REACTOME_IRAK1_RECRUITS_IKK_COMPLEX Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 UBB Polyubiquitin-B [1] -0.33[2] -0.50[3] -0.44[4] -0.44[5] -0.23[6] 0.05[7]
2 RPS27A Ubiquitin-40S ribosomal protein S27a [8] [9] [10] [11] [12] [13] [14]
3 UBC Polyubiquitin-C [15] 0.11[16] 0.25[17] -0.08[18] 0.42[19] 0.15[20] 0.50[21]
4 UBA52 Ubiquitin-60S ribosomal protein L40 [22] 2.55[23] 2.49[24] 3.43[25] 1.81[26] 2.37[27] 1.27[28]
5 UBE2V1 Ubiquitin-conjugating enzyme E2 variant 1 [29] -2.01[30] -2.16[31] -2.12[32] -1.54[33] -2.45[34] -3.08[35]
6 IKBKG NF-kappa-B essential modulator [36] 0.98[37] 1.16[38] -1.19[39] 1.49[40] 0.02[41] 1.32[42]
7 IRAK1 Interleukin-1 receptor-associated kinase 1 [43] 3.29[44] 2.71[45] 1.59[46] 3.14[47] 3.25[48] 1.24[49]
8 UBE2N Ubiquitin-conjugating enzyme E2 N [50] 2.56[51] 3.07[52] 1.79[53] 2.66[54] 2.30[55] 1.21[56]
9 CHUK Inhibitor of nuclear factor kappa-B kinase subunit alpha [57] 2.77[58] 4.02[59] 3.89[60] 2.99[61] 3.55[62] 3.44[63]
10 IKBKB Inhibitor of nuclear factor kappa-B kinase subunit beta [64] 2.39[65] 2.48[66] 2.49[67] 2.60[68] 2.44[69] 3.11[70]
11 PELI1 E3 ubiquitin-protein ligase pellino homolog 1 [71] 2.02[72] 2.96[73] 3.38[74] 2.09[75] 1.92[76] 3.33[77]
12 TRAF6 TNF receptor-associated factor 6 [78] 2.96[79] 2.88[80] 3.35[81] 4.01[82] 3.20[83] 4.84[84]
13 PELI3 E3 ubiquitin-protein ligase pellino homolog 3 [85] 3.24[86] 2.33[87] 3.76[88] 4.83[89] 4.28[90] 2.90[91]
14 PELI2 E3 ubiquitin-protein ligase pellino homolog 2 [92] -0.98[93] -1.85[94] -2.49[95] 6.32[96] 4.79[97] 5.40[98]
[1]
ref_hepatocyte UBB
Mean 764
Standard deviation 4.8e+02
Values 3.8e+02 3.5e+02 5.3e+02 1.2e+03 1.3e+03
[2]
HepG2 UBB
Mean 368
Standard deviation 39
Values 4e+02 3.4e+02
[3]
HepG2.C3A UBB
Mean 285
Standard deviation 14
Values 2.8e+02 3e+02
[4]
HuH.7 UBB
Mean 304
Standard deviation 40
Values 2.9e+02 2.7e+02 3.5e+02
[5]
SNU475 UBB
Mean 204
Standard deviation 3.3
Values 2.1e+02 2e+02
[6]
THLE UBB
Mean 315
Standard deviation 34
Values 2.9e+02 3.4e+02
[7]
liver UBB
Mean 296
Standard deviation 1.3e+02
Values 4.3e+02 2.1e+02 3.9e+02 1.5e+02
[8]
ref_hepatocyte RPS27A
Mean 499
Standard deviation 2.2e+02
Values 6.6e+02 6.1e+02 1.7e+02 6.8e+02 3.8e+02
[9]
HepG2 RPS27A
Missing
[10]
HepG2.C3A RPS27A
Missing
[11]
HuH.7 RPS27A
Missing
[12]
SNU475 RPS27A
Missing
[13]
THLE RPS27A
Missing
[14]
liver RPS27A
Missing
[15]
ref_hepatocyte UBC
Mean 480
Standard deviation 2.8e+02
Values 1.8e+02 3.5e+02 9.1e+02 5.8e+02 3.8e+02
[16]
HepG2 UBC
Mean 314
Standard deviation 38
Values 3.4e+02 2.9e+02
[17]
HepG2.C3A UBC
Mean 302
Standard deviation 41
Values 3.3e+02 2.7e+02
[18]
HuH.7 UBC
Mean 246
Standard deviation 64
Values 2.4e+02 3.1e+02 1.9e+02
[19]
SNU475 UBC
Mean 232
Standard deviation 63
Values 2.8e+02 1.9e+02
[20]
THLE UBC
Mean 257
Standard deviation 41
Values 2.3e+02 2.9e+02
[21]
liver UBC
Mean 254
Standard deviation 78
Values 2.2e+02 3.1e+02 3.3e+02 1.6e+02
[22]
ref_hepatocyte UBA52
Mean 57.3
Standard deviation 43
Values 14 23 49 1.2e+02 81
[23]
HepG2 UBA52
Mean 203
Standard deviation 20
Values 2.2e+02 1.9e+02
[24]
HepG2.C3A UBA52
Mean 169
Standard deviation 3.3
Values 1.7e+02 1.7e+02
[25]
HuH.7 UBA52
Mean 334
Standard deviation 46
Values 3.4e+02 2.8e+02 3.7e+02
[26]
SNU475 UBA52
Mean 72.9
Standard deviation 11
Values 65 81
[27]
THLE UBA52
Mean 144
Standard deviation 15
Values 1.3e+02 1.5e+02
[28]
liver UBA52
Mean 51.7
Standard deviation 26
Values 79 32 68 28
[29]
ref_hepatocyte UBE2V1
Mean 30.9
Standard deviation 6.6
Values 41 25 33 29 27
[30]
HepG2 UBE2V1
Mean 4.65
Standard deviation 0.14
Values 4.6 4.7
[31]
HepG2.C3A UBE2V1
Mean 3.63
Standard deviation 0.17
Values 3.8 3.5
[32]
HuH.7 UBE2V1
Mean 3.85
Standard deviation 0.39
Values 4.3 3.8 3.5
[33]
SNU475 UBE2V1
Mean 3.83
Standard deviation 0.48
Values 4.2 3.5
[34]
THLE UBE2V1
Mean 2.74
Standard deviation 0.61
Values 2.3 3.2
[35]
liver UBE2V1
Mean 1.36
Standard deviation 0.64
Values 1.9 0.84 2 0.78
[36]
ref_hepatocyte IKBKG
Mean 22.7
Standard deviation 14
Values 7.4 36 37 24 10
[37]
HepG2 IKBKG
Mean 27.1
Standard deviation 5.7
Values 31 23
[38]
HepG2.C3A IKBKG
Mean 26.7
Standard deviation 4
Values 30 24
[39]
HuH.7 IKBKG
Mean 5.4
Standard deviation 1.3
Values 5.4 4.1 6.7
[40]
SNU475 IKBKG
Mean 23.2
Standard deviation 3.5
Values 21 26
[41]
THLE IKBKG
Mean 11.2
Standard deviation 1
Values 10 12
[42]
liver IKBKG
Mean 21.3
Standard deviation 6.6
Values 20 22 29 13
[43]
ref_hepatocyte IRAK1
Mean 21.3
Standard deviation 13
Values 18 30 38 16 5
[44]
HepG2 IRAK1
Mean 126
Standard deviation 40
Values 1.5e+02 97
[45]
HepG2.C3A IRAK1
Mean 73.4
Standard deviation 2.1
Values 72 75
[46]
HuH.7 IRAK1
Mean 34.7
Standard deviation 4.6
Values 40 31 34
[47]
SNU475 IRAK1
Mean 67.9
Standard deviation 14
Values 58 78
[48]
THLE IRAK1
Mean 98.2
Standard deviation 12
Values 90 1.1e+02
[49]
liver IRAK1
Mean 18.8
Standard deviation 3.7
Values 17 19 15 24
[50]
ref_hepatocyte UBE2N
Mean 19.2
Standard deviation 7.8
Values 19 28 25 11 12
[51]
HepG2 UBE2N
Mean 68.4
Standard deviation 19
Values 55 82
[52]
HepG2.C3A UBE2N
Mean 84.8
Standard deviation 36
Values 60 1.1e+02
[53]
HuH.7 UBE2N
Mean 36
Standard deviation 8.3
Values 38 27 43
[54]
SNU475 UBE2N
Mean 44
Standard deviation 3.7
Values 47 41
[55]
THLE UBE2N
Mean 45.7
Standard deviation 8
Values 40 51
[56]
liver UBE2N
Mean 16.6
Standard deviation 11
Values 25 8.3 27 5.9
[57]
ref_hepatocyte CHUK
Mean 3.93
Standard deviation 1.2
Values 4.2 5.7 2.3 3.4 4.1
[58]
HepG2 CHUK
Mean 16.2
Standard deviation 6.4
Values 12 21
[59]
HepG2.C3A CHUK
Mean 33.6
Standard deviation 13
Values 25 43
[60]
HuH.7 CHUK
Mean 31.4
Standard deviation 3.3
Values 34 28 32
[61]
SNU475 CHUK
Mean 11.3
Standard deviation 1.1
Values 11 12
[62]
THLE CHUK
Mean 22.3
Standard deviation 0.15
Values 22 22
[63]
liver CHUK
Mean 16
Standard deviation 3.3
Values 13 21 15 15
[64]
ref_hepatocyte IKBKB
Mean 3.48
Standard deviation 0.8
Values 2.9 4.3 4.2 3.5 2.5
[65]
HepG2 IKBKB
Mean 11
Standard deviation 0.46
Values 11 11
[66]
HepG2.C3A IKBKB
Mean 10.2
Standard deviation 1
Values 11 9.5
[67]
HuH.7 IKBKB
Mean 10.6
Standard deviation 1.9
Values 11 8.4 12
[68]
SNU475 IKBKB
Mean 7.65
Standard deviation 1.8
Values 8.9 6.4
[69]
THLE IKBKB
Mean 9.14
Standard deviation 0.21
Values 9.3 9
[70]
liver IKBKB
Mean 11.2
Standard deviation 0.34
Values 11 11 11 12
[71]
ref_hepatocyte PELI1
Mean 2.62
Standard deviation 1.1
Values 2.3 1.2 4.3 2.8 2.5
[72]
HepG2 PELI1
Mean 6.4
Standard deviation 0.23
Values 6.6 6.2
[73]
HepG2.C3A PELI1
Mean 10.7
Standard deviation 1.3
Values 12 9.9
[74]
HuH.7 PELI1
Mean 14.7
Standard deviation 0.52
Values 14 15 14
[75]
SNU475 PELI1
Mean 4.02
Standard deviation 0.68
Values 4.5 3.5
[76]
THLE PELI1
Mean 4.81
Standard deviation 0.64
Values 5.3 4.4
[77]
liver PELI1
Mean 9.83
Standard deviation 3.1
Values 9.2 8.2 7.6 14
[78]
ref_hepatocyte TRAF6
Mean 0.965
Standard deviation 0.32
Values 0.82 1 1.5 0.7 0.8
[79]
HepG2 TRAF6
Mean 4.54
Standard deviation 0.72
Values 4 5
[80]
HepG2.C3A TRAF6
Mean 3.74
Standard deviation 0.086
Values 3.8 3.7
[81]
HuH.7 TRAF6
Mean 5.32
Standard deviation 1
Values 5 6.4 4.5
[82]
SNU475 TRAF6
Mean 5.61
Standard deviation 0.46
Values 5.9 5.3
[83]
THLE TRAF6
Mean 4.31
Standard deviation 0.54
Values 3.9 4.7
[84]
liver TRAF6
Mean 10.3
Standard deviation 0.99
Values 9.7 12 9.8 10
[85]
ref_hepatocyte PELI3
Mean 0.716
Standard deviation 0.21
Values 0.53 0.65 0.85 1 0.54
[86]
HepG2 PELI3
Mean 4.09
Standard deviation 1.6
Values 5.2 3
[87]
HepG2.C3A PELI3
Mean 1.89
Standard deviation 0.063
Values 1.9 1.8
[88]
HuH.7 PELI3
Mean 5.26
Standard deviation 0.036
Values 5.3 5.2 5.3
[89]
SNU475 PELI3
Mean 7.34
Standard deviation 0.23
Values 7.5 7.2
[90]
THLE PELI3
Mean 6.71
Standard deviation 0.15
Values 6.6 6.8
[91]
liver PELI3
Mean 1.99
Standard deviation 0.56
Values 1.5 1.8 1.9 2.8
[92]
ref_hepatocyte PELI2
Mean 0.206
Standard deviation 0.17
Values 0 0.12 0.43 0.32 0.16
[93]
HepG2 PELI2
Mean 0.063
Standard deviation 0.089
Values 0.13 0
[94]
HepG2.C3A PELI2
Mean 0.0302
Standard deviation 0.012
Values 0.039 0.021
[95]
HuH.7 PELI2
Mean 0.0198
Standard deviation 0.028
Values 0.0082 0.051 0
[96]
SNU475 PELI2
Mean 5.94
Standard deviation 1.5
Values 7 4.9
[97]
THLE PELI2
Mean 2.76
Standard deviation 0.0023
Values 2.8 2.8
[98]
liver PELI2
Mean 3.26
Standard deviation 1
Values 1.9 4.4 3.1 3.6