REACTOME_IRON_UPTAKE_AND_TRANSPORT | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | FTL | Ferritin light chain | [1] | -0.52[2] | -1.17[3] | -1.04[4] | 0.26[5] | -1.29[6] | -0.48[7] |
2 | TF | Serotransferrin | [8] | 0.43[9] | 1.49[10] | 0.64[11] | -8.88[12] | -8.05[13] | 0.66[14] |
3 | FTH1 | Ferritin heavy chain | [15] | 0.56[16] | -0.82[17] | 0.75[18] | 0.83[19] | 1.84[20] | -0.39[21] |
4 | UBB | Polyubiquitin-B | [22] | -0.48[23] | -0.92[24] | -0.33[25] | -1.11[26] | 0.14[27] | -1.09[28] |
5 | RPS27A | Ubiquitin-40S ribosomal protein S27a | [29] | [30] | [31] | [32] | [33] | [34] | [35] |
6 | UBC | Polyubiquitin-C | [36] | -0.04[37] | -0.17[38] | 0.03[39] | -0.26[40] | 0.52[41] | -0.64[42] |
7 | CP | Ceruloplasmin | [43] | -1.84[44] | 1.02[45] | -0.06[46] | -3.65[47] | -8.60[48] | 2.52[49] |
8 | TFR2 | Transferrin receptor protein 2 | [50] | -3.33[51] | -2.13[52] | -0.87[53] | -11.85[54] | -8.37[55] | 1.12[56] |
9 | NEDD8 | NEDD8 | [57] | -0.02[58] | -1.83[59] | -1.15[60] | -1.62[61] | -0.68[62] | -2.74[63] |
10 | ATP6V0E1 | V-type proton ATPase subunit e 1 | [64] | 0.37[65] | -0.54[66] | 0.03[67] | 0.34[68] | 0.68[69] | -0.49[70] |
11 | SKP1 | S-phase kinase-associated protein 1 | [71] | 0.74[72] | 0.89[73] | 0.46[74] | 1.16[75] | 2.17[76] | 0.09[77] |
12 | ATP6V0B | V-type proton ATPase 21 kDa proteolipid subunit | [78] | 0.18[79] | 0.13[80] | 0.01[81] | -0.04[82] | 1.11[83] | 0.08[84] |
13 | UBA52 | Ubiquitin-60S ribosomal protein L40 | [85] | 2.40[86] | 2.07[87] | 3.54[88] | 1.14[89] | 2.74[90] | 0.13[91] |
14 | ATP6V0C | V-type proton ATPase 16 kDa proteolipid subunit | [92] | 0.60[93] | -0.08[94] | 0.28[95] | -0.20[96] | 1.38[97] | -0.82[98] |
15 | HMOX1 | Heme oxygenase 1 | [99] | 1.24[100] | 0.07[101] | -0.61[102] | 0.07[103] | 0.62[104] | -1.29[105] |
16 | ATP6V1G1 | V-type proton ATPase subunit G 1 | [106] | 1.02[107] | 0.89[108] | 1.12[109] | 0.83[110] | 1.81[111] | 0.19[112] |
17 | GLRX3 | Glutaredoxin-3 | [113] | 0.94[114] | 1.53[115] | 0.91[116] | 0.01[117] | 1.44[118] | -1.40[119] |
18 | ATP6V1F | V-type proton ATPase subunit F | [120] | 0.49[121] | 0.06[122] | 0.51[123] | 0.23[124] | 1.10[125] | -1.16[126] |
19 | ATP6V1E1 | V-type proton ATPase subunit E 1 | [127] | 1.29[128] | 0.96[129] | 1.57[130] | 1.56[131] | 2.39[132] | -0.83[133] |
20 | LCN2 | Neutrophil gelatinase-associated lipocalin | [134] | -3.08[135] | 0.09[136] | -5.97[137] | -6.71[138] | -3.66[139] | -2.15[140] |
21 | SLC40A1 | Solute carrier family 40 member 1 | [141] | 1.99[142] | 1.63[143] | 2.15[144] | -0.03[145] | -2.04[146] | 2.67[147] |
22 | HMOX2 | Heme oxygenase 2 | [148] | 0.51[149] | 0.33[150] | -1.11[151] | -0.95[152] | 0.56[153] | 0.31[154] |
23 | ACO1 | Cytoplasmic aconitate hydratase | [155] | 0.12[156] | -0.03[157] | 0.61[158] | 0.06[159] | 2.73[160] | 1.90[161] |
24 | STEAP3 | Metalloreductase STEAP3 | [162] | 0.25[163] | -0.71[164] | -2.46[165] | 0.28[166] | 0.17[167] | 2.49[168] |
25 | ATP6AP1 | V-type proton ATPase subunit S1 | [169] | 2.24[170] | 1.73[171] | 2.39[172] | 1.57[173] | 2.86[174] | 0.37[175] |
26 | ATP6V0D1 | V-type proton ATPase subunit d 1 | [176] | 1.45[177] | 0.73[178] | 1.55[179] | 1.61[180] | 2.22[181] | 0.81[182] |
27 | ATP6V1B2 | V-type proton ATPase subunit B, brain isoform | [183] | 1.89[184] | 1.59[185] | 2.52[186] | 1.44[187] | 2.59[188] | 0.80[189] |
28 | ATP6V1D | V-type proton ATPase subunit D | [190] | 0.94[191] | 0.50[192] | 0.38[193] | 1.57[194] | 2.78[195] | -0.05[196] |
29 | ATP6V0E2 | V-type proton ATPase subunit e 2 | [197] | 2.32[198] | 2.41[199] | -4.49[200] | 0.82[201] | 0.61[202] | 0.98[203] |
30 | TFRC | Transferrin receptor protein 1 | [204] | 5.16[205] | 4.41[206] | 4.97[207] | 3.12[208] | 5.39[209] | 2.37[210] |
31 | CUL1 | Cullin-1 | [211] | 1.34[212] | 1.77[213] | 1.76[214] | 2.25[215] | 2.69[216] | 1.54[217] |
32 | FBXL5 | F-box/LRR-repeat protein 5 | [218] | 0.27[219] | -0.08[220] | 2.03[221] | 1.57[222] | 2.05[223] | 1.96[224] |
33 | ATP6V1A | V-type proton ATPase catalytic subunit A | [225] | 2.09[226] | 2.16[227] | 2.80[228] | 2.81[229] | 3.37[230] | 2.54[231] |
34 | TCIRG1 | V-type proton ATPase 116 kDa subunit a isoform 3 | [232] | 1.77[233] | 2.02[234] | 2.38[235] | 4.00[236] | 3.01[237] | 1.61[238] |
35 | ATP6V1H | V-type proton ATPase subunit H | [239] | 1.40[240] | 1.05[241] | 0.65[242] | 2.29[243] | 2.98[244] | 0.23[245] |
36 | IREB2 | Iron-responsive element-binding protein 2 | [246] | 2.06[247] | 3.00[248] | 3.88[249] | 3.05[250] | 3.39[251] | 1.89[252] |
37 | SLC11A2 | Natural resistance-associated macrophage protein 2 | [253] | 3.38[254] | 3.94[255] | 2.53[256] | 1.67[257] | 3.21[258] | 2.47[259] |
38 | ATP6V0A1 | V-type proton ATPase 116 kDa subunit a isoform 1 | [260] | 2.19[261] | 1.83[262] | 3.78[263] | 2.33[264] | 2.87[265] | 2.51[266] |
39 | CAND1 | Cullin-associated NEDD8-dissociated protein 1 | [267] | 3.32[268] | 4.21[269] | 4.80[270] | 4.43[271] | 5.33[272] | 3.18[273] |
40 | ATP6V1C1 | V-type proton ATPase subunit C 1 | [274] | 2.87[275] | 2.95[276] | 3.57[277] | 3.96[278] | 4.28[279] | 2.11[280] |
41 | SLC46A1 | Proton-coupled folate transporter | [281] | 1.63[282] | 1.78[283] | 1.95[284] | 0.34[285] | 0.72[286] | 2.00[287] |
42 | MCOLN1 | Mucolipin-1 | [288] | 0.91[289] | 0.01[290] | 1.26[291] | 1.11[292] | 2.64[293] | 0.86[294] |
43 | ABCG2 | ATP-binding cassette sub-family G member 2 | [295] | 1.78[296] | 1.42[297] | 2.99[298] | 1.32[299] | 1.00[300] | 1.06[301] |
44 | FLVCR1 | Feline leukemia virus subgroup C receptor-related protein 1 | [302] | 2.67[303] | 3.78[304] | 4.00[305] | 2.85[306] | 2.63[307] | 1.09[308] |
45 | HFE | Hereditary hemochromatosis protein | [309] | 1.28[310] | 0.58[311] | 1.06[312] | 2.74[313] | 2.89[314] | 1.56[315] |
46 | STEAP2 | Metalloreductase STEAP2 | [316] | 1.08[317] | 2.86[318] | 3.13[319] | 2.30[320] | 4.06[321] | 1.94[322] |
47 | ATP6V0A2 | V-type proton ATPase 116 kDa subunit a isoform 2 | [323] | 3.06[324] | 3.64[325] | 3.41[326] | 2.87[327] | 4.19[328] | 2.97[329] |
48 | ATP6V0D2 | V-type proton ATPase subunit d 2 | [330] | -2.56[331] | -2.97[332] | -2.55[333] | -4.29[334] | -0.67[335] | -6.05[336] |
49 | ATP6V1E2 | V-type proton ATPase subunit E 2 | [337] | -0.18[338] | -0.89[339] | -0.48[340] | -0.45[341] | 0.25[342] | -0.80[343] |
50 | CYBRD1 | Cytochrome b reductase 1 | [344] | 1.09[345] | -2.48[346] | 2.04[347] | 6.57[348] | 7.22[349] | 4.11[350] |
51 | SLC22A17 | Solute carrier family 22 member 17 | [351] | 2.27[352] | [353] | -5.01[354] | 3.13[355] | 5.63[356] | 1.61[357] |
52 | ATP6V1C2 | V-type proton ATPase subunit C 2 | [358] | 2.54[359] | 2.99[360] | 1.86[361] | 2.28[362] | 2.12[363] | 1.70[364] |
53 | ATP6V1G2 | V-type proton ATPase subunit G 2 | [365] | 1.50[366] | 2.27[367] | 2.36[368] | 2.01[369] | 4.82[370] | 0.24[371] |
54 | ATP6V1B1 | V-type proton ATPase subunit B, kidney isoform | [372] | 0.64[373] | 3.87[374] | 4.45[375] | 2.61[376] | 1.82[377] | -1.59[378] |
55 | HEPH | Hephaestin | [379] | 1.67[380] | [381] | 1.47[382] | -1.89[383] | 7.78[384] | 4.70[385] |
56 | ATP6V0A4 | V-type proton ATPase 116 kDa subunit a isoform 4 | [386] | [387] | [388] | [389] | [390] | [391] | [392] |
57 | FTMT | Ferritin, mitochondrial | [393] | [394] | [395] | [396] | [397] | [398] | [399] |
58 | ATP6V1G3 | V-type proton ATPase subunit G 3 | [400] | [401] | [402] | [403] | [404] | [405] | [406] |