REACTOME_LYSOSOME_VESICLE_BIOGENESIS | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | HSPA8 | Heat shock cognate 71 kDa protein | [1] | 0.24[2] | 0.39[3] | -0.35[4] | 0.43[5] | 0.16[6] | -0.31[7] |
2 | ARF1 | ADP-ribosylation factor 1 | [8] | -0.63[9] | -0.28[10] | 0.06[11] | -0.14[12] | -0.43[13] | 0.08[14] |
3 | CLTA | Clathrin light chain A | [15] | -1.32[16] | -1.35[17] | -1.28[18] | -1.99[19] | -1.59[20] | -2.50[21] |
4 | CTSZ | Cathepsin Z | [22] | -9.76[23] | -9.24[24] | -2.26[25] | -1.81[26] | -1.84[27] | -1.62[28] |
5 | VAMP8 | Vesicle-associated membrane protein 8 | [29] | -2.01[30] | -0.73[31] | -2.21[32] | -4.36[33] | -3.01[34] | -1.60[35] |
6 | CHMP2A | Charged multivesicular body protein 2a | [36] | -2.54[37] | -2.88[38] | -3.11[39] | -1.76[40] | -2.48[41] | -1.37[42] |
7 | APP | Amyloid-beta A4 protein | [43] | 0.94[44] | 0.53[45] | 1.15[46] | 1.25[47] | 1.69[48] | 0.91[49] |
8 | BLOC1S1 | Biogenesis of lysosome-related organelles complex 1 subunit 1 | [50] | -3.85[51] | -2.89[52] | -3.23[53] | -4.01[54] | -3.65[55] | -2.04[56] |
9 | CLTB | Clathrin light chain B | [57] | -0.01[58] | -1.87[59] | -2.10[60] | -2.18[61] | -1.78[62] | -1.53[63] |
10 | TXNDC5 | Thioredoxin domain-containing protein 5 | [64] | -2.70[65] | -2.78[66] | -4.16[67] | -3.86[68] | -3.98[69] | -5.75[70] |
11 | M6PR | Cation-dependent mannose-6-phosphate receptor | [71] | 0.05[72] | -0.75[73] | -0.05[74] | -1.34[75] | -0.15[76] | -0.66[77] |
12 | CLTC | Clathrin heavy chain 1 | [78] | 2.17[79] | 2.42[80] | 2.55[81] | 2.15[82] | 2.32[83] | 3.23[84] |
13 | AP1S1 | AP-1 complex subunit sigma-1A | [85] | -0.45[86] | -0.61[87] | -0.26[88] | -0.53[89] | -0.72[90] | -2.03[91] |
14 | AP1M1 | AP-1 complex subunit mu-1 | [92] | 0.54[93] | 0.33[94] | 1.35[95] | -0.06[96] | 0.11[97] | 0.69[98] |
15 | HGS | Hepatocyte growth factor-regulated tyrosine kinase substrate | [99] | 1.45[100] | 1.10[101] | 0.54[102] | 0.96[103] | 0.92[104] | 0.00[105] |
16 | DNM2 | Dynamin-2 | [106] | 2.57[107] | 1.65[108] | 1.87[109] | 1.42[110] | 1.72[111] | 1.54[112] |
17 | GNS | N-acetylglucosamine-6-sulfatase | [113] | 2.34[114] | 2.13[115] | 2.84[116] | 2.63[117] | 2.93[118] | 3.01[119] |
18 | VAMP7 | Vesicle-associated membrane protein 7 | [120] | [121] | [122] | [123] | [124] | [125] | [126] |
19 | AP1B1 | AP-1 complex subunit beta-1 | [127] | 1.67[128] | 1.15[129] | 3.02[130] | 1.67[131] | 1.51[132] | 2.26[133] |
20 | DNASE2 | Deoxyribonuclease-2-alpha | [134] | 0.42[135] | 0.90[136] | 1.56[137] | -0.34[138] | 0.65[139] | -0.34[140] |
21 | AP1G1 | AP-1 complex subunit gamma-1 | [141] | 1.96[142] | 2.39[143] | 2.76[144] | 2.18[145] | 2.05[146] | 2.70[147] |
22 | VAMP2 | Vesicle-associated membrane protein 2 | [148] | -0.79[149] | -0.28[150] | 0.02[151] | 0.00[152] | -0.16[153] | 0.58[154] |
23 | AP1S2 | AP-1 complex subunit sigma-2 | [155] | -1.49[156] | -0.69[157] | -1.92[158] | 0.18[159] | 0.23[160] | -0.03[161] |
24 | AP1G2 | AP-1 complex subunit gamma-like 2 | [162] | 2.70[163] | 2.11[164] | 0.41[165] | 0.01[166] | 1.11[167] | 1.24[168] |
25 | AP4B1 | AP-4 complex subunit beta-1 | [169] | -0.28[170] | 0.20[171] | -0.32[172] | 0.27[173] | 0.80[174] | 0.66[175] |
26 | AP1S3 | AP-1 complex subunit sigma-3 | [176] | 1.86[177] | 1.63[178] | -0.51[179] | 0.42[180] | 0.62[181] | -0.54[182] |
27 | AP1M2 | AP-1 complex subunit mu-2 | [183] | 1.90[184] | 2.74[185] | 4.03[186] | 0.37[187] | 0.06[188] | -1.84[189] |
28 | AP4M1 | AP-4 complex subunit mu-1 | [190] | 0.96[191] | 1.26[192] | 1.47[193] | 0.84[194] | 1.12[195] | 0.19[196] |
29 | AP4S1 | AP-4 complex subunit sigma-1 | [197] | 1.63[198] | 0.39[199] | 1.35[200] | 0.58[201] | 0.64[202] | 0.82[203] |
30 | AP4E1 | AP-4 complex subunit epsilon-1 | [204] | 1.74[205] | 2.77[206] | 2.38[207] | 3.16[208] | 3.33[209] | 2.85[210] |
31 | ARRB1 | Beta-arrestin-1 | [211] | 4.14[212] | 4.09[213] | 3.34[214] | 2.62[215] | 2.46[216] | 4.04[217] |
32 | DNAJC6 | Putative tyrosine-protein phosphatase auxilin | [218] | 2.38[219] | 3.44[220] | 1.50[221] | 5.01[222] | 2.25[223] | 1.07[224] |
33 | SH3GL2 | Endophilin-A1 | [225] | -1.70[226] | [227] | -4.39[228] | 1.48[229] | 0.29[230] | 0.95[231] |
34 | CLVS2 | Clavesin-2 | [232] | [233] | [234] | [235] | [236] | 2.39[237] | 1.87[238] |
35 | CLVS1 | Clavesin-1 | [239] | [240] | [241] | [242] | [243] | [244] | [245] |