REACTOME_KERATAN_SULFATE_KERATIN_METABOLISM |
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Order |
Gene |
Description |
ref_hepatocyte |
HepG2 |
HepG2.C3A |
HuH.7 |
SNU475 |
THLE |
liver |
1 |
HEXB |
Beta-hexosaminidase subunit beta |
[1] |
-0.62[2] |
-0.90[3] |
-0.70[4] |
-1.12[5] |
-0.65[6] |
-0.83[7] |
2 |
SLC35D2 |
UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter |
[8] |
-1.61[9] |
-0.54[10] |
-0.56[11] |
-2.75[12] |
-3.94[13] |
-2.66[14] |
3 |
B4GALT1 |
Beta-1,4-galactosyltransferase 1 |
[15] |
-0.51[16] |
-0.53[17] |
0.07[18] |
-0.43[19] |
1.08[20] |
0.12[21] |
4 |
GLB1 |
Beta-galactosidase |
[22] |
0.26[23] |
0.00[24] |
0.68[25] |
-0.89[26] |
-0.40[27] |
-0.41[28] |
5 |
HEXA |
Beta-hexosaminidase subunit alpha |
[29] |
1.05[30] |
0.49[31] |
-0.18[32] |
0.49[33] |
0.11[34] |
-0.28[35] |
6 |
ST3GAL1 |
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase
1 |
-0.57[36] |
-1.28[37] |
-0.41[38] |
-0.36[39] |
-0.68[40] |
1.88[41] |
7 |
B4GALT2 |
Beta-1,4-galactosyltransferase 2 |
[42] |
0.19[43] |
0.13[44] |
-0.39[45] |
-0.83[46] |
-1.55[47] |
-2.51[48] |
8 |
GNS |
N-acetylglucosamine-6-sulfatase |
[49] |
1.39[50] |
1.14[51] |
1.54[52] |
1.78[53] |
1.76[54] |
1.71[55] |
9 |
ST3GAL6 |
Type 2 lactosamine alpha-2,3-sialyltransferase |
[56] |
-2.72[57] |
-0.86[58] |
-0.29[59] |
-7.08[60] |
-2.23[61] |
0.11[62] |
10 |
B4GALT4 |
Beta-1,4-galactosyltransferase 4 |
[63] |
-1.03[64] |
-0.26[65] |
-0.21[66] |
-1.37[67] |
-0.81[68] |
-1.16[69] |
11 |
B4GALT5 |
Beta-1,4-galactosyltransferase 5 |
[70] |
1.43[71] |
1.23[72] |
0.01[73] |
2.19[74] |
1.20[75] |
-0.55[76] |
12 |
B3GNT2 |
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2 |
[77] |
-0.57[78] |
0.87[79] |
-0.95[80] |
-0.23[81] |
-1.06[82] |
-0.48[83] |
13 |
ST3GAL4 |
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase
4 |
-1.17[84] |
-1.53[85] |
-3.88[86] |
0.25[87] |
-0.68[88] |
-1.63[89] |
14 |
B4GALT3 |
Beta-1,4-galactosyltransferase 3 |
[90] |
0.55[91] |
0.83[92] |
0.73[93] |
0.27[94] |
-0.06[95] |
-0.35[96] |
15 |
ST3GAL2 |
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase
2 |
1.46[97] |
1.40[98] |
2.19[99] |
2.10[100] |
1.09[101] |
0.21[102] |
16 |
GALNS |
N-acetylgalactosamine-6-sulfatase |
[103] |
1.21[104] |
0.42[105] |
0.12[106] |
0.30[107] |
0.11[108] |
0.25[109] |
17 |
ST3GAL3 |
CMP-N-acetylneuraminate-beta-1,4-galactoside
alpha-2,3-sialyltransferase |
-0.50[110] |
-0.16[111] |
-0.38[112] |
-0.58[113] |
-0.35[114] |
-0.86[115] |
18 |
GLB1L |
Beta-galactosidase-1-like protein |
[116] |
-0.48[117] |
0.20[118] |
-0.22[119] |
-0.37[120] |
-0.14[121] |
-0.80[122] |
19 |
B3GNT3 |
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3 |
[123] |
2.06[124] |
3.44[125] |
-3.03[126] |
-4.23[127] |
-4.80[128] |
-0.43[129] |
20 |
B3GNT7 |
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 |
[130] |
1.16[131] |
-4.51[132] |
-0.94[133] |
-2.35[134] |
-4.28[135] |
0.03[136] |
21 |
CHST2 |
Carbohydrate sulfotransferase 2 |
[137] |
-7.71[138] |
-7.53[139] |
-9.16[140] |
-1.15[141] |
3.29[142] |
-0.50[143] |
22 |
LUM |
Lumican |
[144] |
-5.82[145] |
-7.34[146] |
-5.42[147] |
4.97[148] |
3.98[149] |
3.06[150] |
23 |
PRELP |
Prolargin |
[151] |
-3.59[152] |
-1.72[153] |
-2.69[154] |
-2.11[155] |
-2.89[156] |
3.19[157] |
24 |
B4GALT6 |
Beta-1,4-galactosyltransferase 6 |
[158] |
0.03[159] |
1.18[160] |
1.37[161] |
3.36[162] |
2.10[163] |
0.38[164] |
25 |
CHST1 |
Carbohydrate sulfotransferase 1 |
[165] |
-3.19[166] |
-1.83[167] |
-3.21[168] |
-3.34[169] |
1.34[170] |
-0.20[171] |
26 |
CHST6 |
Carbohydrate sulfotransferase 6 |
[172] |
2.86[173] |
2.54[174] |
1.63[175] |
0.10[176] |
0.64[177] |
-0.28[178] |
27 |
FMOD |
Fibromodulin |
[179] |
-3.73[180] |
[181] |
0.48[182] |
2.37[183] |
2.88[184] |
2.83[185] |
28 |
OGN |
Mimecan |
[186] |
[187] |
-2.81[188] |
-3.59[189] |
-4.88[190] |
-3.17[191] |
2.66[192] |
29 |
B3GNT4 |
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 4 |
[193] |
2.40[194] |
2.01[195] |
1.54[196] |
2.11[197] |
1.96[198] |
1.37[199] |
30 |
CHST5 |
Carbohydrate sulfotransferase 5 |
[200] |
0.78[201] |
2.38[202] |
1.64[203] |
1.31[204] |
1.13[205] |
1.94[206] |
31 |
OMD |
Osteomodulin |
[207] |
[208] |
[209] |
-2.15[210] |
-1.21[211] |
-0.17[212] |
4.45[213] |
32 |
ACAN |
Aggrecan core protein |
[214] |
[215] |
[216] |
[217] |
[218] |
[219] |
[220] |
33 |
B4GAT1 |
Beta-1,4-glucuronyltransferase 1 |
[221] |
[222] |
[223] |
[224] |
[225] |
[226] |
[227] |
34 |
KERA |
Keratocan |
[228] |
[229] |
[230] |
[231] |
[232] |
[233] |
[234] |
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