REACTOME_IRS_ACTIVATION Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 INSR Insulin receptor [1] -1.07[2] 0.41[3] 0.27[4] -3.38[5] -1.98[6] 0.85[7]
2 GRB10 Growth factor receptor-bound protein 10 [8] 0.98[9] -1.27[10] -0.46[11] 0.39[12] 0.05[13] -1.22[14]
3 IRS1 Insulin receptor substrate 1 [15] 0.56[16] 0.84[17] 0.69[18] 1.41[19] -0.22[20] -1.04[21]
4 IRS2 Insulin receptor substrate 2 [22] -7.18[23] [24] -5.06[25] -0.96[26] 1.66[27] -0.77[28]
5 INS Insulin [29] [30] [31] [32] [33] [34] [35]
[1]
ref_hepatocyte INSR
Mean 5.73
Standard deviation 1.4
Values 6.5 5 4.1 5.3 7.7
[2]
HepG2 INSR
Mean 17.4
Standard deviation 4.9
Values 21 14
[3]
HepG2.C3A INSR
Mean 24.3
Standard deviation 6.7
Values 29 20
[4]
HuH.7 INSR
Mean 62.9
Standard deviation 26
Values 58 91 39
[5]
SNU475 INSR
Mean 1.24
Standard deviation 0.29
Values 1.4 1
[6]
THLE INSR
Mean 8.45
Standard deviation 0.32
Values 8.2 8.7
[7]
liver INSR
Mean 131
Standard deviation 15
Values 1.4e+02 1.5e+02 1.1e+02 1.3e+02
[8]
ref_hepatocyte GRB10
Mean 3.75
Standard deviation 1.1
Values 2 3.4 4.9 4.1 4.3
[9]
HepG2 GRB10
Mean 47
Standard deviation 17
Values 59 35
[10]
HepG2.C3A GRB10
Mean 4.96
Standard deviation 0.92
Values 5.6 4.3
[11]
HuH.7 GRB10
Mean 24.7
Standard deviation 7
Values 22 33 19
[12]
SNU475 GRB10
Mean 11.1
Standard deviation 1.2
Values 12 10
[13]
THLE GRB10
Mean 22.6
Standard deviation 0.57
Values 22 23
[14]
liver GRB10
Mean 20.5
Standard deviation 8.3
Values 22 21 9.1 29
[15]
ref_hepatocyte IRS1
Mean 3.05
Standard deviation 1.4
Values 4.3 1.5 2.7 2.1 4.7
[16]
HepG2 IRS1
Mean 28.7
Standard deviation 8.6
Values 35 23
[17]
HepG2.C3A IRS1
Mean 17.4
Standard deviation 6
Values 22 13
[18]
HuH.7 IRS1
Mean 44.8
Standard deviation 6.6
Values 49 48 37
[19]
SNU475 IRS1
Mean 18.3
Standard deviation 5.2
Values 15 22
[20]
THLE IRS1
Mean 15.3
Standard deviation 0.24
Values 15 15
[21]
liver IRS1
Mean 18.8
Standard deviation 4.8
Values 23 18 12 22
[22]
ref_hepatocyte IRS2
Mean 2.12
Standard deviation 2.3
Values 0.019 0.61 1.4 5.7 2.9
[23]
HepG2 IRS2
Mean 0.0931
Standard deviation 0.071
Values 0.14 0.043
[24]
HepG2.C3A IRS2
Mean 0
Standard deviation 0
Values 0 0
[25]
HuH.7 IRS2
Mean 0.575
Standard deviation 0.68
Values 0.2 1.4 0.17
[26]
SNU475 IRS2
Mean 2.45
Standard deviation 0.45
Values 2.1 2.8
[27]
THLE IRS2
Mean 39
Standard deviation 5.9
Values 35 43
[28]
liver IRS2
Mean 15.7
Standard deviation 9.9
Values 29 11 6.3 17
[29]
ref_hepatocyte INS
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[30]
HepG2 INS
Mean 0.00287
Standard deviation 0.0041
Values 0.0057 0
[31]
HepG2.C3A INS
Mean 0
Standard deviation 0
Values 0 0
[32]
HuH.7 INS
Mean 0
Standard deviation 0
Values 0 0 0
[33]
SNU475 INS
Mean 0
Standard deviation 0
Values 0 0
[34]
THLE INS
Mean 0
Standard deviation 0
Values 0 0
[35]
liver INS
Mean 0.0838
Standard deviation 0.13
Values 0 0.057 0 0.28