REACTOME_IRF3_MEDIATED_ACTIVATION_OF_TYPE_1_IFN Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 IRF3 Interferon regulatory factor 3 [1] 0.17[2] -0.28[3] 0.10[4] -0.10[5] -0.11[6] -1.66[7]
2 TBK1 Serine/threonine-protein kinase TBK1 [8] -0.76[9] 0.30[10] -0.90[11] 0.04[12] 0.52[13] 0.00[14]
3 DTX4 E3 ubiquitin-protein ligase DTX4 [15] 0.76[16] 0.16[17] 1.03[18] 0.32[19] -2.75[20] 1.91[21]
4 ZBP1 Z-DNA-binding protein 1 [22] -4.43[23] -4.24[24] -5.50[25] -3.16[26] -3.03[27] -0.98[28]
5 NLRP4 NACHT, LRR and PYD domains-containing protein 4 [29] [30] [31] [32] [33] [34] [35]
[1]
ref_hepatocyte IRF3
Mean 10
Standard deviation 4.1
Values 7.1 4.7 13 15 10
[2]
HepG2 IRF3
Mean 27.2
Standard deviation 6.6
Values 32 23
[3]
HepG2.C3A IRF3
Mean 27.3
Standard deviation 1.4
Values 28 26
[4]
HuH.7 IRF3
Mean 43.3
Standard deviation 14
Values 47 28 54
[5]
SNU475 IRF3
Mean 23.5
Standard deviation 4.3
Values 20 27
[6]
THLE IRF3
Mean 19.9
Standard deviation 0.46
Values 20 20
[7]
liver IRF3
Mean 6.27
Standard deviation 2.8
Values 8.8 3.7 8.7 4
[8]
ref_hepatocyte TBK1
Mean 6.94
Standard deviation 1.7
Values 7.8 8.4 8.4 5 5.2
[9]
HepG2 TBK1
Mean 9.87
Standard deviation 3.8
Values 7.2 13
[10]
HepG2.C3A TBK1
Mean 28.1
Standard deviation 7.6
Values 23 33
[11]
HuH.7 TBK1
Mean 14.9
Standard deviation 0.71
Values 14 16 15
[12]
SNU475 TBK1
Mean 17.9
Standard deviation 1.5
Values 19 17
[13]
THLE TBK1
Mean 21.3
Standard deviation 2.3
Values 23 20
[14]
liver TBK1
Mean 13.7
Standard deviation 2.9
Values 13 15 17 10
[15]
ref_hepatocyte DTX4
Mean 2.52
Standard deviation 1.8
Values 0.67 1.7 1.6 4.9 3.8
[16]
HepG2 DTX4
Mean 10.3
Standard deviation 1.7
Values 9.1 12
[17]
HepG2.C3A DTX4
Mean 9.29
Standard deviation 0.13
Values 9.2 9.4
[18]
HuH.7 DTX4
Mean 20.7
Standard deviation 3.3
Values 23 22 17
[19]
SNU475 DTX4
Mean 7.93
Standard deviation 2.6
Values 9.8 6.1
[20]
THLE DTX4
Mean 0.804
Standard deviation 0.22
Values 0.64 0.96
[21]
liver DTX4
Mean 18.7
Standard deviation 4.9
Values 17 25 14 19
[22]
ref_hepatocyte ZBP1
Mean 0.153
Standard deviation 0.17
Values 0.13 0.065 0 0.12 0.45
[23]
HepG2 ZBP1
Mean 0.0172
Standard deviation 2.3e-05
Values 0.017 0.017
[24]
HepG2.C3A ZBP1
Mean 0.0268
Standard deviation 0.038
Values 0 0.054
[25]
HuH.7 ZBP1
Mean 0.0137
Standard deviation 0.014
Values 0 0.013 0.028
[26]
SNU475 ZBP1
Mean 0.0432
Standard deviation 0.011
Values 0.051 0.035
[27]
THLE ZBP1
Mean 0.0402
Standard deviation 0.027
Values 0.059 0.021
[28]
liver ZBP1
Mean 0.154
Standard deviation 0.026
Values 0.12 0.17 0.15 0.17
[29]
ref_hepatocyte NLRP4
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[30]
HepG2 NLRP4
Mean 0
Standard deviation 0
Values 0 0
[31]
HepG2.C3A NLRP4
Mean 0
Standard deviation 0
Values 0 0
[32]
HuH.7 NLRP4
Mean 0.00312
Standard deviation 0.0054
Values 0 0 0.0094
[33]
SNU475 NLRP4
Mean 0.0327
Standard deviation 0.04
Values 0.0046 0.061
[34]
THLE NLRP4
Mean 0
Standard deviation 0
Values 0 0
[35]
liver NLRP4
Mean 0
Standard deviation 0
Values 0 0 0 0