REACTOME_LOSS_OF_FUNCTION_OF_SMAD2_3_IN_CANCER Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 TGFBR2 TGF-beta receptor type-2 [1] 0.52[2] 0.36[3] 0.36[4] -0.77[5] 0.24[6] -0.11[7]
2 SMAD3 Mothers against decapentaplegic homolog 3 [8] -0.37[9] -0.60[10] -0.03[11] -0.03[12] 0.14[13] -1.41[14]
3 TGFBR1 TGF-beta receptor type-1 [15] -1.97[16] -1.37[17] -1.53[18] -1.49[19] -1.09[20] -0.28[21]
4 SMAD4 Mothers against decapentaplegic homolog 4 [22] -0.91[23] 0.10[24] 0.40[25] 0.08[26] -0.27[27] 1.17[28]
5 SMAD2 Mothers against decapentaplegic homolog 2 [29] -0.28[30] 0.35[31] 0.19[32] 0.55[33] 0.03[34] 0.95[35]
6 TGFB1 Transforming growth factor beta-1 [36] 1.17[37] 0.51[38] -1.90[39] 2.01[40] 0.52[41] -2.85[42]
7 ZFYVE9 Zinc finger FYVE domain-containing protein 9 [43] -0.66[44] -0.05[45] 0.25[46] -0.23[47] -0.49[48] 0.59[49]
[1]
ref_hepatocyte TGFBR2
Mean 11.1
Standard deviation 9.7
Values 26 15 6.4 4.2 3.5
[2]
HepG2 TGFBR2
Mean 172
Standard deviation 10
Values 1.7e+02 1.8e+02
[3]
HepG2.C3A TGFBR2
Mean 106
Standard deviation 5.8
Values 1.1e+02 1e+02
[4]
HuH.7 TGFBR2
Mean 80.1
Standard deviation 11
Values 92 71 77
[5]
SNU475 TGFBR2
Mean 42.5
Standard deviation 18
Values 29 55
[6]
THLE TGFBR2
Mean 157
Standard deviation 23
Values 1.4e+02 1.7e+02
[7]
liver TGFBR2
Mean 44.6
Standard deviation 11
Values 31 51 40 57
[8]
ref_hepatocyte SMAD3
Mean 5.99
Standard deviation 4.6
Values 4.8 8.4 13 1.9 2.2
[9]
HepG2 SMAD3
Mean 50.4
Standard deviation 14
Values 60 40
[10]
HepG2.C3A SMAD3
Mean 29.5
Standard deviation 11
Values 37 22
[11]
HuH.7 SMAD3
Mean 33.2
Standard deviation 6.9
Values 31 41 28
[12]
SNU475 SMAD3
Mean 38.2
Standard deviation 2.7
Values 40 36
[13]
THLE SMAD3
Mean 78.9
Standard deviation 8.4
Values 73 85
[14]
liver SMAD3
Mean 9.85
Standard deviation 3
Values 12 7.4 7.1 13
[15]
ref_hepatocyte TGFBR1
Mean 4.72
Standard deviation 3.6
Values 4.2 11 3.6 1.8 3.1
[16]
HepG2 TGFBR1
Mean 13.1
Standard deviation 3.3
Values 11 15
[17]
HepG2.C3A TGFBR1
Mean 13.6
Standard deviation 0.22
Values 13 14
[18]
HuH.7 TGFBR1
Mean 9.25
Standard deviation 2.6
Values 8.3 12 7.2
[19]
SNU475 TGFBR1
Mean 11
Standard deviation 1.8
Values 9.7 12
[20]
THLE TGFBR1
Mean 26.5
Standard deviation 5.3
Values 30 23
[21]
liver TGFBR1
Mean 16.9
Standard deviation 7.4
Values 8.6 25 13 20
[22]
ref_hepatocyte SMAD4
Mean 3.16
Standard deviation 0.71
Values 2.9 2.8 4.2 2.4 3.4
[23]
HepG2 SMAD4
Mean 18.3
Standard deviation 3.2
Values 16 21
[24]
HepG2.C3A SMAD4
Mean 25.2
Standard deviation 3
Values 27 23
[25]
HuH.7 SMAD4
Mean 23.6
Standard deviation 3.4
Values 24 27 20
[26]
SNU475 SMAD4
Mean 21.8
Standard deviation 2.7
Values 24 20
[27]
THLE SMAD4
Mean 31.4
Standard deviation 1.4
Values 30 32
[28]
liver SMAD4
Mean 31
Standard deviation 13
Values 23 40 16 44
[29]
ref_hepatocyte SMAD2
Mean 2.54
Standard deviation 1.2
Values 4.5 2.8 1.9 1.9 1.6
[30]
HepG2 SMAD2
Mean 22.7
Standard deviation 2.3
Values 21 24
[31]
HepG2.C3A SMAD2
Mean 24.2
Standard deviation 1.1
Values 25 23
[32]
HuH.7 SMAD2
Mean 16.4
Standard deviation 1.6
Values 17 18 15
[33]
SNU475 SMAD2
Mean 24.3
Standard deviation 3.3
Values 27 22
[34]
THLE SMAD2
Mean 31
Standard deviation 0.65
Values 31 32
[35]
liver SMAD2
Mean 21.4
Standard deviation 6.7
Values 17 29 15 25
[36]
ref_hepatocyte TGFB1
Mean 2.22
Standard deviation 1.8
Values 5.3 1.3 0.92 1.3 2.3
[37]
HepG2 TGFB1
Mean 54.4
Standard deviation 32
Values 77 32
[38]
HepG2.C3A TGFB1
Mean 23.6
Standard deviation 8.3
Values 29 18
[39]
HuH.7 TGFB1
Mean 3.37
Standard deviation 1.4
Values 4.5 1.8 3.7
[40]
SNU475 TGFB1
Mean 58.3
Standard deviation 7.8
Values 64 53
[41]
THLE TGFB1
Mean 38.3
Standard deviation 9.8
Values 31 45
[42]
liver TGFB1
Mean 1.34
Standard deviation 0.71
Values 1.1 1.4 0.62 2.3
[43]
ref_hepatocyte ZFYVE9
Mean 1.96
Standard deviation 0.58
Values 3 1.6 1.8 1.5 1.9
[44]
HepG2 ZFYVE9
Mean 13.5
Standard deviation 4
Values 11 16
[45]
HepG2.C3A ZFYVE9
Mean 14.2
Standard deviation 1.5
Values 13 15
[46]
HuH.7 ZFYVE9
Mean 13.2
Standard deviation 2.5
Values 16 13 11
[47]
SNU475 ZFYVE9
Mean 10.9
Standard deviation 1.4
Values 12 10
[48]
THLE ZFYVE9
Mean 16.8
Standard deviation 0.22
Values 17 17
[49]
liver ZFYVE9
Mean 12.8
Standard deviation 11
Values 4.9 25 1.8 20