REACTOME_MELANIN_BIOSYNTHESIS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 TYRP1 5,6-dihydroxyindole-2-carboxylic acid oxidase [1] -0.81[2] -1.59[3] -2.84[4] 1.13[5] 1.08[6] [7]
2 SLC45A2 Membrane-associated transporter protein [8] -5.20[9] -1.23[10] -0.57[11] -4.87[12] -4.01[13] 0.93[14]
3 OCA2 P protein [15] 1.67[16] 1.74[17] 1.62[18] -7.39[19] -4.95[20] 0.74[21]
4 DCT L-dopachrome tautomerase [22] [23] [24] [25] [26] [27] [28]
5 TYR Tyrosinase [29] [30] [31] [32] [33] [34] [35]
[1]
ref_hepatocyte TYRP1
Mean 0.0326
Standard deviation 0.073
Values 0 0 0.16 0 0
[2]
HepG2 TYRP1
Mean 0.123
Standard deviation 0.029
Values 0.14 0.1
[3]
HepG2.C3A TYRP1
Mean 0.0161
Standard deviation 0.023
Values 0 0.032
[4]
HuH.7 TYRP1
Mean 0.025
Standard deviation 0.025
Values 0.049 0.026 0
[5]
SNU475 TYRP1
Mean 13.8
Standard deviation 8.2
Values 20 8
[6]
THLE TYRP1
Mean 0.788
Standard deviation 0.19
Values 0.66 0.92
[7]
liver TYRP1
Mean 0
Standard deviation 0
Values 0 0 0 0
[8]
ref_hepatocyte SLC45A2
Mean 0.0237
Standard deviation 0.038
Values 0 0 0 0.086 0.033
[9]
HepG2 SLC45A2
Mean 0.00429
Standard deviation 0.0061
Values 0 0.0086
[10]
HepG2.C3A SLC45A2
Mean 0.0151
Standard deviation 0.0062
Values 0.019 0.011
[11]
HuH.7 SLC45A2
Mean 0.0877
Standard deviation 0.065
Values 0.025 0.15 0.084
[12]
SNU475 SLC45A2
Mean 0.157
Standard deviation 0.021
Values 0.17 0.14
[13]
THLE SLC45A2
Mean 0.0169
Standard deviation 0.0013
Values 0.018 0.016
[14]
liver SLC45A2
Mean 0.265
Standard deviation 0.33
Values 0.024 0.26 0.051 0.73
[15]
ref_hepatocyte OCA2
Mean 0.0152
Standard deviation 0.023
Values 0 0 0 0.052 0.024
[16]
HepG2 OCA2
Mean 0.321
Standard deviation 0.26
Values 0.5 0.14
[17]
HepG2.C3A OCA2
Mean 0.0759
Standard deviation 0.016
Values 0.087 0.064
[18]
HuH.7 OCA2
Mean 0.255
Standard deviation 0.33
Values 0.049 0.64 0.075
[19]
SNU475 OCA2
Mean 0.0175
Standard deviation 0.018
Values 0.0046 0.03
[20]
THLE OCA2
Mean 0.00562
Standard deviation 0.00042
Values 0.0059 0.0053
[21]
liver OCA2
Mean 0.149
Standard deviation 0.094
Values 0.071 0.071 0.26 0.2
[22]
ref_hepatocyte DCT
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[23]
HepG2 DCT
Mean 0.0315
Standard deviation 0.045
Values 0.063 0
[24]
HepG2.C3A DCT
Mean 0
Standard deviation 0
Values 0 0
[25]
HuH.7 DCT
Mean 0.0276
Standard deviation 0.033
Values 0 0.064 0.019
[26]
SNU475 DCT
Mean 0.0148
Standard deviation 0.0078
Values 0.0093 0.02
[27]
THLE DCT
Mean 0.0177
Standard deviation 0.025
Values 0.035 0
[28]
liver DCT
Mean 0.0102
Standard deviation 0.013
Values 0 0.014 0 0.026
[29]
ref_hepatocyte TYR
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[30]
HepG2 TYR
Missing
[31]
HepG2.C3A TYR
Missing
[32]
HuH.7 TYR
Missing
[33]
SNU475 TYR
Missing
[34]
THLE TYR
Missing
[35]
liver TYR
Missing