REACTOME_INTERLEUKIN_35_SIGNALLING Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 CANX Calnexin [1] -0.07[2] 0.18[3] 0.23[4] -0.39[5] -0.38[6] -0.54[7]
2 STAT3 Signal transducer and activator of transcription 3 [8] 0.24[9] -1.48[10] -1.01[11] -0.77[12] -1.39[13] 0.48[14]
3 STAT1 Signal transducer and activator of transcription 1-alpha/beta [15] -0.38[16] -1.52[17] -0.68[18] 1.51[19] -0.64[20] -0.98[21]
4 IL6ST Interleukin-6 receptor subunit beta [22] -0.05[23] 0.98[24] 0.23[25] 0.71[26] 1.99[27] 1.85[28]
5 JAK1 Tyrosine-protein kinase JAK1 [29] 0.20[30] -0.53[31] -0.62[32] -0.39[33] 0.37[34] -0.40[35]
6 TYK2 Non-receptor tyrosine-protein kinase TYK2 [36] 0.83[37] 0.97[38] 0.83[39] -0.27[40] 0.77[41] 0.06[42]
7 EBI3 Interleukin-27 subunit beta [43] -1.14[44] -0.65[45] -3.74[46] -1.33[47] -5.29[48] -2.98[49]
8 STAT4 Signal transducer and activator of transcription 4 [50] -5.15[51] -4.30[52] -4.04[53] 0.62[54] -0.46[55] -0.90[56]
9 JAK2 Tyrosine-protein kinase JAK2 [57] -0.08[58] -0.31[59] -1.02[60] -0.25[61] 0.45[62] 0.77[63]
10 IL27RA Interleukin-27 receptor subunit alpha [64] 1.55[65] 1.76[66] 1.77[67] -1.34[68] 0.28[69] -1.49[70]
11 IL12A Interleukin-12 subunit alpha [71] -1.72[72] [73] -0.71[74] -2.56[75] -0.65[76] -5.11[77]
12 IL12RB2 Interleukin-12 receptor subunit beta-2 [78] 2.56[79] 2.94[80] 4.70[81] 4.38[82] 2.56[83] 6.03[84]
[1]
ref_hepatocyte CANX
Mean 128
Standard deviation 89
Values 2.7e+02 1.4e+02 43 1.1e+02 75
[2]
HepG2 CANX
Mean 335
Standard deviation 37
Values 3.1e+02 3.6e+02
[3]
HepG2.C3A CANX
Mean 411
Standard deviation 40
Values 4.4e+02 3.8e+02
[4]
HuH.7 CANX
Mean 494
Standard deviation 1.9e+02
Values 4.4e+02 7.1e+02 3.4e+02
[5]
SNU475 CANX
Mean 362
Standard deviation 31
Values 3.8e+02 3.4e+02
[6]
THLE CANX
Mean 379
Standard deviation 58
Values 3.4e+02 4.2e+02
[7]
liver CANX
Mean 477
Standard deviation 1.8e+02
Values 2.6e+02 6.9e+02 4.4e+02 5.2e+02
[8]
ref_hepatocyte STAT3
Mean 30.1
Standard deviation 11
Values 26 25 18 46 36
[9]
HepG2 STAT3
Mean 97.5
Standard deviation 10
Values 90 1e+02
[10]
HepG2.C3A STAT3
Mean 30.7
Standard deviation 5.2
Values 34 27
[11]
HuH.7 STAT3
Mean 49.1
Standard deviation 15
Values 47 65 35
[12]
SNU475 STAT3
Mean 65.4
Standard deviation 12
Values 74 57
[13]
THLE STAT3
Mean 44.3
Standard deviation 6
Values 40 49
[14]
liver STAT3
Mean 227
Standard deviation 42
Values 1.9e+02 2.3e+02 2.8e+02 2e+02
[15]
ref_hepatocyte STAT1
Mean 20.3
Standard deviation 8.7
Values 17 35 19 12 18
[16]
HepG2 STAT1
Mean 42.7
Standard deviation 9.4
Values 36 49
[17]
HepG2.C3A STAT1
Mean 20.1
Standard deviation 7.2
Values 15 25
[18]
HuH.7 STAT1
Mean 41.6
Standard deviation 4.5
Values 47 38 40
[19]
SNU475 STAT1
Mean 216
Standard deviation 1.4e+02
Values 3.2e+02 1.1e+02
[20]
THLE STAT1
Mean 50.3
Standard deviation 2.1
Values 49 52
[21]
liver STAT1
Mean 55.8
Standard deviation 15
Values 49 69 67 38
[22]
ref_hepatocyte IL6ST
Mean 16.5
Standard deviation 5.8
Values 24 18 9.5 12 19
[23]
HepG2 IL6ST
Mean 43.6
Standard deviation 25
Values 26 61
[24]
HepG2.C3A IL6ST
Mean 92.3
Standard deviation 8.3
Values 86 98
[25]
HuH.7 IL6ST
Mean 63.5
Standard deviation 38
Values 50 1.1e+02 35
[26]
SNU475 IL6ST
Mean 100
Standard deviation 15
Values 90 1.1e+02
[27]
THLE IL6ST
Mean 252
Standard deviation 68
Values 3e+02 2e+02
[28]
liver IL6ST
Mean 321
Standard deviation 1.1e+02
Values 2.5e+02 4.2e+02 2.1e+02 4.1e+02
[29]
ref_hepatocyte JAK1
Mean 15.2
Standard deviation 7.8
Values 6.8 27 18 14 10
[30]
HepG2 JAK1
Mean 47.8
Standard deviation 11
Values 40 56
[31]
HepG2.C3A JAK1
Mean 29.8
Standard deviation 1.3
Values 31 29
[32]
HuH.7 JAK1
Mean 32.5
Standard deviation 3.3
Values 36 32 29
[33]
SNU475 JAK1
Mean 43.1
Standard deviation 5.5
Values 47 39
[34]
THLE JAK1
Mean 75.4
Standard deviation 6.9
Values 70 80
[35]
liver JAK1
Mean 62.3
Standard deviation 9.1
Values 54 75 58 62
[36]
ref_hepatocyte TYK2
Mean 4.82
Standard deviation 1.6
Values 2.6 4 5.2 6.8 5.6
[37]
HepG2 TYK2
Mean 23.5
Standard deviation 0.9
Values 23 24
[38]
HepG2.C3A TYK2
Mean 26.8
Standard deviation 2.6
Values 29 25
[39]
HuH.7 TYK2
Mean 28.1
Standard deviation 8.5
Values 35 19 31
[40]
SNU475 TYK2
Mean 14.9
Standard deviation 0.21
Values 15 15
[41]
THLE TYK2
Mean 31.6
Standard deviation 1.6
Values 33 31
[42]
liver TYK2
Mean 27.2
Standard deviation 3.5
Values 31 24 24 30
[43]
ref_hepatocyte EBI3
Mean 1.37
Standard deviation 1.7
Values 0 0.73 4.3 1.1 0.64
[44]
HepG2 EBI3
Mean 1.69
Standard deviation 1.4
Values 2.7 0.72
[45]
HepG2.C3A EBI3
Mean 2.47
Standard deviation 1.4
Values 3.5 1.5
[46]
HuH.7 EBI3
Mean 0.335
Standard deviation 0.16
Values 0.27 0.52 0.22
[47]
SNU475 EBI3
Mean 2.01
Standard deviation 0.1
Values 1.9 2.1
[48]
THLE EBI3
Mean 0.134
Standard deviation 0.0058
Values 0.13 0.14
[49]
liver EBI3
Mean 0.939
Standard deviation 0.7
Values 1.3 0.23 1.7 0.49
[50]
ref_hepatocyte STAT4
Mean 0.825
Standard deviation 0.62
Values 0 1.4 0.35 1 1.3
[51]
HepG2 STAT4
Mean 0.0637
Standard deviation 0.025
Values 0.046 0.082
[52]
HepG2.C3A STAT4
Mean 0.119
Standard deviation 0.044
Values 0.087 0.15
[53]
HuH.7 STAT4
Mean 0.164
Standard deviation 0.023
Values 0.16 0.14 0.19
[54]
SNU475 STAT4
Mean 4.7
Standard deviation 1.3
Values 5.6 3.8
[55]
THLE STAT4
Mean 2.3
Standard deviation 1.2
Values 3.1 1.5
[56]
liver STAT4
Mean 2.39
Standard deviation 1.1
Values 3 1.5 1.4 3.7
[57]
ref_hepatocyte JAK2
Mean 0.762
Standard deviation 0.48
Values 1.3 1.3 0.62 0.18 0.5
[58]
HepG2 JAK2
Mean 1.97
Standard deviation 1.3
Values 1 2.9
[59]
HepG2.C3A JAK2
Mean 1.75
Standard deviation 0.67
Values 1.3 2.2
[60]
HuH.7 JAK2
Mean 1.23
Standard deviation 0.34
Values 1.2 1.6 0.9
[61]
SNU475 JAK2
Mean 2.37
Standard deviation 0.1
Values 2.3 2.4
[62]
THLE JAK2
Mean 4.02
Standard deviation 0.77
Values 4.6 3.5
[63]
liver JAK2
Mean 7.06
Standard deviation 3.8
Values 4.7 11 2.9 9.8
[64]
ref_hepatocyte IL27RA
Mean 0.619
Standard deviation 0.41
Values 0.43 1.3 0.27 0.52 0.54
[65]
HepG2 IL27RA
Mean 4.95
Standard deviation 0.37
Values 5.2 4.7
[66]
HepG2.C3A IL27RA
Mean 5.97
Standard deviation 0.58
Values 5.6 6.4
[67]
HuH.7 IL27RA
Mean 6.92
Standard deviation 0.27
Values 6.8 6.7 7.2
[68]
SNU475 IL27RA
Mean 0.905
Standard deviation 0.37
Values 0.64 1.2
[69]
THLE IL27RA
Mean 2.89
Standard deviation 0.15
Values 2.8 3
[70]
liver IL27RA
Mean 1.19
Standard deviation 0.32
Values 1.6 0.83 1.1 1.3
[71]
ref_hepatocyte IL12A
Mean 0.149
Standard deviation 0.3
Values 0 0 0.69 0 0.057
[72]
HepG2 IL12A
Mean 0.125
Standard deviation 0.091
Values 0.19 0.06
[73]
HepG2.C3A IL12A
Mean 0
Standard deviation 0
Values 0 0
[74]
HuH.7 IL12A
Mean 0.299
Standard deviation 0.11
Values 0.29 0.2 0.41
[75]
SNU475 IL12A
Mean 0.0941
Standard deviation 0.011
Values 0.1 0.086
[76]
THLE IL12A
Mean 0.367
Standard deviation 0.0081
Values 0.36 0.37
[77]
liver IL12A
Mean 0.0235
Standard deviation 0.047
Values 0.094 0 0 0
[78]
ref_hepatocyte IL12RB2
Mean 0.00311
Standard deviation 0.007
Values 0 0.016 0 0 0
[79]
HepG2 IL12RB2
Mean 0.0501
Standard deviation 0.034
Values 0.074 0.026
[80]
HepG2.C3A IL12RB2
Mean 0.0677
Standard deviation 0.041
Values 0.039 0.097
[81]
HuH.7 IL12RB2
Mean 0.265
Standard deviation 0.086
Values 0.34 0.29 0.17
[82]
SNU475 IL12RB2
Mean 0.241
Standard deviation 0.18
Values 0.11 0.37
[83]
THLE IL12RB2
Mean 0.0707
Standard deviation 0.017
Values 0.083 0.059
[84]
liver IL12RB2
Mean 1.1
Standard deviation 0.9
Values 0.66 1 0.36 2.4