REACTOME_INTERLEUKIN_3_INTERLEUKIN_5_AND_GM_CSF_SIGNALING Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 UBB Polyubiquitin-B [1] -0.85[2] -1.08[3] -1.13[4] -1.70[5] -1.02[6] -0.59[7]
2 RPS27A Ubiquitin-40S ribosomal protein S27a [8] [9] [10] [11] [12] [13] [14]
3 UBC Polyubiquitin-C [15] -0.41[16] -0.33[17] -0.76[18] -0.84[19] -0.65[20] -0.14[21]
4 YWHAZ 14-3-3 protein zeta/delta [22] 0.77[23] 0.59[24] 0.72[25] 1.99[26] 0.78[27] -0.36[28]
5 UBA52 Ubiquitin-60S ribosomal protein L40 [29] 2.03[30] 1.91[31] 2.75[32] 0.55[33] 1.58[34] 0.63[35]
6 PTPN11 Tyrosine-protein phosphatase non-receptor type 11 [36] 1.79[37] 2.20[38] 1.95[39] 1.97[40] 2.82[41] 2.54[42]
7 GRB2 Growth factor receptor-bound protein 2 [43] 2.54[44] 2.35[45] 2.28[46] 1.64[47] 1.76[48] 1.58[49]
8 YES1 Tyrosine-protein kinase Yes [50] 0.49[51] 1.95[52] 1.97[53] 1.53[54] 1.21[55] 1.41[56]
9 CRK Adapter molecule crk [57] 1.14[58] 1.05[59] 0.92[60] 0.84[61] 1.45[62] 2.13[63]
10 SHC1 SHC-transforming protein 1 [64] 2.51[65] 2.70[66] 2.58[67] 3.74[68] 3.43[69] 2.06[70]
11 PRKACA cAMP-dependent protein kinase catalytic subunit alpha [71] 1.18[72] 0.98[73] 0.78[74] 0.62[75] 1.42[76] 0.51[77]
12 JAK1 Tyrosine-protein kinase JAK1 [78] 1.86[79] 1.32[80] 1.30[81] 1.71[82] 2.57[83] 2.82[84]
13 CRKL Crk-like protein [85] 3.05[86] 3.12[87] 3.53[88] 2.21[89] 2.62[90] 2.74[91]
14 PIK3R1 Phosphatidylinositol 3-kinase regulatory subunit alpha [92] 0.87[93] 0.97[94] 1.86[95] 3.15[96] 2.86[97] 4.29[98]
15 SOS1 Son of sevenless homolog 1 [99] 1.25[100] 2.75[101] 2.06[102] 1.93[103] 1.37[104] 1.82[105]
16 BLNK B-cell linker protein [106] -8.25[107] -8.42[108] -6.28[109] -9.21[110] -7.56[111] 1.21[112]
17 LYN Tyrosine-protein kinase Lyn [113] 0.48[114] 0.28[115] 0.61[116] 2.14[117] 1.11[118] 1.30[119]
18 PTPN6 Tyrosine-protein phosphatase non-receptor type 6 [120] 0.88[121] 1.05[122] 1.43[123] -6.05[124] -0.83[125] 1.11[126]
19 PIK3R2 Phosphatidylinositol 3-kinase regulatory subunit beta [127] 3.22[128] 3.42[129] 3.83[130] 1.79[131] 2.56[132] 0.99[133]
20 RAPGEF1 Rap guanine nucleotide exchange factor 1 [134] 3.43[135] 3.24[136] 2.76[137] 2.34[138] 2.22[139] 2.46[140]
21 STAT5B Signal transducer and activator of transcription 5B [141] 2.70[142] 2.30[143] 2.81[144] 2.64[145] 1.99[146] 2.91[147]
22 INPPL1 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 [148] 3.48[149] 2.72[150] 3.27[151] 4.41[152] 3.90[153] 2.25[154]
23 PIK3CB Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 2.56[155] 3.04[156] 3.00[157] 2.13[158] 2.50[159] 2.44[160]
24 STAT5A Signal transducer and activator of transcription 5A [161] -0.60[162] 0.55[163] -0.58[164] 0.24[165] 1.21[166] 1.52[167]
25 FYN Tyrosine-protein kinase Fyn [168] 2.29[169] -6.34[170] 2.03[171] 2.56[172] 4.29[173] 2.25[174]
26 PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 0.97[175] 2.58[176] 2.57[177] 2.21[178] 2.63[179] 3.20[180]
27 PIK3CD Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 3.23[181] 4.29[182] 0.28[183] 1.36[184] 2.34[185] 1.58[186]
28 GAB2 GRB2-associated-binding protein 2 [187] 2.91[188] 2.67[189] 2.72[190] 2.01[191] 2.31[192] 1.83[193]
29 HCK Tyrosine-protein kinase HCK [194] -4.50[195] -4.71[196] [197] -4.18[198] -4.91[199] 1.99[200]
30 INPP5D Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 [201] 5.20[202] 5.56[203] -4.83[204] -4.58[205] -1.42[206] 2.56[207]
31 IL2RG Cytokine receptor common subunit gamma [208] -0.30[209] -2.22[210] -1.77[211] -2.51[212] [213] 1.18[214]
32 JAK2 Tyrosine-protein kinase JAK2 [215] 1.57[216] 1.54[217] 0.90[218] 1.85[219] 2.65[220] 3.99[221]
33 TEC Tyrosine-protein kinase Tec [222] -0.81[223] -1.23[224] -0.84[225] 2.43[226] 1.06[227] 2.88[228]
34 CBL E3 ubiquitin-protein ligase CBL [229] 5.79[230] 4.71[231] 4.74[232] 6.22[233] 5.91[234] 5.04[235]
35 VAV1 Proto-oncogene vav [236] -7.15[237] -2.35[238] -4.26[239] -5.00[240] -6.05[241] 2.47[242]
36 CSF2RA Granulocyte-macrophage colony-stimulating factor receptor subunit alpha [243] [244] [245] [246] [247] -5.18[248]
37 IL2RB Interleukin-2 receptor subunit beta [249] -3.42[250] -4.01[251] -5.18[252] -1.73[253] -3.94[254] 2.83[255]
38 PIK3R3 Phosphatidylinositol 3-kinase regulatory subunit gamma [256] 3.07[257] 3.05[258] 3.70[259] 4.25[260] 3.48[261] 3.96[262]
39 SYK Tyrosine-protein kinase SYK [263] -6.82[264] -0.97[265] -4.19[266] 1.18[267] -2.12[268] 4.65[269]
40 IL3RA Interleukin-3 receptor subunit alpha [270] [271] [272] [273] [274] [275] [276]
41 JAK3 Tyrosine-protein kinase JAK3 [277] 3.59[278] 5.84[279] -0.37[280] 0.45[281] 1.40[282] 4.38[283]
42 CSF2RB Cytokine receptor common subunit beta [284] [285] [286] [287] -5.06[288] -2.54[289] 4.15[290]
43 IL2RA Interleukin-2 receptor subunit alpha [291] [292] -4.27[293] [294] -3.52[295] -5.22[296] 1.82[297]
44 CSF2 Granulocyte-macrophage colony-stimulating factor [298] 1.81[299] -2.17[300] -1.73[301] -0.63[302] 7.48[303] -0.19[304]
45 IL5RA Interleukin-5 receptor subunit alpha [305] [306] [307] [308] 0.50[309] 0.80[310] 3.62[311]
46 IL2 Interleukin-2 [312] [313] [314] [315] [316] [317] [318]
47 IL3 Interleukin-3 [319] [320] [321] [322] [323] [324] [325]
48 IL5 Interleukin-5 [326] [327] [328] [329] [330] [331] [332]
[1]
ref_hepatocyte UBB
Mean 764
Standard deviation 4.8e+02
Values 3.8e+02 3.5e+02 5.3e+02 1.2e+03 1.3e+03
[2]
HepG2 UBB
Mean 368
Standard deviation 39
Values 4e+02 3.4e+02
[3]
HepG2.C3A UBB
Mean 285
Standard deviation 14
Values 2.8e+02 3e+02
[4]
HuH.7 UBB
Mean 304
Standard deviation 40
Values 2.9e+02 2.7e+02 3.5e+02
[5]
SNU475 UBB
Mean 204
Standard deviation 3.3
Values 2.1e+02 2e+02
[6]
THLE UBB
Mean 315
Standard deviation 34
Values 2.9e+02 3.4e+02
[7]
liver UBB
Mean 296
Standard deviation 1.3e+02
Values 4.3e+02 2.1e+02 3.9e+02 1.5e+02
[8]
ref_hepatocyte RPS27A
Mean 499
Standard deviation 2.2e+02
Values 6.6e+02 6.1e+02 1.7e+02 6.8e+02 3.8e+02
[9]
HepG2 RPS27A
Missing
[10]
HepG2.C3A RPS27A
Missing
[11]
HuH.7 RPS27A
Missing
[12]
SNU475 RPS27A
Missing
[13]
THLE RPS27A
Missing
[14]
liver RPS27A
Missing
[15]
ref_hepatocyte UBC
Mean 480
Standard deviation 2.8e+02
Values 1.8e+02 3.5e+02 9.1e+02 5.8e+02 3.8e+02
[16]
HepG2 UBC
Mean 314
Standard deviation 38
Values 3.4e+02 2.9e+02
[17]
HepG2.C3A UBC
Mean 302
Standard deviation 41
Values 3.3e+02 2.7e+02
[18]
HuH.7 UBC
Mean 246
Standard deviation 64
Values 2.4e+02 3.1e+02 1.9e+02
[19]
SNU475 UBC
Mean 232
Standard deviation 63
Values 2.8e+02 1.9e+02
[20]
THLE UBC
Mean 257
Standard deviation 41
Values 2.3e+02 2.9e+02
[21]
liver UBC
Mean 254
Standard deviation 78
Values 2.2e+02 3.1e+02 3.3e+02 1.6e+02
[22]
ref_hepatocyte YWHAZ
Mean 161
Standard deviation 1.6e+02
Values 1.3e+02 4.3e+02 1.6e+02 40 41
[23]
HepG2 YWHAZ
Mean 239
Standard deviation 21
Values 2.2e+02 2.5e+02
[24]
HepG2.C3A YWHAZ
Mean 191
Standard deviation 28
Values 1.7e+02 2.1e+02
[25]
HuH.7 YWHAZ
Mean 229
Standard deviation 23
Values 2.5e+02 2.1e+02 2.3e+02
[26]
SNU475 YWHAZ
Mean 552
Standard deviation 94
Values 6.2e+02 4.9e+02
[27]
THLE YWHAZ
Mean 232
Standard deviation 39
Values 2e+02 2.6e+02
[28]
liver YWHAZ
Mean 73.1
Standard deviation 31
Values 81 60 1.1e+02 39
[29]
ref_hepatocyte UBA52
Mean 57.3
Standard deviation 43
Values 14 23 49 1.2e+02 81
[30]
HepG2 UBA52
Mean 203
Standard deviation 20
Values 2.2e+02 1.9e+02
[31]
HepG2.C3A UBA52
Mean 169
Standard deviation 3.3
Values 1.7e+02 1.7e+02
[32]
HuH.7 UBA52
Mean 334
Standard deviation 46
Values 3.4e+02 2.8e+02 3.7e+02
[33]
SNU475 UBA52
Mean 72.9
Standard deviation 11
Values 65 81
[34]
THLE UBA52
Mean 144
Standard deviation 15
Values 1.3e+02 1.5e+02
[35]
liver UBA52
Mean 51.7
Standard deviation 26
Values 79 32 68 28
[36]
ref_hepatocyte PTPN11
Mean 22.2
Standard deviation 20
Values 33 53 10 7.5 7.4
[37]
HepG2 PTPN11
Mean 66.7
Standard deviation 12
Values 58 76
[38]
HepG2.C3A PTPN11
Mean 80.2
Standard deviation 17
Values 68 92
[39]
HuH.7 PTPN11
Mean 74.5
Standard deviation 12
Values 86 77 61
[40]
SNU475 PTPN11
Mean 75.4
Standard deviation 0.72
Values 75 76
[41]
THLE PTPN11
Mean 131
Standard deviation 5.1
Values 1.3e+02 1.3e+02
[42]
liver PTPN11
Mean 75.4
Standard deviation 18
Values 60 99 62 80
[43]
ref_hepatocyte GRB2
Mean 20.7
Standard deviation 5.5
Values 27 26 20 14 17
[44]
HepG2 GRB2
Mean 104
Standard deviation 4.7
Values 1e+02 1.1e+02
[45]
HepG2.C3A GRB2
Mean 83.1
Standard deviation 0.44
Values 83 83
[46]
HuH.7 GRB2
Mean 86.7
Standard deviation 7.6
Values 89 78 93
[47]
SNU475 GRB2
Mean 55.7
Standard deviation 1.4
Values 55 57
[48]
THLE GRB2
Mean 58.8
Standard deviation 3.7
Values 56 61
[49]
liver GRB2
Mean 36.1
Standard deviation 16
Values 50 22 50 22
[50]
ref_hepatocyte YES1
Mean 20.5
Standard deviation 18
Values 40 40 7.9 6.7 7.6
[51]
HepG2 YES1
Mean 24.9
Standard deviation 6
Values 21 29
[52]
HepG2.C3A YES1
Mean 62.3
Standard deviation 7.4
Values 57 68
[53]
HuH.7 YES1
Mean 69.8
Standard deviation 10
Values 74 77 58
[54]
SNU475 YES1
Mean 51.4
Standard deviation 2.5
Values 53 50
[55]
THLE YES1
Mean 39.7
Standard deviation 2
Values 41 38
[56]
liver YES1
Mean 31.7
Standard deviation 8
Values 27 39 23 38
[57]
ref_hepatocyte CRK
Mean 18.5
Standard deviation 12
Values 16 38 19 11 8.5
[58]
HepG2 CRK
Mean 35.5
Standard deviation 2.8
Values 34 38
[59]
HepG2.C3A CRK
Mean 30.2
Standard deviation 5.3
Values 27 34
[60]
HuH.7 CRK
Mean 30.3
Standard deviation 2.4
Values 32 32 28
[61]
SNU475 CRK
Mean 28.8
Standard deviation 1.2
Values 30 28
[62]
THLE CRK
Mean 42.5
Standard deviation 6.6
Values 38 47
[63]
liver CRK
Mean 47.1
Standard deviation 5.8
Values 41 55 45 47
[64]
ref_hepatocyte SHC1
Mean 16.6
Standard deviation 7.2
Values 5.8 17 19 26 16
[65]
HepG2 SHC1
Mean 82
Standard deviation 0.099
Values 82 82
[66]
HepG2.C3A SHC1
Mean 84.9
Standard deviation 11
Values 77 93
[67]
HuH.7 SHC1
Mean 85.9
Standard deviation 2.4
Values 89 84 85
[68]
SNU475 SHC1
Mean 191
Standard deviation 36
Values 2.2e+02 1.7e+02
[69]
THLE SHC1
Mean 150
Standard deviation 11
Values 1.4e+02 1.6e+02
[70]
liver SHC1
Mean 40.4
Standard deviation 11
Values 37 32 56 37
[71]
ref_hepatocyte PRKACA
Mean 15.8
Standard deviation 8.3
Values 7.6 11 11 27 23
[72]
HepG2 PRKACA
Mean 31.2
Standard deviation 2.7
Values 29 33
[73]
HepG2.C3A PRKACA
Mean 24.6
Standard deviation 3.5
Values 27 22
[74]
HuH.7 PRKACA
Mean 23.6
Standard deviation 5.7
Values 27 17 27
[75]
SNU475 PRKACA
Mean 21
Standard deviation 3.3
Values 23 19
[76]
THLE PRKACA
Mean 35.4
Standard deviation 5.3
Values 32 39
[77]
liver PRKACA
Mean 13.1
Standard deviation 4.9
Values 18 8.8 16 8.9
[78]
ref_hepatocyte JAK1
Mean 15.2
Standard deviation 7.8
Values 6.8 27 18 14 10
[79]
HepG2 JAK1
Mean 47.8
Standard deviation 11
Values 40 56
[80]
HepG2.C3A JAK1
Mean 29.8
Standard deviation 1.3
Values 31 29
[81]
HuH.7 JAK1
Mean 32.5
Standard deviation 3.3
Values 36 32 29
[82]
SNU475 JAK1
Mean 43.1
Standard deviation 5.5
Values 47 39
[83]
THLE JAK1
Mean 75.4
Standard deviation 6.9
Values 70 80
[84]
liver JAK1
Mean 62.3
Standard deviation 9.1
Values 54 75 58 62
[85]
ref_hepatocyte CRKL
Mean 7.86
Standard deviation 3.2
Values 13 7.5 7.1 6.1 5.2
[86]
HepG2 CRKL
Mean 56.6
Standard deviation 7.1
Values 52 62
[87]
HepG2.C3A CRKL
Mean 53.9
Standard deviation 8
Values 60 48
[88]
HuH.7 CRKL
Mean 78.7
Standard deviation 6.8
Values 86 76 74
[89]
SNU475 CRKL
Mean 31.5
Standard deviation 0.52
Values 32 31
[90]
THLE CRKL
Mean 40.6
Standard deviation 0.46
Values 41 40
[91]
liver CRKL
Mean 30.6
Standard deviation 3.9
Values 25 32 32 33
[92]
ref_hepatocyte PIK3R1
Mean 7.45
Standard deviation 3.9
Values 4.1 7.4 4.2 8.1 14
[93]
HepG2 PIK3R1
Mean 11.9
Standard deviation 3
Values 9.8 14
[94]
HepG2.C3A PIK3R1
Mean 11.5
Standard deviation 2.6
Values 9.6 13
[95]
HuH.7 PIK3R1
Mean 23.4
Standard deviation 8.6
Values 23 32 15
[96]
SNU475 PIK3R1
Mean 57.3
Standard deviation 32
Values 80 35
[97]
THLE PIK3R1
Mean 45.5
Standard deviation 1.5
Values 44 47
[98]
liver PIK3R1
Mean 84.8
Standard deviation 47
Values 64 1e+02 32 1.4e+02
[99]
ref_hepatocyte SOS1
Mean 6.81
Standard deviation 11
Values 27 1.9 2.2 1.3 1.5
[100]
HepG2 SOS1
Mean 14
Standard deviation 6.5
Values 9.4 19
[101]
HepG2.C3A SOS1
Mean 36.1
Standard deviation 3.7
Values 39 33
[102]
HuH.7 SOS1
Mean 24.6
Standard deviation 11
Values 22 37 15
[103]
SNU475 SOS1
Mean 22.5
Standard deviation 3.3
Values 25 20
[104]
THLE SOS1
Mean 14.8
Standard deviation 1.4
Values 16 14
[105]
liver SOS1
Mean 14.1
Standard deviation 3.8
Values 13 18 9.3 16
[106]
ref_hepatocyte BLNK
Mean 6.78
Standard deviation 7.3
Values 0 1.1 3.4 14 15
[107]
HepG2 BLNK
Mean 0.0193
Standard deviation 0.003
Values 0.017 0.021
[108]
HepG2.C3A BLNK
Mean 0.0156
Standard deviation 0.0083
Values 0.0097 0.021
[109]
HuH.7 BLNK
Mean 0.0755
Standard deviation 0.044
Values 0.11 0.083 0.028
[110]
SNU475 BLNK
Mean 0.00992
Standard deviation 0.0075
Values 0.0046 0.015
[111]
THLE BLNK
Mean 0.0302
Standard deviation 0.018
Values 0.018 0.043
[112]
liver BLNK
Mean 9.11
Standard deviation 8.1
Values 20 2.2 9.8 4.1
[113]
ref_hepatocyte LYN
Mean 5.33
Standard deviation 4.4
Values 0.29 6.8 12 3.7 3.8
[114]
HepG2 LYN
Mean 6.48
Standard deviation 1
Values 5.8 7.2
[115]
HepG2.C3A LYN
Mean 5.11
Standard deviation 2.1
Values 3.6 6.6
[116]
HuH.7 LYN
Mean 7.08
Standard deviation 0.67
Values 7.4 7.5 6.3
[117]
SNU475 LYN
Mean 20.4
Standard deviation 4.4
Values 17 23
[118]
THLE LYN
Mean 9.65
Standard deviation 1.4
Values 8.7 11
[119]
liver LYN
Mean 7.66
Standard deviation 1.7
Values 7.2 9.4 5.5 8.6
[120]
ref_hepatocyte PTPN6
Mean 5.33
Standard deviation 3
Values 2.2 3.1 4.4 7.6 9.3
[121]
HepG2 PTPN6
Mean 8.54
Standard deviation 0.054
Values 8.5 8.6
[122]
HepG2.C3A PTPN6
Mean 8.69
Standard deviation 0.18
Values 8.6 8.8
[123]
HuH.7 PTPN6
Mean 12.4
Standard deviation 1.9
Values 13 10 14
[124]
SNU475 PTPN6
Mean 0.0694
Standard deviation 0.026
Values 0.088 0.051
[125]
THLE PTPN6
Mean 2.52
Standard deviation 0.67
Values 2 3
[126]
liver PTPN6
Mean 6.69
Standard deviation 2
Values 7.5 4.8 9.1 5.4
[127]
ref_hepatocyte PIK3R2
Mean 5.25
Standard deviation 3.4
Values 11 3.2 3.1 4.9 3.8
[128]
HepG2 PIK3R2
Mean 42.5
Standard deviation 2.8
Values 44 41
[129]
HepG2.C3A PIK3R2
Mean 44.2
Standard deviation 13
Values 53 35
[130]
HuH.7 PIK3R2
Mean 64.7
Standard deviation 10
Values 75 55 64
[131]
SNU475 PIK3R2
Mean 15.7
Standard deviation 3.3
Values 18 13
[132]
THLE PIK3R2
Mean 26
Standard deviation 2.8
Values 24 28
[133]
liver PIK3R2
Mean 6.1
Standard deviation 1.7
Values 7.6 6 3.8 6.9
[134]
ref_hepatocyte RAPGEF1
Mean 4.9
Standard deviation 2.3
Values 6.6 5.4 7.5 2.5 2.6
[135]
HepG2 RAPGEF1
Mean 46
Standard deviation 2.9
Values 48 44
[136]
HepG2.C3A RAPGEF1
Mean 36.5
Standard deviation 6.8
Values 41 32
[137]
HuH.7 RAPGEF1
Mean 28.7
Standard deviation 4.9
Values 30 33 23
[138]
SNU475 RAPGEF1
Mean 21.5
Standard deviation 2.8
Values 23 20
[139]
THLE RAPGEF1
Mean 19.2
Standard deviation 5.1
Values 16 23
[140]
liver RAPGEF1
Mean 15.7
Standard deviation 4.8
Values 16 19 8.9 19
[141]
ref_hepatocyte STAT5B
Mean 3.99
Standard deviation 1.3
Values 4.1 3.3 2.3 4.6 5.6
[142]
HepG2 STAT5B
Mean 22.6
Standard deviation 6.3
Values 27 18
[143]
HepG2.C3A STAT5B
Mean 15.5
Standard deviation 4
Values 18 13
[144]
HuH.7 STAT5B
Mean 24.2
Standard deviation 2.2
Values 25 22 26
[145]
SNU475 STAT5B
Mean 21.5
Standard deviation 4
Values 24 19
[146]
THLE STAT5B
Mean 13.3
Standard deviation 0.2
Values 13 13
[147]
liver STAT5B
Mean 17.5
Standard deviation 4.7
Values 13 21 14 22
[148]
ref_hepatocyte INPPL1
Mean 3.88
Standard deviation 1.7
Values 2 2.9 6.2 5.2 3.2
[149]
HepG2 INPPL1
Mean 37.7
Standard deviation 3.4
Values 40 35
[150]
HepG2.C3A INPPL1
Mean 20.1
Standard deviation 6.4
Values 25 16
[151]
HuH.7 INPPL1
Mean 32.5
Standard deviation 0.66
Values 33 32 32
[152]
SNU475 INPPL1
Mean 71.4
Standard deviation 11
Values 79 63
[153]
THLE INPPL1
Mean 48.7
Standard deviation 0.9
Values 49 48
[154]
liver INPPL1
Mean 10.7
Standard deviation 5.3
Values 9.6 12 4.4 17
[155]
ref_hepatocyte PIK3CB
Mean 3.18
Standard deviation 1.5
Values 5.2 4.2 2.6 1.8 2.1
[156]
HepG2 PIK3CB
Mean 16.3
Standard deviation 2.1
Values 15 18
[157]
HepG2.C3A PIK3CB
Mean 20.6
Standard deviation 2.7
Values 23 19
[158]
HuH.7 PIK3CB
Mean 22.1
Standard deviation 2.1
Values 24 23 20
[159]
SNU475 PIK3CB
Mean 12.1
Standard deviation 2.7
Values 14 10
[160]
THLE PIK3CB
Mean 15.1
Standard deviation 0.94
Values 14 16
[161]
liver PIK3CB
Mean 10.1
Standard deviation 3.7
Values 6.4 15 7.9 11
[162]
ref_hepatocyte STAT5A
Mean 2.36
Standard deviation 1.6
Values 1.8 2.7 5 1.5 0.95
[163]
HepG2 STAT5A
Mean 1.35
Standard deviation 0.098
Values 1.4 1.3
[164]
HepG2.C3A STAT5A
Mean 2.72
Standard deviation 0.23
Values 2.6 2.9
[165]
HuH.7 STAT5A
Mean 1.37
Standard deviation 0.38
Values 1.1 1.8 1.2
[166]
SNU475 STAT5A
Mean 2.42
Standard deviation 0.13
Values 2.5 2.3
[167]
THLE STAT5A
Mean 4.58
Standard deviation 0.3
Values 4.8 4.4
[168]
liver STAT5A
Mean 3.96
Standard deviation 1.5
Values 3 3.5 3.3 6.2
[169]
ref_hepatocyte FYN
Mean 2.1
Standard deviation 2.2
Values 2.2 0.039 0.23 2.6 5.5
[170]
HepG2 FYN
Mean 8.91
Standard deviation 0.7
Values 9.4 8.4
[171]
HepG2.C3A FYN
Mean 0.0204
Standard deviation 0.0014
Values 0.019 0.021
[172]
HuH.7 FYN
Mean 7.43
Standard deviation 2.2
Values 8.9 4.8 8.5
[173]
SNU475 FYN
Mean 10.7
Standard deviation 2.5
Values 12 8.9
[174]
THLE FYN
Mean 34.5
Standard deviation 4.9
Values 38 31
[175]
liver FYN
Mean 5.84
Standard deviation 2.1
Values 8.9 4.4 5.1 5
[176]
ref_hepatocyte PIK3CA
Mean 1.87
Standard deviation 0.73
Values 2.3 2.6 2.3 1.2 0.94
[177]
HepG2 PIK3CA
Mean 3.17
Standard deviation 1.6
Values 2.1 4.3
[178]
HepG2.C3A PIK3CA
Mean 8.78
Standard deviation 1.1
Values 8 9.6
[179]
HuH.7 PIK3CA
Mean 9.59
Standard deviation 2.4
Values 10 12 7
[180]
SNU475 PIK3CA
Mean 7.49
Standard deviation 0.93
Values 8.1 6.8
[181]
THLE PIK3CA
Mean 9.67
Standard deviation 0.66
Values 10 9.2
[182]
liver PIK3CA
Mean 9.99
Standard deviation 4.7
Values 6.1 15 6 13
[183]
ref_hepatocyte PIK3CD
Mean 1.86
Standard deviation 1.7
Values 4.1 0.94 3.3 0.38 0.66
[184]
HepG2 PIK3CD
Mean 15.2
Standard deviation 3.8
Values 18 13
[185]
HepG2.C3A PIK3CD
Mean 28.8
Standard deviation 2.6
Values 31 27
[186]
HuH.7 PIK3CD
Mean 1.97
Standard deviation 0.32
Values 2 2.3 1.6
[187]
SNU475 PIK3CD
Mean 4.15
Standard deviation 0.57
Values 4.6 3.7
[188]
THLE PIK3CD
Mean 7.91
Standard deviation 1.1
Values 7.1 8.7
[189]
liver PIK3CD
Mean 3.25
Standard deviation 1.3
Values 2.4 3 2.6 5.1
[190]
ref_hepatocyte GAB2
Mean 1.62
Standard deviation 1.7
Values 1.2 1.9 4.5 0.25 0.31
[191]
HepG2 GAB2
Mean 10.6
Standard deviation 4.9
Values 14 7.1
[192]
HepG2.C3A GAB2
Mean 8.12
Standard deviation 3.2
Values 10 5.9
[193]
HuH.7 GAB2
Mean 9.24
Standard deviation 2.5
Values 9.6 12 6.6
[194]
SNU475 GAB2
Mean 5.63
Standard deviation 0.73
Values 6.1 5.1
[195]
THLE GAB2
Mean 6.7
Standard deviation 0.57
Values 7.1 6.3
[196]
liver GAB2
Mean 3.35
Standard deviation 1.3
Values 2.8 4.2 1.8 4.6
[197]
ref_hepatocyte HCK
Mean 1.57
Standard deviation 1.7
Values 0 0 2.7 1.2 3.9
[198]
HepG2 HCK
Mean 0.0602
Standard deviation 0.085
Values 0.12 0
[199]
HepG2.C3A HCK
Mean 0.0473
Standard deviation 0.039
Values 0.019 0.075
[200]
HuH.7 HCK
Mean 0
Standard deviation 0
Values 0 0 0
[201]
SNU475 HCK
Mean 0.0747
Standard deviation 0.066
Values 0.028 0.12
[202]
THLE HCK
Mean 0.0438
Standard deviation 0.047
Values 0.077 0.011
[203]
liver HCK
Mean 3.63
Standard deviation 1.3
Values 1.7 4.2 4 4.7
[204]
ref_hepatocyte INPP5D
Mean 1.08
Standard deviation 1.6
Values 3.8 0.096 0.065 0.29 1.1
[205]
HepG2 INPP5D
Mean 34.6
Standard deviation 2.7
Values 36 33
[206]
HepG2.C3A INPP5D
Mean 40.3
Standard deviation 7.8
Values 46 35
[207]
HuH.7 INPP5D
Mean 0.0331
Standard deviation 0.0052
Values 0.033 0.039 0.028
[208]
SNU475 INPP5D
Mean 0.0393
Standard deviation 0.016
Values 0.028 0.051
[209]
THLE INPP5D
Mean 0.34
Standard deviation 0.1
Values 0.41 0.27
[210]
liver INPP5D
Mean 3.74
Standard deviation 0.43
Values 3.6 3.5 3.5 4.4
[211]
ref_hepatocyte IL2RG
Mean 1.04
Standard deviation 1.2
Values 0 0 0.89 1.3 3
[212]
HepG2 IL2RG
Mean 0.733
Standard deviation 0.88
Values 1.4 0.11
[213]
HepG2.C3A IL2RG
Mean 0.176
Standard deviation 0.067
Values 0.22 0.13
[214]
HuH.7 IL2RG
Mean 0.264
Standard deviation 0.039
Values 0.25 0.24 0.31
[215]
SNU475 IL2RG
Mean 0.158
Standard deviation 0.092
Values 0.093 0.22
[216]
THLE IL2RG
Mean 0
Standard deviation 0
Values 0 0
[217]
liver IL2RG
Mean 1.37
Standard deviation 1.1
Values 2.4 0.51 2.2 0.41
[218]
ref_hepatocyte JAK2
Mean 0.762
Standard deviation 0.48
Values 1.3 1.3 0.62 0.18 0.5
[219]
HepG2 JAK2
Mean 1.97
Standard deviation 1.3
Values 1 2.9
[220]
HepG2.C3A JAK2
Mean 1.75
Standard deviation 0.67
Values 1.3 2.2
[221]
HuH.7 JAK2
Mean 1.23
Standard deviation 0.34
Values 1.2 1.6 0.9
[222]
SNU475 JAK2
Mean 2.37
Standard deviation 0.1
Values 2.3 2.4
[223]
THLE JAK2
Mean 4.02
Standard deviation 0.77
Values 4.6 3.5
[224]
liver JAK2
Mean 7.06
Standard deviation 3.8
Values 4.7 11 2.9 9.8
[225]
ref_hepatocyte TEC
Mean 0.721
Standard deviation 0.42
Values 0 1.1 0.86 0.85 0.8
[226]
HepG2 TEC
Mean 0.358
Standard deviation 0.094
Values 0.42 0.29
[227]
HepG2.C3A TEC
Mean 0.242
Standard deviation 0.067
Values 0.19 0.29
[228]
HuH.7 TEC
Mean 0.35
Standard deviation 0.086
Values 0.34 0.44 0.27
[229]
SNU475 TEC
Mean 3.35
Standard deviation 0.15
Values 3.5 3.2
[230]
THLE TEC
Mean 1.26
Standard deviation 0.036
Values 1.2 1.3
[231]
liver TEC
Mean 3.09
Standard deviation 0.67
Values 2.6 4 2.6 3.2
[232]
ref_hepatocyte CBL
Mean 0.522
Standard deviation 0.26
Values 0.83 0.62 0.65 0.18 0.33
[233]
HepG2 CBL
Mean 25.2
Standard deviation 0.64
Values 26 25
[234]
HepG2.C3A CBL
Mean 10.8
Standard deviation 0.61
Values 11 10
[235]
HuH.7 CBL
Mean 12.1
Standard deviation 3
Values 15 11 9.5
[236]
SNU475 CBL
Mean 33.7
Standard deviation 5.1
Values 30 37
[237]
THLE CBL
Mean 26.4
Standard deviation 3.4
Values 24 29
[238]
liver CBL
Mean 10
Standard deviation 4.2
Values 5.8 14 7.1 14
[239]
ref_hepatocyte VAV1
Mean 0.469
Standard deviation 0.4
Values 0 0.2 0.63 0.48 1
[240]
HepG2 VAV1
Mean 0.00287
Standard deviation 0.0041
Values 0.0057 0
[241]
HepG2.C3A VAV1
Mean 0.0726
Standard deviation 0.034
Values 0.049 0.097
[242]
HuH.7 VAV1
Mean 0.0213
Standard deviation 0.0061
Values 0.016 0.019 0.028
[243]
SNU475 VAV1
Mean 0.0127
Standard deviation 0.018
Values 0 0.025
[244]
THLE VAV1
Mean 0.00592
Standard deviation 0.0084
Values 0.012 0
[245]
liver VAV1
Mean 1.51
Standard deviation 0.9
Values 0.75 1.8 0.82 2.6
[246]
ref_hepatocyte CSF2RA
Mean 0.427
Standard deviation 0.37
Values 0.85 0.17 0.03 0.3 0.79
[247]
HepG2 CSF2RA
Mean 0
Standard deviation 0
Values 0 0
[248]
HepG2.C3A CSF2RA
Mean 0
Standard deviation 0
Values 0 0
[249]
HuH.7 CSF2RA
Mean 0
Standard deviation 0
Values 0 0 0
[250]
SNU475 CSF2RA
Mean 0
Standard deviation 0
Values 0 0
[251]
THLE CSF2RA
Mean 0
Standard deviation 0
Values 0 0
[252]
liver CSF2RA
Mean 0.00688
Standard deviation 0.008
Values 0 0.014 0 0.013
[253]
ref_hepatocyte IL2RB
Mean 0.407
Standard deviation 0.62
Values 0 0 0.23 0.31 1.5
[254]
HepG2 IL2RB
Mean 0.0329
Standard deviation 0.034
Values 0.057 0.0086
[255]
HepG2.C3A IL2RB
Mean 0.0199
Standard deviation 0.013
Values 0.029 0.011
[256]
HuH.7 IL2RB
Mean 0.00975
Standard deviation 0.0086
Values 0.016 0.013 0
[257]
SNU475 IL2RB
Mean 0.106
Standard deviation 0.065
Values 0.06 0.15
[258]
THLE IL2RB
Mean 0.0222
Standard deviation 0.0063
Values 0.018 0.027
[259]
liver IL2RB
Mean 1.68
Standard deviation 1.1
Values 1.7 0.61 3.3 1.1
[260]
ref_hepatocyte PIK3R3
Mean 0.405
Standard deviation 0.3
Values 0.52 0.81 0.47 0.078 0.15
[261]
HepG2 PIK3R3
Mean 2.95
Standard deviation 2.5
Values 1.2 4.7
[262]
HepG2.C3A PIK3R3
Mean 2.65
Standard deviation 1.6
Values 1.5 3.8
[263]
HuH.7 PIK3R3
Mean 4.56
Standard deviation 1.3
Values 5.7 3.1 5
[264]
SNU475 PIK3R3
Mean 6.68
Standard deviation 0.22
Values 6.5 6.8
[265]
THLE PIK3R3
Mean 3.8
Standard deviation 0.9
Values 3.2 4.4
[266]
liver PIK3R3
Mean 3.68
Standard deviation 0.27
Values 3.7 3.8 3.3 4
[267]
ref_hepatocyte SYK
Mean 0.279
Standard deviation 0.38
Values 0 0.17 0 0.31 0.92
[268]
HepG2 SYK
Mean 0.00214
Standard deviation 0.003
Values 0 0.0043
[269]
HepG2.C3A SYK
Mean 0.112
Standard deviation 0.0066
Values 0.12 0.11
[270]
HuH.7 SYK
Mean 0.0133
Standard deviation 0.0053
Values 0.0082 0.013 0.019
[271]
SNU475 SYK
Mean 0.549
Standard deviation 0.36
Values 0.3 0.8
[272]
THLE SYK
Mean 0.0538
Standard deviation 0.016
Values 0.065 0.043
[273]
liver SYK
Mean 4.07
Standard deviation 1.3
Values 3.6 4.8 2.5 5.4
[274]
ref_hepatocyte IL3RA
Mean 0.248
Standard deviation 0.27
Values 0 0 0.64 0.22 0.37
[275]
HepG2 IL3RA
Missing
[276]
HepG2.C3A IL3RA
Missing
[277]
HuH.7 IL3RA
Missing
[278]
SNU475 IL3RA
Missing
[279]
THLE IL3RA
Missing
[280]
liver IL3RA
Missing
[281]
ref_hepatocyte JAK3
Mean 0.235
Standard deviation 0.23
Values 0.61 0.026 0.15 0.078 0.31
[282]
HepG2 JAK3
Mean 2.46
Standard deviation 0.35
Values 2.7 2.2
[283]
HepG2.C3A JAK3
Mean 10.6
Standard deviation 4.3
Values 14 7.6
[284]
HuH.7 JAK3
Mean 0.158
Standard deviation 0.069
Values 0.11 0.24 0.12
[285]
SNU475 JAK3
Mean 0.279
Standard deviation 0.0072
Values 0.27 0.28
[286]
THLE JAK3
Mean 0.519
Standard deviation 0.094
Values 0.59 0.45
[287]
liver JAK3
Mean 2.86
Standard deviation 0.73
Values 2.8 2.2 2.5 3.9
[288]
ref_hepatocyte CSF2RB
Mean 0.195
Standard deviation 0.18
Values 0 0.023 0.33 0.21 0.41
[289]
HepG2 CSF2RB
Mean 0
Standard deviation 0
Values 0 0
[290]
HepG2.C3A CSF2RB
Mean 0
Standard deviation 0
Values 0 0
[291]
HuH.7 CSF2RB
Mean 0
Standard deviation 0
Values 0 0 0
[292]
SNU475 CSF2RB
Mean 0.00507
Standard deviation 0.0072
Values 0 0.01
[293]
THLE CSF2RB
Mean 0.0281
Standard deviation 0.0021
Values 0.03 0.027
[294]
liver CSF2RB
Mean 2.02
Standard deviation 0.86
Values 1.1 2.7 1.5 2.8
[295]
ref_hepatocyte IL2RA
Mean 0.131
Standard deviation 0.1
Values 0.15 0.26 0.19 0 0.057
[296]
HepG2 IL2RA
Mean 0
Standard deviation 0
Values 0 0
[297]
HepG2.C3A IL2RA
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[298]
HuH.7 IL2RA
Mean 0
Standard deviation 0
Values 0 0 0
[299]
SNU475 IL2RA
Mean 0.00992
Standard deviation 0.0075
Values 0.0046 0.015
[300]
THLE IL2RA
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[301]
liver IL2RA
Mean 0.27
Standard deviation 0.33
Values 0.024 0.2 0.1 0.75
[302]
ref_hepatocyte CSF2
Mean 0.0306
Standard deviation 0.068
Values 0 0.15 0 0 0
[303]
HepG2 CSF2
Mean 0.0931
Standard deviation 0.095
Values 0.16 0.026
[304]
HepG2.C3A CSF2
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[305]
HuH.7 CSF2
Mean 0.008
Standard deviation 0.0015
Values 0.0082 0.0064 0.0094
[306]
SNU475 CSF2
Mean 0.0171
Standard deviation 0.0045
Values 0.014 0.02
[307]
THLE CSF2
Mean 4.56
Standard deviation 2.6
Values 2.7 6.4
[308]
liver CSF2
Mean 0.0156
Standard deviation 0.012
Values 0.024 0 0.026 0.013
[309]
ref_hepatocyte IL5RA
Mean 0.00813
Standard deviation 0.018
Values 0 0 0 0 0.041
[310]
HepG2 IL5RA
Mean 0
Standard deviation 0
Values 0 0
[311]
HepG2.C3A IL5RA
Mean 0
Standard deviation 0
Values 0 0
[312]
HuH.7 IL5RA
Mean 0
Standard deviation 0
Values 0 0 0
[313]
SNU475 IL5RA
Mean 0.00992
Standard deviation 0.0075
Values 0.0046 0.015
[314]
THLE IL5RA
Mean 0.0118
Standard deviation 0.017
Values 0.024 0
[315]
liver IL5RA
Mean 0.0581
Standard deviation 0.068
Values 0 0.1 0 0.13
[316]
ref_hepatocyte IL2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[317]
HepG2 IL2
Mean 0
Standard deviation 0
Values 0 0
[318]
HepG2.C3A IL2
Mean 0
Standard deviation 0
Values 0 0
[319]
HuH.7 IL2
Mean 0
Standard deviation 0
Values 0 0 0
[320]
SNU475 IL2
Mean 0.00464
Standard deviation 0.0066
Values 0.0093 0
[321]
THLE IL2
Mean 0
Standard deviation 0
Values 0 0
[322]
liver IL2
Mean 0.00918
Standard deviation 0.011
Values 0.024 0 0 0.013
[323]
ref_hepatocyte IL3
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[324]
HepG2 IL3
Mean 0
Standard deviation 0
Values 0 0
[325]
HepG2.C3A IL3
Mean 0
Standard deviation 0
Values 0 0
[326]
HuH.7 IL3
Mean 0
Standard deviation 0
Values 0 0 0
[327]
SNU475 IL3
Mean 0
Standard deviation 0
Values 0 0
[328]
THLE IL3
Mean 0
Standard deviation 0
Values 0 0
[329]
liver IL3
Mean 0.0372
Standard deviation 0.036
Values 0.024 0.086 0 0.04
[330]
ref_hepatocyte IL5
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[331]
HepG2 IL5
Mean 0.00287
Standard deviation 0.0041
Values 0.0057 0
[332]
HepG2.C3A IL5
Mean 0
Standard deviation 0
Values 0 0
[333]
HuH.7 IL5
Mean 0
Standard deviation 0
Values 0 0 0
[334]
SNU475 IL5
Mean 0
Standard deviation 0
Values 0 0
[335]
THLE IL5
Mean 0.0177
Standard deviation 0.025
Values 0.035 0
[336]
liver IL5
Mean 0.0132
Standard deviation 0.026
Values 0 0 0 0.053