REACTOME_LYSOSPHINGOLIPID_AND_LPA_RECEPTORS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 S1PR1 Sphingosine 1-phosphate receptor 1 [1] -6.77[2] [3] -5.03[4] -4.18[5] -3.21[6] -0.43[7]
2 LPAR3 Lysophosphatidic acid receptor 3 [8] -4.18[9] -3.52[10] 2.26[11] -3.82[12] -4.41[13] -9.50[14]
3 S1PR2 Sphingosine 1-phosphate receptor 2 [15] 2.42[16] 2.21[17] 1.17[18] -0.14[19] -1.54[20] 1.34[21]
4 S1PR3 Sphingosine 1-phosphate receptor 3 [22] -0.28[23] -1.19[24] -3.23[25] 2.86[26] 3.21[27] 0.91[28]
5 LPAR2 Lysophosphatidic acid receptor 2 [29] 2.06[30] 2.83[31] 0.60[32] -0.55[33] -1.27[34] -0.43[35]
6 LPAR5 Lysophosphatidic acid receptor 5 [36] 1.88[37] 1.05[38] -7.07[39] -4.75[40] -2.56[41] -0.17[42]
7 S1PR5 Sphingosine 1-phosphate receptor 5 [43] 0.87[44] 2.48[45] 1.74[46] 2.45[47] -0.01[48] -1.26[49]
8 S1PR4 Sphingosine 1-phosphate receptor 4 [50] 1.40[51] -0.36[52] -3.54[53] -7.15[54] -5.47[55] 1.31[56]
9 LPAR1 Lysophosphatidic acid receptor 1 [57] -2.99[58] [59] -2.99[60] 4.01[61] 3.65[62] 2.49[63]
10 PLPPR4 Phospholipid phosphatase-related protein type 4 [64] [65] [66] [67] [68] [69] [70]
11 PLPPR1 Phospholipid phosphatase-related protein type 1 [71] [72] [73] [74] [75] [76] [77]
12 PLPPR2 Phospholipid phosphatase-related protein type 2 [78] [79] [80] [81] [82] [83] [84]
13 PLPPR3 Phospholipid phosphatase-related protein type 3 [85] [86] [87] [88] [89] [90] [91]
14 PLPPR5 Phospholipid phosphatase-related protein type 5 [92] [93] [94] [95] [96] [97] [98]

[1]
ref_hepatocyte S1PR1
Mean 2.72
Standard deviation 2
Values 0 1.4 3.8 4.9 3.5
[2]
HepG2 S1PR1
Mean 0.0179
Standard deviation 0.017
Values 0.0057 0.03
[3]
HepG2.C3A S1PR1
Mean 0
Standard deviation 0
Values 0 0
[4]
HuH.7 S1PR1
Mean 0.51
Standard deviation 0.036
Values 0.49 0.55 0.49
[5]
SNU475 S1PR1
Mean 0.855
Standard deviation 0.22
Values 0.7 1
[6]
THLE S1PR1
Mean 2.99
Standard deviation 0.015
Values 3 3
[7]
liver S1PR1
Mean 7.88
Standard deviation 2.5
Values 10 5 9.8 6.7
[8]
ref_hepatocyte LPAR3
Mean 0.615
Standard deviation 1.3
Values 0 0.07 2.9 0.078 0.041
[9]
HepG2 LPAR3
Mean 0.0243
Standard deviation 0.026
Values 0.0057 0.043
[10]
HepG2.C3A LPAR3
Mean 0.0307
Standard deviation 0.0021
Values 0.029 0.032
[11]
HuH.7 LPAR3
Mean 18.1
Standard deviation 3.4
Values 21 19 14
[12]
SNU475 LPAR3
Mean 0.248
Standard deviation 0.25
Values 0.07 0.43
[13]
THLE LPAR3
Mean 0.295
Standard deviation 0.026
Values 0.31 0.28
[14]
liver LPAR3
Mean 0.00331
Standard deviation 0.0066
Values 0 0 0 0.013
[15]
ref_hepatocyte S1PR2
Mean 0.495
Standard deviation 0.34
Values 0.13 0.31 0.58 1 0.43
[16]
HepG2 S1PR2
Mean 1.9
Standard deviation 0.97
Values 2.6 1.2
[17]
HepG2.C3A S1PR2
Mean 1.31
Standard deviation 0.29
Values 1.5 1.1
[18]
HuH.7 S1PR2
Mean 6.83
Standard deviation 0.43
Values 7.2 7 6.4
[19]
SNU475 S1PR2
Mean 2.54
Standard deviation 0.063
Values 2.6 2.5
[20]
THLE S1PR2
Mean 1.73
Standard deviation 0.11
Values 1.7 1.8
[21]
liver S1PR2
Mean 4.88
Standard deviation 2.7
Values 8.2 2.2 5.8 3.3
[22]
ref_hepatocyte S1PR3
Mean 0.365
Standard deviation 0.38
Values 0 0.17 0.78 0.77 0.11
[23]
HepG2 S1PR3
Mean 0.215
Standard deviation 0.02
Values 0.23 0.2
[24]
HepG2.C3A S1PR3
Mean 0.0915
Standard deviation 0.0081
Values 0.097 0.086
[25]
HuH.7 S1PR3
Mean 0.239
Standard deviation 0.08
Values 0.32 0.24 0.16
[26]
SNU475 S1PR3
Mean 15.1
Standard deviation 0.43
Values 15 15
[27]
THLE S1PR3
Mean 34.4
Standard deviation 3.4
Values 37 32
[28]
liver S1PR3
Mean 2.68
Standard deviation 0.32
Values 2.4 2.4 2.9 3
[29]
ref_hepatocyte LPAR2
Mean 0.201
Standard deviation 0.16
Values 0.4 0.26 0 0.078 0.27
[30]
HepG2 LPAR2
Mean 0.598
Standard deviation 0.28
Values 0.8 0.4
[31]
HepG2.C3A LPAR2
Mean 0.817
Standard deviation 0.4
Values 1.1 0.54
[32]
HuH.7 LPAR2
Mean 1.86
Standard deviation 0.46
Values 1.7 1.5 2.4
[33]
SNU475 LPAR2
Mean 0.776
Standard deviation 0.051
Values 0.81 0.74
[34]
THLE LPAR2
Mean 0.846
Standard deviation 0.067
Values 0.89 0.8
[35]
liver LPAR2
Mean 0.578
Standard deviation 0.29
Values 0.68 0.14 0.74 0.74
[36]
ref_hepatocyte LPAR5
Mean 0.166
Standard deviation 0.16
Values 0.17 0 0.079 0.16 0.42
[37]
HepG2 LPAR5
Mean 0.439
Standard deviation 0.17
Values 0.56 0.32
[38]
HepG2.C3A LPAR5
Mean 0.196
Standard deviation 0.071
Values 0.15 0.25
[39]
HuH.7 LPAR5
Mean 0.00761
Standard deviation 0.0083
Values 0.016 0.0064 0
[40]
SNU475 LPAR5
Mean 0.035
Standard deviation 0.036
Values 0.0093 0.061
[41]
THLE LPAR5
Mean 0.287
Standard deviation 0.18
Values 0.16 0.41
[42]
liver LPAR5
Mean 0.574
Standard deviation 0.16
Values 0.61 0.4 0.77 0.52
[43]
ref_hepatocyte S1PR5
Mean 0.0773
Standard deviation 0.11
Values 0 0.14 0 0 0.24
[44]
HepG2 S1PR5
Mean 0.101
Standard deviation 0.1
Values 0.17 0.03
[45]
HepG2.C3A S1PR5
Mean 0.246
Standard deviation 0.12
Values 0.33 0.16
[46]
HuH.7 S1PR5
Mean 1.58
Standard deviation 0.11
Values 1.5 1.5 1.7
[47]
SNU475 S1PR5
Mean 2.4
Standard deviation 0.14
Values 2.5 2.3
[48]
THLE S1PR5
Mean 0.782
Standard deviation 0.015
Values 0.79 0.77
[49]
liver S1PR5
Mean 0.125
Standard deviation 0.045
Values 0.14 0.1 0.18 0.079
[50]
ref_hepatocyte S1PR4
Mean 0.0579
Standard deviation 0.089
Values 0 0 0 0.086 0.2
[51]
HepG2 S1PR4
Mean 0.11
Standard deviation 0.088
Values 0.17 0.047
[52]
HepG2.C3A S1PR4
Mean 0.0258
Standard deviation 0.009
Values 0.019 0.032
[53]
HuH.7 S1PR4
Mean 0.0306
Standard deviation 0.011
Values 0.041 0.032 0.019
[54]
SNU475 S1PR4
Mean 0.00232
Standard deviation 0.0033
Values 0.0046 0
[55]
THLE S1PR4
Mean 0.0133
Standard deviation 0.019
Values 0 0.027
[56]
liver S1PR4
Mean 0.557
Standard deviation 0.3
Values 0.87 0.24 0.36 0.75
[57]
ref_hepatocyte LPAR1
Mean 0.0554
Standard deviation 0.095
Values 0 0 0.22 0 0.057
[58]
HepG2 LPAR1
Mean 0.00501
Standard deviation 0.001
Values 0.0057 0.0043
[59]
HepG2.C3A LPAR1
Mean 0
Standard deviation 0
Values 0 0
[60]
HuH.7 LPAR1
Mean 0.0429
Standard deviation 0.013
Values 0.049 0.051 0.028
[61]
SNU475 LPAR1
Mean 5.08
Standard deviation 0.17
Values 5.2 5
[62]
THLE LPAR1
Mean 7.07
Standard deviation 1.8
Values 8.3 5.8
[63]
liver LPAR1
Mean 1.21
Standard deviation 0.54
Values 0.63 1.1 1.2 1.9
[64]
ref_hepatocyte PLPPR4
Missing
[65]
HepG2 PLPPR4
Missing
[66]
HepG2.C3A PLPPR4
Missing
[67]
HuH.7 PLPPR4
Missing
[68]
SNU475 PLPPR4
Missing
[69]
THLE PLPPR4
Missing
[70]
liver PLPPR4
Missing
[71]
ref_hepatocyte PLPPR1
Missing
[72]
HepG2 PLPPR1
Missing
[73]
HepG2.C3A PLPPR1
Missing
[74]
HuH.7 PLPPR1
Missing
[75]
SNU475 PLPPR1
Missing
[76]
THLE PLPPR1
Missing
[77]
liver PLPPR1
Missing
[78]
ref_hepatocyte PLPPR2
Missing
[79]
HepG2 PLPPR2
Missing
[80]
HepG2.C3A PLPPR2
Missing
[81]
HuH.7 PLPPR2
Missing
[82]
SNU475 PLPPR2
Missing
[83]
THLE PLPPR2
Missing
[84]
liver PLPPR2
Missing
[85]
ref_hepatocyte PLPPR3
Missing
[86]
HepG2 PLPPR3
Missing
[87]
HepG2.C3A PLPPR3
Missing
[88]
HuH.7 PLPPR3
Missing
[89]
SNU475 PLPPR3
Missing
[90]
THLE PLPPR3
Missing
[91]
liver PLPPR3
Missing
[92]
ref_hepatocyte PLPPR5
Missing
[93]
HepG2 PLPPR5
Missing
[94]
HepG2.C3A PLPPR5
Missing
[95]
HuH.7 PLPPR5
Missing
[96]
SNU475 PLPPR5
Missing
[97]
THLE PLPPR5
Missing
[98]
liver PLPPR5
Missing