REACTOME_INTRACELLULAR_SIGNALING_BY_SECOND_MESSENGERS |
Return to index |
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Order |
Gene |
Description |
ref_hepatocyte |
HepG2 |
HepG2.C3A |
HuH.7 |
SNU475 |
THLE |
liver |
1 |
UBB |
Polyubiquitin-B |
[1] |
-1.83[2] |
-2.01[3] |
-1.86[4] |
-2.17[5] |
-1.84[6] |
-1.36[7] |
2 |
RPS27A |
Ubiquitin-40S ribosomal protein S27a |
[8] |
[9] |
[10] |
[11] |
[12] |
[13] |
[14] |
3 |
UBC |
Polyubiquitin-C |
[15] |
-1.38[16] |
-1.25[17] |
-1.49[18] |
-1.31[19] |
-1.46[20] |
-0.91[21] |
4 |
PSME1 |
Proteasome activator complex subunit 1 |
[22] |
-1.15[23] |
-2.84[24] |
-2.47[25] |
-2.03[26] |
-2.68[27] |
-1.86[28] |
5 |
PSME2 |
Proteasome activator complex subunit 2 |
[29] |
-0.97[30] |
-2.46[31] |
-2.56[32] |
-1.82[33] |
-2.22[34] |
-1.48[35] |
6 |
PSMA7 |
Proteasome subunit alpha type-7 |
[36] |
-0.01[37] |
0.00[38] |
-1.31[39] |
-0.19[40] |
-0.74[41] |
-0.46[42] |
7 |
PSMB1 |
Proteasome subunit beta type-1 |
[43] |
-0.47[44] |
-0.45[45] |
-1.50[46] |
-1.43[47] |
-0.78[48] |
-0.62[49] |
8 |
PSMB3 |
Proteasome subunit beta type-3 |
[50] |
-0.95[51] |
-1.83[52] |
-0.78[53] |
-1.46[54] |
-1.69[55] |
-0.92[56] |
9 |
PSMB4 |
Proteasome subunit beta type-4 |
[57] |
-0.71[58] |
-0.63[59] |
-0.48[60] |
-0.03[61] |
-0.14[62] |
-1.25[63] |
10 |
PSMB7 |
Proteasome subunit beta type-7 |
[64] |
-1.65[65] |
-1.73[66] |
-1.58[67] |
-1.80[68] |
-1.47[69] |
-1.68[70] |
11 |
PSMB5 |
Proteasome subunit beta type-5 |
[71] |
0.75[72] |
-0.77[73] |
-0.82[74] |
-1.08[75] |
-0.91[76] |
-1.21[77] |
12 |
PSMA6 |
Proteasome subunit alpha type-6 |
[78] |
0.88[79] |
-0.49[80] |
-0.54[81] |
-0.55[82] |
-0.64[83] |
-1.13[84] |
13 |
PSMA4 |
Proteasome subunit alpha type-4 |
[85] |
-1.05[86] |
-0.47[87] |
-0.66[88] |
-0.25[89] |
-0.53[90] |
-1.21[91] |
14 |
PSMC3 |
26S proteasome regulatory subunit 6A |
[92] |
-1.09[93] |
-1.24[94] |
-0.60[95] |
-1.45[96] |
-1.36[97] |
-0.74[98] |
15 |
PSMA3 |
Proteasome subunit alpha type-3 |
[99] |
-1.67[100] |
-0.75[101] |
-1.41[102] |
-0.70[103] |
-1.26[104] |
-0.96[105] |
16 |
PSMB6 |
Proteasome subunit beta type-6 |
[106] |
-1.12[107] |
-1.06[108] |
-0.90[109] |
-1.25[110] |
-1.62[111] |
-0.80[112] |
17 |
PSMA2 |
Proteasome subunit alpha type-2 |
[113] |
-1.21[114] |
-0.33[115] |
0.02[116] |
-0.75[117] |
-0.48[118] |
-0.58[119] |
18 |
PSMD4 |
26S proteasome non-ATPase regulatory subunit 4 |
[120] |
-0.69[121] |
-0.76[122] |
-0.54[123] |
-0.05[124] |
-0.69[125] |
-0.90[126] |
19 |
PSMD7 |
26S proteasome non-ATPase regulatory subunit 7 |
[127] |
-0.77[128] |
-0.48[129] |
-0.61[130] |
-1.13[131] |
-0.77[132] |
-1.08[133] |
20 |
PSMD8 |
26S proteasome non-ATPase regulatory subunit 8 |
[134] |
-0.61[135] |
-0.45[136] |
-0.29[137] |
-0.86[138] |
-0.20[139] |
-1.05[140] |
21 |
RHEB |
GTP-binding protein Rheb |
[141] |
-1.57[142] |
-0.98[143] |
-1.06[144] |
-0.49[145] |
-0.51[146] |
-0.57[147] |
22 |
PSMD2 |
26S proteasome non-ATPase regulatory subunit 2 |
[148] |
0.92[149] |
0.02[150] |
0.11[151] |
0.25[152] |
1.44[153] |
-0.02[154] |
23 |
LAMTOR2 |
Ragulator complex protein LAMTOR2 |
[155] |
-3.04[156] |
-2.99[157] |
-3.21[158] |
-2.92[159] |
-2.85[160] |
-1.66[161] |
24 |
PSMC1 |
26S proteasome regulatory subunit 4 |
[162] |
-0.75[163] |
-0.77[164] |
-1.40[165] |
0.43[166] |
-0.15[167] |
-0.86[168] |
25 |
PSMA1 |
Proteasome subunit alpha type-1 |
[169] |
-0.57[170] |
-0.26[171] |
-0.18[172] |
0.01[173] |
-0.59[174] |
-0.37[175] |
26 |
UBA52 |
Ubiquitin-60S ribosomal protein L40 |
[176] |
1.05[177] |
0.98[178] |
2.02[179] |
0.08[180] |
0.77[181] |
-0.14[182] |
27 |
PSMC5 |
26S proteasome regulatory subunit 8 |
[183] |
-0.25[184] |
-0.44[185] |
-0.34[186] |
-0.58[187] |
-0.27[188] |
-0.60[189] |
28 |
IER3 |
Radiation-inducible immediate-early gene IEX-1 |
[190] |
0.42[191] |
0.04[192] |
-2.82[193] |
-0.52[194] |
-0.69[195] |
-4.72[196] |
29 |
RAC1 |
Ras-related C3 botulinum toxin substrate 1 |
[197] |
-0.02[198] |
-0.33[199] |
0.37[200] |
0.63[201] |
0.48[202] |
-0.45[203] |
30 |
PRKAR1A |
cAMP-dependent protein kinase type I-alpha regulatory subunit |
[204] |
0.45[205] |
0.59[206] |
0.73[207] |
0.52[208] |
0.29[209] |
1.11[210] |
31 |
PSMD3 |
26S proteasome non-ATPase regulatory subunit 3 |
[211] |
0.15[212] |
-0.44[213] |
0.17[214] |
-0.05[215] |
0.07[216] |
-0.89[217] |
32 |
PSMB8 |
Proteasome subunit beta type-8 |
[218] |
-2.25[219] |
-2.92[220] |
-10.12[221] |
-0.08[222] |
-1.49[223] |
-1.57[224] |
33 |
PSMD14 |
26S proteasome non-ATPase regulatory subunit 14 |
[225] |
-0.68[226] |
-0.15[227] |
0.12[228] |
-0.19[229] |
-0.26[230] |
-1.03[231] |
34 |
PSMC4 |
26S proteasome regulatory subunit 6B |
[232] |
-0.25[233] |
-0.30[234] |
-0.35[235] |
-0.56[236] |
-0.55[237] |
-0.55[238] |
35 |
CSNK2B |
Casein kinase II subunit beta |
[239] |
0.03[240] |
-0.12[241] |
-0.74[242] |
-0.38[243] |
-0.77[244] |
-0.99[245] |
36 |
PSMD6 |
26S proteasome non-ATPase regulatory subunit 6 |
[246] |
-1.40[247] |
-1.00[248] |
-2.07[249] |
-1.18[250] |
-0.48[251] |
-1.14[252] |
37 |
JUN |
Transcription factor AP-1 |
[253] |
-0.12[254] |
-1.64[255] |
-1.37[256] |
-1.09[257] |
-0.65[258] |
-1.29[259] |
38 |
PSMD13 |
26S proteasome non-ATPase regulatory subunit 13 |
[260] |
-0.21[261] |
-0.17[262] |
0.34[263] |
-0.12[264] |
-0.72[265] |
-0.95[266] |
39 |
CDKN1A |
Cyclin-dependent kinase inhibitor 1 |
[267] |
1.21[268] |
-0.16[269] |
-2.85[270] |
-1.37[271] |
1.05[272] |
-1.31[273] |
40 |
PSMD12 |
26S proteasome non-ATPase regulatory subunit 12 |
[274] |
-1.03[275] |
-1.03[276] |
-1.32[277] |
-0.51[278] |
-0.54[279] |
-1.03[280] |
41 |
AKT1 |
RAC-alpha serine/threonine-protein kinase |
[281] |
0.45[282] |
0.24[283] |
-0.84[284] |
0.56[285] |
0.45[286] |
0.27[287] |
42 |
STUB1 |
E3 ubiquitin-protein ligase CHIP |
[288] |
-1.61[289] |
-1.57[290] |
-2.23[291] |
-2.05[292] |
-1.85[293] |
-1.73[294] |
43 |
LAMTOR1 |
Ragulator complex protein LAMTOR1 |
[295] |
-0.25[296] |
-0.97[297] |
-1.07[298] |
-0.46[299] |
-0.64[300] |
-0.78[301] |
44 |
PSMC6 |
26S proteasome regulatory subunit 10B |
[302] |
-0.73[303] |
0.76[304] |
-0.40[305] |
-0.15[306] |
-0.32[307] |
-0.38[308] |
45 |
CSNK2A1 |
Casein kinase II subunit alpha |
[309] |
0.49[310] |
0.38[311] |
0.31[312] |
0.25[313] |
-0.24[314] |
-1.21[315] |
46 |
PSMD11 |
26S proteasome non-ATPase regulatory subunit 11 |
[316] |
0.15[317] |
-0.32[318] |
0.29[319] |
0.26[320] |
0.31[321] |
0.45[322] |
47 |
TRIB3 |
Tribbles homolog 3 |
[323] |
1.28[324] |
1.59[325] |
0.47[326] |
-1.40[327] |
-1.02[328] |
0.10[329] |
48 |
PSMC2 |
26S proteasome regulatory subunit 7 |
[330] |
-0.09[331] |
0.23[332] |
0.02[333] |
0.66[334] |
0.38[335] |
0.50[336] |
49 |
KPNA2 |
Importin subunit alpha-1 |
[337] |
1.15[338] |
1.05[339] |
1.57[340] |
1.14[341] |
1.74[342] |
-1.27[343] |
50 |
CALM1 |
Calmodulin-1 |
[344] |
0.45[345] |
0.51[346] |
0.96[347] |
2.20[348] |
1.34[349] |
2.14[350] |
51 |
PPP2R1A |
Serine/threonine-protein phosphatase
2A 65 kDa regulatory subunit A alpha isoform |
1.17[351] |
1.02[352] |
0.94[353] |
1.82[354] |
1.02[355] |
0.66[356] |
52 |
PSME3 |
Proteasome activator complex subunit 3 |
[357] |
1.13[358] |
0.77[359] |
0.47[360] |
0.68[361] |
0.84[362] |
0.07[363] |
53 |
PPP2CA |
Serine/threonine-protein phosphatase
2A catalytic subunit alpha isoform |
0.65[364] |
0.76[365] |
0.12[366] |
1.36[367] |
1.34[368] |
0.42[369] |
54 |
RRAGA |
Ras-related GTP-binding protein A |
[370] |
0.69[371] |
-0.05[372] |
-1.33[373] |
-0.42[374] |
0.05[375] |
-0.32[376] |
55 |
PPP2CB |
Serine/threonine-protein phosphatase
2A catalytic subunit beta isoform |
-0.02[377] |
-0.34[378] |
-0.27[379] |
0.16[380] |
-0.08[381] |
-0.47[382] |
56 |
RBBP7 |
Histone-binding protein RBBP7 |
[383] |
0.24[384] |
0.44[385] |
0.12[386] |
1.26[387] |
1.87[388] |
-0.15[389] |
57 |
PHC2 |
Polyhomeotic-like protein 2 |
[390] |
0.83[391] |
0.70[392] |
0.30[393] |
0.38[394] |
1.44[395] |
-0.16[396] |
58 |
PSMD1 |
26S proteasome non-ATPase regulatory subunit 1 |
[397] |
0.89[398] |
1.13[399] |
1.03[400] |
1.49[401] |
1.39[402] |
1.25[403] |
59 |
PTPN11 |
Tyrosine-protein phosphatase non-receptor type 11 |
[404] |
0.82[405] |
1.27[406] |
1.22[407] |
1.50[408] |
2.01[409] |
1.78[410] |
60 |
PSMB10 |
Proteasome subunit beta type-10 |
[411] |
-1.83[412] |
-1.32[413] |
-3.19[414] |
-0.72[415] |
-1.99[416] |
-0.90[417] |
61 |
IRAK1 |
Interleukin-1 receptor-associated kinase 1 |
[418] |
1.79[419] |
1.20[420] |
0.18[421] |
1.41[422] |
1.65[423] |
-0.17[424] |
62 |
AHCYL1 |
S-adenosylhomocysteine hydrolase-like protein 1 |
[425] |
0.61[426] |
0.73[427] |
1.29[428] |
1.63[429] |
1.37[430] |
0.82[431] |
63 |
HDAC1 |
Histone deacetylase 1 |
[432] |
0.88[433] |
0.92[434] |
1.60[435] |
1.26[436] |
0.91[437] |
0.05[438] |
64 |
GRB2 |
Growth factor receptor-bound protein 2 |
[439] |
1.57[440] |
1.43[441] |
1.54[442] |
1.17[443] |
0.95[444] |
0.82[445] |
65 |
PSMA5 |
Proteasome subunit alpha type-5 |
[446] |
1.22[447] |
1.57[448] |
1.15[449] |
1.54[450] |
1.00[451] |
1.09[452] |
66 |
PSMF1 |
Proteasome inhibitor PI31 subunit |
[453] |
1.60[454] |
1.56[455] |
0.39[456] |
0.55[457] |
0.20[458] |
1.03[459] |
67 |
MAPKAP1 |
Target of rapamycin complex 2 subunit MAPKAP1 |
[460] |
0.36[461] |
0.13[462] |
0.35[463] |
0.69[464] |
0.75[465] |
0.34[466] |
68 |
TRIM27 |
Zinc finger protein RFP |
[467] |
1.10[468] |
1.06[469] |
0.21[470] |
0.51[471] |
-0.04[472] |
0.81[473] |
69 |
MAF1 |
Repressor of RNA polymerase III transcription MAF1 homolog |
[474] |
0.55[475] |
1.07[476] |
0.42[477] |
1.00[478] |
0.16[479] |
-0.20[480] |
70 |
RPS6KB2 |
Ribosomal protein S6 kinase beta-2 |
[481] |
[482] |
[483] |
[484] |
[485] |
[486] |
[487] |
71 |
BAD |
Bcl2-associated agonist of cell death |
[488] |
-1.30[489] |
-1.15[490] |
-2.10[491] |
-0.45[492] |
-0.18[493] |
-0.90[494] |
72 |
PSMB2 |
Proteasome subunit beta type-2 |
[495] |
1.38[496] |
1.03[497] |
1.44[498] |
1.84[499] |
1.72[500] |
1.58[501] |
73 |
AKT1S1 |
Proline-rich AKT1 substrate 1 |
[502] |
-0.09[503] |
-0.22[504] |
0.12[505] |
-0.14[506] |
0.35[507] |
-0.67[508] |
74 |
PRKACA |
cAMP-dependent protein kinase catalytic subunit alpha |
[509] |
0.21[510] |
0.05[511] |
0.05[512] |
0.15[513] |
0.60[514] |
-0.26[515] |
75 |
KDM1A |
Lysine-specific histone demethylase 1A |
[516] |
1.45[517] |
2.06[518] |
1.57[519] |
1.49[520] |
0.89[521] |
-0.31[522] |
76 |
FGFR4 |
Fibroblast growth factor receptor 4 |
[523] |
2.33[524] |
2.69[525] |
3.27[526] |
-3.62[527] |
-3.88[528] |
1.02[529] |
77 |
CHD4 |
Chromodomain-helicase-DNA-binding protein 4 |
[530] |
2.41[531] |
1.96[532] |
2.01[533] |
2.60[534] |
2.33[535] |
2.09[536] |
78 |
PSMB9 |
Proteasome subunit beta type-9 |
[537] |
-2.62[538] |
-5.33[539] |
-7.62[540] |
1.09[541] |
-1.28[542] |
-1.32[543] |
79 |
PSMD9 |
26S proteasome non-ATPase regulatory subunit 9 |
[544] |
-0.24[545] |
0.17[546] |
-0.80[547] |
-0.28[548] |
0.05[549] |
-0.09[550] |
80 |
PPP2R5A |
Serine/threonine-protein phosphatase
2A 56 kDa regulatory subunit alpha isoform |
-0.75[551] |
0.16[552] |
0.88[553] |
0.36[554] |
-0.89[555] |
1.16[556] |
81 |
PPP2R5C |
Serine/threonine-protein phosphatase
2A 56 kDa regulatory subunit gamma isoform |
0.07[557] |
0.96[558] |
0.66[559] |
1.55[560] |
1.23[561] |
0.32[562] |
82 |
USP7 |
Ubiquitin carboxyl-terminal hydrolase 7 |
[563] |
1.93[564] |
1.75[565] |
1.13[566] |
0.71[567] |
0.96[568] |
1.05[569] |
83 |
CDKN1B |
Cyclin-dependent kinase inhibitor 1B |
[570] |
0.29[571] |
0.75[572] |
0.94[573] |
-0.49[574] |
-0.16[575] |
-0.39[576] |
84 |
MKRN1 |
E3 ubiquitin-protein ligase makorin-1 |
[577] |
0.60[578] |
0.32[579] |
1.08[580] |
1.02[581] |
0.37[582] |
0.63[583] |
85 |
PIK3AP1 |
Phosphoinositide 3-kinase adapter protein 1 |
[584] |
-2.41[585] |
-0.03[586] |
0.59[587] |
-2.32[588] |
-7.28[589] |
3.02[590] |
86 |
MET |
Hepatocyte growth factor receptor |
[591] |
0.46[592] |
0.51[593] |
1.13[594] |
2.15[595] |
0.74[596] |
1.49[597] |
87 |
EGR1 |
Early growth response protein 1 |
[598] |
-1.43[599] |
-0.93[600] |
-3.05[601] |
-1.72[602] |
-0.19[603] |
1.66[604] |
88 |
MTA1 |
Metastasis-associated protein MTA1 |
[605] |
0.66[606] |
0.61[607] |
0.75[608] |
0.51[609] |
0.25[610] |
-1.50[611] |
89 |
HDAC3 |
Histone deacetylase 3 |
[612] |
0.86[613] |
0.93[614] |
0.73[615] |
0.56[616] |
0.59[617] |
0.12[618] |
90 |
MTA2 |
Metastasis-associated protein MTA2 |
[619] |
1.39[620] |
0.58[621] |
0.92[622] |
1.24[623] |
1.34[624] |
0.09[625] |
91 |
MYD88 |
Myeloid differentiation primary response protein MyD88 |
[626] |
0.19[627] |
0.26[628] |
-0.31[629] |
-0.42[630] |
-0.26[631] |
1.31[632] |
92 |
PPP2R1B |
Serine/threonine-protein phosphatase
2A 65 kDa regulatory subunit A beta isoform |
0.82[633] |
0.32[634] |
0.73[635] |
0.89[636] |
0.54[637] |
3.45[638] |
93 |
MBD3 |
Methyl-CpG-binding domain protein 3 |
[639] |
0.84[640] |
1.43[641] |
0.59[642] |
0.30[643] |
1.17[644] |
0.43[645] |
94 |
IL1RAP |
Interleukin-1 receptor accessory protein |
[646] |
-1.12[647] |
1.12[648] |
0.76[649] |
-0.85[650] |
0.11[651] |
2.71[652] |
95 |
MAPK1 |
Mitogen-activated protein kinase 1 |
[653] |
2.08[654] |
2.24[655] |
2.06[656] |
2.46[657] |
1.98[658] |
2.29[659] |
96 |
RING1 |
E3 ubiquitin-protein ligase RING1 |
[660] |
0.44[661] |
0.17[662] |
-0.58[663] |
0.93[664] |
0.22[665] |
-1.66[666] |
97 |
AKT2 |
RAC-beta serine/threonine-protein kinase |
[667] |
1.33[668] |
1.63[669] |
1.75[670] |
1.47[671] |
1.13[672] |
1.65[673] |
98 |
MLST8 |
Target of rapamycin complex subunit LST8 |
[674] |
0.20[675] |
0.55[676] |
0.91[677] |
-0.36[678] |
-0.14[679] |
-0.04[680] |
99 |
KLB |
Beta-klotho |
[681] |
0.97[682] |
0.82[683] |
2.27[684] |
-5.35[685] |
-6.12[686] |
2.07[687] |
100 |
PSMD10 |
26S proteasome non-ATPase regulatory subunit 10 |
[688] |
0.31[689] |
0.55[690] |
0.59[691] |
1.39[692] |
0.61[693] |
-0.11[694] |
101 |
GSK3A |
Glycogen synthase kinase-3 alpha |
[695] |
1.00[696] |
0.76[697] |
0.85[698] |
0.69[699] |
1.33[700] |
-1.31[701] |
102 |
CAMKK2 |
Calcium/calmodulin-dependent protein kinase kinase 2 |
[702] |
0.94[703] |
1.31[704] |
0.47[705] |
0.78[706] |
0.55[707] |
1.47[708] |
103 |
ERBB3 |
Receptor tyrosine-protein kinase erbB-3 |
[709] |
2.38[710] |
3.78[711] |
2.82[712] |
-5.26[713] |
-5.14[714] |
2.83[715] |
104 |
GATAD2A |
Transcriptional repressor p66-alpha |
[716] |
1.53[717] |
0.75[718] |
2.10[719] |
0.90[720] |
1.64[721] |
0.57[722] |
105 |
PSME4 |
Proteasome activator complex subunit 4 |
[723] |
1.84[724] |
2.67[725] |
2.69[726] |
1.95[727] |
1.80[728] |
2.16[729] |
106 |
CSNK2A2 |
Casein kinase II subunit alpha' |
[730] |
0.57[731] |
0.65[732] |
0.64[733] |
0.20[734] |
0.27[735] |
-1.69[736] |
107 |
RRAGC |
Ras-related GTP-binding protein C |
[737] |
-0.18[738] |
-1.00[739] |
-0.61[740] |
0.99[741] |
0.54[742] |
-0.44[743] |
108 |
MTA3 |
Metastasis-associated protein MTA3 |
[744] |
0.90[745] |
0.62[746] |
-0.26[747] |
0.69[748] |
0.20[749] |
-1.14[750] |
109 |
PPP2R5D |
Serine/threonine-protein phosphatase
2A 56 kDa regulatory subunit delta isoform |
1.62[751] |
1.40[752] |
0.96[753] |
1.90[754] |
1.66[755] |
0.25[756] |
110 |
ATF2 |
Cyclic AMP-dependent transcription factor ATF-2 |
[757] |
1.01[758] |
2.08[759] |
2.30[760] |
1.40[761] |
1.04[762] |
1.54[763] |
111 |
FGFR3 |
Fibroblast growth factor receptor 3 |
[764] |
3.10[765] |
3.03[766] |
3.36[767] |
-2.68[768] |
-1.46[769] |
0.97[770] |
112 |
RHOG |
Rho-related GTP-binding protein RhoG |
[771] |
0.64[772] |
-0.52[773] |
-0.59[774] |
0.64[775] |
0.08[776] |
-0.18[777] |
113 |
PIK3R1 |
Phosphatidylinositol 3-kinase regulatory subunit alpha |
[778] |
-0.10[779] |
0.04[780] |
1.13[781] |
2.68[782] |
2.05[783] |
3.52[784] |
114 |
MOV10 |
Putative helicase MOV-10 |
[785] |
1.36[786] |
1.60[787] |
1.58[788] |
1.69[789] |
1.41[790] |
1.60[791] |
115 |
PRR5 |
Proline-rich protein 5 |
[792] |
-0.22[793] |
-0.14[794] |
-1.06[795] |
-1.67[796] |
-4.60[797] |
-0.26[798] |
116 |
RBBP4 |
Histone-binding protein RBBP4 |
[799] |
2.32[800] |
2.45[801] |
2.26[802] |
2.29[803] |
2.55[804] |
2.02[805] |
117 |
SLC38A9 |
Sodium-coupled neutral amino acid transporter 9 |
[806] |
-0.31[807] |
-0.05[808] |
-0.93[809] |
-0.30[810] |
-0.52[811] |
0.29[812] |
118 |
PRKAR2A |
cAMP-dependent protein kinase type II-alpha regulatory subunit |
[813] |
0.43[814] |
0.13[815] |
1.23[816] |
0.33[817] |
0.06[818] |
0.66[819] |
119 |
HDAC2 |
Histone deacetylase 2 |
[820] |
2.10[821] |
3.44[822] |
2.81[823] |
2.78[824] |
2.78[825] |
0.72[826] |
120 |
CBX4 |
E3 SUMO-protein ligase CBX4 |
[827] |
1.51[828] |
1.38[829] |
1.24[830] |
0.94[831] |
0.09[832] |
-0.89[833] |
121 |
PTEN |
Phosphatidylinositol
3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN |
-0.17[834] |
1.25[835] |
1.44[836] |
0.05[837] |
1.17[838] |
3.00[839] |
122 |
ERBB2 |
Receptor tyrosine-protein kinase erbB-2 |
[840] |
2.74[841] |
1.59[842] |
2.75[843] |
1.87[844] |
1.34[845] |
0.67[846] |
123 |
MDM2 |
E3 ubiquitin-protein ligase Mdm2 |
[847] |
2.48[848] |
3.92[849] |
1.15[850] |
1.13[851] |
1.87[852] |
2.68[853] |
124 |
PSMD5 |
26S proteasome non-ATPase regulatory subunit 5 |
[854] |
0.73[855] |
0.20[856] |
1.78[857] |
1.78[858] |
1.75[859] |
1.34[860] |
125 |
CAMK2D |
Calcium/calmodulin-dependent protein kinase type II subunit delta |
[861] |
0.51[862] |
0.83[863] |
2.35[864] |
1.29[865] |
0.35[866] |
1.93[867] |
126 |
PIP5K1A |
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha |
[868] |
1.47[869] |
1.54[870] |
1.66[871] |
2.90[872] |
2.46[873] |
0.43[874] |
127 |
PRKAR1B |
cAMP-dependent protein kinase type I-beta regulatory subunit |
[875] |
1.35[876] |
0.82[877] |
-0.98[878] |
-3.48[879] |
-0.82[880] |
0.35[881] |
128 |
ITPR2 |
Inositol 1,4,5-trisphosphate receptor type 2 |
[882] |
1.29[883] |
2.76[884] |
1.22[885] |
0.62[886] |
0.63[887] |
4.39[888] |
129 |
INSR |
Insulin receptor |
[889] |
0.83[890] |
1.50[891] |
2.93[892] |
-2.47[893] |
0.00[894] |
4.52[895] |
130 |
PPP2R5E |
Serine/threonine-protein phosphatase
2A 56 kDa regulatory subunit epsilon isoform |
0.49[896] |
0.69[897] |
0.21[898] |
1.47[899] |
1.13[900] |
0.71[901] |
131 |
EGFR |
Epidermal growth factor receptor |
[902] |
-0.32[903] |
-0.68[904] |
2.20[905] |
1.05[906] |
1.54[907] |
3.17[908] |
132 |
TP53 |
Cellular tumor antigen p53 |
[909] |
2.01[910] |
1.59[911] |
2.35[912] |
1.91[913] |
1.44[914] |
0.48[915] |
133 |
PIK3R2 |
Phosphatidylinositol 3-kinase regulatory subunit beta |
[916] |
2.25[917] |
2.49[918] |
3.10[919] |
1.32[920] |
1.75[921] |
0.23[922] |
134 |
AREG |
Amphiregulin |
[923] |
-2.49[924] |
-5.71[925] |
-7.47[926] |
-9.08[927] |
1.09[928] |
-9.79[929] |
135 |
PIP4K2C |
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma |
[930] |
1.66[931] |
1.61[932] |
0.96[933] |
1.18[934] |
1.01[935] |
0.47[936] |
136 |
RNF146 |
E3 ubiquitin-protein ligase RNF146 |
[937] |
0.32[938] |
0.81[939] |
0.04[940] |
1.22[941] |
0.79[942] |
0.97[943] |
137 |
WWP2 |
NEDD4-like E3 ubiquitin-protein ligase WWP2 |
[944] |
2.12[945] |
2.14[946] |
1.90[947] |
1.35[948] |
1.24[949] |
1.60[950] |
138 |
LAMTOR3 |
Ragulator complex protein LAMTOR3 |
[951] |
1.36[952] |
1.96[953] |
1.07[954] |
1.09[955] |
1.47[956] |
1.41[957] |
139 |
MAPK3 |
Mitogen-activated protein kinase 3 |
[958] |
2.22[959] |
2.29[960] |
2.32[961] |
1.04[962] |
0.93[963] |
-0.52[964] |
140 |
GSK3B |
Glycogen synthase kinase-3 beta |
[965] |
1.64[966] |
1.30[967] |
1.86[968] |
2.43[969] |
2.13[970] |
1.68[971] |
141 |
FGF2 |
Fibroblast growth factor 2 |
[972] |
-6.31[973] |
-6.04[974] |
-1.89[975] |
1.55[976] |
3.00[977] |
-1.15[978] |
142 |
CHUK |
Inhibitor of nuclear factor kappa-B kinase subunit alpha |
[979] |
1.28[980] |
2.52[981] |
2.47[982] |
1.26[983] |
1.95[984] |
2.03[985] |
143 |
SUZ12 |
Polycomb protein SUZ12 |
[986] |
0.88[987] |
2.09[988] |
3.14[989] |
2.64[990] |
2.56[991] |
1.66[992] |
144 |
PML |
Protein PML |
[993] |
0.61[994] |
-0.38[995] |
1.31[996] |
2.50[997] |
1.86[998] |
0.76[999] |
145 |
PIP4K2B |
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta |
[1000] |
2.91[1001] |
2.50[1002] |
2.77[1003] |
3.06[1004] |
2.23[1005] |
1.68[1006] |
146 |
RAC2 |
Ras-related C3 botulinum toxin substrate 2 |
[1007] |
-1.34[1008] |
-7.31[1009] |
-7.92[1010] |
-0.78[1011] |
2.90[1012] |
-0.71[1013] |
147 |
SRC |
Proto-oncogene tyrosine-protein kinase Src |
[1014] |
3.40[1015] |
3.40[1016] |
2.40[1017] |
3.01[1018] |
2.06[1019] |
-0.33[1020] |
148 |
PPARG |
Peroxisome proliferator-activated receptor gamma |
[1021] |
0.29[1022] |
1.92[1023] |
2.43[1024] |
1.46[1025] |
1.30[1026] |
0.14[1027] |
149 |
PRKCD |
Protein kinase C delta type |
[1028] |
1.47[1029] |
1.74[1030] |
1.21[1031] |
0.11[1032] |
1.14[1033] |
-0.55[1034] |
150 |
NEDD4 |
E3 ubiquitin-protein ligase NEDD4 |
[1035] |
-0.09[1036] |
2.01[1037] |
2.14[1038] |
1.62[1039] |
1.75[1040] |
2.72[1041] |
151 |
PDPK1 |
3-phosphoinositide-dependent protein kinase 1 |
[1042] |
2.71[1043] |
3.92[1044] |
2.62[1045] |
2.05[1046] |
2.32[1047] |
3.02[1048] |
152 |
PLCG1 |
1-phosphatidylinositol
4,5-bisphosphate phosphodiesterase gamma-1 |
3.86[1049] |
3.50[1050] |
2.83[1051] |
3.44[1052] |
2.80[1053] |
0.86[1054] |
153 |
TNKS2 |
Tankyrase-2 |
[1055] |
2.09[1056] |
3.18[1057] |
3.64[1058] |
2.74[1059] |
2.80[1060] |
2.93[1061] |
154 |
MTOR |
Serine/threonine-protein kinase mTOR |
[1062] |
2.91[1063] |
3.94[1064] |
3.50[1065] |
3.30[1066] |
3.25[1067] |
3.97[1068] |
155 |
PIP4K2A |
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha |
[1069] |
2.01[1070] |
1.30[1071] |
1.36[1072] |
2.87[1073] |
1.70[1074] |
1.82[1075] |
156 |
TSC2 |
Tuberin |
[1076] |
2.19[1077] |
1.73[1078] |
2.42[1079] |
1.82[1080] |
2.21[1081] |
2.60[1082] |
157 |
PIK3CB |
Phosphatidylinositol
4,5-bisphosphate 3-kinase catalytic subunit beta isoform |
1.58[1083] |
2.11[1084] |
2.27[1085] |
1.66[1086] |
1.69[1087] |
1.68[1088] |
158 |
IRS1 |
Insulin receptor substrate 1 |
[1089] |
2.46[1090] |
1.93[1091] |
3.35[1092] |
2.32[1093] |
1.77[1094] |
2.63[1095] |
159 |
EZH2 |
Histone-lysine N-methyltransferase EZH2 |
[1096] |
1.25[1097] |
1.95[1098] |
1.63[1099] |
2.10[1100] |
1.78[1101] |
-0.29[1102] |
160 |
ATN1 |
Atrophin-1 |
[1103] |
2.72[1104] |
2.22[1105] |
2.39[1106] |
3.13[1107] |
3.87[1108] |
0.84[1109] |
161 |
CAMK2G |
Calcium/calmodulin-dependent protein
kinase type II subunit gamma |
1.15[1110] |
2.38[1111] |
1.99[1112] |
2.30[1113] |
1.73[1114] |
1.47[1115] |
162 |
FOXO3 |
Forkhead box protein O3 |
[1116] |
0.83[1117] |
0.94[1118] |
1.57[1119] |
1.01[1120] |
2.12[1121] |
2.85[1122] |
163 |
PRKACB |
cAMP-dependent protein kinase catalytic subunit beta |
[1123] |
-0.46[1124] |
0.34[1125] |
1.62[1126] |
2.85[1127] |
1.58[1128] |
2.23[1129] |
164 |
CBX6 |
Chromobox protein homolog 6 |
[1130] |
1.25[1131] |
0.74[1132] |
0.95[1133] |
2.13[1134] |
2.48[1135] |
1.49[1136] |
165 |
TNRC6A |
Trinucleotide repeat-containing gene 6A protein |
[1137] |
2.62[1138] |
3.29[1139] |
2.47[1140] |
2.90[1141] |
2.81[1142] |
3.51[1143] |
166 |
ADCY9 |
Adenylate cyclase type 9 |
[1144] |
2.99[1145] |
2.20[1146] |
2.62[1147] |
1.57[1148] |
0.99[1149] |
2.93[1150] |
167 |
XIAP |
E3 ubiquitin-protein ligase XIAP |
[1151] |
1.89[1152] |
2.50[1153] |
2.95[1154] |
3.21[1155] |
2.50[1156] |
3.20[1157] |
168 |
SNAI2 |
Zinc finger protein SNAI2 |
[1158] |
-4.83[1159] |
-5.79[1160] |
-7.50[1161] |
0.71[1162] |
3.60[1163] |
-0.09[1164] |
169 |
CASP9 |
Caspase-9 |
[1165] |
0.53[1166] |
1.51[1167] |
0.62[1168] |
0.86[1169] |
0.05[1170] |
-0.02[1171] |
170 |
RCOR1 |
REST corepressor 1 |
[1172] |
2.16[1173] |
1.98[1174] |
2.03[1175] |
3.45[1176] |
2.50[1177] |
1.61[1178] |
171 |
CBX8 |
Chromobox protein homolog 8 |
[1179] |
0.62[1180] |
1.22[1181] |
1.00[1182] |
0.67[1183] |
-0.59[1184] |
-1.57[1185] |
172 |
EED |
Polycomb protein EED |
[1186] |
1.53[1187] |
1.16[1188] |
1.40[1189] |
2.07[1190] |
1.97[1191] |
0.72[1192] |
173 |
PRKCA |
Protein kinase C alpha type |
[1193] |
3.21[1194] |
3.27[1195] |
3.63[1196] |
2.76[1197] |
2.99[1198] |
2.44[1199] |
174 |
HDAC5 |
Histone deacetylase 5 |
[1200] |
3.06[1201] |
3.91[1202] |
3.26[1203] |
2.27[1204] |
1.53[1205] |
1.72[1206] |
175 |
RNF2 |
E3 ubiquitin-protein ligase RING2 |
[1207] |
1.14[1208] |
2.06[1209] |
1.48[1210] |
2.70[1211] |
1.04[1212] |
0.87[1213] |
176 |
PHLPP1 |
PH domain leucine-rich repeat-containing protein phosphatase 1 |
[1214] |
1.84[1215] |
1.91[1216] |
1.23[1217] |
0.56[1218] |
0.82[1219] |
2.79[1220] |
177 |
BMI1 |
Polycomb complex protein BMI-1 |
[1221] |
-2.32[1222] |
-0.55[1223] |
-1.51[1224] |
-0.35[1225] |
-0.67[1226] |
-0.97[1227] |
178 |
SCMH1 |
Polycomb protein SCMH1 |
[1228] |
1.97[1229] |
-0.59[1230] |
1.39[1231] |
1.85[1232] |
1.86[1233] |
1.61[1234] |
179 |
ITPR3 |
Inositol 1,4,5-trisphosphate receptor type 3 |
[1235] |
5.67[1236] |
4.54[1237] |
3.02[1238] |
2.97[1239] |
5.01[1240] |
0.75[1241] |
180 |
IRS2 |
Insulin receptor substrate 2 |
[1242] |
-5.28[1243] |
[1244] |
-2.41[1245] |
-0.05[1246] |
3.65[1247] |
2.90[1248] |
181 |
PPP2R5B |
Serine/threonine-protein phosphatase
2A 56 kDa regulatory subunit beta isoform |
1.15[1249] |
0.93[1250] |
0.28[1251] |
0.90[1252] |
1.94[1253] |
0.62[1254] |
182 |
FYN |
Tyrosine-protein kinase Fyn |
[1255] |
1.32[1256] |
-7.26[1257] |
1.30[1258] |
2.09[1259] |
3.48[1260] |
1.49[1261] |
183 |
TGFA |
Protransforming growth factor alpha |
[1262] |
2.17[1263] |
3.25[1264] |
-7.81[1265] |
-0.35[1266] |
-1.70[1267] |
0.13[1268] |
184 |
RPTOR |
Regulatory-associated protein of mTOR |
[1269] |
3.46[1270] |
2.71[1271] |
2.81[1272] |
2.46[1273] |
2.57[1274] |
2.86[1275] |
185 |
PIK3CA |
Phosphatidylinositol
4,5-bisphosphate 3-kinase catalytic subunit alpha isoform |
-0.01[1276] |
1.65[1277] |
1.83[1278] |
1.74[1279] |
1.82[1280] |
2.43[1281] |
186 |
PIK3CD |
Phosphatidylinositol
4,5-bisphosphate 3-kinase catalytic subunit delta isoform |
2.26[1282] |
3.37[1283] |
-0.45[1284] |
0.89[1285] |
1.53[1286] |
0.82[1287] |
187 |
RRAGD |
Ras-related GTP-binding protein D |
[1288] |
-0.64[1289] |
-4.32[1290] |
3.57[1291] |
1.73[1292] |
-0.12[1293] |
1.70[1294] |
188 |
THEM4 |
Acyl-coenzyme A thioesterase THEM4 |
[1295] |
1.02[1296] |
1.49[1297] |
2.02[1298] |
2.62[1299] |
1.91[1300] |
1.60[1301] |
189 |
ADCY6 |
Adenylate cyclase type 6 |
[1302] |
2.42[1303] |
2.91[1304] |
2.86[1305] |
3.12[1306] |
3.66[1307] |
3.15[1308] |
190 |
HBEGF |
Proheparin-binding EGF-like growth factor |
[1309] |
-0.61[1310] |
-1.40[1311] |
-2.48[1312] |
0.92[1313] |
0.48[1314] |
-1.91[1315] |
191 |
CREB1 |
Cyclic AMP-responsive element-binding protein 1 |
[1316] |
2.10[1317] |
3.27[1318] |
3.76[1319] |
3.16[1320] |
2.97[1321] |
2.86[1322] |
192 |
FOXO1 |
Forkhead box protein O1 |
[1323] |
2.07[1324] |
1.75[1325] |
1.89[1326] |
1.79[1327] |
3.68[1328] |
3.61[1329] |
193 |
REST |
RE1-silencing transcription factor |
[1330] |
1.67[1331] |
2.39[1332] |
2.55[1333] |
2.79[1334] |
2.94[1335] |
3.65[1336] |
194 |
FLT3LG |
Fms-related tyrosine kinase 3 ligand |
[1337] |
-1.88[1338] |
-1.77[1339] |
-1.31[1340] |
-1.72[1341] |
-0.76[1342] |
-1.64[1343] |
195 |
PHC1 |
Polyhomeotic-like protein 1 |
[1344] |
1.90[1345] |
1.04[1346] |
1.19[1347] |
1.37[1348] |
2.24[1349] |
0.70[1350] |
196 |
RRAGB |
Ras-related GTP-binding protein B |
[1351] |
0.10[1352] |
0.68[1353] |
-8.79[1354] |
1.06[1355] |
0.75[1356] |
1.11[1357] |
197 |
PDGFA |
Platelet-derived growth factor subunit A |
[1358] |
-0.63[1359] |
-0.40[1360] |
1.68[1361] |
0.27[1362] |
-0.77[1363] |
-0.23[1364] |
198 |
RICTOR |
Rapamycin-insensitive companion of mTOR |
[1365] |
1.10[1366] |
3.20[1367] |
3.87[1368] |
2.97[1369] |
3.04[1370] |
4.03[1371] |
199 |
GAB2 |
GRB2-associated-binding protein 2 |
[1372] |
1.94[1373] |
1.75[1374] |
1.99[1375] |
1.54[1376] |
1.49[1377] |
1.06[1378] |
200 |
FOXO4 |
Forkhead box protein O4 |
[1379] |
1.10[1380] |
1.52[1381] |
1.35[1382] |
0.78[1383] |
0.86[1384] |
-0.17[1385] |
201 |
ESR1 |
Estrogen receptor |
[1386] |
-6.93[1387] |
[1388] |
-5.40[1389] |
-3.55[1390] |
-5.95[1391] |
2.92[1392] |
202 |
USP13 |
Ubiquitin carboxyl-terminal hydrolase 13 |
[1393] |
2.53[1394] |
4.20[1395] |
2.99[1396] |
2.58[1397] |
2.59[1398] |
2.63[1399] |
203 |
HDAC7 |
Histone deacetylase 7 |
[1400] |
2.76[1401] |
2.13[1402] |
1.82[1403] |
3.72[1404] |
3.91[1405] |
1.50[1406] |
204 |
TNKS |
Tankyrase-1 |
[1407] |
3.10[1408] |
3.45[1409] |
4.42[1410] |
2.22[1411] |
3.12[1412] |
3.72[1413] |
205 |
IRAK4 |
Interleukin-1 receptor-associated kinase 4 |
[1414] |
0.63[1415] |
2.01[1416] |
2.29[1417] |
2.03[1418] |
1.66[1419] |
2.30[1420] |
206 |
FGFR2 |
Fibroblast growth factor receptor 2 |
[1421] |
-2.14[1422] |
-0.91[1423] |
3.03[1424] |
2.07[1425] |
-2.90[1426] |
3.94[1427] |
207 |
GATAD2B |
Transcriptional repressor p66-beta |
[1428] |
2.01[1429] |
1.65[1430] |
3.07[1431] |
3.39[1432] |
3.06[1433] |
2.64[1434] |
208 |
FRK |
Tyrosine-protein kinase FRK |
[1435] |
0.81[1436] |
1.48[1437] |
1.93[1438] |
1.71[1439] |
-0.87[1440] |
3.50[1441] |
209 |
PHC3 |
Polyhomeotic-like protein 3 |
[1442] |
2.09[1443] |
3.32[1444] |
4.51[1445] |
3.24[1446] |
3.61[1447] |
4.78[1448] |
210 |
NRG1 |
Pro-neuregulin-1, membrane-bound isoform |
[1449] |
0.71[1450] |
-5.41[1451] |
-2.52[1452] |
2.67[1453] |
-4.94[1454] |
1.29[1455] |
211 |
FRS2 |
Fibroblast growth factor receptor substrate 2 |
[1456] |
1.66[1457] |
2.78[1458] |
3.27[1459] |
3.52[1460] |
3.01[1461] |
3.86[1462] |
212 |
IL1RL1 |
Interleukin-1 receptor-like 1 |
[1463] |
-4.98[1464] |
-3.72[1465] |
-5.28[1466] |
-4.70[1467] |
6.54[1468] |
1.88[1469] |
213 |
STRN |
Striatin |
[1470] |
2.34[1471] |
3.32[1472] |
2.94[1473] |
3.94[1474] |
3.70[1475] |
3.42[1476] |
214 |
PIP5K1C |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma |
[1477] |
3.14[1478] |
2.40[1479] |
2.72[1480] |
3.24[1481] |
3.67[1482] |
1.98[1483] |
215 |
OTUD3 |
OTU domain-containing protein 3 |
[1484] |
2.35[1485] |
3.27[1486] |
2.20[1487] |
3.05[1488] |
2.49[1489] |
1.39[1490] |
216 |
NR4A1 |
Nuclear receptor subfamily 4 group A member 1 |
[1491] |
1.59[1492] |
2.16[1493] |
2.29[1494] |
0.76[1495] |
1.72[1496] |
1.05[1497] |
217 |
TRAF6 |
TNF receptor-associated factor 6 |
[1498] |
1.46[1499] |
1.37[1500] |
1.93[1501] |
2.28[1502] |
1.60[1503] |
3.43[1504] |
218 |
BTC |
Probetacellulin |
[1505] |
-7.77[1506] |
-8.14[1507] |
-3.92[1508] |
-2.26[1509] |
-2.42[1510] |
-2.40[1511] |
219 |
TNRC6B |
Trinucleotide repeat-containing gene 6B protein |
[1512] |
2.60[1513] |
2.83[1514] |
4.50[1515] |
3.33[1516] |
3.17[1517] |
5.86[1518] |
220 |
PHLPP2 |
PH domain leucine-rich repeat-containing protein phosphatase 2 |
[1519] |
2.70[1520] |
3.32[1521] |
2.85[1522] |
3.81[1523] |
2.98[1524] |
2.93[1525] |
221 |
FGFR1 |
Fibroblast growth factor receptor 1 |
[1526] |
4.95[1527] |
3.28[1528] |
4.93[1529] |
5.67[1530] |
4.81[1531] |
2.18[1532] |
222 |
CBX2 |
Chromobox protein homolog 2 |
[1533] |
3.71[1534] |
3.66[1535] |
4.62[1536] |
3.32[1537] |
2.16[1538] |
-0.35[1539] |
223 |
GAB1 |
GRB2-associated-binding protein 1 |
[1540] |
1.67[1541] |
2.78[1542] |
2.90[1543] |
2.55[1544] |
2.28[1545] |
3.39[1546] |
224 |
ADCY1 |
Adenylate cyclase type 1 |
[1547] |
-0.46[1548] |
-2.31[1549] |
-2.52[1550] |
-1.49[1551] |
-1.64[1552] |
5.51[1553] |
225 |
PDGFB |
Platelet-derived growth factor subunit B |
[1554] |
3.43[1555] |
3.31[1556] |
0.50[1557] |
0.68[1558] |
0.12[1559] |
0.89[1560] |
226 |
PRKCE |
Protein kinase C epsilon type |
[1561] |
1.02[1562] |
-0.48[1563] |
2.01[1564] |
1.60[1565] |
1.83[1566] |
4.08[1567] |
227 |
PIP5K1B |
Phosphatidylinositol 4-phosphate 5-kinase type-1 beta |
[1568] |
0.81[1569] |
3.24[1570] |
2.77[1571] |
-3.21[1572] |
-4.93[1573] |
-2.37[1574] |
228 |
CHD3 |
Chromodomain-helicase-DNA-binding protein 3 |
[1575] |
3.17[1576] |
3.80[1577] |
5.92[1578] |
6.91[1579] |
5.95[1580] |
3.04[1581] |
229 |
PRKX |
cAMP-dependent protein kinase catalytic subunit PRKX |
[1582] |
-1.27[1583] |
-1.48[1584] |
3.44[1585] |
1.87[1586] |
3.27[1587] |
1.96[1588] |
230 |
CAMK2B |
Calcium/calmodulin-dependent protein kinase type II subunit beta |
[1589] |
-2.16[1590] |
-3.47[1591] |
-6.43[1592] |
-2.25[1593] |
-1.74[1594] |
1.67[1595] |
231 |
NRG4 |
Pro-neuregulin-4, membrane-bound isoform |
[1596] |
-3.72[1597] |
-0.82[1598] |
-0.88[1599] |
0.90[1600] |
-1.43[1601] |
-0.42[1602] |
232 |
FGF7 |
Fibroblast growth factor 7 |
[1603] |
-8.92[1604] |
-5.20[1605] |
[1606] |
-4.76[1607] |
-0.62[1608] |
-0.93[1609] |
233 |
ADCY7 |
Adenylate cyclase type 7 |
[1610] |
3.89[1611] |
3.53[1612] |
2.48[1613] |
3.92[1614] |
3.27[1615] |
3.44[1616] |
234 |
PDGFRA |
Platelet-derived growth factor receptor alpha |
[1617] |
-3.25[1618] |
-4.21[1619] |
3.42[1620] |
1.14[1621] |
5.68[1622] |
5.84[1623] |
235 |
PDGFRB |
Platelet-derived growth factor receptor beta |
[1624] |
1.67[1625] |
2.09[1626] |
-0.37[1627] |
2.47[1628] |
2.90[1629] |
3.93[1630] |
236 |
TNRC6C |
Trinucleotide repeat-containing gene 6C protein |
[1631] |
2.46[1632] |
2.43[1633] |
2.71[1634] |
1.38[1635] |
1.23[1636] |
3.82[1637] |
237 |
VAV1 |
Proto-oncogene vav |
[1638] |
-8.12[1639] |
-3.28[1640] |
-4.99[1641] |
-5.47[1642] |
-6.87[1643] |
1.70[1644] |
238 |
IL33 |
Interleukin-33 |
[1645] |
-2.56[1646] |
-7.11[1647] |
0.62[1648] |
-2.56[1649] |
6.39[1650] |
5.18[1651] |
239 |
PIK3R3 |
Phosphatidylinositol 3-kinase regulatory subunit gamma |
[1652] |
2.10[1653] |
2.12[1654] |
2.97[1655] |
3.78[1656] |
2.67[1657] |
3.20[1658] |
240 |
ITPR1 |
Inositol 1,4,5-trisphosphate receptor type 1 |
[1659] |
3.51[1660] |
3.42[1661] |
4.56[1662] |
3.47[1663] |
4.20[1664] |
5.17[1665] |
241 |
CD86 |
T-lymphocyte activation antigen CD86 |
[1666] |
[1667] |
[1668] |
-4.32[1669] |
-3.48[1670] |
-5.63[1671] |
1.87[1672] |
242 |
AKT3 |
RAC-gamma serine/threonine-protein kinase |
[1673] |
-1.47[1674] |
-4.01[1675] |
-3.32[1676] |
6.46[1677] |
5.28[1678] |
4.13[1679] |
243 |
LCK |
Tyrosine-protein kinase Lck |
[1680] |
3.15[1681] |
3.25[1682] |
-6.75[1683] |
-4.47[1684] |
-4.80[1685] |
1.75[1686] |
244 |
CAMKK1 |
Calcium/calmodulin-dependent protein kinase kinase 1 |
[1687] |
1.62[1688] |
0.94[1689] |
-0.77[1690] |
3.46[1691] |
1.77[1692] |
0.61[1693] |
245 |
KL |
Klotho |
[1694] |
-5.68[1695] |
[1696] |
[1697] |
-0.78[1698] |
-6.16[1699] |
0.77[1700] |
246 |
FGF5 |
Fibroblast growth factor 5 |
[1701] |
-0.62[1702] |
0.72[1703] |
0.64[1704] |
2.10[1705] |
1.65[1706] |
3.65[1707] |
247 |
EREG |
Proepiregulin |
[1708] |
2.13[1709] |
2.07[1710] |
-2.35[1711] |
-0.95[1712] |
4.17[1713] |
-0.96[1714] |
248 |
MECOM |
MDS1 and EVI1 complex locus protein EVI1 |
[1715] |
-0.76[1716] |
-2.50[1717] |
6.17[1718] |
2.18[1719] |
4.47[1720] |
3.19[1721] |
249 |
SNAI1 |
Zinc finger protein SNAI1 |
[1722] |
3.44[1723] |
1.78[1724] |
3.84[1725] |
3.63[1726] |
2.79[1727] |
1.57[1728] |
250 |
SALL4 |
Sal-like protein 4 |
[1729] |
0.38[1730] |
-1.37[1731] |
4.21[1732] |
-0.11[1733] |
0.15[1734] |
1.70[1735] |
251 |
FGF1 |
Fibroblast growth factor 1 |
[1736] |
-2.39[1737] |
-1.58[1738] |
-6.05[1739] |
1.20[1740] |
2.65[1741] |
0.56[1742] |
252 |
FGF19 |
Fibroblast growth factor 19 |
[1743] |
-1.69[1744] |
-0.52[1745] |
6.22[1746] |
1.44[1747] |
-2.15[1748] |
[1749] |
253 |
PRKAR2B |
cAMP-dependent protein kinase type II-beta regulatory subunit |
[1750] |
-1.97[1751] |
-0.12[1752] |
4.16[1753] |
5.70[1754] |
4.08[1755] |
3.83[1756] |
254 |
ADCY3 |
Adenylate cyclase type 3 |
[1757] |
1.83[1758] |
0.61[1759] |
3.93[1760] |
5.35[1761] |
6.75[1762] |
4.03[1763] |
255 |
KITLG |
Kit ligand |
[1764] |
5.82[1765] |
2.06[1766] |
7.78[1767] |
7.34[1768] |
5.41[1769] |
3.56[1770] |
256 |
CD28 |
T-cell-specific surface glycoprotein CD28 |
[1771] |
-3.63[1772] |
-2.74[1773] |
-2.71[1774] |
-1.73[1775] |
-1.92[1776] |
1.64[1777] |
257 |
ADCY2 |
Adenylate cyclase type 2 |
[1778] |
-5.01[1779] |
-3.06[1780] |
-4.32[1781] |
-2.12[1782] |
-3.37[1783] |
-3.60[1784] |
258 |
KIT |
Mast/stem cell growth factor receptor Kit |
[1785] |
-2.62[1786] |
-4.48[1787] |
[1788] |
3.12[1789] |
-2.55[1790] |
4.16[1791] |
259 |
NBEA |
Neurobeachin |
[1792] |
4.36[1793] |
4.07[1794] |
1.86[1795] |
2.55[1796] |
4.77[1797] |
5.34[1798] |
260 |
CD19 |
B-lymphocyte antigen CD19 |
[1799] |
2.48[1800] |
4.20[1801] |
-0.64[1802] |
-0.85[1803] |
[1804] |
1.58[1805] |
261 |
PDE1B |
Calcium/calmodulin-dependent
3',5'-cyclic nucleotide phosphodiesterase 1B |
-3.31[1806] |
-4.26[1807] |
[1808] |
-0.20[1809] |
-1.42[1810] |
4.38[1811] |
262 |
CD80 |
T-lymphocyte activation antigen CD80 |
[1812] |
[1813] |
[1814] |
-4.87[1815] |
-0.54[1816] |
-1.73[1817] |
3.14[1818] |
263 |
FLT3 |
Receptor-type tyrosine-protein kinase FLT3 |
[1819] |
[1820] |
[1821] |
-3.11[1822] |
-2.18[1823] |
[1824] |
3.44[1825] |
264 |
ESR2 |
Estrogen receptor beta |
[1826] |
-0.19[1827] |
0.20[1828] |
0.22[1829] |
1.25[1830] |
1.21[1831] |
3.05[1832] |
265 |
ADCY5 |
Adenylate cyclase type 5 |
[1833] |
0.53[1834] |
1.54[1835] |
2.57[1836] |
1.27[1837] |
2.26[1838] |
6.89[1839] |
266 |
PRKCG |
Protein kinase C gamma type |
[1840] |
-0.45[1841] |
0.25[1842] |
-2.14[1843] |
-0.45[1844] |
-0.67[1845] |
[1846] |
267 |
TRAT1 |
T-cell receptor-associated transmembrane adapter 1 |
[1847] |
[1848] |
[1849] |
[1850] |
[1851] |
[1852] |
3.31[1853] |
268 |
ICOS |
Inducible T-cell costimulator |
[1854] |
[1855] |
-2.98[1856] |
[1857] |
[1858] |
[1859] |
-0.04[1860] |
269 |
CAMK4 |
Calcium/calmodulin-dependent protein kinase type IV |
[1861] |
[1862] |
-1.37[1863] |
-2.04[1864] |
2.06[1865] |
3.99[1866] |
4.76[1867] |
270 |
PREX2 |
Phosphatidylinositol
3,4,5-trisphosphate-dependent Rac exchanger 2 protein |
-3.04[1868] |
-2.95[1869] |
4.16[1870] |
3.21[1871] |
[1872] |
7.43[1873] |
271 |
HGF |
Hepatocyte growth factor |
[1874] |
[1875] |
[1876] |
-1.26[1877] |
5.21[1878] |
2.11[1879] |
9.41[1880] |
272 |
FGF8 |
Fibroblast growth factor 8 |
[1881] |
-2.95[1882] |
-2.59[1883] |
1.90[1884] |
-1.30[1885] |
[1886] |
3.21[1887] |
273 |
PDE1A |
Calcium/calmodulin-dependent
3',5'-cyclic nucleotide phosphodiesterase 1A |
[1888] |
-0.32[1889] |
4.37[1890] |
6.73[1891] |
3.06[1892] |
7.12[1893] |
274 |
NR2E1 |
Nuclear receptor subfamily 2 group E member 1 |
[1894] |
-3.62[1895] |
[1896] |
0.86[1897] |
2.72[1898] |
-2.95[1899] |
1.43[1900] |
275 |
FGF18 |
Fibroblast growth factor 18 |
[1901] |
2.15[1902] |
-1.95[1903] |
0.22[1904] |
1.23[1905] |
1.69[1906] |
1.10[1907] |
276 |
FGF9 |
Fibroblast growth factor 9 |
[1908] |
2.63[1909] |
-1.00[1910] |
[1911] |
3.40[1912] |
-1.85[1913] |
0.62[1914] |
277 |
ADCY4 |
Adenylate cyclase type 4 |
[1915] |
0.46[1916] |
-0.59[1917] |
2.05[1918] |
[1919] |
[1920] |
8.89[1921] |
278 |
EGF |
Pro-epidermal growth factor |
[1922] |
2.34[1923] |
4.15[1924] |
7.76[1925] |
9.64[1926] |
6.93[1927] |
2.10[1928] |
279 |
ERBB4 |
Receptor tyrosine-protein kinase erbB-4 |
[1929] |
[1930] |
[1931] |
[1932] |
[1933] |
[1934] |
[1935] |
280 |
FGF16 |
Fibroblast growth factor 16 |
[1936] |
[1937] |
[1938] |
[1939] |
[1940] |
[1941] |
[1942] |
281 |
PRKACG |
cAMP-dependent protein kinase catalytic subunit gamma |
[1943] |
[1944] |
[1945] |
[1946] |
[1947] |
[1948] |
[1949] |
282 |
PSMA8 |
Proteasome subunit alpha type-7-like |
[1950] |
[1951] |
[1952] |
[1953] |
[1954] |
[1955] |
[1956] |
283 |
PDE1C |
Calcium/calmodulin-dependent
3',5'-cyclic nucleotide phosphodiesterase 1C |
[1957] |
[1958] |
[1959] |
[1960] |
[1961] |
[1962] |
284 |
AGO3 |
Protein argonaute-3 |
[1963] |
[1964] |
[1965] |
[1966] |
[1967] |
[1968] |
[1969] |
285 |
GRK2 |
Beta-adrenergic receptor kinase 1 |
[1970] |
[1971] |
[1972] |
[1973] |
[1974] |
[1975] |
[1976] |
286 |
NRG3 |
Pro-neuregulin-3, membrane-bound isoform |
[1977] |
[1978] |
[1979] |
[1980] |
[1981] |
[1982] |
[1983] |
287 |
FGF4 |
Fibroblast growth factor 4 |
[1984] |
[1985] |
[1986] |
[1987] |
[1988] |
[1989] |
[1990] |
288 |
FGF10 |
Fibroblast growth factor 10 |
[1991] |
[1992] |
[1993] |
[1994] |
[1995] |
[1996] |
[1997] |
289 |
FGF22 |
Fibroblast growth factor 22 |
[1998] |
[1999] |
[2000] |
[2001] |
[2002] |
[2003] |
[2004] |
290 |
FGF17 |
Fibroblast growth factor 17 |
[2005] |
[2006] |
[2007] |
[2008] |
[2009] |
[2010] |
[2011] |
291 |
FGF3 |
Fibroblast growth factor 3 |
[2012] |
[2013] |
[2014] |
[2015] |
[2016] |
[2017] |
[2018] |
292 |
LAMTOR5 |
Ragulator complex protein LAMTOR5 |
[2019] |
[2020] |
[2021] |
[2022] |
[2023] |
[2024] |
[2025] |
293 |
AGO4 |
Protein argonaute-4 |
[2026] |
[2027] |
[2028] |
[2029] |
[2030] |
[2031] |
[2032] |
294 |
LAMTOR4 |
Ragulator complex protein LAMTOR4 |
[2033] |
[2034] |
[2035] |
[2036] |
[2037] |
[2038] |
[2039] |
295 |
SEM1 |
Putative protein SEM1, isoform 2 |
[2040] |
[2041] |
[2042] |
[2043] |
[2044] |
[2045] |
[2046] |
296 |
FGF23 |
Fibroblast growth factor 23 |
[2047] |
[2048] |
[2049] |
[2050] |
[2051] |
[2052] |
[2053] |
297 |
FGF20 |
Fibroblast growth factor 20 |
[2054] |
[2055] |
[2056] |
[2057] |
[2058] |
[2059] |
[2060] |
298 |
FOXO6 |
Forkhead box protein O6 |
[2061] |
[2062] |
[2063] |
[2064] |
[2065] |
[2066] |
[2067] |
299 |
FGF6 |
Fibroblast growth factor 6 |
[2068] |
[2069] |
[2070] |
[2071] |
[2072] |
[2073] |
[2074] |
300 |
PSMB11 |
Proteasome subunit beta type-11 |
[2075] |
[2076] |
[2077] |
[2078] |
[2079] |
[2080] |
[2081] |
301 |
AGO2 |
Protein argonaute-2 |
[2082] |
[2083] |
[2084] |
[2085] |
[2086] |
[2087] |
[2088] |
302 |
CAMK2A |
Calcium/calmodulin-dependent protein kinase type II subunit alpha |
[2089] |
[2090] |
[2091] |
[2092] |
[2093] |
[2094] |
[2095] |
303 |
NRG2 |
Pro-neuregulin-2, membrane-bound isoform |
[2096] |
[2097] |
[2098] |
[2099] |
[2100] |
[2101] |
[2102] |
304 |
AGO1 |
Protein argonaute-1 |
[2103] |
[2104] |
[2105] |
[2106] |
[2107] |
[2108] |
[2109] |
305 |
EPGN |
Epigen |
[2110] |
[2111] |
[2112] |
[2113] |
[2114] |
[2115] |
[2116] |
306 |
ADCY8 |
Adenylate cyclase type 8 |
[2117] |
[2118] |
[2119] |
[2120] |
[2121] |
[2122] |
[2123] |
307 |
INS |
Insulin |
[2124] |
[2125] |
[2126] |
[2127] |
[2128] |
[2129] |
[2130] |
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