REACTOME_LYSINE_CATABOLISM Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 PIPOX Peroxisomal sarcosine oxidase [1] -0.79[2] -0.36[3] -4.03[4] -3.94[5] -9.54[6] 0.03[7]
2 GCDH Glutaryl-CoA dehydrogenase, mitochondrial [8] -2.31[9] -1.88[10] -0.79[11] -3.64[12] -2.47[13] -1.09[14]
3 DLD Dihydrolipoyl dehydrogenase, mitochondrial [15] -0.34[16] -0.02[17] 0.37[18] 0.84[19] 0.33[20] -0.22[21]
4 DLST Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial 1.25[22] 1.37[23] 0.85[24] 1.42[25] 1.55[26] -0.87[27]
5 ALDH7A1 Alpha-aminoadipic semialdehyde dehydrogenase [28] 1.45[29] 1.00[30] 1.34[31] 1.05[32] 1.43[33] -0.02[34]
6 OGDH 2-oxoglutarate dehydrogenase, mitochondrial [35] 1.54[36] 0.54[37] 1.99[38] 2.16[39] 2.11[40] 0.97[41]
7 AADAT Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial [42] -1.07[43] -1.24[44] -2.42[45] -1.90[46] -1.48[47] -0.09[48]
8 AASS Alpha-aminoadipic semialdehyde synthase, mitochondrial [49] -1.16[50] -1.17[51] 1.42[52] -1.64[53] 0.47[54] 2.54[55]
9 CRYM Ketimine reductase mu-crystallin [56] -2.33[57] -2.07[58] -0.55[59] -3.99[60] -5.96[61] -1.97[62]
10 SLC25A21 Mitochondrial 2-oxodicarboxylate carrier [63] -0.20[64] -5.59[65] 0.23[66] 3.11[67] -1.00[68] -1.87[69]
11 HYKK Hydroxylysine kinase [70] [71] [72] [73] [74] [75] [76]
12 PHYKPL 5-phosphohydroxy-L-lysine phospho-lyase [77] [78] [79] [80] [81] [82] [83]
[1]
ref_hepatocyte PIPOX
Mean 71.5
Standard deviation 74
Values 48 4.4 6.6 1.3e+02 1.7e+02
[2]
HepG2 PIPOX
Mean 52.9
Standard deviation 2.8
Values 55 51
[3]
HepG2.C3A PIPOX
Mean 82.4
Standard deviation 10
Values 90 75
[4]
HuH.7 PIPOX
Mean 4.25
Standard deviation 1.4
Values 3.1 5.9 3.8
[5]
SNU475 PIPOX
Mean 3.94
Standard deviation 2.9
Values 6 1.9
[6]
THLE PIPOX
Mean 0.0902
Standard deviation 0.015
Values 0.1 0.08
[7]
liver PIPOX
Mean 129
Standard deviation 83
Values 2.4e+02 59 1.4e+02 77
[8]
ref_hepatocyte GCDH
Mean 35.5
Standard deviation 31
Values 27 14 4.7 49 82
[9]
HepG2 GCDH
Mean 9.16
Standard deviation 0.58
Values 8.7 9.6
[10]
HepG2.C3A GCDH
Mean 14.3
Standard deviation 0.91
Values 15 14
[11]
HuH.7 GCDH
Mean 20
Standard deviation 9.2
Values 23 9.5 27
[12]
SNU475 GCDH
Mean 2.41
Standard deviation 0.62
Values 2.8 2
[13]
THLE GCDH
Mean 6.01
Standard deviation 1
Values 5.3 6.7
[14]
liver GCDH
Mean 29.4
Standard deviation 20
Values 56 11 34 16
[15]
ref_hepatocyte DLD
Mean 31.7
Standard deviation 25
Values 39 73 13 16 19
[16]
HepG2 DLD
Mean 31.9
Standard deviation 11
Values 24 39
[17]
HepG2.C3A DLD
Mean 46.4
Standard deviation 13
Values 37 56
[18]
HuH.7 DLD
Mean 39.8
Standard deviation 5.6
Values 44 33 43
[19]
SNU475 DLD
Mean 48.2
Standard deviation 1.7
Values 49 47
[20]
THLE DLD
Mean 37.3
Standard deviation 2.8
Values 35 39
[21]
liver DLD
Mean 47.9
Standard deviation 25
Values 56 37 79 20
[22]
ref_hepatocyte DLST
Mean 19.4
Standard deviation 4.5
Values 12 20 24 22 19
[23]
HepG2 DLST
Mean 58.7
Standard deviation 1.6
Values 60 58
[24]
HepG2.C3A DLST
Mean 74.5
Standard deviation 3.3
Values 77 72
[25]
HuH.7 DLST
Mean 34.1
Standard deviation 5.6
Values 36 28 39
[26]
SNU475 DLST
Mean 43.8
Standard deviation 3.5
Values 46 41
[27]
THLE DLST
Mean 53.2
Standard deviation 2.1
Values 52 55
[28]
liver DLST
Mean 18.7
Standard deviation 14
Values 6.4 33 6.7 28
[29]
ref_hepatocyte ALDH7A1
Mean 17.3
Standard deviation 15
Values 24 6.2 1 16 39
[30]
HepG2 ALDH7A1
Mean 60.1
Standard deviation 16
Values 49 72
[31]
HepG2.C3A ALDH7A1
Mean 51.1
Standard deviation 14
Values 41 61
[32]
HuH.7 ALDH7A1
Mean 42.6
Standard deviation 10
Values 48 31 49
[33]
SNU475 ALDH7A1
Mean 30.3
Standard deviation 10
Values 38 23
[34]
THLE ALDH7A1
Mean 43.7
Standard deviation 3.2
Values 41 46
[35]
liver ALDH7A1
Mean 30
Standard deviation 18
Values 50 17 40 14
[36]
ref_hepatocyte OGDH
Mean 9.59
Standard deviation 2.6
Values 6.1 11 12 11 7.8
[37]
HepG2 OGDH
Mean 35.5
Standard deviation 0.48
Values 35 36
[38]
HepG2.C3A OGDH
Mean 20.6
Standard deviation 2.9
Values 23 19
[39]
HuH.7 OGDH
Mean 37
Standard deviation 11
Values 47 26 38
[40]
SNU475 OGDH
Mean 36.2
Standard deviation 8.1
Values 42 31
[41]
THLE OGDH
Mean 38.9
Standard deviation 6
Values 35 43
[42]
liver OGDH
Mean 33.2
Standard deviation 11
Values 21 41 26 45
[43]
ref_hepatocyte AADAT
Mean 6.3
Standard deviation 9.1
Values 1.3 1.3 0.67 6.3 22
[44]
HepG2 AADAT
Mean 3.81
Standard deviation 2.5
Values 2 5.6
[45]
HepG2.C3A AADAT
Mean 3.96
Standard deviation 1.1
Values 3.2 4.7
[46]
HuH.7 AADAT
Mean 1.15
Standard deviation 0.46
Values 1.4 0.62 1.5
[47]
SNU475 AADAT
Mean 1.43
Standard deviation 0.11
Values 1.5 1.3
[48]
THLE AADAT
Mean 2.12
Standard deviation 0.11
Values 2 2.2
[49]
liver AADAT
Mean 10.5
Standard deviation 4.6
Values 16 7.2 13 6
[50]
ref_hepatocyte AASS
Mean 5.29
Standard deviation 3.8
Values 6.2 1.7 1.7 6.1 11
[51]
HepG2 AASS
Mean 3.02
Standard deviation 1.4
Values 2 4
[52]
HepG2.C3A AASS
Mean 3.49
Standard deviation 0.25
Values 3.7 3.3
[53]
HuH.7 AASS
Mean 13.8
Standard deviation 1.4
Values 14 15 12
[54]
SNU475 AASS
Mean 1.44
Standard deviation 0.25
Values 1.6 1.3
[55]
THLE AASS
Mean 6.86
Standard deviation 0.92
Values 7.5 6.2
[56]
liver AASS
Mean 54.2
Standard deviation 15
Values 57 56 34 69
[57]
ref_hepatocyte CRYM
Mean 4.3
Standard deviation 1.8
Values 4.1 4 1.7 6.5 5.2
[58]
HepG2 CRYM
Mean 1.09
Standard deviation 0.3
Values 1.3 0.88
[59]
HepG2.C3A CRYM
Mean 1.51
Standard deviation 0.18
Values 1.6 1.4
[60]
HuH.7 CRYM
Mean 2.86
Standard deviation 0.63
Values 2.2 3 3.4
[61]
SNU475 CRYM
Mean 0.229
Standard deviation 0.17
Values 0.35 0.11
[62]
THLE CRYM
Mean 0.0645
Standard deviation 0.00088
Values 0.065 0.064
[63]
liver CRYM
Mean 1.93
Standard deviation 1.1
Values 1.2 1.7 3.5 1.3
[64]
ref_hepatocyte SLC25A21
Mean 0.332
Standard deviation 0.26
Values 0.33 0 0.53 0.16 0.64
[65]
HepG2 SLC25A21
Mean 0.37
Standard deviation 0.27
Values 0.18 0.56
[66]
HepG2.C3A SLC25A21
Mean 0.0102
Standard deviation 0.00071
Values 0.0097 0.011
[67]
HuH.7 SLC25A21
Mean 0.381
Standard deviation 0.13
Values 0.49 0.24 0.41
[68]
SNU475 SLC25A21
Mean 2.43
Standard deviation 0.12
Values 2.5 2.3
[69]
THLE SLC25A21
Mean 0.156
Standard deviation 0.028
Values 0.14 0.18
[70]
liver SLC25A21
Mean 0.16
Standard deviation 0.044
Values 0.16 0.1 0.21 0.17
[71]
ref_hepatocyte HYKK
Missing
[72]
HepG2 HYKK
Missing
[73]
HepG2.C3A HYKK
Missing
[74]
HuH.7 HYKK
Missing
[75]
SNU475 HYKK
Missing
[76]
THLE HYKK
Missing
[77]
liver HYKK
Missing
[78]
ref_hepatocyte PHYKPL
Missing
[79]
HepG2 PHYKPL
Missing
[80]
HepG2.C3A PHYKPL
Missing
[81]
HuH.7 PHYKPL
Missing
[82]
SNU475 PHYKPL
Missing
[83]
THLE PHYKPL
Missing
[84]
liver PHYKPL
Missing