REACTOME_LGI_ADAM_INTERACTIONS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 STX1A Syntaxin-1A [1] -1.00[2] -1.97[3] -4.26[4] -0.76[5] -1.43[6] -1.80[7]
2 DLG4 Disks large homolog 4 [8] 0.84[9] 0.19[10] -1.86[11] -1.40[12] 1.14[13] 1.06[14]
3 STX1B Syntaxin-1B [15] -1.46[16] -0.34[17] -4.34[18] -2.58[19] -1.69[20] 0.79[21]
4 CACNG8 Voltage-dependent calcium channel gamma-8 subunit [22] -0.91[23] -0.73[24] -2.87[25] -1.91[26] 1.42[27] -1.08[28]
5 ADAM22 Disintegrin and metalloproteinase domain-containing protein 22 [29] 1.01[30] 2.01[31] 0.49[32] -4.13[33] -0.31[34] 0.79[35]
6 LGI4 Leucine-rich repeat LGI family member 4 [36] -2.05[37] -0.90[38] 0.27[39] -7.79[40] -5.66[41] 0.08[42]
7 LGI1 Leucine-rich glioma-inactivated protein 1 [43] -6.63[44] -7.64[45] [46] -9.09[47] [48] 0.05[49]
8 CACNG4 Voltage-dependent calcium channel gamma-4 subunit [50] 2.86[51] 3.29[52] -5.79[53] 0.38[54] -6.07[55] -1.86[56]
9 ADAM23 Disintegrin and metalloproteinase domain-containing protein 23 [57] -0.22[58] -2.69[59] 5.85[60] 5.59[61] 3.23[62] 0.29[63]
10 ADAM11 Disintegrin and metalloproteinase domain-containing protein 11 [64] 4.55[65] 3.30[66] 1.77[67] 0.82[68] 2.90[69] 1.59[70]
11 CACNG3 Voltage-dependent calcium channel gamma-3 subunit [71] [72] [73] [74] [75] [76] [77]
12 CACNG2 Voltage-dependent calcium channel gamma-2 subunit [78] [79] [80] [81] [82] [83] [84]
13 LGI3 Leucine-rich repeat LGI family member 3 [85] [86] [87] [88] [89] [90] [91]
14 LGI2 Leucine-rich repeat LGI family member 2 [92] [93] [94] [95] [96] [97] [98]
[1]
ref_hepatocyte STX1A
Mean 0.672
Standard deviation 0.98
Values 0.23 0.39 2.4 0.095 0.24
[2]
HepG2 STX1A
Mean 2.85
Standard deviation 0.85
Values 3.4 2.2
[3]
HepG2.C3A STX1A
Mean 2.48
Standard deviation 0.71
Values 3 2
[4]
HuH.7 STX1A
Mean 0.845
Standard deviation 0.25
Values 0.57 0.91 1.1
[5]
SNU475 STX1A
Mean 7.45
Standard deviation 3.6
Values 4.9 10
[6]
THLE STX1A
Mean 4.19
Standard deviation 1.3
Values 5.1 3.3
[7]
liver STX1A
Mean 0.426
Standard deviation 0.18
Values 0.35 0.31 0.69 0.34
[8]
ref_hepatocyte DLG4
Mean 0.259
Standard deviation 0.21
Values 0.17 0 0.16 0.45 0.51
[9]
HepG2 DLG4
Mean 3.93
Standard deviation 2.2
Values 5.5 2.3
[10]
HepG2.C3A DLG4
Mean 4.27
Standard deviation 0.27
Values 4.5 4.1
[11]
HuH.7 DLG4
Mean 1.73
Standard deviation 0.71
Values 1.3 2.5 1.3
[12]
SNU475 DLG4
Mean 1.85
Standard deviation 0.71
Values 1.3 2.4
[13]
THLE DLG4
Mean 9.6
Standard deviation 0.94
Values 10 8.9
[14]
liver DLG4
Mean 1.19
Standard deviation 1.3
Values 0.26 1.2 0.28 3
[15]
ref_hepatocyte STX1B
Mean 0.198
Standard deviation 0.14
Values 0.28 0 0.11 0.24 0.37
[16]
HepG2 STX1B
Mean 0.607
Standard deviation 0.42
Values 0.31 0.91
[17]
HepG2.C3A STX1B
Mean 2.27
Standard deviation 0.33
Values 2 2.5
[18]
HuH.7 STX1B
Mean 0.236
Standard deviation 0.063
Values 0.16 0.26 0.28
[19]
SNU475 STX1B
Mean 0.621
Standard deviation 0.27
Values 0.81 0.43
[20]
THLE STX1B
Mean 1.03
Standard deviation 0.077
Values 1.1 0.97
[21]
liver STX1B
Mean 0.753
Standard deviation 0.22
Values 0.45 0.76 0.98 0.83
[22]
ref_hepatocyte CACNG8
Mean 0.161
Standard deviation 0.16
Values 0.38 0.26 0 0.043 0.12
[23]
HepG2 CACNG8
Mean 0.724
Standard deviation 0.068
Values 0.68 0.77
[24]
HepG2.C3A CACNG8
Mean 1.4
Standard deviation 0.39
Values 1.1 1.7
[25]
HuH.7 CACNG8
Mean 0.534
Standard deviation 0.1
Values 0.42 0.56 0.62
[26]
SNU475 CACNG8
Mean 0.804
Standard deviation 0.0025
Values 0.8 0.81
[27]
THLE CACNG8
Mean 7.26
Standard deviation 0.26
Values 7.4 7.1
[28]
liver CACNG8
Mean 0.169
Standard deviation 0.13
Values 0.024 0.26 0.1 0.29
[29]
ref_hepatocyte ADAM22
Mean 0.117
Standard deviation 0.2
Values 0.47 0 0.11 0 0.0081
[30]
HepG2 ADAM22
Mean 2
Standard deviation 0.82
Values 1.4 2.6
[31]
HepG2.C3A ADAM22
Mean 6.8
Standard deviation 0.16
Values 6.7 6.9
[32]
HuH.7 ADAM22
Mean 3.97
Standard deviation 0.97
Values 3.9 5 3
[33]
SNU475 ADAM22
Mean 0.125
Standard deviation 0.059
Values 0.083 0.17
[34]
THLE ADAM22
Mean 1.59
Standard deviation 0.36
Values 1.8 1.3
[35]
liver ADAM22
Mean 0.448
Standard deviation 0.32
Values 0.16 0.46 0.28 0.89
[36]
ref_hepatocyte LGI4
Mean 0.114
Standard deviation 0.16
Values 0 0 0 0.29 0.28
[37]
HepG2 LGI4
Mean 0.233
Standard deviation 0.17
Values 0.35 0.12
[38]
HepG2.C3A LGI4
Mean 0.881
Standard deviation 0.34
Values 1.1 0.64
[39]
HuH.7 LGI4
Mean 3.32
Standard deviation 5.1
Values 0.29 9.2 0.49
[40]
SNU475 LGI4
Mean 0.00971
Standard deviation 0.00061
Values 0.0093 0.01
[41]
THLE LGI4
Mean 0.0379
Standard deviation 0.038
Values 0.065 0.011
[42]
liver LGI4
Mean 0.265
Standard deviation 0.06
Values 0.19 0.29 0.26 0.33
[43]
ref_hepatocyte LGI1
Mean 0.067
Standard deviation 0.092
Values 0 0 0 0.17 0.16
[44]
HepG2 LGI1
Mean 0.00573
Standard deviation 0.0081
Values 0.011 0
[45]
HepG2.C3A LGI1
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[46]
HuH.7 LGI1
Mean 0
Standard deviation 0
Values 0 0 0
[47]
SNU475 LGI1
Mean 0.00232
Standard deviation 0.0033
Values 0.0046 0
[48]
THLE LGI1
Mean 0
Standard deviation 0
Values 0 0
[49]
liver LGI1
Mean 0.153
Standard deviation 0.18
Values 0.42 0.071 0.077 0.04
[50]
ref_hepatocyte CACNG4
Mean 0.0344
Standard deviation 0.077
Values 0.17 0 0 0 0
[51]
HepG2 CACNG4
Mean 2.12
Standard deviation 0.19
Values 2.3 2
[52]
HepG2.C3A CACNG4
Mean 4.88
Standard deviation 0.63
Values 4.4 5.3
[53]
HuH.7 CACNG4
Mean 0.015
Standard deviation 0.026
Values 0 0.045 0
[54]
SNU475 CACNG4
Mean 0.84
Standard deviation 0.39
Values 1.1 0.57
[55]
THLE CACNG4
Mean 0.00858
Standard deviation 0.0046
Values 0.012 0.0053
[56]
liver CACNG4
Mean 0.0209
Standard deviation 0.027
Values 0 0.057 0 0.026
[57]
ref_hepatocyte ADAM23
Mean 0.0204
Standard deviation 0.034
Values 0 0.078 0 0 0.024
[58]
HepG2 ADAM23
Mean 0.149
Standard deviation 0.11
Values 0.23 0.069
[59]
HepG2.C3A ADAM23
Mean 0.0458
Standard deviation 0.004
Values 0.049 0.043
[60]
HuH.7 ADAM23
Mean 28.4
Standard deviation 2.1
Values 29 30 26
[61]
SNU475 ADAM23
Mean 18.5
Standard deviation 6.2
Values 23 14
[62]
THLE ADAM23
Mean 3.21
Standard deviation 1.4
Values 2.2 4.2
[63]
liver ADAM23
Mean 0.055
Standard deviation 0.064
Values 0 0.11 0 0.11
[64]
ref_hepatocyte ADAM11
Mean 0.00565
Standard deviation 0.013
Values 0.028 0 0 0 0
[65]
HepG2 ADAM11
Mean 1.12
Standard deviation 0.47
Values 0.79 1.5
[66]
HepG2.C3A ADAM11
Mean 0.803
Standard deviation 0.21
Values 0.65 0.95
[67]
HuH.7 ADAM11
Mean 0.465
Standard deviation 0.053
Values 0.52 0.41 0.47
[68]
SNU475 ADAM11
Mean 0.187
Standard deviation 0.022
Values 0.17 0.2
[69]
THLE ADAM11
Mean 0.708
Standard deviation 0.053
Values 0.75 0.67
[70]
liver ADAM11
Mean 0.0375
Standard deviation 0.043
Values 0.024 0.1 0 0.026
[71]
ref_hepatocyte CACNG3
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[72]
HepG2 CACNG3
Missing
[73]
HepG2.C3A CACNG3
Missing
[74]
HuH.7 CACNG3
Missing
[75]
SNU475 CACNG3
Missing
[76]
THLE CACNG3
Missing
[77]
liver CACNG3
Missing
[78]
ref_hepatocyte CACNG2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[79]
HepG2 CACNG2
Mean 0.00287
Standard deviation 0.0041
Values 0.0057 0
[80]
HepG2.C3A CACNG2
Mean 0
Standard deviation 0
Values 0 0
[81]
HuH.7 CACNG2
Mean 0
Standard deviation 0
Values 0 0 0
[82]
SNU475 CACNG2
Mean 0
Standard deviation 0
Values 0 0
[83]
THLE CACNG2
Mean 0
Standard deviation 0
Values 0 0
[84]
liver CACNG2
Mean 0.0275
Standard deviation 0.032
Values 0 0.057 0 0.053
[85]
ref_hepatocyte LGI3
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[86]
HepG2 LGI3
Mean 0.229
Standard deviation 0.23
Values 0.39 0.069
[87]
HepG2.C3A LGI3
Mean 0.0317
Standard deviation 0.031
Values 0.0097 0.054
[88]
HuH.7 LGI3
Mean 0.0105
Standard deviation 0.0096
Values 0 0.013 0.019
[89]
SNU475 LGI3
Mean 0.525
Standard deviation 0.17
Values 0.64 0.41
[90]
THLE LGI3
Mean 0.0204
Standard deviation 0.021
Values 0.035 0.0053
[91]
liver LGI3
Mean 0.0252
Standard deviation 0.022
Values 0.047 0.014 0 0.04
[92]
ref_hepatocyte LGI2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[93]
HepG2 LGI2
Mean 0.00287
Standard deviation 0.0041
Values 0.0057 0
[94]
HepG2.C3A LGI2
Mean 0
Standard deviation 0
Values 0 0
[95]
HuH.7 LGI2
Mean 0.33
Standard deviation 0.24
Values 0.49 0.058 0.44
[96]
SNU475 LGI2
Mean 0.0553
Standard deviation 0.065
Values 0.0093 0.1
[97]
THLE LGI2
Mean 0.0512
Standard deviation 0.02
Values 0.065 0.037
[98]
liver LGI2
Mean 0.064
Standard deviation 0.07
Values 0 0.071 0.026 0.16