REACTOME_KERATAN_SULFATE_DEGRADATION Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 HEXB Beta-hexosaminidase subunit beta [1] -1.04[2] -0.97[3] -0.94[4] -1.42[5] -0.92[6] -1.00[7]
2 GLB1 Beta-galactosidase [8] -0.16[9] -0.06[10] 0.45[11] -1.19[12] -0.67[13] -0.58[14]
3 HEXA Beta-hexosaminidase subunit alpha [15] 0.62[16] 0.42[17] -0.41[18] 0.19[19] -0.16[20] -0.45[21]
4 GNS N-acetylglucosamine-6-sulfatase [22] 0.97[23] 1.08[24] 1.30[25] 1.48[26] 1.48[27] 1.54[28]
5 GALNS N-acetylgalactosamine-6-sulfatase [29] 0.78[30] 0.36[31] -0.12[32] 0.00[33] -0.16[34] 0.08[35]
6 GLB1L Beta-galactosidase-1-like protein [36] -0.91[37] 0.14[38] -0.46[39] -0.67[40] -0.41[41] -0.97[42]
7 LUM Lumican [43] -6.25[44] -7.40[45] -5.66[46] 4.67[47] 3.71[48] 2.89[49]
8 PRELP Prolargin [50] -4.02[51] -1.78[52] -2.92[53] -2.41[54] -3.16[55] 3.02[56]
9 FMOD Fibromodulin [57] -4.16[58] [59] 0.25[60] 2.07[61] 2.61[62] 2.66[63]
10 OGN Mimecan [64] [65] -2.87[66] -3.83[67] -5.18[68] -3.44[69] 2.49[70]
11 OMD Osteomodulin [71] [72] [73] -2.39[74] -1.51[75] -0.45[76] 4.28[77]
12 KERA Keratocan [78] [79] [80] [81] [82] [83] [84]
13 ACAN Aggrecan core protein [85] [86] [87] [88] [89] [90] [91]
[1]
ref_hepatocyte HEXB
Mean 33.9
Standard deviation 11
Values 39 33 16 44 38
[2]
HepG2 HEXB
Mean 64.1
Standard deviation 5.9
Values 68 60
[3]
HepG2.C3A HEXB
Mean 43.4
Standard deviation 2.1
Values 45 42
[4]
HuH.7 HEXB
Mean 61.5
Standard deviation 15
Values 46 77 61
[5]
SNU475 HEXB
Mean 37.4
Standard deviation 0.5
Values 37 38
[6]
THLE HEXB
Mean 71.3
Standard deviation 17
Values 59 83
[7]
liver HEXB
Mean 39
Standard deviation 15
Values 42 34 57 22
[8]
ref_hepatocyte GLB1
Mean 15.3
Standard deviation 5.7
Values 22 9.9 8.6 18 18
[9]
HepG2 GLB1
Mean 53.1
Standard deviation 4.7
Values 56 50
[10]
HepG2.C3A GLB1
Mean 36.7
Standard deviation 8.2
Values 42 31
[11]
HuH.7 GLB1
Mean 72.4
Standard deviation 9.9
Values 62 81 75
[12]
SNU475 GLB1
Mean 19.7
Standard deviation 1.4
Values 19 21
[13]
THLE GLB1
Mean 38.2
Standard deviation 4.9
Values 35 42
[14]
liver GLB1
Mean 23.6
Standard deviation 8.2
Values 23 20 35 16
[15]
ref_hepatocyte HEXA
Mean 15.3
Standard deviation 8.5
Values 11 11 6.1 25 24
[16]
HepG2 HEXA
Mean 91.6
Standard deviation 1.4
Values 93 91
[17]
HepG2.C3A HEXA
Mean 51.3
Standard deviation 2.1
Values 53 50
[18]
HuH.7 HEXA
Mean 39.8
Standard deviation 6.4
Values 37 35 47
[19]
SNU475 HEXA
Mean 51.2
Standard deviation 9
Values 58 45
[20]
THLE HEXA
Mean 54.1
Standard deviation 9.1
Values 48 61
[21]
liver HEXA
Mean 25.8
Standard deviation 15
Values 28 17 46 12
[22]
ref_hepatocyte GNS
Mean 10.7
Standard deviation 4.8
Values 17 13 4 12 8.4
[23]
HepG2 GNS
Mean 81.3
Standard deviation 7.9
Values 87 76
[24]
HepG2.C3A GNS
Mean 56.4
Standard deviation 4.7
Values 60 53
[25]
HuH.7 GNS
Mean 91.4
Standard deviation 13
Values 1e+02 97 77
[26]
SNU475 GNS
Mean 87.8
Standard deviation 16
Values 99 77
[27]
THLE GNS
Mean 119
Standard deviation 32
Values 96 1.4e+02
[28]
liver GNS
Mean 71.6
Standard deviation 24
Values 44 1e+02 66 76
[29]
ref_hepatocyte GALNS
Mean 2.75
Standard deviation 1
Values 2.3 1.7 2 4 3.7
[30]
HepG2 GALNS
Mean 18.4
Standard deviation 5.4
Values 22 15
[31]
HepG2.C3A GALNS
Mean 8.83
Standard deviation 1.2
Values 9.7 8
[32]
HuH.7 GALNS
Mean 8.79
Standard deviation 1.8
Values 9.7 6.7 9.9
[33]
SNU475 GALNS
Mean 8.1
Standard deviation 4.4
Values 11 5
[34]
THLE GALNS
Mean 9.76
Standard deviation 0.35
Values 9.5 10
[35]
liver GALNS
Mean 6.69
Standard deviation 2.6
Values 8.1 5.2 9.6 3.9
[36]
ref_hepatocyte GLB1L
Mean 1.01
Standard deviation 0.33
Values 0.78 0.72 1.5 0.85 1.2
[37]
HepG2 GLB1L
Mean 2.08
Standard deviation 0.079
Values 2 2.1
[38]
HepG2.C3A GLB1L
Mean 2.77
Standard deviation 0.12
Values 2.9 2.7
[39]
HuH.7 GLB1L
Mean 2.55
Standard deviation 1
Values 3.2 1.4 3
[40]
SNU475 GLB1L
Mean 1.86
Standard deviation 0.34
Values 2.1 1.6
[41]
THLE GLB1L
Mean 3.01
Standard deviation 0.17
Values 2.9 3.1
[42]
liver GLB1L
Mean 1.18
Standard deviation 0.44
Values 1.1 1.2 1.8 0.7
[43]
ref_hepatocyte LUM
Mean 0.363
Standard deviation 0.66
Values 0 0 0.3 0 1.5
[44]
HepG2 LUM
Mean 0.0186
Standard deviation 0.01
Values 0.011 0.026
[45]
HepG2.C3A LUM
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[46]
HuH.7 LUM
Mean 0.025
Standard deviation 0.025
Values 0.049 0.026 0
[47]
SNU475 LUM
Mean 27.1
Standard deviation 6
Values 31 23
[48]
THLE LUM
Mean 18.8
Standard deviation 8.1
Values 25 13
[49]
liver LUM
Mean 6.21
Standard deviation 3.8
Values 5.9 6.6 11 1.5
[50]
ref_hepatocyte PRELP
Mean 0.346
Standard deviation 0.43
Values 0.047 0.065 1.1 0.12 0.43
[51]
HepG2 PRELP
Mean 0.083
Standard deviation 0.077
Values 0.029 0.14
[52]
HepG2.C3A PRELP
Mean 0.252
Standard deviation 0.054
Values 0.21 0.29
[53]
HuH.7 PRELP
Mean 0.158
Standard deviation 0.026
Values 0.14 0.15 0.19
[54]
SNU475 PRELP
Mean 0.191
Standard deviation 0.06
Values 0.15 0.23
[55]
THLE PRELP
Mean 0.153
Standard deviation 0.051
Values 0.19 0.12
[56]
liver PRELP
Mean 6.44
Standard deviation 5.5
Values 14 1.3 8 3
[57]
ref_hepatocyte FMOD
Mean 0.122
Standard deviation 0.066
Values 0.078 0.2 0.052 0.095 0.19
[58]
HepG2 FMOD
Mean 0.0265
Standard deviation 0.019
Values 0.04 0.013
[59]
HepG2.C3A FMOD
Mean 0
Standard deviation 0
Values 0 0
[60]
HuH.7 FMOD
Mean 0.5
Standard deviation 0.33
Values 0.61 0.13 0.76
[61]
SNU475 FMOD
Mean 1.5
Standard deviation 1.5
Values 0.47 2.5
[62]
THLE FMOD
Mean 2.94
Standard deviation 1
Values 3.7 2.2
[63]
liver FMOD
Mean 1.77
Standard deviation 0.78
Values 1.5 1.4 2.9 1.2
[64]
ref_hepatocyte OGN
Mean 0.0598
Standard deviation 0.13
Values 0 0 0.3 0 0
[65]
HepG2 OGN
Mean 0
Standard deviation 0
Values 0 0
[66]
HepG2.C3A OGN
Mean 0.0204
Standard deviation 0.0014
Values 0.019 0.021
[67]
HuH.7 OGN
Mean 0.0146
Standard deviation 0.02
Values 0 0.0064 0.037
[68]
SNU475 OGN
Mean 0.00485
Standard deviation 0.0003
Values 0.0046 0.0051
[69]
THLE OGN
Mean 0.0219
Standard deviation 0.014
Values 0.012 0.032
[70]
liver OGN
Mean 0.773
Standard deviation 0.24
Values 0.56 0.84 1.1 0.61
[71]
ref_hepatocyte OMD
Mean 0.0121
Standard deviation 0.027
Values 0 0 0 0.06 0
[72]
HepG2 OMD
Mean 0
Standard deviation 0
Values 0 0
[73]
HepG2.C3A OMD
Mean 0
Standard deviation 0
Values 0 0
[74]
HuH.7 OMD
Mean 0.008
Standard deviation 0.0015
Values 0.0082 0.0064 0.0094
[75]
SNU475 OMD
Mean 0.0125
Standard deviation 0.011
Values 0.0046 0.02
[76]
THLE OMD
Mean 0.0352
Standard deviation 0.042
Values 0.065 0.0053
[77]
liver OMD
Mean 0.539
Standard deviation 0.18
Values 0.33 0.76 0.49 0.58
[78]
ref_hepatocyte KERA
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[79]
HepG2 KERA
Mean 0
Standard deviation 0
Values 0 0
[80]
HepG2.C3A KERA
Mean 0
Standard deviation 0
Values 0 0
[81]
HuH.7 KERA
Mean 0
Standard deviation 0
Values 0 0 0
[82]
SNU475 KERA
Mean 0.00949
Standard deviation 0.0063
Values 0.014 0.0051
[83]
THLE KERA
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[84]
liver KERA
Mean 0
Standard deviation 0
Values 0 0 0 0
[85]
ref_hepatocyte ACAN
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[86]
HepG2 ACAN
Mean 0
Standard deviation 0
Values 0 0
[87]
HepG2.C3A ACAN
Mean 0
Standard deviation 0
Values 0 0
[88]
HuH.7 ACAN
Mean 0
Standard deviation 0
Values 0 0 0
[89]
SNU475 ACAN
Mean 0.0118
Standard deviation 0.0095
Values 0.019 0.0051
[90]
THLE ACAN
Mean 0.0136
Standard deviation 0.011
Values 0.0059 0.021
[91]
liver ACAN
Mean 0.0272
Standard deviation 0.033
Values 0 0.043 0 0.066