REACTOME_LIGAND_RECEPTOR_INTERACTIONS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 SHH Sonic hedgehog protein [1] -1.40[2] -1.24[3] -2.42[4] -9.80[5] -9.76[6] -2.05[7]
2 CDON Cell adhesion molecule-related/down-regulated by oncogenes [8] 1.32[9] 1.08[10] -0.37[11] 1.65[12] 0.22[13] 0.11[14]
3 PTCH1 Protein patched homolog 1 [15] 0.86[16] 1.40[17] 1.51[18] 0.70[19] 0.22[20] 0.67[21]
4 IHH Indian hedgehog protein [22] -0.72[23] -2.37[24] 2.18[25] -6.92[26] -7.60[27] -2.08[28]
5 GAS1 Growth arrest-specific protein 1 [29] -6.39[30] [31] -6.85[32] -1.65[33] 3.57[34] 0.00[35]
6 BOC Brother of CDO [36] -0.26[37] [38] -3.15[39] 5.14[40] 3.10[41] 2.38[42]
7 HHIP Hedgehog-interacting protein [43] [44] [45] [46] [47] [48] [49]
8 DHH Desert hedgehog protein [50] [51] [52] [53] [54] [55] [56]
[1]
ref_hepatocyte SHH
Mean 1.15
Standard deviation 1
Values 0.23 0 2.5 1.4 1.6
[2]
HepG2 SHH
Mean 3.31
Standard deviation 2.1
Values 4.8 1.8
[3]
HepG2.C3A SHH
Mean 2.66
Standard deviation 0.92
Values 3.3 2
[4]
HuH.7 SHH
Mean 2.69
Standard deviation 0.5
Values 2.5 3.3 2.3
[5]
SNU475 SHH
Mean 0.0146
Standard deviation 0.00091
Values 0.014 0.015
[6]
THLE SHH
Mean 0.0148
Standard deviation 0.021
Values 0.03 0
[7]
liver SHH
Mean 1.79
Standard deviation 2.1
Values 0.12 2.9 0 4.1
[8]
ref_hepatocyte CDON
Mean 0.452
Standard deviation 0.47
Values 1.3 0.26 0.36 0.16 0.19
[9]
HepG2 CDON
Mean 8.54
Standard deviation 0.057
Values 8.5 8.6
[10]
HepG2.C3A CDON
Mean 5.21
Standard deviation 0.24
Values 5.4 5
[11]
HuH.7 CDON
Mean 4.38
Standard deviation 1.8
Values 4 6.4 2.8
[12]
SNU475 CDON
Mean 16
Standard deviation 6.6
Values 21 11
[13]
THLE CDON
Mean 5.88
Standard deviation 0.097
Values 5.8 6
[14]
liver CDON
Mean 3.14
Standard deviation 2.4
Values 1.6 3.4 1.1 6.5
[15]
ref_hepatocyte PTCH1
Mean 0.253
Standard deviation 0.18
Values 0.17 0.14 0.51 0.078 0.37
[16]
HepG2 PTCH1
Mean 3.48
Standard deviation 2.7
Values 5.4 1.6
[17]
HepG2.C3A PTCH1
Mean 3.66
Standard deviation 0.94
Values 4.3 3
[18]
HuH.7 PTCH1
Mean 9.01
Standard deviation 1
Values 10 9 7.9
[19]
SNU475 PTCH1
Mean 4.67
Standard deviation 0.47
Values 4.3 5
[20]
THLE PTCH1
Mean 3.31
Standard deviation 0.69
Values 2.8 3.8
[21]
liver PTCH1
Mean 2.58
Standard deviation 0.39
Values 2.9 2 2.8 2.6
[22]
ref_hepatocyte IHH
Mean 0.19
Standard deviation 0.27
Values 0 0.054 0 0.28 0.62
[23]
HepG2 IHH
Mean 0.871
Standard deviation 0.39
Values 0.6 1.1
[24]
HepG2.C3A IHH
Mean 0.201
Standard deviation 0.05
Values 0.17 0.24
[25]
HuH.7 IHH
Mean 10.8
Standard deviation 0.98
Values 9.7 11 11
[26]
SNU475 IHH
Mean 0.0177
Standard deviation 0.025
Values 0 0.035
[27]
THLE IHH
Mean 0.0109
Standard deviation 0.0071
Values 0.0059 0.016
[28]
liver IHH
Mean 0.288
Standard deviation 0.17
Values 0.49 0.17 0.13 0.36
[29]
ref_hepatocyte GAS1
Mean 0.0949
Standard deviation 0.1
Values 0 0 0.13 0.095 0.25
[30]
HepG2 GAS1
Mean 0.0086
Standard deviation 0.012
Values 0.017 0
[31]
HepG2.C3A GAS1
Mean 0
Standard deviation 0
Values 0 0
[32]
HuH.7 GAS1
Mean 0.0103
Standard deviation 0.013
Values 0.025 0.0064 0
[33]
SNU475 GAS1
Mean 0.343
Standard deviation 0.21
Values 0.19 0.49
[34]
THLE GAS1
Mean 12.6
Standard deviation 3.4
Values 10 15
[35]
liver GAS1
Mean 0.608
Standard deviation 0.22
Values 0.63 0.83 0.31 0.66
[36]
ref_hepatocyte BOC
Mean 0.00813
Standard deviation 0.018
Values 0 0 0 0 0.041
[37]
HepG2 BOC
Mean 0.0516
Standard deviation 0.049
Values 0.086 0.017
[38]
HepG2.C3A BOC
Mean 0
Standard deviation 0
Values 0 0
[39]
HuH.7 BOC
Mean 0.0115
Standard deviation 0.015
Values 0 0.0064 0.028
[40]
SNU475 BOC
Mean 3.24
Standard deviation 0.38
Values 3.5 3
[41]
THLE BOC
Mean 0.781
Standard deviation 0.13
Values 0.88 0.69
[42]
liver BOC
Mean 0.271
Standard deviation 0.4
Values 0.024 0.071 0.13 0.86
[43]
ref_hepatocyte HHIP
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[44]
HepG2 HHIP
Mean 0.00788
Standard deviation 0.0051
Values 0.011 0.0043
[45]
HepG2.C3A HHIP
Mean 0
Standard deviation 0
Values 0 0
[46]
HuH.7 HHIP
Mean 0.00586
Standard deviation 0.0051
Values 0.0082 0 0.0094
[47]
SNU475 HHIP
Mean 0.035
Standard deviation 0.036
Values 0.0093 0.061
[48]
THLE HHIP
Mean 1.37
Standard deviation 0.85
Values 0.77 2
[49]
liver HHIP
Mean 5.1
Standard deviation 1.4
Values 3.8 6.3 6.4 4
[50]
ref_hepatocyte DHH
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[51]
HepG2 DHH
Mean 0.00716
Standard deviation 0.002
Values 0.0057 0.0086
[52]
HepG2.C3A DHH
Mean 0.00972
Standard deviation 0.014
Values 0.019 0
[53]
HuH.7 DHH
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[54]
SNU475 DHH
Mean 0.00696
Standard deviation 0.0098
Values 0.014 0
[55]
THLE DHH
Mean 0.0225
Standard deviation 0.0017
Values 0.024 0.021
[56]
liver DHH
Mean 0.03
Standard deviation 0.051
Values 0 0.014 0 0.11