REACTOME_MATURATION_OF_SARS_COV_2_SPIKE_PROTEIN |
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Order |
Gene |
Description |
ref_hepatocyte |
HepG2 |
HepG2.C3A |
HuH.7 |
SNU475 |
THLE |
liver |
1 |
DAD1 |
Dolichyl-diphosphooligosaccharide--protein
glycosyltransferase subunit DAD1 |
-1.50[1] |
-3.19[2] |
-3.35[3] |
-2.83[4] |
-2.95[5] |
-2.79[6] |
2 |
CANX |
Calnexin |
[7] |
0.02[8] |
0.41[9] |
0.44[10] |
0.79[11] |
0.60[12] |
0.85[13] |
3 |
RPN1 |
Dolichyl-diphosphooligosaccharide--protein
glycosyltransferase subunit 1 |
-0.53[14] |
-0.78[15] |
-0.80[16] |
-0.71[17] |
-0.44[18] |
-0.31[19] |
4 |
ST6GAL1 |
Beta-galactoside alpha-2,6-sialyltransferase 1 |
[20] |
-1.26[21] |
-0.17[22] |
0.01[23] |
-7.53[24] |
-5.78[25] |
1.30[26] |
5 |
RPN2 |
Dolichyl-diphosphooligosaccharide--protein
glycosyltransferase subunit 2 |
1.22[27] |
1.06[28] |
0.48[29] |
0.50[30] |
0.26[31] |
-0.09[32] |
6 |
DDOST |
Dolichyl-diphosphooligosaccharide--protein
glycosyltransferase 48 kDa subunit |
0.50[33] |
1.36[34] |
0.18[35] |
0.56[36] |
0.54[37] |
-0.59[38] |
7 |
MGAT4B |
Alpha-1,3-mannosyl-glycoprotein
4-beta-N-acetylglucosaminyltransferase B |
-0.44[39] |
-0.95[40] |
-1.16[41] |
-0.30[42] |
-0.11[43] |
-1.87[44] |
8 |
PRKCSH |
Glucosidase 2 subunit beta |
[45] |
-0.16[46] |
-0.74[47] |
0.72[48] |
-0.42[49] |
0.01[50] |
-1.93[51] |
9 |
STT3A |
Dolichyl-diphosphooligosaccharide--protein
glycosyltransferase subunit STT3A |
0.83[52] |
-0.09[53] |
-0.37[54] |
0.57[55] |
0.27[56] |
-0.25[57] |
10 |
GANAB |
Neutral alpha-glucosidase AB |
[58] |
0.72[59] |
0.33[60] |
1.70[61] |
1.35[62] |
1.82[63] |
0.51[64] |
11 |
MGAT1 |
Alpha-1,3-mannosyl-glycoprotein
2-beta-N-acetylglucosaminyltransferase |
-0.72[65] |
-0.49[66] |
-0.03[67] |
-0.94[68] |
-0.66[69] |
-0.12[70] |
12 |
MAGT1 |
Magnesium transporter protein 1 |
[71] |
-0.15[72] |
0.08[73] |
-1.13[74] |
0.89[75] |
0.77[76] |
0.86[77] |
13 |
ST3GAL1 |
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase
1 |
-0.40[78] |
-1.29[79] |
-0.36[80] |
0.18[81] |
0.07[82] |
1.86[83] |
14 |
EDEM2 |
ER degradation-enhancing alpha-mannosidase-like protein 2 |
[84] |
0.42[85] |
0.09[86] |
-1.43[87] |
-0.32[88] |
-1.40[89] |
-0.86[90] |
15 |
MOGS |
Mannosyl-oligosaccharide glucosidase |
[91] |
0.62[92] |
0.71[93] |
-0.16[94] |
-0.27[95] |
-0.08[96] |
-0.34[97] |
16 |
MGAT2 |
Alpha-1,6-mannosyl-glycoprotein
2-beta-N-acetylglucosaminyltransferase |
-0.49[98] |
-0.06[99] |
0.10[100] |
-0.21[101] |
0.17[102] |
-0.34[103] |
17 |
MAN1B1 |
Endoplasmic reticulum
mannosyl-oligosaccharide 1,2-alpha-mannosidase |
0.57[104] |
0.15[105] |
0.19[106] |
0.33[107] |
-0.01[108] |
-0.64[109] |
18 |
MAN2A1 |
Alpha-mannosidase 2 |
[110] |
-0.17[111] |
0.67[112] |
1.19[113] |
-0.89[114] |
-0.49[115] |
1.36[116] |
19 |
ST3GAL4 |
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase
4 |
-1.00[117] |
-1.55[118] |
-3.82[119] |
0.79[120] |
0.08[121] |
-1.65[122] |
20 |
ST3GAL2 |
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase
2 |
1.63[123] |
1.38[124] |
2.25[125] |
2.64[126] |
1.84[127] |
0.19[128] |
21 |
ST6GALNAC4 |
Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide
alpha-2,6-sialyltransferase |
1.46[129] |
1.39[130] |
-1.33[131] |
0.43[132] |
0.81[133] |
-1.47[134] |
22 |
ST3GAL3 |
CMP-N-acetylneuraminate-beta-1,4-galactoside
alpha-2,3-sialyltransferase |
-0.33[135] |
-0.17[136] |
-0.32[137] |
-0.04[138] |
0.41[139] |
-0.88[140] |
23 |
MGAT4A |
Alpha-1,3-mannosyl-glycoprotein
4-beta-N-acetylglucosaminyltransferase A |
1.60[141] |
3.36[142] |
3.96[143] |
-1.68[144] |
-1.52[145] |
0.99[146] |
24 |
ST6GALNAC2 |
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
[147] |
-3.45[148] |
-2.84[149] |
-4.12[150] |
-2.56[151] |
-2.25[152] |
-2.87[153] |
25 |
MGAT5 |
Alpha-1,6-mannosylglycoprotein
6-beta-N-acetylglucosaminyltransferase A |
3.55[154] |
3.16[155] |
3.14[156] |
3.45[157] |
3.20[158] |
1.32[159] |
26 |
FUT8 |
Alpha-(1,6)-fucosyltransferase |
[160] |
3.43[161] |
1.13[162] |
2.17[163] |
3.97[164] |
4.78[165] |
1.08[166] |
27 |
TUSC3 |
Tumor suppressor candidate 3 |
[167] |
0.78[168] |
-1.69[169] |
-4.76[170] |
6.07[171] |
5.70[172] |
2.17[173] |
28 |
ST6GALNAC3 |
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 |
[174] |
-6.01[175] |
[176] |
-2.05[177] |
3.55[178] |
0.72[179] |
4.48[180] |
29 |
MGAT4C |
Alpha-1,3-mannosyl-glycoprotein
4-beta-N-acetylglucosaminyltransferase C |
[181] |
[182] |
[183] |
[184] |
[185] |
[186] |
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