REACTOME_MECP2_REGULATES_NEURONAL_RECEPTORS_AND_CHANNELS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 HDAC1 Histone deacetylase 1 [1] -1.36[2] -0.61[3] 0.14[4] -0.50[5] -1.01[6] -1.59[7]
2 FKBP5 Peptidyl-prolyl cis-trans isomerase FKBP5 [8] -2.32[9] -1.85[10] -3.52[11] -2.22[12] 0.72[13] 1.00[14]
3 MET Hepatocyte growth factor receptor [15] -1.78[16] -1.02[17] -0.32[18] 0.39[19] -1.19[20] -0.16[21]
4 PTPN1 Tyrosine-protein phosphatase non-receptor type 1 [22] -0.75[23] -0.35[24] -0.76[25] 0.68[26] -0.32[27] -1.43[28]
5 SLC2A3 Solute carrier family 2, facilitated glucose transporter member 3 [29] 2.76[30] 0.54[31] -5.91[32] -2.89[33] -1.01[34] -2.41[35]
6 HDAC2 Histone deacetylase 2 [36] -0.14[37] 1.91[38] 1.36[39] 1.01[40] 0.86[41] -0.92[42]
7 MECP2 Methyl-CpG-binding protein 2 [43] -1.14[44] -0.12[45] 0.15[46] 0.44[47] 0.25[48] -0.30[49]
8 SIN3A Paired amphipathic helix protein Sin3a [50] -0.49[51] 0.33[52] 1.60[53] 0.84[54] 0.30[55] 0.16[56]
9 CREB1 Cyclic AMP-responsive element-binding protein 1 [57] -0.14[58] 1.75[59] 2.30[60] 1.39[61] 1.04[62] 1.22[63]
10 PTPN4 Tyrosine-protein phosphatase non-receptor type 4 [64] -0.51[65] 1.78[66] 0.95[67] 1.24[68] 0.38[69] 2.12[70]
11 NOTCH1 Neurogenic locus notch homolog protein 1 [71] 0.04[72] -0.39[73] 1.01[74] 1.44[75] 1.50[76] 3.51[77]
12 GPRIN1 G protein-regulated inducer of neurite outgrowth 1 [78] 2.95[79] 1.63[80] 2.96[81] 2.92[82] 2.81[83] -0.32[84]
13 GRIN2B Glutamate receptor ionotropic, NMDA 2B [85] -4.32[86] [87] [88] -0.06[89] -3.17[90] 0.74[91]
14 OPRM1 Mu-type opioid receptor [92] [93] -3.53[94] [95] [96] -4.62[97] -3.61[98]
15 GRIN2A Glutamate receptor ionotropic, NMDA 2A [99] [100] [101] -1.67[102] 7.91[103] 0.14[104] 6.91[105]
16 TRPC3 Short transient receptor potential channel 3 [106] [107] [108] [109] [110] [111] [112]
17 OPRK1 Kappa-type opioid receptor [113] [114] [115] [116] [117] [118] [119]
18 GRIA2 Glutamate receptor 2 [120] [121] [122] [123] [124] [125] [126]
[1]
ref_hepatocyte HDAC1
Mean 20.8
Standard deviation 4.1
Values 22 28 19 18 18
[2]
HepG2 HDAC1
Mean 65.4
Standard deviation 11
Values 73 58
[3]
HepG2.C3A HDAC1
Mean 58.9
Standard deviation 2.3
Values 57 60
[4]
HuH.7 HDAC1
Mean 90.9
Standard deviation 22
Values 94 68 1.1e+02
[5]
SNU475 HDAC1
Mean 59.8
Standard deviation 8
Values 65 54
[6]
THLE HDAC1
Mean 57.8
Standard deviation 6.8
Values 53 63
[7]
liver HDAC1
Mean 21.5
Standard deviation 6.8
Values 25 18 29 14
[8]
ref_hepatocyte FKBP5
Mean 18.4
Standard deviation 11
Values 10 28 7.4 31 15
[9]
HepG2 FKBP5
Mean 29.7
Standard deviation 0.56
Values 29 30
[10]
HepG2.C3A FKBP5
Mean 22
Standard deviation 6.9
Values 17 27
[11]
HuH.7 FKBP5
Mean 6.3
Standard deviation 3.2
Values 8.7 2.7 7.5
[12]
SNU475 FKBP5
Mean 16
Standard deviation 1.5
Values 17 15
[13]
THLE FKBP5
Mean 170
Standard deviation 22
Values 1.5e+02 1.9e+02
[14]
liver FKBP5
Mean 114
Standard deviation 13
Values 1.1e+02 98 1.3e+02 1.1e+02
[15]
ref_hepatocyte MET
Mean 12.9
Standard deviation 12
Values 6.9 32 16 3.7 5.7
[16]
HepG2 MET
Mean 30.2
Standard deviation 2.7
Values 32 28
[17]
HepG2.C3A MET
Mean 27.5
Standard deviation 6.5
Values 23 32
[18]
HuH.7 MET
Mean 40.8
Standard deviation 7.3
Values 43 47 33
[19]
SNU475 MET
Mean 68.7
Standard deviation 7.1
Values 64 74
[20]
THLE MET
Mean 31.7
Standard deviation 2
Values 33 30
[21]
liver MET
Mean 35.9
Standard deviation 13
Values 27 46 22 48
[22]
ref_hepatocyte PTPN1
Mean 8.72
Standard deviation 6.8
Values 20 10 6.8 4.1 2.6
[23]
HepG2 PTPN1
Mean 41.8
Standard deviation 5
Values 38 45
[24]
HepG2.C3A PTPN1
Mean 29.5
Standard deviation 3
Values 27 32
[25]
HuH.7 PTPN1
Mean 20.4
Standard deviation 3.4
Values 24 18 19
[26]
SNU475 PTPN1
Mean 56.7
Standard deviation 1.9
Values 55 58
[27]
THLE PTPN1
Mean 39.1
Standard deviation 7.5
Values 34 44
[28]
liver PTPN1
Mean 10
Standard deviation 0.98
Values 11 10 11 8.6
[29]
ref_hepatocyte SLC2A3
Mean 7.61
Standard deviation 15
Values 34 0.19 1.5 0.66 1.6
[30]
HepG2 SLC2A3
Mean 414
Standard deviation 0.7
Values 4.1e+02 4.1e+02
[31]
HepG2.C3A SLC2A3
Mean 47.6
Standard deviation 5.9
Values 43 52
[32]
HuH.7 SLC2A3
Mean 0.499
Standard deviation 0.18
Values 0.43 0.71 0.36
[33]
SNU475 SLC2A3
Mean 4.19
Standard deviation 2
Values 2.7 5.6
[34]
THLE SLC2A3
Mean 21.1
Standard deviation 0.92
Values 22 20
[35]
liver SLC2A3
Mean 4.42
Standard deviation 1.7
Values 1.9 5.9 4.8 5.2
[36]
ref_hepatocyte HDAC2
Mean 6.67
Standard deviation 4.2
Values 13 9.1 4 4.1 3.3
[37]
HepG2 HDAC2
Mean 48.7
Standard deviation 9.3
Values 42 55
[38]
HepG2.C3A HDAC2
Mean 109
Standard deviation 22
Values 93 1.2e+02
[39]
HuH.7 HDAC2
Mean 67.5
Standard deviation 9.6
Values 70 57 76
[40]
SNU475 HDAC2
Mean 54.8
Standard deviation 1.8
Values 56 54
[41]
THLE HDAC2
Mean 67.7
Standard deviation 2.7
Values 66 70
[42]
liver HDAC2
Mean 10.9
Standard deviation 4.8
Values 15 7.3 15 6.2
[43]
ref_hepatocyte MECP2
Mean 4.65
Standard deviation 3.2
Values 0.97 2.9 9 6.8 3.6
[44]
HepG2 MECP2
Mean 17
Standard deviation 0.35
Values 17 17
[45]
HepG2.C3A MECP2
Mean 18.5
Standard deviation 2.1
Values 20 17
[46]
HuH.7 MECP2
Mean 20.4
Standard deviation 2.7
Values 24 19 19
[47]
SNU475 MECP2
Mean 25.6
Standard deviation 3.5
Values 28 23
[48]
THLE MECP2
Mean 30.9
Standard deviation 2.7
Values 29 33
[49]
liver MECP2
Mean 11.7
Standard deviation 2.4
Values 14 9.6 9.8 14
[50]
ref_hepatocyte SIN3A
Mean 3.84
Standard deviation 1.6
Values 4.4 6 4.1 2.3 2.4
[51]
HepG2 SIN3A
Mean 22
Standard deviation 0.2
Values 22 22
[52]
HepG2.C3A SIN3A
Mean 20.9
Standard deviation 1.9
Values 22 20
[53]
HuH.7 SIN3A
Mean 46
Standard deviation 6.9
Values 54 44 41
[54]
SNU475 SIN3A
Mean 28
Standard deviation 1.4
Values 27 29
[55]
THLE SIN3A
Mean 26.4
Standard deviation 5.5
Values 23 30
[56]
liver SIN3A
Mean 13.3
Standard deviation 1.8
Values 13 15 11 14
[57]
ref_hepatocyte CREB1
Mean 1.8
Standard deviation 1.2
Values 3.7 2.1 1.5 0.96 0.81
[58]
HepG2 CREB1
Mean 13.1
Standard deviation 2.8
Values 11 15
[59]
HepG2.C3A CREB1
Mean 26.1
Standard deviation 3.2
Values 24 28
[60]
HuH.7 CREB1
Mean 35.1
Standard deviation 4
Values 38 36 31
[61]
SNU475 CREB1
Mean 19.3
Standard deviation 0.081
Values 19 19
[62]
THLE CREB1
Mean 20.8
Standard deviation 2.1
Values 22 19
[63]
liver CREB1
Mean 13
Standard deviation 3.1
Values 12 16 9.3 15
[64]
ref_hepatocyte PTPN4
Mean 0.856
Standard deviation 0.2
Values 1 1.1 0.64 0.68 0.85
[65]
HepG2 PTPN4
Mean 4.83
Standard deviation 2.1
Values 3.3 6.3
[66]
HepG2.C3A PTPN4
Mean 12.7
Standard deviation 0.71
Values 12 13
[67]
HuH.7 PTPN4
Mean 6.55
Standard deviation 0.84
Values 7.5 6 6.1
[68]
SNU475 PTPN4
Mean 8.25
Standard deviation 1.2
Values 9.1 7.4
[69]
THLE PTPN4
Mean 6.24
Standard deviation 1.7
Values 7.4 5
[70]
liver PTPN4
Mean 11.5
Standard deviation 6.1
Values 7.4 17 5.3 16
[71]
ref_hepatocyte NOTCH1
Mean 0.644
Standard deviation 0.25
Values 0.33 0.55 0.55 0.91 0.89
[72]
HepG2 NOTCH1
Mean 5.33
Standard deviation 3.7
Values 8 2.7
[73]
HepG2.C3A NOTCH1
Mean 2.12
Standard deviation 0.1
Values 2.1 2.2
[74]
HuH.7 NOTCH1
Mean 5.14
Standard deviation 1.4
Values 5.4 6.4 3.6
[75]
SNU475 NOTCH1
Mean 7.09
Standard deviation 0.64
Values 6.6 7.5
[76]
THLE NOTCH1
Mean 10.2
Standard deviation 2.2
Values 8.6 12
[77]
liver NOTCH1
Mean 22.8
Standard deviation 16
Values 10 31 8.8 41
[78]
ref_hepatocyte GPRIN1
Mean 0.119
Standard deviation 0.12
Values 0.082 0.3 0.16 0.026 0.024
[79]
HepG2 GPRIN1
Mean 7.4
Standard deviation 1.5
Values 8.5 6.3
[80]
HepG2.C3A GPRIN1
Mean 1.6
Standard deviation 0.33
Values 1.4 1.8
[81]
HuH.7 GPRIN1
Mean 3.67
Standard deviation 1.9
Values 5.1 1.6 4.3
[82]
SNU475 GPRIN1
Mean 3.68
Standard deviation 0.091
Values 3.6 3.7
[83]
THLE GPRIN1
Mean 4.67
Standard deviation 0.16
Values 4.6 4.8
[84]
liver GPRIN1
Mean 0.295
Standard deviation 0.2
Values 0.047 0.39 0.23 0.52
[85]
ref_hepatocyte GRIN2B
Mean 0.0213
Standard deviation 0.039
Values 0 0 0 0.017 0.089
[86]
HepG2 GRIN2B
Mean 0.00858
Standard deviation 0.012
Values 0 0.017
[87]
HepG2.C3A GRIN2B
Mean 0
Standard deviation 0
Values 0 0
[88]
HuH.7 GRIN2B
Mean 0
Standard deviation 0
Values 0 0 0
[89]
SNU475 GRIN2B
Mean 0.0833
Standard deviation 0.046
Values 0.12 0.051
[90]
THLE GRIN2B
Mean 0.0133
Standard deviation 0.019
Values 0 0.027
[91]
liver GRIN2B
Mean 0.11
Standard deviation 0.05
Values 0.12 0.1 0.051 0.17
[92]
ref_hepatocyte OPRM1
Mean 0.013
Standard deviation 0.029
Values 0 0 0 0 0.065
[93]
HepG2 OPRM1
Mean 0
Standard deviation 0
Values 0 0
[94]
HepG2.C3A OPRM1
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[95]
HuH.7 OPRM1
Mean 0
Standard deviation 0
Values 0 0 0
[96]
SNU475 OPRM1
Mean 0
Standard deviation 0
Values 0 0
[97]
THLE OPRM1
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[98]
liver OPRM1
Mean 0.00331
Standard deviation 0.0066
Values 0 0 0 0.013
[99]
ref_hepatocyte GRIN2A
Mean 0.00172
Standard deviation 0.0039
Values 0 0 0 0.0086 0
[100]
HepG2 GRIN2A
Mean 0
Standard deviation 0
Values 0 0
[101]
HepG2.C3A GRIN2A
Mean 0
Standard deviation 0
Values 0 0
[102]
HuH.7 GRIN2A
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[103]
SNU475 GRIN2A
Mean 1.69
Standard deviation 0.46
Values 1.4 2
[104]
THLE GRIN2A
Mean 0.0106
Standard deviation 0.015
Values 0 0.021
[105]
liver GRIN2A
Mean 0.641
Standard deviation 0.48
Values 0.28 0.74 0.26 1.3
[106]
ref_hepatocyte TRPC3
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[107]
HepG2 TRPC3
Mean 0
Standard deviation 0
Values 0 0
[108]
HepG2.C3A TRPC3
Mean 0
Standard deviation 0
Values 0 0
[109]
HuH.7 TRPC3
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[110]
SNU475 TRPC3
Mean 0.0948
Standard deviation 0.088
Values 0.032 0.16
[111]
THLE TRPC3
Mean 0.612
Standard deviation 0.03
Values 0.63 0.59
[112]
liver TRPC3
Mean 0.107
Standard deviation 0.081
Values 0.071 0.23 0.051 0.079
[113]
ref_hepatocyte OPRK1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[114]
HepG2 OPRK1
Mean 0.0401
Standard deviation 0.032
Values 0.063 0.017
[115]
HepG2.C3A OPRK1
Mean 0.0618
Standard deviation 0.019
Values 0.049 0.075
[116]
HuH.7 OPRK1
Mean 0.0255
Standard deviation 0.029
Values 0 0.058 0.019
[117]
SNU475 OPRK1
Mean 0.0219
Standard deviation 0.0048
Values 0.019 0.025
[118]
THLE OPRK1
Mean 0.0175
Standard deviation 0.017
Values 0.03 0.0053
[119]
liver OPRK1
Mean 0.0807
Standard deviation 0.049
Values 0.024 0.14 0.077 0.079
[120]
ref_hepatocyte GRIA2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[121]
HepG2 GRIA2
Mean 0
Standard deviation 0
Values 0 0
[122]
HepG2.C3A GRIA2
Mean 0
Standard deviation 0
Values 0 0
[123]
HuH.7 GRIA2
Mean 0.427
Standard deviation 0.1
Values 0.36 0.55 0.37
[124]
SNU475 GRIA2
Mean 0.142
Standard deviation 0.036
Values 0.17 0.12
[125]
THLE GRIA2
Mean 0
Standard deviation 0
Values 0 0
[126]
liver GRIA2
Mean 0.00688
Standard deviation 0.008
Values 0 0.014 0 0.013