REACTOME_KILLING_MECHANISMS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 RAC1 Ras-related C3 botulinum toxin substrate 1 [1] -0.63[2] -0.83[3] 0.00[4] -0.19[5] -0.56[6] 0.07[7]
2 JUN Transcription factor AP-1 [8] -0.72[9] -2.14[10] -1.75[11] -1.91[12] -1.69[13] -0.78[14]
3 CYBA Cytochrome b-245 light chain [15] 1.25[16] 1.42[17] 0.44[18] 0.01[19] -0.45[20] -0.38[21]
4 DVL1 Segment polarity protein dishevelled homolog DVL-1 [22] 0.57[23] 1.15[24] 0.15[25] -0.13[26] -0.45[27] 0.27[28]
5 MAPK8 Mitogen-activated protein kinase 8 [29] -1.68[30] -0.14[31] -1.15[32] -1.11[33] -1.60[34] 0.52[35]
6 DVL3 Segment polarity protein dishevelled homolog DVL-3 [36] 1.25[37] 1.60[38] 1.11[39] 1.26[40] 0.99[41] 1.34[42]
7 DVL2 Segment polarity protein dishevelled homolog DVL-2 [43] 1.88[44] 1.76[45] 2.87[46] 2.02[47] 1.31[48] 1.04[49]
8 NOXA1 NADPH oxidase activator 1 [50] -2.60[51] -0.70[52] -1.62[53] -2.59[54] -4.16[55] 0.06[56]
9 FZD7 Frizzled-7 [57] 1.97[58] -1.94[59] 4.19[60] 4.35[61] 1.41[62] 1.05[63]
10 NOXO1 NADPH oxidase organizer 1 [64] -0.74[65] 0.70[66] -1.87[67] -2.70[68] -2.82[69] 0.31[70]
11 WNT5A Protein Wnt-5a [71] -3.43[72] -3.29[73] -2.00[74] 6.39[75] 7.61[76] 2.34[77]
12 NOX1 NADPH oxidase 1 [78] 0.12[79] -0.52[80] 4.77[81] -0.27[82] 0.76[83] 1.87[84]
[1]
ref_hepatocyte RAC1
Mean 52
Standard deviation 20
Values 28 59 81 45 47
[2]
HepG2 RAC1
Mean 87.4
Standard deviation 1.9
Values 89 86
[3]
HepG2.C3A RAC1
Mean 62
Standard deviation 7.4
Values 67 57
[4]
HuH.7 RAC1
Mean 97.2
Standard deviation 9.7
Values 1e+02 86 1e+02
[5]
SNU475 RAC1
Mean 96.5
Standard deviation 10
Values 89 1e+02
[6]
THLE RAC1
Mean 107
Standard deviation 19
Values 94 1.2e+02
[7]
liver RAC1
Mean 37.8
Standard deviation 32
Values 63 12 67 9.5
[8]
ref_hepatocyte JUN
Mean 42.9
Standard deviation 25
Values 26 30 66 73 20
[9]
HepG2 JUN
Mean 67.5
Standard deviation 36
Values 93 42
[10]
HepG2.C3A JUN
Mean 20.6
Standard deviation 11
Values 28 13
[11]
HuH.7 JUN
Mean 23.9
Standard deviation 19
Values 11 46 14
[12]
SNU475 JUN
Mean 24.2
Standard deviation 4.1
Values 21 27
[13]
THLE JUN
Mean 40.2
Standard deviation 4.7
Values 37 44
[14]
liver JUN
Mean 17.4
Standard deviation 8.4
Values 25 24 8.4 12
[15]
ref_hepatocyte CYBA
Mean 14.8
Standard deviation 11
Values 26 0 10 13 25
[16]
HepG2 CYBA
Mean 91.8
Standard deviation 21
Values 1.1e+02 77
[17]
HepG2.C3A CYBA
Mean 84.2
Standard deviation 25
Values 1e+02 67
[18]
HuH.7 CYBA
Mean 37.6
Standard deviation 8.2
Values 39 29 45
[19]
SNU475 CYBA
Mean 31.6
Standard deviation 8
Values 37 26
[20]
THLE CYBA
Mean 32.9
Standard deviation 4.2
Values 30 36
[21]
liver CYBA
Mean 7.9
Standard deviation 3.4
Values 12 5.8 9.4 4.5
[22]
ref_hepatocyte DVL1
Mean 12.4
Standard deviation 6.1
Values 7.3 18 20 9.2 7.4
[23]
HepG2 DVL1
Mean 47.7
Standard deviation 14
Values 58 38
[24]
HepG2.C3A DVL1
Mean 58.3
Standard deviation 12
Values 67 50
[25]
HuH.7 DVL1
Mean 25.7
Standard deviation 0.88
Values 26 25 26
[26]
SNU475 DVL1
Mean 23.8
Standard deviation 0.22
Values 24 24
[27]
THLE DVL1
Mean 27.3
Standard deviation 0.93
Values 27 28
[28]
liver DVL1
Mean 10.4
Standard deviation 6.8
Values 6.1 14 3.4 18
[29]
ref_hepatocyte MAPK8
Mean 7.1
Standard deviation 4.4
Values 6.5 5.6 15 3.8 4.7
[30]
HepG2 MAPK8
Mean 5.76
Standard deviation 1
Values 5.1 6.5
[31]
HepG2.C3A MAPK8
Mean 13.6
Standard deviation 4
Values 11 17
[32]
HuH.7 MAPK8
Mean 5.99
Standard deviation 0.68
Values 6.5 6.2 5.2
[33]
SNU475 MAPK8
Mean 6.98
Standard deviation 0.5
Values 7.3 6.6
[34]
THLE MAPK8
Mean 7.08
Standard deviation 1
Values 6.4 7.8
[35]
liver MAPK8
Mean 7.08
Standard deviation 1
Values 7.3 7.8 5.6 7.6
[36]
ref_hepatocyte DVL3
Mean 5.91
Standard deviation 4.4
Values 4 3 14 5.1 3.8
[37]
HepG2 DVL3
Mean 36.6
Standard deviation 1.4
Values 36 38
[38]
HepG2.C3A DVL3
Mean 37.8
Standard deviation 3.9
Values 41 35
[39]
HuH.7 DVL3
Mean 23.9
Standard deviation 1.6
Values 26 23 23
[40]
SNU475 DVL3
Mean 30
Standard deviation 4.2
Values 33 27
[41]
THLE DVL3
Mean 35.4
Standard deviation 0.44
Values 35 36
[42]
liver DVL3
Mean 10.4
Standard deviation 1.4
Values 12 9.9 8.8 11
[43]
ref_hepatocyte DVL2
Mean 2.34
Standard deviation 0.94
Values 3.3 0.77 2.7 2.5 2.4
[44]
HepG2 DVL2
Mean 22.4
Standard deviation 2.6
Values 24 21
[45]
HepG2.C3A DVL2
Mean 16.8
Standard deviation 0.55
Values 17 16
[46]
HuH.7 DVL2
Mean 31.8
Standard deviation 1.9
Values 30 34 32
[47]
SNU475 DVL2
Mean 20
Standard deviation 2.6
Values 22 18
[48]
THLE DVL2
Mean 17.6
Standard deviation 1.2
Values 17 18
[49]
liver DVL2
Mean 3.34
Standard deviation 0.75
Values 3.5 3.2 2.5 4.3
[50]
ref_hepatocyte NOXA1
Mean 1.89
Standard deviation 1.8
Values 0.22 0.24 1.3 3.9 3.9
[51]
HepG2 NOXA1
Mean 0.811
Standard deviation 0.3
Values 1 0.6
[52]
HepG2.C3A NOXA1
Mean 2.46
Standard deviation 1.3
Values 3.4 1.5
[53]
HuH.7 NOXA1
Mean 1.15
Standard deviation 0.47
Values 0.78 1.7 0.98
[54]
SNU475 NOXA1
Mean 0.661
Standard deviation 0.38
Values 0.93 0.39
[55]
THLE NOXA1
Mean 0.319
Standard deviation 0.23
Values 0.48 0.16
[56]
liver NOXA1
Mean 1.37
Standard deviation 0.56
Values 2.2 0.98 1.3 0.98
[57]
ref_hepatocyte FZD7
Mean 0.384
Standard deviation 0.68
Values 0 0 1.6 0.069 0.27
[58]
HepG2 FZD7
Mean 3.9
Standard deviation 2.2
Values 5.5 2.3
[59]
HepG2.C3A FZD7
Mean 0.211
Standard deviation 0.065
Values 0.17 0.26
[60]
HuH.7 FZD7
Mean 13.1
Standard deviation 4.3
Values 16 8.1 15
[61]
SNU475 FZD7
Mean 16.6
Standard deviation 5.6
Values 21 13
[62]
THLE FZD7
Mean 3.09
Standard deviation 0.13
Values 3.2 3
[63]
liver FZD7
Mean 0.554
Standard deviation 0.38
Values 0.38 0.47 0.26 1.1
[64]
ref_hepatocyte NOXO1
Mean 0.29
Standard deviation 0.33
Values 0.21 0 0 0.47 0.76
[65]
HepG2 NOXO1
Mean 0.451
Standard deviation 0.2
Values 0.31 0.59
[66]
HepG2.C3A NOXO1
Mean 0.996
Standard deviation 0.24
Values 1.2 0.83
[67]
HuH.7 NOXO1
Mean 0.148
Standard deviation 0.04
Values 0.16 0.1 0.18
[68]
SNU475 NOXO1
Mean 0.0941
Standard deviation 0.068
Values 0.046 0.14
[69]
THLE NOXO1
Mean 0.124
Standard deviation 0.058
Values 0.083 0.16
[70]
liver NOXO1
Mean 0.25
Standard deviation 0.1
Values 0.12 0.24 0.28 0.36
[71]
ref_hepatocyte WNT5A
Mean 0.261
Standard deviation 0.17
Values 0 0.4 0.23 0.25 0.43
[72]
HepG2 WNT5A
Mean 0.063
Standard deviation 0.041
Values 0.092 0.034
[73]
HepG2.C3A WNT5A
Mean 0.0565
Standard deviation 0.011
Values 0.049 0.064
[74]
HuH.7 WNT5A
Mean 0.122
Standard deviation 0.062
Values 0.18 0.13 0.056
[75]
SNU475 WNT5A
Mean 46.2
Standard deviation 6.6
Values 51 42
[76]
THLE WNT5A
Mean 154
Standard deviation 20
Values 1.7e+02 1.4e+02
[77]
liver WNT5A
Mean 0.919
Standard deviation 0.41
Values 0.54 1.3 0.59 1.2
[78]
ref_hepatocyte NOX1
Mean 0.0251
Standard deviation 0.034
Values 0 0 0 0.06 0.065
[79]
HepG2 NOX1
Mean 0.0708
Standard deviation 0.027
Values 0.052 0.09
[80]
HepG2.C3A NOX1
Mean 0.037
Standard deviation 0.039
Values 0.0097 0.064
[81]
HuH.7 NOX1
Mean 1.27
Standard deviation 0.85
Values 1.8 0.29 1.8
[82]
SNU475 NOX1
Mean 0.0441
Standard deviation 0.016
Values 0.032 0.056
[83]
THLE NOX1
Mean 0.129
Standard deviation 0.069
Values 0.18 0.08
[84]
liver NOX1
Mean 0.0636
Standard deviation 0.1
Values 0.21 0.043 0 0