 2.6
[174]
THLE TBXAS1
Mean 1.05
Standard deviation 0.095
Values 1.1 0.98
[175]
liver TBXAS1
Mean 4
Standard deviation 1.4
Values 2.1 4.8 4.1 5.1
[176]
ref_hepatocyte CYP11A1
Mean 0.602
Standard deviation 0.44
Values 0.18 0.47 0.44 0.59 1.3
[177]
HepG2 CYP11A1
Mean 0.843
Standard deviation 0.49
Values 1.2 0.49
[178]
HepG2.C3A CYP11A1
Mean 0.131
Standard deviation 0.049
Values 0.17 0.097
[179]
HuH.7 CYP11A1
Mean 0
Standard deviation 0
Values 0 0 0
[180]
SNU475 CYP11A1
Mean 0.115
Standard deviation 0.045
Values 0.083 0.15
[181]
THLE CYP11A1
Mean 2.14
Standard deviation 0.87
Values 2.8 1.5
[182]
liver CYP11A1
Mean 1.18
Standard deviation 0.65
Values 1.4 0.57 2 0.75
[183]
ref_hepatocyte CYP24A1
Mean 0.344
Standard deviation 0.69
Values 1.6 0.15 0 0 0
[184]
HepG2 CYP24A1
Mean 215
Standard deviation 90
Values 2.8e+02 1.5e+02
[185]
HepG2.C3A CYP24A1
Mean 6.56
Standard deviation 2.9
Values 4.5 8.6
[186]
HuH.7 CYP24A1
Mean 0.126
Standard deviation 0.11
Values 0.11 0.24 0.019
[187]
SNU475 CYP24A1
Mean 10.9
Standard deviation 10
Values 3.8 18
[188]
THLE CYP24A1
Mean 0.109
Standard deviation 0.079
Values 0.053 0.16
[189]
liver CYP24A1
Mean 0.00357
Standard deviation 0.0071
Values 0 0.014 0 0
[190]
ref_hepatocyte CYP17A1
Mean 0.208
Standard deviation 0.25
Values 0 0 0.31 0.6 0.13
[191]
HepG2 CYP17A1
Mean 0.0687
Standard deviation 0.024
Values 0.086 0.051
[192]
HepG2.C3A CYP17A1
Mean 1.01
Standard deviation 0.19
Values 1.1 0.88
[193]
HuH.7 CYP17A1
Mean 0.0898
Standard deviation 0.047
Values 0.041 0.13 0.094
[194]
SNU475 CYP17A1
Mean 0.00717
Standard deviation 0.003
Values 0.0093 0.0051
[195]
THLE CYP17A1
Mean 0.00828
Standard deviation 0.0033
Values 0.0059 0.011
[196]
liver CYP17A1
Mean 0.926
Standard deviation 1.4
Values 2.9 0.057 0.21 0.5
[197]
ref_hepatocyte CYP27B1
Mean 0.0505
Standard deviation 0.082
Values 0 0 0.19 0 0.065
[198]
HepG2 CYP27B1
Mean 0.715
Standard deviation 0.14
Values 0.62 0.81
[199]
HepG2.C3A CYP27B1
Mean 1.72
Standard deviation 0.25
Values 1.9 1.5
[200]
HuH.7 CYP27B1
Mean 1.08
Standard deviation 0.18
Values 1.1 0.89 1.3
[201]
SNU475 CYP27B1
Mean 0.211
Standard deviation 0.1
Values 0.14 0.28
[202]
THLE CYP27B1
Mean 0.395
Standard deviation 0.14
Values 0.5 0.29
[203]
liver CYP27B1
Mean 0.228
Standard deviation 0.17
Values 0.071 0.14 0.46 0.24
[204]
ref_hepatocyte CYP26B1
Mean 0.0121
Standard deviation 0.027
Values 0 0 0 0.06 0
[205]
HepG2 CYP26B1
Mean 0.791
Standard deviation 0.35
Values 1 0.54
[206]
HepG2.C3A CYP26B1
Mean 0.0848
Standard deviation 0.092
Values 0.019 0.15
[207]
HuH.7 CYP26B1
Mean 12
Standard deviation 3.7
Values 14 7.7 14
[208]
SNU475 CYP26B1
Mean 2.31
Standard deviation 2.1
Values 0.84 3.8
[209]
THLE CYP26B1
Mean 1.52
Standard deviation 0.59
Values 1.9 1.1
[210]
liver CYP26B1
Mean 0.794
Standard deviation 0.48
Values 0.78 0.43 0.49 1.5
[211]
ref_hepatocyte CYP11B1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[212]
HepG2 CYP11B1
Mean 0.00287
Standard deviation 0.0041
Values 0.0057 0
[213]
HepG2.C3A CYP11B1
Mean 0
Standard deviation 0
Values 0 0
[214]
HuH.7 CYP11B1
Mean 0
Standard deviation 0
Values 0 0 0
[215]
SNU475 CYP11B1
Mean 0
Standard deviation 0
Values 0 0
[216]
THLE CYP11B1
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[217]
liver CYP11B1
Mean 0.00331
Standard deviation 0.0066
Values 0 0 0 0.013
[218]
ref_hepatocyte CYP11B2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[219]
HepG2 CYP11B2
Missing
[220]
HepG2.C3A CYP11B2
Missing
[221]
HuH.7 CYP11B2
Missing
[222]
SNU475 CYP11B2
Missing
[223]
THLE CYP11B2
Missing
[224]
liver CYP11B2
Missing
[225]
ref_hepatocyte FDX2
Missing
[226]
HepG2 FDX2
Missing
[227]
HepG2.C3A FDX2
Missing
[228]
HuH.7 FDX2
Missing
[229]
SNU475 FDX2
Missing
[230]
THLE FDX2
Missing
[231]
liver FDX2
Missing
[232]
ref_hepatocyte CYP26C1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[233]
HepG2 CYP26C1
Mean 0
Standard deviation 0
Values 0 0
[234]
HepG2.C3A CYP26C1
Mean 0
Standard deviation 0
Values 0 0
[235]
HuH.7 CYP26C1
Mean 0.176
Standard deviation 0.084
Values 0.26 0.17 0.094
[236]
SNU475 CYP26C1
Mean 0
Standard deviation 0
Values 0 0
[237]
THLE CYP26C1
Mean 0.0166
Standard deviation 0.0067
Values 0.012 0.021
[238]
liver CYP26C1
Mean 0.0165
Standard deviation 0.033
Values 0 0 0 0.066