REACTOME_INTERLEUKIN_2_SIGNALING Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 SHC1 SHC-transforming protein 1 [1] 0.35[2] 0.50[3] 0.51[4] 0.90[5] 0.61[6] -0.48[7]
2 JAK1 Tyrosine-protein kinase JAK1 [8] -0.30[9] -0.89[10] -0.77[11] -1.12[12] -0.25[13] 0.27[14]
3 STAT5B Signal transducer and activator of transcription 5B [15] 0.54[16] 0.10[17] 0.74[18] -0.20[19] -0.83[20] 0.36[21]
4 STAT5A Signal transducer and activator of transcription 5A [22] -2.76[23] -1.66[24] -2.65[25] -2.59[26] -1.61[27] -1.02[28]
5 PTK2B Protein-tyrosine kinase 2-beta [29] -1.62[30] -0.34[31] 0.57[32] -3.53[33] -0.68[34] 0.51[35]
6 IL2RG Cytokine receptor common subunit gamma [36] -2.46[37] -4.42[38] -3.84[39] -5.34[40] [41] -1.37[42]
7 IL2RB Interleukin-2 receptor subunit beta [43] -5.58[44] -6.21[45] -7.25[46] -4.56[47] -6.76[48] 0.28[49]
8 LCK Tyrosine-protein kinase Lck [50] 1.96[51] 1.97[52] -8.08[53] -6.83[54] -6.81[55] -0.03[56]
9 SYK Tyrosine-protein kinase SYK [57] -8.98[58] -3.18[59] -6.26[60] -1.65[61] -4.94[62] 2.10[63]
10 JAK3 Tyrosine-protein kinase JAK3 [64] 1.43[65] 3.63[66] -2.44[67] -2.38[68] -1.43[69] 1.84[70]
11 IL2RA Interleukin-2 receptor subunit alpha [71] [72] -6.48[73] [74] -6.35[75] -8.04[76] -0.73[77]
12 IL2 Interleukin-2 [78] [79] [80] [81] [82] [83] [84]
[1]
ref_hepatocyte SHC1
Mean 16.6
Standard deviation 7.2
Values 5.8 17 19 26 16
[2]
HepG2 SHC1
Mean 82
Standard deviation 0.099
Values 82 82
[3]
HepG2.C3A SHC1
Mean 84.9
Standard deviation 11
Values 77 93
[4]
HuH.7 SHC1
Mean 85.9
Standard deviation 2.4
Values 89 84 85
[5]
SNU475 SHC1
Mean 191
Standard deviation 36
Values 2.2e+02 1.7e+02
[6]
THLE SHC1
Mean 150
Standard deviation 11
Values 1.4e+02 1.6e+02
[7]
liver SHC1
Mean 40.4
Standard deviation 11
Values 37 32 56 37
[8]
ref_hepatocyte JAK1
Mean 15.2
Standard deviation 7.8
Values 6.8 27 18 14 10
[9]
HepG2 JAK1
Mean 47.8
Standard deviation 11
Values 40 56
[10]
HepG2.C3A JAK1
Mean 29.8
Standard deviation 1.3
Values 31 29
[11]
HuH.7 JAK1
Mean 32.5
Standard deviation 3.3
Values 36 32 29
[12]
SNU475 JAK1
Mean 43.1
Standard deviation 5.5
Values 47 39
[13]
THLE JAK1
Mean 75.4
Standard deviation 6.9
Values 70 80
[14]
liver JAK1
Mean 62.3
Standard deviation 9.1
Values 54 75 58 62
[15]
ref_hepatocyte STAT5B
Mean 3.99
Standard deviation 1.3
Values 4.1 3.3 2.3 4.6 5.6
[16]
HepG2 STAT5B
Mean 22.6
Standard deviation 6.3
Values 27 18
[17]
HepG2.C3A STAT5B
Mean 15.5
Standard deviation 4
Values 18 13
[18]
HuH.7 STAT5B
Mean 24.2
Standard deviation 2.2
Values 25 22 26
[19]
SNU475 STAT5B
Mean 21.5
Standard deviation 4
Values 24 19
[20]
THLE STAT5B
Mean 13.3
Standard deviation 0.2
Values 13 13
[21]
liver STAT5B
Mean 17.5
Standard deviation 4.7
Values 13 21 14 22
[22]
ref_hepatocyte STAT5A
Mean 2.36
Standard deviation 1.6
Values 1.8 2.7 5 1.5 0.95
[23]
HepG2 STAT5A
Mean 1.35
Standard deviation 0.098
Values 1.4 1.3
[24]
HepG2.C3A STAT5A
Mean 2.72
Standard deviation 0.23
Values 2.6 2.9
[25]
HuH.7 STAT5A
Mean 1.37
Standard deviation 0.38
Values 1.1 1.8 1.2
[26]
SNU475 STAT5A
Mean 2.42
Standard deviation 0.13
Values 2.5 2.3
[27]
THLE STAT5A
Mean 4.58
Standard deviation 0.3
Values 4.8 4.4
[28]
liver STAT5A
Mean 3.96
Standard deviation 1.5
Values 3 3.5 3.3 6.2
[29]
ref_hepatocyte PTK2B
Mean 1.68
Standard deviation 1.2
Values 0.39 0.56 2.1 2.2 3.2
[30]
HepG2 PTK2B
Mean 2.13
Standard deviation 0.072
Values 2.2 2.1
[31]
HepG2.C3A PTK2B
Mean 4.85
Standard deviation 0.49
Values 5.2 4.5
[32]
HuH.7 PTK2B
Mean 9.07
Standard deviation 0.34
Values 9.5 8.9 8.8
[33]
SNU475 PTK2B
Mean 0.901
Standard deviation 0.46
Values 1.2 0.57
[34]
THLE PTK2B
Mean 6.23
Standard deviation 0.98
Values 6.9 5.5
[35]
liver PTK2B
Mean 8.17
Standard deviation 0.99
Values 8.5 7.3 7.4 9.4
[36]
ref_hepatocyte IL2RG
Mean 1.04
Standard deviation 1.2
Values 0 0 0.89 1.3 3
[37]
HepG2 IL2RG
Mean 0.733
Standard deviation 0.88
Values 1.4 0.11
[38]
HepG2.C3A IL2RG
Mean 0.176
Standard deviation 0.067
Values 0.22 0.13
[39]
HuH.7 IL2RG
Mean 0.264
Standard deviation 0.039
Values 0.25 0.24 0.31
[40]
SNU475 IL2RG
Mean 0.158
Standard deviation 0.092
Values 0.093 0.22
[41]
THLE IL2RG
Mean 0
Standard deviation 0
Values 0 0
[42]
liver IL2RG
Mean 1.37
Standard deviation 1.1
Values 2.4 0.51 2.2 0.41
[43]
ref_hepatocyte IL2RB
Mean 0.407
Standard deviation 0.62
Values 0 0 0.23 0.31 1.5
[44]
HepG2 IL2RB
Mean 0.0329
Standard deviation 0.034
Values 0.057 0.0086
[45]
HepG2.C3A IL2RB
Mean 0.0199
Standard deviation 0.013
Values 0.029 0.011
[46]
HuH.7 IL2RB
Mean 0.00975
Standard deviation 0.0086
Values 0.016 0.013 0
[47]
SNU475 IL2RB
Mean 0.106
Standard deviation 0.065
Values 0.06 0.15
[48]
THLE IL2RB
Mean 0.0222
Standard deviation 0.0063
Values 0.018 0.027
[49]
liver IL2RB
Mean 1.68
Standard deviation 1.1
Values 1.7 0.61 3.3 1.1
[50]
ref_hepatocyte LCK
Mean 0.319
Standard deviation 0.43
Values 0.11 0 0.49 0 0.99
[51]
HepG2 LCK
Mean 4.84
Standard deviation 4.4
Values 8 1.7
[52]
HepG2.C3A LCK
Mean 4.55
Standard deviation 0.16
Values 4.4 4.7
[53]
HuH.7 LCK
Mean 0.00428
Standard deviation 0.0074
Values 0 0.013 0
[54]
SNU475 LCK
Mean 0.0173
Standard deviation 0.011
Values 0.0093 0.025
[55]
THLE LCK
Mean 0.0169
Standard deviation 0.0013
Values 0.018 0.016
[56]
liver LCK
Mean 1.07
Standard deviation 0.51
Values 1.2 0.49 1.7 0.91
[57]
ref_hepatocyte SYK
Mean 0.279
Standard deviation 0.38
Values 0 0.17 0 0.31 0.92
[58]
HepG2 SYK
Mean 0.00214
Standard deviation 0.003
Values 0 0.0043
[59]
HepG2.C3A SYK
Mean 0.112
Standard deviation 0.0066
Values 0.12 0.11
[60]
HuH.7 SYK
Mean 0.0133
Standard deviation 0.0053
Values 0.0082 0.013 0.019
[61]
SNU475 SYK
Mean 0.549
Standard deviation 0.36
Values 0.3 0.8
[62]
THLE SYK
Mean 0.0538
Standard deviation 0.016
Values 0.065 0.043
[63]
liver SYK
Mean 4.07
Standard deviation 1.3
Values 3.6 4.8 2.5 5.4
[64]
ref_hepatocyte JAK3
Mean 0.235
Standard deviation 0.23
Values 0.61 0.026 0.15 0.078 0.31
[65]
HepG2 JAK3
Mean 2.46
Standard deviation 0.35
Values 2.7 2.2
[66]
HepG2.C3A JAK3
Mean 10.6
Standard deviation 4.3
Values 14 7.6
[67]
HuH.7 JAK3
Mean 0.158
Standard deviation 0.069
Values 0.11 0.24 0.12
[68]
SNU475 JAK3
Mean 0.279
Standard deviation 0.0072
Values 0.27 0.28
[69]
THLE JAK3
Mean 0.519
Standard deviation 0.094
Values 0.59 0.45
[70]
liver JAK3
Mean 2.86
Standard deviation 0.73
Values 2.8 2.2 2.5 3.9
[71]
ref_hepatocyte IL2RA
Mean 0.131
Standard deviation 0.1
Values 0.15 0.26 0.19 0 0.057
[72]
HepG2 IL2RA
Mean 0
Standard deviation 0
Values 0 0
[73]
HepG2.C3A IL2RA
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[74]
HuH.7 IL2RA
Mean 0
Standard deviation 0
Values 0 0 0
[75]
SNU475 IL2RA
Mean 0.00992
Standard deviation 0.0075
Values 0.0046 0.015
[76]
THLE IL2RA
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[77]
liver IL2RA
Mean 0.27
Standard deviation 0.33
Values 0.024 0.2 0.1 0.75
[78]
ref_hepatocyte IL2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[79]
HepG2 IL2
Mean 0
Standard deviation 0
Values 0 0
[80]
HepG2.C3A IL2
Mean 0
Standard deviation 0
Values 0 0
[81]
HuH.7 IL2
Mean 0
Standard deviation 0
Values 0 0 0
[82]
SNU475 IL2
Mean 0.00464
Standard deviation 0.0066
Values 0.0093 0
[83]
THLE IL2
Mean 0
Standard deviation 0
Values 0 0
[84]
liver IL2
Mean 0.00918
Standard deviation 0.011
Values 0.024 0 0 0.013