REACTOME_INTERLEUKIN_27_SIGNALING Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 CANX Calnexin [1] -0.56[2] -0.09[3] 0.24[4] -0.37[5] -0.36[6] -0.52[7]
2 STAT3 Signal transducer and activator of transcription 3 [8] -0.26[9] -1.75[10] -1.00[11] -0.75[12] -1.37[13] 0.49[14]
3 STAT1 Signal transducer and activator of transcription 1-alpha/beta [15] -0.88[16] -1.79[17] -0.68[18] 1.54[19] -0.62[20] -0.96[21]
4 IL6ST Interleukin-6 receptor subunit beta [22] -0.55[23] 0.71[24] 0.24[25] 0.73[26] 2.01[27] 1.86[28]
5 JAK1 Tyrosine-protein kinase JAK1 [29] -0.30[30] -0.80[31] -0.61[32] -0.37[33] 0.38[34] -0.39[35]
6 TYK2 Non-receptor tyrosine-protein kinase TYK2 [36] 0.33[37] 0.70[38] 0.84[39] -0.25[40] 0.78[41] 0.07[42]
7 IL27 Interleukin-27 subunit alpha [43] -6.65[44] -5.00[45] -2.11[46] [47] -11.30[48] -3.61[49]
8 EBI3 Interleukin-27 subunit beta [50] -1.64[51] -0.92[52] -3.73[53] -1.31[54] -5.28[55] -2.96[56]
9 CRLF1 Cytokine receptor-like factor 1 [57] 5.96[58] 5.20[59] -1.22[60] -3.98[61] -3.82[62] -5.84[63]
10 JAK2 Tyrosine-protein kinase JAK2 [64] -0.58[65] -0.58[66] -1.01[67] -0.23[68] 0.47[69] 0.79[70]
11 IL27RA Interleukin-27 receptor subunit alpha [71] 1.05[72] 1.50[73] 1.78[74] -1.32[75] 0.29[76] -1.48[77]
[1]
ref_hepatocyte CANX
Mean 128
Standard deviation 89
Values 2.7e+02 1.4e+02 43 1.1e+02 75
[2]
HepG2 CANX
Mean 335
Standard deviation 37
Values 3.1e+02 3.6e+02
[3]
HepG2.C3A CANX
Mean 411
Standard deviation 40
Values 4.4e+02 3.8e+02
[4]
HuH.7 CANX
Mean 494
Standard deviation 1.9e+02
Values 4.4e+02 7.1e+02 3.4e+02
[5]
SNU475 CANX
Mean 362
Standard deviation 31
Values 3.8e+02 3.4e+02
[6]
THLE CANX
Mean 379
Standard deviation 58
Values 3.4e+02 4.2e+02
[7]
liver CANX
Mean 477
Standard deviation 1.8e+02
Values 2.6e+02 6.9e+02 4.4e+02 5.2e+02
[8]
ref_hepatocyte STAT3
Mean 30.1
Standard deviation 11
Values 26 25 18 46 36
[9]
HepG2 STAT3
Mean 97.5
Standard deviation 10
Values 90 1e+02
[10]
HepG2.C3A STAT3
Mean 30.7
Standard deviation 5.2
Values 34 27
[11]
HuH.7 STAT3
Mean 49.1
Standard deviation 15
Values 47 65 35
[12]
SNU475 STAT3
Mean 65.4
Standard deviation 12
Values 74 57
[13]
THLE STAT3
Mean 44.3
Standard deviation 6
Values 40 49
[14]
liver STAT3
Mean 227
Standard deviation 42
Values 1.9e+02 2.3e+02 2.8e+02 2e+02
[15]
ref_hepatocyte STAT1
Mean 20.3
Standard deviation 8.7
Values 17 35 19 12 18
[16]
HepG2 STAT1
Mean 42.7
Standard deviation 9.4
Values 36 49
[17]
HepG2.C3A STAT1
Mean 20.1
Standard deviation 7.2
Values 15 25
[18]
HuH.7 STAT1
Mean 41.6
Standard deviation 4.5
Values 47 38 40
[19]
SNU475 STAT1
Mean 216
Standard deviation 1.4e+02
Values 3.2e+02 1.1e+02
[20]
THLE STAT1
Mean 50.3
Standard deviation 2.1
Values 49 52
[21]
liver STAT1
Mean 55.8
Standard deviation 15
Values 49 69 67 38
[22]
ref_hepatocyte IL6ST
Mean 16.5
Standard deviation 5.8
Values 24 18 9.5 12 19
[23]
HepG2 IL6ST
Mean 43.6
Standard deviation 25
Values 26 61
[24]
HepG2.C3A IL6ST
Mean 92.3
Standard deviation 8.3
Values 86 98
[25]
HuH.7 IL6ST
Mean 63.5
Standard deviation 38
Values 50 1.1e+02 35
[26]
SNU475 IL6ST
Mean 100
Standard deviation 15
Values 90 1.1e+02
[27]
THLE IL6ST
Mean 252
Standard deviation 68
Values 3e+02 2e+02
[28]
liver IL6ST
Mean 321
Standard deviation 1.1e+02
Values 2.5e+02 4.2e+02 2.1e+02 4.1e+02
[29]
ref_hepatocyte JAK1
Mean 15.2
Standard deviation 7.8
Values 6.8 27 18 14 10
[30]
HepG2 JAK1
Mean 47.8
Standard deviation 11
Values 40 56
[31]
HepG2.C3A JAK1
Mean 29.8
Standard deviation 1.3
Values 31 29
[32]
HuH.7 JAK1
Mean 32.5
Standard deviation 3.3
Values 36 32 29
[33]
SNU475 JAK1
Mean 43.1
Standard deviation 5.5
Values 47 39
[34]
THLE JAK1
Mean 75.4
Standard deviation 6.9
Values 70 80
[35]
liver JAK1
Mean 62.3
Standard deviation 9.1
Values 54 75 58 62
[36]
ref_hepatocyte TYK2
Mean 4.82
Standard deviation 1.6
Values 2.6 4 5.2 6.8 5.6
[37]
HepG2 TYK2
Mean 23.5
Standard deviation 0.9
Values 23 24
[38]
HepG2.C3A TYK2
Mean 26.8
Standard deviation 2.6
Values 29 25
[39]
HuH.7 TYK2
Mean 28.1
Standard deviation 8.5
Values 35 19 31
[40]
SNU475 TYK2
Mean 14.9
Standard deviation 0.21
Values 15 15
[41]
THLE TYK2
Mean 31.6
Standard deviation 1.6
Values 33 31
[42]
liver TYK2
Mean 27.2
Standard deviation 3.5
Values 31 24 24 30
[43]
ref_hepatocyte IL27
Mean 1.76
Standard deviation 2.6
Values 0 0 0 3.2 5.7
[44]
HepG2 IL27
Mean 0.068
Standard deviation 0.007
Values 0.063 0.073
[45]
HepG2.C3A IL27
Mean 0.188
Standard deviation 0.16
Values 0.3 0.075
[46]
HuH.7 IL27
Mean 1.34
Standard deviation 0.43
Values 0.89 1.7 1.4
[47]
SNU475 IL27
Mean 0
Standard deviation 0
Values 0 0
[48]
THLE IL27
Mean 0.00266
Standard deviation 0.0038
Values 0 0.0053
[49]
liver IL27
Mean 0.776
Standard deviation 0.22
Values 0.94 0.46 0.9 0.81
[50]
ref_hepatocyte EBI3
Mean 1.37
Standard deviation 1.7
Values 0 0.73 4.3 1.1 0.64
[51]
HepG2 EBI3
Mean 1.69
Standard deviation 1.4
Values 2.7 0.72
[52]
HepG2.C3A EBI3
Mean 2.47
Standard deviation 1.4
Values 3.5 1.5
[53]
HuH.7 EBI3
Mean 0.335
Standard deviation 0.16
Values 0.27 0.52 0.22
[54]
SNU475 EBI3
Mean 2.01
Standard deviation 0.1
Values 1.9 2.1
[55]
THLE EBI3
Mean 0.134
Standard deviation 0.0058
Values 0.13 0.14
[56]
liver EBI3
Mean 0.939
Standard deviation 0.7
Values 1.3 0.23 1.7 0.49
[57]
ref_hepatocyte CRLF1
Mean 1.05
Standard deviation 2.3
Values 5.2 0 0 0 0.041
[58]
HepG2 CRLF1
Mean 254
Standard deviation 1.2e+02
Values 3.4e+02 1.7e+02
[59]
HepG2.C3A CRLF1
Mean 132
Standard deviation 17
Values 1.4e+02 1.2e+02
[60]
HuH.7 CRLF1
Mean 1.48
Standard deviation 0.28
Values 1.6 1.2 1.7
[61]
SNU475 CRLF1
Mean 0.245
Standard deviation 0.06
Values 0.29 0.2
[62]
THLE CRLF1
Mean 0.285
Standard deviation 0.16
Values 0.17 0.4
[63]
liver CRLF1
Mean 0.0989
Standard deviation 0.15
Values 0.024 0.029 0.026 0.32
[64]
ref_hepatocyte JAK2
Mean 0.762
Standard deviation 0.48
Values 1.3 1.3 0.62 0.18 0.5
[65]
HepG2 JAK2
Mean 1.97
Standard deviation 1.3
Values 1 2.9
[66]
HepG2.C3A JAK2
Mean 1.75
Standard deviation 0.67
Values 1.3 2.2
[67]
HuH.7 JAK2
Mean 1.23
Standard deviation 0.34
Values 1.2 1.6 0.9
[68]
SNU475 JAK2
Mean 2.37
Standard deviation 0.1
Values 2.3 2.4
[69]
THLE JAK2
Mean 4.02
Standard deviation 0.77
Values 4.6 3.5
[70]
liver JAK2
Mean 7.06
Standard deviation 3.8
Values 4.7 11 2.9 9.8
[71]
ref_hepatocyte IL27RA
Mean 0.619
Standard deviation 0.41
Values 0.43 1.3 0.27 0.52 0.54
[72]
HepG2 IL27RA
Mean 4.95
Standard deviation 0.37
Values 5.2 4.7
[73]
HepG2.C3A IL27RA
Mean 5.97
Standard deviation 0.58
Values 5.6 6.4
[74]
HuH.7 IL27RA
Mean 6.92
Standard deviation 0.27
Values 6.8 6.7 7.2
[75]
SNU475 IL27RA
Mean 0.905
Standard deviation 0.37
Values 0.64 1.2
[76]
THLE IL27RA
Mean 2.89
Standard deviation 0.15
Values 2.8 3
[77]
liver IL27RA
Mean 1.19
Standard deviation 0.32
Values 1.6 0.83 1.1 1.3